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The map label for this gene is uxuR [H]

Identifier: 194736884

GI number: 194736884

Start: 1584038

End: 1584709

Strand: Direct

Name: uxuR [H]

Synonym: SeSA_A1645

Alternate gene names: 194736884

Gene position: 1584038-1584709 (Clockwise)

Preceding gene: 194737677

Following gene: 194734884

Centisome position: 33.64

GC content: 46.88

Gene sequence:

>672_bases
ATGGTTATACCTGAGGTCAGGCAGGAGAGGCTCTATCAGAAGATAGCCAACCTCATCATTAAGCTGATCAATGATAATAT
TTTTCCCCCGGGAACTTTTTTACCGCCAGAACGCGAACTGGCAAAACAGCTTGGCGTGAGCCGCGCCTCCTTGCGAGAAG
CCCTTATTGTACTGGAGATCTCCGGATGGATCGTGATTCAGTCCGGTAATGGGGTTATCGTTTCAGATAAAAAACACCTT
GCCAGCGACTATACCATCGAAGAAATTCTCTCTACTCGCGAGCTGGTCGATAGCCATTGTGCGCGCTTAGCCGCACAAAA
CGATAACGTTGACGTCATCAACCAAATAGAGGCGATTTATCATCGTATGGATCAAGCCATTAACGATAATAACGTCCACG
GCTTTTACTCGCTGGATAAAGAATTTCACCTTGCGATCTCTGAGGCCAGCCGTAACCGGGTGTTGTTCGATATGTCCCGT
ATGTTATGGGAACAACGGATTAATATCCCTTATGCCGGGCTTGATGAGCAGTCTGGAGACAGAAATGTTTTACTTAATCT
CAACAAACAACATAAAGCGATAGTGGATGCGATGCGCCAGTCTGATGCTGACAGCGCCTATGAGGGATCTCTGGAACATT
TACGCTATGTGAGAAAGATTGTCGGCGGCTAA

Upstream 100 bases:

>100_bases
CTTCTCTTTATCATGCACGGTAATTAATTATCACGATCACCAGCGCCAGGATGGTATGCTAAATCCATTCAAAATCCCCT
GGATATGGATTGGAGGGCGC

Downstream 100 bases:

>100_bases
GTTTGTCGATGAATAACACCGCATGGCGGTCATGCCATGCGGTAGAACTCGCCGTAAATCAATGGAAAACAGCATTAATC
TTTAAGTAGCGCTCCGGATA

Product: putative regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MVIPEVRQERLYQKIANLIIKLINDNIFPPGTFLPPERELAKQLGVSRASLREALIVLEISGWIVIQSGNGVIVSDKKHL
ASDYTIEEILSTRELVDSHCARLAAQNDNVDVINQIEAIYHRMDQAINDNNVHGFYSLDKEFHLAISEASRNRVLFDMSR
MLWEQRINIPYAGLDEQSGDRNVLLNLNKQHKAIVDAMRQSDADSAYEGSLEHLRYVRKIVGG

Sequences:

>Translated_223_residues
MVIPEVRQERLYQKIANLIIKLINDNIFPPGTFLPPERELAKQLGVSRASLREALIVLEISGWIVIQSGNGVIVSDKKHL
ASDYTIEEILSTRELVDSHCARLAAQNDNVDVINQIEAIYHRMDQAINDNNVHGFYSLDKEFHLAISEASRNRVLFDMSR
MLWEQRINIPYAGLDEQSGDRNVLLNLNKQHKAIVDAMRQSDADSAYEGSLEHLRYVRKIVGG
>Mature_223_residues
MVIPEVRQERLYQKIANLIIKLINDNIFPPGTFLPPERELAKQLGVSRASLREALIVLEISGWIVIQSGNGVIVSDKKHL
ASDYTIEEILSTRELVDSHCARLAAQNDNVDVINQIEAIYHRMDQAINDNNVHGFYSLDKEFHLAISEASRNRVLFDMSR
MLWEQRINIPYAGLDEQSGDRNVLLNLNKQHKAIVDAMRQSDADSAYEGSLEHLRYVRKIVGG

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=227, Percent_Identity=31.7180616740088, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87082208, Length=226, Percent_Identity=29.646017699115, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790032, Length=224, Percent_Identity=30.8035714285714, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786303, Length=243, Percent_Identity=27.9835390946502, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789353, Length=219, Percent_Identity=31.0502283105023, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 25347; Mature: 25347

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIPEVRQERLYQKIANLIIKLINDNIFPPGTFLPPERELAKQLGVSRASLREALIVLEI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHEEEEEEE
SGWIVIQSGNGVIVSDKKHLASDYTIEEILSTRELVDSHCARLAAQNDNVDVINQIEAIY
CCEEEEECCCEEEEECHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
HRMDQAINDNNVHGFYSLDKEFHLAISEASRNRVLFDMSRMLWEQRINIPYAGLDEQSGD
HHHHHHCCCCCCCEEEECCCHHEEEEHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
RNVLLNLNKQHKAIVDAMRQSDADSAYEGSLEHLRYVRKIVGG
CEEEEECCHHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHHHCC
>Mature Secondary Structure
MVIPEVRQERLYQKIANLIIKLINDNIFPPGTFLPPERELAKQLGVSRASLREALIVLEI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHEEEEEEE
SGWIVIQSGNGVIVSDKKHLASDYTIEEILSTRELVDSHCARLAAQNDNVDVINQIEAIY
CCEEEEECCCEEEEECHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
HRMDQAINDNNVHGFYSLDKEFHLAISEASRNRVLFDMSRMLWEQRINIPYAGLDEQSGD
HHHHHHCCCCCCCEEEECCCHHEEEEHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
RNVLLNLNKQHKAIVDAMRQSDADSAYEGSLEHLRYVRKIVGG
CEEEEECCHHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]