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The map label for this gene is nucA [H]

Identifier: 194737240

GI number: 194737240

Start: 1375056

End: 1375910

Strand: Direct

Name: nucA [H]

Synonym: SeSA_A1427

Alternate gene names: 194737240

Gene position: 1375056-1375910 (Clockwise)

Preceding gene: 194734160

Following gene: 194736705

Centisome position: 29.2

GC content: 51.58

Gene sequence:

>855_bases
GTGAATAAGACCATTAATTTGCTAAAATTACTGCCCGTAGTATTATTAAGCGCATGTACTACATCGTATCCTCCCCAGGA
TACAACATCGGCACCCGAGTTACCCCATCGTAACGTACTCGTTCAGCAACCTGATAACTGTAGCGTTGGCTGTCCTCAAG
GAGGAAGTCAACAAACAATCTATCGCCATGTCTATACGCTCAATAATAATAGCGCCACGAAATTTGCCAACTGGGTTGCC
TATAGCGTGACAAAGACCAGCCAGGCAAGCGGTCGCCCGCGGAACTGGGCGCAGGACCCCGATTTACCGCCCTCGGATAC
GTTGGCCCCTTCCGCCTATAAAAATGCCCATGCGCTATTAAAAGTCGACAGGGGACACCAGGCGCCGTTGGCAGGATTGG
GCGGCGTATCGGACTGGCCGTCGTTAAATTATTTATCGAATATTACGCCGCAGAAATCCGCCCTGAATCAGGGAGCATGG
GCTGCACTGGAAAACCGGGTGCGCGAACTTGCCAAACAGGCTGATGTATCTGTAGTGCACGTAGTGACCGGCCCCCTTTT
TGAGCGGCATATCGCCACATTGCCAGAAGATGCGACGGTAGAAATTCCCAGCGGGTACTGGAAGGTTTTATTCACCGGAA
CGGCGCCGTCAAAAAGTGAAGGAAATTACGCTGCGTTTATTATGGATCAGAATACGCCCCGTTCGGCGAATTTTTGCGAC
TATCAGGTTACCGTGGAGGCTATCGAACATAAAACGAAGCCAGTGCTGACGCTGTGGTCTGCCTTGCCTGAAGCGGTAGC
CAGCGAGGTGAAAACGACAAAGGGGAGTCTGGCGCAGAAGTTAGGTTGTCGATGA

Upstream 100 bases:

>100_bases
TGTTGTCTTTAATGATGAGAGTATCTAACGGCTGGTAGGGTAATATAACCAAATTATTACTATCTGAATTATTAGGGCGG
TTATTATTAAGGAAGCAAAA

Downstream 100 bases:

>100_bases
GAAGCGCTATACGGCGCGTAGAAAGATAATGGAGAAACCCTGTCAAGGGTCTTGATTTGCTACAGAGTGATGCAATCTCC
CTTTTTTTAGTGTTACCATC

Product: DNA/RNA non-specific endonuclease

Products: NA

Alternate protein names: Endonuclease [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MNKTINLLKLLPVVLLSACTTSYPPQDTTSAPELPHRNVLVQQPDNCSVGCPQGGSQQTIYRHVYTLNNNSATKFANWVA
YSVTKTSQASGRPRNWAQDPDLPPSDTLAPSAYKNAHALLKVDRGHQAPLAGLGGVSDWPSLNYLSNITPQKSALNQGAW
AALENRVRELAKQADVSVVHVVTGPLFERHIATLPEDATVEIPSGYWKVLFTGTAPSKSEGNYAAFIMDQNTPRSANFCD
YQVTVEAIEHKTKPVLTLWSALPEAVASEVKTTKGSLAQKLGCR

Sequences:

>Translated_284_residues
MNKTINLLKLLPVVLLSACTTSYPPQDTTSAPELPHRNVLVQQPDNCSVGCPQGGSQQTIYRHVYTLNNNSATKFANWVA
YSVTKTSQASGRPRNWAQDPDLPPSDTLAPSAYKNAHALLKVDRGHQAPLAGLGGVSDWPSLNYLSNITPQKSALNQGAW
AALENRVRELAKQADVSVVHVVTGPLFERHIATLPEDATVEIPSGYWKVLFTGTAPSKSEGNYAAFIMDQNTPRSANFCD
YQVTVEAIEHKTKPVLTLWSALPEAVASEVKTTKGSLAQKLGCR
>Mature_284_residues
MNKTINLLKLLPVVLLSACTTSYPPQDTTSAPELPHRNVLVQQPDNCSVGCPQGGSQQTIYRHVYTLNNNSATKFANWVA
YSVTKTSQASGRPRNWAQDPDLPPSDTLAPSAYKNAHALLKVDRGHQAPLAGLGGVSDWPSLNYLSNITPQKSALNQGAW
AALENRVRELAKQADVSVVHVVTGPLFERHIATLPEDATVEIPSGYWKVLFTGTAPSKSEGNYAAFIMDQNTPRSANFCD
YQVTVEAIEHKTKPVLTLWSALPEAVASEVKTTKGSLAQKLGCR

Specific function: Catalyzes the hydrolysis of both DNA and RNA, double- or single-stranded, at the 3'position of the phosphodiester bond to produce 5'-phosphorylated mono-, di-, tri- and tetranucleotides. DNA is a slightly better substrate than RNA [H]

COG id: COG1864

COG function: function code F; DNA/RNA endonuclease G, NUC1

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA/RNA non-specific endonuclease family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018524
- InterPro:   IPR001604
- InterPro:   IPR020821 [H]

Pfam domain/function: PF01223 Endonuclease_NS [H]

EC number: =3.1.30.2 [H]

Molecular weight: Translated: 30804; Mature: 30804

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS01070 NUCLEASE_NON_SPEC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTINLLKLLPVVLLSACTTSYPPQDTTSAPELPHRNVLVQQPDNCSVGCPQGGSQQTI
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEE
YRHVYTLNNNSATKFANWVAYSVTKTSQASGRPRNWAQDPDLPPSDTLAPSAYKNAHALL
EEEEEEECCCCHHHHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCEEEE
KVDRGHQAPLAGLGGVSDWPSLNYLSNITPQKSALNQGAWAALENRVRELAKQADVSVVH
EECCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCEEEE
VVTGPLFERHIATLPEDATVEIPSGYWKVLFTGTAPSKSEGNYAAFIMDQNTPRSANFCD
EECCHHHHHHHHCCCCCCEEEECCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCC
YQVTVEAIEHKTKPVLTLWSALPEAVASEVKTTKGSLAQKLGCR
CEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKTINLLKLLPVVLLSACTTSYPPQDTTSAPELPHRNVLVQQPDNCSVGCPQGGSQQTI
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEE
YRHVYTLNNNSATKFANWVAYSVTKTSQASGRPRNWAQDPDLPPSDTLAPSAYKNAHALL
EEEEEEECCCCHHHHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCEEEE
KVDRGHQAPLAGLGGVSDWPSLNYLSNITPQKSALNQGAWAALENRVRELAKQADVSVVH
EECCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCEEEE
VVTGPLFERHIATLPEDATVEIPSGYWKVLFTGTAPSKSEGNYAAFIMDQNTPRSANFCD
EECCHHHHHHHHCCCCCCEEEECCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCC
YQVTVEAIEHKTKPVLTLWSALPEAVASEVKTTKGSLAQKLGCR
CEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3319779; 8373817; 2665765; 8078761; 7804150; 8758988; 7664065; 9257723 [H]