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The map label for this gene is aer [H]

Identifier: 194737278

GI number: 194737278

Start: 3290282

End: 3291802

Strand: Reverse

Name: aer [H]

Synonym: SeSA_A3407

Alternate gene names: 194737278

Gene position: 3291802-3290282 (Counterclockwise)

Preceding gene: 194735079

Following gene: 194736403

Centisome position: 69.9

GC content: 55.23

Gene sequence:

>1521_bases
ATGTCTTCTCATCCCTACGTCAGCCAGCTAAATACCCCGCTGGATGATGATACCACTCTGATGTCTACGACCGACCTGGA
AAGCTATATCACTCACGCCAATGACACTTTTGTCCAGGTGAGCGGCTATCAGTTAAACGAGTTACTGGCGCAGCCACATA
ATCTGGTGCGTCATCCGGATATGCCGAAAGCTGCCTTCGCAGATATGTGGTACACCCTAAAACAGGGCGAACCGTGGAGC
GGCATTGTGAAAAACCGGCGTAAAAACGGCGACCATTACTGGGTGCGGGCCAACGCGGTACCGATGATACGTGAAGGGCG
TGTGACGGGATATATGTCGATCCGTACCCGCGCCACGGATGATGAGATTGCCGCCGTTGAGCCTTTATATCAGGCGCTAA
ATGAAGGGCGGTGTAATAAACGTATTCATAAAGGCCTGGTGGTTCGTCAGGGTTTGCTGGGCAAACTGCCCGCTATGCCT
GTTCGCTGGCGAGTGCGTAGCATTATGGGGCTAATGGCCGTAATGCTGGCGTTGGCTCTGTTCGGTACGGATGCGTCATG
GCAGGCGTTGCTGTTGGGCGCGTTGGCGATGCTGGCAGGTACGGCGCTATTTGAATGGCAAATTGTGCGTCCCATTGAAA
ATGTGGCGACGCAGGCGCTGAAAGTGGCGACCGGCGAACGCAACAGCGTACAACATCTTAATCGTAGCGATGAGTTGGGG
CTGACGCTGAGGGCCGTAGGGCAGCTTGGCTTGATGTGCCGCTGGCTGATCAATGACGTATCAAGTCAGGTTTCCAGCGT
CAGAAACGGCAGTGAAAGGCTGGCGAAGGGTAACAATGATCTGAACGAACACACCCGTCAGACCGTGGAGAATGTTCAGG
AAACGGTAACGACCATGAACCAGATGGCGGAGTCCGTGAAGCTCAATTCCGAGACGGCTTCCGCTGCGGATAAGCTTTCC
ATGGCGGCCAGTAGCGCGGCGACTCAGGGAGGTGAGGCGATGGATACGGTGATTAAAACGATGGATGATATCGCTCACAG
TACGCAACGTATCGGGACGATCACCACGCTAATTAACGATATCGCTTTTCAGACGAATATCCTGGCGCTGAATGCGGCGG
TAGAAGCGGCGAGAGCGGGCGAGCAGGGGAAAGGGTTTGCCGTGGTTGCTGGCGAGGTACGCCATCTTGCCAGCCGCAGC
GCTAACGCGGCGAACGATATTCGTAAATTAATTGACGCCAGCGCAACAAAGGTGCAGTCAGGCTCCGAGCAGGTTCACGC
CGCAGGCCGTACCATGGATGACATTGTAGCCCAGGTGCAAAATGTCACCCTGCTTATCGCACGTATCAGTCAGTCGACGC
AGGAACAGACAGATGGGCTTTCCAGCCTGACTCGCGCCGTGGACGAGTTGAACCGCATAACCCAGAAAAATGCGGCGCTG
GTGGAAGAGAGCGCACAAGTCTCCGCAATGGTAAAACACCGTGCCAGCCGGCTGGAGGATGCGGTCACGGTACTGCATTA
A

Upstream 100 bases:

>100_bases
CGATCCAGAGCAATTTTAACAACTAAAGATAAATAGATTAGCGCCGAAATAACATCTGAGCGAAAAATTAACATCCAGAT
AACCTGCACAGGACGCTATC

Downstream 100 bases:

>100_bases
GTTTATTTGTAGGTAGCAACGGTAATGACATCCGCCCGGTAGCAACAAGCTTACCGGGCGGATGCGCTCTGATAGAAGGC
GGTGCCTGCCATCACAGAGA

Product: aerotaxis receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 505

Protein sequence:

>506_residues
MSSHPYVSQLNTPLDDDTTLMSTTDLESYITHANDTFVQVSGYQLNELLAQPHNLVRHPDMPKAAFADMWYTLKQGEPWS
GIVKNRRKNGDHYWVRANAVPMIREGRVTGYMSIRTRATDDEIAAVEPLYQALNEGRCNKRIHKGLVVRQGLLGKLPAMP
VRWRVRSIMGLMAVMLALALFGTDASWQALLLGALAMLAGTALFEWQIVRPIENVATQALKVATGERNSVQHLNRSDELG
LTLRAVGQLGLMCRWLINDVSSQVSSVRNGSERLAKGNNDLNEHTRQTVENVQETVTTMNQMAESVKLNSETASAADKLS
MAASSAATQGGEAMDTVIKTMDDIAHSTQRIGTITTLINDIAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRHLASRS
ANAANDIRKLIDASATKVQSGSEQVHAAGRTMDDIVAQVQNVTLLIARISQSTQEQTDGLSSLTRAVDELNRITQKNAAL
VEESAQVSAMVKHRASRLEDAVTVLH

Sequences:

>Translated_506_residues
MSSHPYVSQLNTPLDDDTTLMSTTDLESYITHANDTFVQVSGYQLNELLAQPHNLVRHPDMPKAAFADMWYTLKQGEPWS
GIVKNRRKNGDHYWVRANAVPMIREGRVTGYMSIRTRATDDEIAAVEPLYQALNEGRCNKRIHKGLVVRQGLLGKLPAMP
VRWRVRSIMGLMAVMLALALFGTDASWQALLLGALAMLAGTALFEWQIVRPIENVATQALKVATGERNSVQHLNRSDELG
LTLRAVGQLGLMCRWLINDVSSQVSSVRNGSERLAKGNNDLNEHTRQTVENVQETVTTMNQMAESVKLNSETASAADKLS
MAASSAATQGGEAMDTVIKTMDDIAHSTQRIGTITTLINDIAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRHLASRS
ANAANDIRKLIDASATKVQSGSEQVHAAGRTMDDIVAQVQNVTLLIARISQSTQEQTDGLSSLTRAVDELNRITQKNAAL
VEESAQVSAMVKHRASRLEDAVTVLH
>Mature_505_residues
SSHPYVSQLNTPLDDDTTLMSTTDLESYITHANDTFVQVSGYQLNELLAQPHNLVRHPDMPKAAFADMWYTLKQGEPWSG
IVKNRRKNGDHYWVRANAVPMIREGRVTGYMSIRTRATDDEIAAVEPLYQALNEGRCNKRIHKGLVVRQGLLGKLPAMPV
RWRVRSIMGLMAVMLALALFGTDASWQALLLGALAMLAGTALFEWQIVRPIENVATQALKVATGERNSVQHLNRSDELGL
TLRAVGQLGLMCRWLINDVSSQVSSVRNGSERLAKGNNDLNEHTRQTVENVQETVTTMNQMAESVKLNSETASAADKLSM
AASSAATQGGEAMDTVIKTMDDIAHSTQRIGTITTLINDIAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRHLASRSA
NAANDIRKLIDASATKVQSGSEQVHAAGRTMDDIVAQVQNVTLLIARISQSTQEQTDGLSSLTRAVDELNRITQKNAALV
EESAQVSAMVKHRASRLEDAVTVLH

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=506, Percent_Identity=83.7944664031621, Blast_Score=869, Evalue=0.0,
Organism=Escherichia coli, GI1787690, Length=298, Percent_Identity=39.9328859060403, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI2367378, Length=427, Percent_Identity=38.6416861826698, Blast_Score=211, Evalue=9e-56,
Organism=Escherichia coli, GI1788195, Length=298, Percent_Identity=41.2751677852349, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1788194, Length=249, Percent_Identity=45.3815261044177, Blast_Score=199, Evalue=4e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 55139; Mature: 55008

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSHPYVSQLNTPLDDDTTLMSTTDLESYITHANDTFVQVSGYQLNELLAQPHNLVRHPD
CCCCCCHHHCCCCCCCCCCEEEHHHHHHHHHCCCCCEEEECCCHHHHHHHCCHHHHCCCC
MPKAAFADMWYTLKQGEPWSGIVKNRRKNGDHYWVRANAVPMIREGRVTGYMSIRTRATD
CCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEEECCCCEEECCCEEEEEEEEECCCC
DEIAAVEPLYQALNEGRCNKRIHKGLVVRQGLLGKLPAMPVRWRVRSIMGLMAVMLALAL
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
FGTDASWQALLLGALAMLAGTALFEWQIVRPIENVATQALKVATGERNSVQHLNRSDELG
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCC
LTLRAVGQLGLMCRWLINDVSSQVSSVRNGSERLAKGNNDLNEHTRQTVENVQETVTTMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
QMAESVKLNSETASAADKLSMAASSAATQGGEAMDTVIKTMDDIAHSTQRIGTITTLIND
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRHLASRSANAANDIRKLIDASATKVQS
HHHHHHHEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
GSEQVHAAGRTMDDIVAQVQNVTLLIARISQSTQEQTDGLSSLTRAVDELNRITQKNAAL
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEESAQVSAMVKHRASRLEDAVTVLH
HHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSHPYVSQLNTPLDDDTTLMSTTDLESYITHANDTFVQVSGYQLNELLAQPHNLVRHPD
CCCCCHHHCCCCCCCCCCEEEHHHHHHHHHCCCCCEEEECCCHHHHHHHCCHHHHCCCC
MPKAAFADMWYTLKQGEPWSGIVKNRRKNGDHYWVRANAVPMIREGRVTGYMSIRTRATD
CCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEEECCCCEEECCCEEEEEEEEECCCC
DEIAAVEPLYQALNEGRCNKRIHKGLVVRQGLLGKLPAMPVRWRVRSIMGLMAVMLALAL
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
FGTDASWQALLLGALAMLAGTALFEWQIVRPIENVATQALKVATGERNSVQHLNRSDELG
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCC
LTLRAVGQLGLMCRWLINDVSSQVSSVRNGSERLAKGNNDLNEHTRQTVENVQETVTTMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
QMAESVKLNSETASAADKLSMAASSAATQGGEAMDTVIKTMDDIAHSTQRIGTITTLIND
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRHLASRSANAANDIRKLIDASATKVQS
HHHHHHHEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
GSEQVHAAGRTMDDIVAQVQNVTLLIARISQSTQEQTDGLSSLTRAVDELNRITQKNAAL
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEESAQVSAMVKHRASRLEDAVTVLH
HHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]