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The map label for this gene is argS [H]

Identifier: 194737429

GI number: 194737429

Start: 1980477

End: 1982210

Strand: Direct

Name: argS [H]

Synonym: SeSA_A2064

Alternate gene names: 194737429

Gene position: 1980477-1982210 (Clockwise)

Preceding gene: 194734236

Following gene: 194734378

Centisome position: 42.06

GC content: 55.36

Gene sequence:

>1734_bases
GTGAATATTCAGGCTCTTCTCTCAGAAAAAGTTAGTCAGGCCATGATTGCTGCAGGCGCGCCTGCAGATTGCGAGCCCCA
GGTTCGTCAGTCAGCCAAAGTTCAGTTCGGCGACTATCAGGCCAACGGCATGATGGCAGTTGCGAAAAAACTGGGTATGG
CCCCCCGACAACTTGCAGAGCAGGTGCTGACTCATCTGGATCTCAGCGGCATCGCCAGCAAGGTTGAAATCGCCGGCCCT
GGCTTTATCAATATTTTCCTCGAACCGGCTTTTCTCGCTGAACAGGTGCAACAGGCGCTGGCCTCCGAACGTCTGGGCGT
TTCTCAGCCGACTCGTCAGACGATTGTCGTCGACTACTCCGCGCCCAACGTCGCGAAAGAGATGCACGTCGGTCATCTAC
GCTCCACGATTATCGGCGATGCGGCAGTACGCACGCTGGAGTTTCTGGGCCATCATGTTATTCGCGCTAACCACGTCGGC
GACTGGGGCACCCAGTTCGGTATGCTTATCGCCTGGCTGGAAAAACAGCAGCAGGAAAACGCGGGCGACATGGCGCTGGC
GGATCTCGAAGGATTCTACCGCGATGCGAAAAAGCATTATGACGAAGATGAAGCGTTTGCCGAGCGCGCGCGTAACTACG
TCGTCAAATTGCAGAGCGGTGATACCTATTTCCGTGAGATGTGGCGTAAGCTGGTTGATATCACGATGACGCAAAACCAG
ATCACCTATGATCGTCTGAACGTCACTCTGACGCGTGACGATGTGATGGGCGAAAGTCTGTATAATCCGATGCTGCCGGG
CATCGTCGCCGATCTGAAAGCCAAAGGCCTGGCGGTTGAAAGCGAAGGCGCAACGGTGGTTTTCCTTGATGAGTTTAAAA
ACAAGGAAGGCGACCCGATGGGCGTCATTATTCAGAAGAAAGATGGCGGTTATCTGTATACCACTACCGATATCGCCTGC
GCCAAATACCGTTACGAAACGCTGCACGCCGACCGCGTGCTCTACTACATTGACTCCCGTCAGCACCAGCACCTGATGCA
AGCCTGGACCATTGTGCGCAAAGCCGGTTATGTGCCGGATTCCGTTCCGCTGGAACACCACATGTTCGGCATGATGTTGG
GTAAAGACGGTAAACCGTTTAAAACTCGCGCGGGCGGTACGGTGAAACTGGCGGACCTGCTGGATGAGGCGCTGGAGCGC
GCGCGTCGTCTGGTGGCGGAGAAGAACCCGGATATGCCGGCTGACGAGCTGGAAAAACTGGCTAACGCCGTCGGTATTGG
CGCGGTGAAATACGCCGATCTGTCAAAAAACCGCACCACTGACTATATCTTCGACTGGGATAATATGTTGGCTTTCGAAG
GCAATACCGCTCCTTATATGCAGTATGCCTATACGCGTGTGCTGTCTGTTTTCCGTAAAGCGGACATCGACGAGCAGGCG
CTGGCGAGCGCGCCGGTTATCATTAGCGAAGATCGCGAAGCGCAGCTCGCTGCCCGTCTGCTGCAGTTTGAAGAAACCCT
GACGGTGGTCGCGCGTGAAGGTACGCCGCACGTCATGTGCGCGTATCTGTATGACGTCGCCGGGCTGTTCTCCGGCTTCT
ACGAGCACTGCCCTATTCTCAGCGCCGAGAATGACGCGGTTCGCAATAGCCGCCTAAAACTGGCGCAACTGACGGCGAAA
ACGCTGAAACTGGGTCTGGATACGTTGGGTATCGAAACCGTAGAACGCATGTAA

Upstream 100 bases:

>100_bases
GCGCAATGCTGACGCCAACGGGCATTTGCAGTATACTCCCGCCCTAATTCTTAAACTGGCGCGGGCAATACAGTCCGCTT
CATAAACGTAAGGTATTCCG

Downstream 100 bases:

>100_bases
ACGCGCCGTCGTTAACATCATCAGGCCTGACTCCGGGTAACGGACTCAGGCCTTTTTATTGCCACAGCGGTATATCTGTA
ACAAATCACAAGGAATGACA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MNIQALLSEKVSQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAEQVLTHLDLSGIASKVEIAGP
GFINIFLEPAFLAEQVQQALASERLGVSQPTRQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHHVIRANHVG
DWGTQFGMLIAWLEKQQQENAGDMALADLEGFYRDAKKHYDEDEAFAERARNYVVKLQSGDTYFREMWRKLVDITMTQNQ
ITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGDPMGVIIQKKDGGYLYTTTDIAC
AKYRYETLHADRVLYYIDSRQHQHLMQAWTIVRKAGYVPDSVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALER
ARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKADIDEQA
LASAPVIISEDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDVAGLFSGFYEHCPILSAENDAVRNSRLKLAQLTAK
TLKLGLDTLGIETVERM

Sequences:

>Translated_577_residues
MNIQALLSEKVSQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAEQVLTHLDLSGIASKVEIAGP
GFINIFLEPAFLAEQVQQALASERLGVSQPTRQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHHVIRANHVG
DWGTQFGMLIAWLEKQQQENAGDMALADLEGFYRDAKKHYDEDEAFAERARNYVVKLQSGDTYFREMWRKLVDITMTQNQ
ITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGDPMGVIIQKKDGGYLYTTTDIAC
AKYRYETLHADRVLYYIDSRQHQHLMQAWTIVRKAGYVPDSVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALER
ARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKADIDEQA
LASAPVIISEDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDVAGLFSGFYEHCPILSAENDAVRNSRLKLAQLTAK
TLKLGLDTLGIETVERM
>Mature_577_residues
MNIQALLSEKVSQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAEQVLTHLDLSGIASKVEIAGP
GFINIFLEPAFLAEQVQQALASERLGVSQPTRQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHHVIRANHVG
DWGTQFGMLIAWLEKQQQENAGDMALADLEGFYRDAKKHYDEDEAFAERARNYVVKLQSGDTYFREMWRKLVDITMTQNQ
ITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGDPMGVIIQKKDGGYLYTTTDIAC
AKYRYETLHADRVLYYIDSRQHQHLMQAWTIVRKAGYVPDSVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALER
ARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKADIDEQA
LASAPVIISEDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDVAGLFSGFYEHCPILSAENDAVRNSRLKLAQLTAK
TLKLGLDTLGIETVERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=599, Percent_Identity=37.8964941569282, Blast_Score=389, Evalue=1e-108,
Organism=Homo sapiens, GI197100773, Length=476, Percent_Identity=30.2521008403361, Blast_Score=194, Evalue=3e-49,
Organism=Escherichia coli, GI1788184, Length=577, Percent_Identity=95.6672443674177, Blast_Score=1151, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985061, Length=598, Percent_Identity=37.123745819398, Blast_Score=376, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI71985068, Length=566, Percent_Identity=37.2791519434629, Blast_Score=365, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17532153, Length=384, Percent_Identity=27.6041666666667, Blast_Score=144, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6320548, Length=544, Percent_Identity=33.4558823529412, Blast_Score=246, Evalue=6e-66,
Organism=Saccharomyces cerevisiae, GI6321883, Length=538, Percent_Identity=28.2527881040892, Blast_Score=208, Evalue=2e-54,
Organism=Drosophila melanogaster, GI18859963, Length=567, Percent_Identity=37.2134038800705, Blast_Score=388, Evalue=1e-108,
Organism=Drosophila melanogaster, GI28571570, Length=512, Percent_Identity=28.90625, Blast_Score=164, Evalue=2e-40,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 64291; Mature: 64291

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIQALLSEKVSQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAE
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCEEECCCCCCCHHHHHHHHCCCHHHHHH
QVLTHLDLSGIASKVEIAGPGFINIFLEPAFLAEQVQQALASERLGVSQPTRQTIVVDYS
HHHHHCCHHHCCCEEEECCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC
APNVAKEMHVGHLRSTIIGDAAVRTLEFLGHHVIRANHVGDWGTQFGMLIAWLEKQQQEN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHCC
AGDMALADLEGFYRDAKKHYDEDEAFAERARNYVVKLQSGDTYFREMWRKLVDITMTQNQ
CCCEEHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHEEECCCE
ITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGDPM
EEEEEEEEEEECCHHHHHHHHCCCCCHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCE
GVIIQKKDGGYLYTTTDIACAKYRYETLHADRVLYYIDSRQHQHLMQAWTIVRKAGYVPD
EEEEEECCCCEEEEECCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCC
SVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALERARRLVAEKNPDMPADELEKL
CCCHHHHHHHHHCCCCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ANAVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKADIDEQA
HHHHCCCCEEEECCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHH
LASAPVIISEDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDVAGLFSGFYEHCPIL
HHCCCEEEECCCHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCC
SAENDAVRNSRLKLAQLTAKTLKLGLDTLGIETVERM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCC
>Mature Secondary Structure
MNIQALLSEKVSQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAE
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCEEECCCCCCCHHHHHHHHCCCHHHHHH
QVLTHLDLSGIASKVEIAGPGFINIFLEPAFLAEQVQQALASERLGVSQPTRQTIVVDYS
HHHHHCCHHHCCCEEEECCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC
APNVAKEMHVGHLRSTIIGDAAVRTLEFLGHHVIRANHVGDWGTQFGMLIAWLEKQQQEN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHCC
AGDMALADLEGFYRDAKKHYDEDEAFAERARNYVVKLQSGDTYFREMWRKLVDITMTQNQ
CCCEEHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHEEECCCE
ITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGDPM
EEEEEEEEEEECCHHHHHHHHCCCCCHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCE
GVIIQKKDGGYLYTTTDIACAKYRYETLHADRVLYYIDSRQHQHLMQAWTIVRKAGYVPD
EEEEEECCCCEEEEECCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCC
SVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALERARRLVAEKNPDMPADELEKL
CCCHHHHHHHHHCCCCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ANAVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKADIDEQA
HHHHCCCCEEEECCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHH
LASAPVIISEDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDVAGLFSGFYEHCPIL
HHCCCEEEECCCHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCC
SAENDAVRNSRLKLAQLTAKTLKLGLDTLGIETVERM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA