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The map label for this gene is rtn [H]

Identifier: 194736853

GI number: 194736853

Start: 399917

End: 401467

Strand: Direct

Name: rtn [H]

Synonym: SeSA_A0396

Alternate gene names: 194736853

Gene position: 399917-401467 (Clockwise)

Preceding gene: 194737904

Following gene: 194735095

Centisome position: 8.49

GC content: 49.0

Gene sequence:

>1551_bases
ATGTTGTTTATTGCCGTTCCACTGATCGTCATGATATTGGTGGGGTTACTCGCGGGTATCTTCCAGCTAAAACGAGATAT
CGCCGTCAGCGCCAATACGCTGCTGCGGTTTAGCGCGGATATATCTGCCGCCTCCTGGCAAGTCGCCGGAAAAGCCACCA
GACTGGCTGAGAGTTCCTGTACTGACACGCTGAAAGAACTGTCCAGAACGCGGGCCTTCACTCCTTATGTCCGTGACATT
GGGTTTCTGGAAAATGGTGATATCACTTGCTCCTTTGTCACAGGAACCGAACGCTATCATTTTTCCCGGCTGGCAGGGCT
TTCTTTACCTGCTTCTTATCCGAAACGGTGGTTGCGATCTATCGGTAGTATGGCCGAAGGACCCAATCGCCTTGTTGTGG
TTTATGTGAAAAAAGTAGCAGCGAATAAAGCGGCCTTCGTCATTGTGGACTCGCAGTATGTCCAGGAGCTCATGGAGATA
TTGGCTGCAGAGAGAGCATCAGCCTTTAGCCTGACATTCGGCGCAGGGGAGGCGATTACCAGCGCTGCGACGTTGCGCGG
TAAGGCGTTTTTAACGCAGCGGTTCACCTCAACCGATCACACTATCCAGCTGATGGTGCGAACCCCTTTCTCAACGTTAT
CGGCATACTGGTTACAAAACCTTTTTATTTTTGTTCCGCTGTCATTGTGTCTTTCTGTAGGGATGATGTTGTTCTACAGG
CGCTGGTATTTAAAACGTTTATCTCTGGCCCGGGAGATTGCCAGGGGAATAACGCACAATGAGTTTACGGTACATTATCA
GCCTGTTTTTAATGTTAAACACGGTAGTTGCGGCGGCGTGGAGGCGCTAATGCGCTGGCCGCAACCGGATGGCCGTTTTA
TAACCCCGGATATTTTTATTACCGCCGCAGAAAATGAAGGCATGATTATTCCACTCTCTCGTCATCTGTTCGAACTGATT
GCTCATGACGTAATAAACTGGACTGTACCGGATGATTTCTATATCAGCGTAAATATATCGCCTGCGCATCTTATGGATGA
CGGTTTTATACAAGATATAGAGGCGCTCAGGACTCGTTTGGGAACGATAACGCTTATGTTGGAGCTCACCGAGCGTAGCC
TGATTGTAGAACCTTCACAGGTCGCAGAAAAACTTTCAACGCTCCGTGAAAAAGGCGTGTTAATAGCGATTGATGATTTT
GGGACCGGCTATTGCTCACTCTCCTATCTCCAGCAATTACCTGTAGACTCTCTTAAAATAGACAGAACGTTTATCGATAC
CATTGATACCAGCAGCGATGATGTTCCTGTCCTGGATACTATCATTACGCTGAGTCAGCGACTGGGGCTTAATGTGGTTG
CCGAAGGGGTCAGTACCCAGCACCAATTGCGTTACATCTTAAGCCACGGGGTAGGATTCGTTCAGGGATTTCTTTATGCC
AGGCCGATGGGGGCTAATGACTTTATGAGCTGGCTTGGCAAGTCGGCCCAGAGGCAAAATGGTTTACTCAAGGGGGAAAA
CGGATCCGCGAGCGGCCTGGTGGCTGAATAA

Upstream 100 bases:

>100_bases
TTCTATATTAATGTTACTTTAGTTATCTTATAAAAGCATACAGTGGCAAAAGGAAGGCCGGTAAGAGGGCAATGATTTGA
AAGTAAGAAAGCTATTTCTG

Downstream 100 bases:

>100_bases
TACAGGAGCTCGCTACGGAAAAAAATTCAATAGCGCGATATATCCTGGTAATATGTTTATGCCGTGAAGAAACGTGATAG
CACTGGGGCGGATATTTTTA

Product: cyclic diguanylate phosphodiesterase (EAL) domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MLFIAVPLIVMILVGLLAGIFQLKRDIAVSANTLLRFSADISAASWQVAGKATRLAESSCTDTLKELSRTRAFTPYVRDI
GFLENGDITCSFVTGTERYHFSRLAGLSLPASYPKRWLRSIGSMAEGPNRLVVVYVKKVAANKAAFVIVDSQYVQELMEI
LAAERASAFSLTFGAGEAITSAATLRGKAFLTQRFTSTDHTIQLMVRTPFSTLSAYWLQNLFIFVPLSLCLSVGMMLFYR
RWYLKRLSLAREIARGITHNEFTVHYQPVFNVKHGSCGGVEALMRWPQPDGRFITPDIFITAAENEGMIIPLSRHLFELI
AHDVINWTVPDDFYISVNISPAHLMDDGFIQDIEALRTRLGTITLMLELTERSLIVEPSQVAEKLSTLREKGVLIAIDDF
GTGYCSLSYLQQLPVDSLKIDRTFIDTIDTSSDDVPVLDTIITLSQRLGLNVVAEGVSTQHQLRYILSHGVGFVQGFLYA
RPMGANDFMSWLGKSAQRQNGLLKGENGSASGLVAE

Sequences:

>Translated_516_residues
MLFIAVPLIVMILVGLLAGIFQLKRDIAVSANTLLRFSADISAASWQVAGKATRLAESSCTDTLKELSRTRAFTPYVRDI
GFLENGDITCSFVTGTERYHFSRLAGLSLPASYPKRWLRSIGSMAEGPNRLVVVYVKKVAANKAAFVIVDSQYVQELMEI
LAAERASAFSLTFGAGEAITSAATLRGKAFLTQRFTSTDHTIQLMVRTPFSTLSAYWLQNLFIFVPLSLCLSVGMMLFYR
RWYLKRLSLAREIARGITHNEFTVHYQPVFNVKHGSCGGVEALMRWPQPDGRFITPDIFITAAENEGMIIPLSRHLFELI
AHDVINWTVPDDFYISVNISPAHLMDDGFIQDIEALRTRLGTITLMLELTERSLIVEPSQVAEKLSTLREKGVLIAIDDF
GTGYCSLSYLQQLPVDSLKIDRTFIDTIDTSSDDVPVLDTIITLSQRLGLNVVAEGVSTQHQLRYILSHGVGFVQGFLYA
RPMGANDFMSWLGKSAQRQNGLLKGENGSASGLVAE
>Mature_516_residues
MLFIAVPLIVMILVGLLAGIFQLKRDIAVSANTLLRFSADISAASWQVAGKATRLAESSCTDTLKELSRTRAFTPYVRDI
GFLENGDITCSFVTGTERYHFSRLAGLSLPASYPKRWLRSIGSMAEGPNRLVVVYVKKVAANKAAFVIVDSQYVQELMEI
LAAERASAFSLTFGAGEAITSAATLRGKAFLTQRFTSTDHTIQLMVRTPFSTLSAYWLQNLFIFVPLSLCLSVGMMLFYR
RWYLKRLSLAREIARGITHNEFTVHYQPVFNVKHGSCGGVEALMRWPQPDGRFITPDIFITAAENEGMIIPLSRHLFELI
AHDVINWTVPDDFYISVNISPAHLMDDGFIQDIEALRTRLGTITLMLELTERSLIVEPSQVAEKLSTLREKGVLIAIDDF
GTGYCSLSYLQQLPVDSLKIDRTFIDTIDTSSDDVPVLDTIITLSQRLGLNVVAEGVSTQHQLRYILSHGVGFVQGFLYA
RPMGANDFMSWLGKSAQRQNGLLKGENGSASGLVAE

Specific function: Involved in resistance to phages N4 and lambda [H]

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1788502, Length=455, Percent_Identity=32.3076923076923, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI87081845, Length=474, Percent_Identity=27.6371308016878, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI87081980, Length=456, Percent_Identity=30.4824561403509, Blast_Score=188, Evalue=6e-49,
Organism=Escherichia coli, GI87081743, Length=525, Percent_Identity=26.8571428571429, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1786507, Length=250, Percent_Identity=36.8, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1790496, Length=328, Percent_Identity=30.1829268292683, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI226510982, Length=250, Percent_Identity=34.8, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1787541, Length=255, Percent_Identity=30.5882352941176, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI87081921, Length=252, Percent_Identity=30.1587301587302, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1787055, Length=249, Percent_Identity=30.5220883534137, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788849, Length=254, Percent_Identity=27.9527559055118, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI87082096, Length=250, Percent_Identity=29.2, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787410, Length=155, Percent_Identity=28.3870967741935, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 57188; Mature: 57188

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00136 SUBTILASE_ASP ; PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFIAVPLIVMILVGLLAGIFQLKRDIAVSANTLLRFSADISAASWQVAGKATRLAESSC
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEECCHHHHHHHHHH
TDTLKELSRTRAFTPYVRDIGFLENGDITCSFVTGTERYHFSRLAGLSLPASYPKRWLRS
HHHHHHHHHHCCCCCHHHHCCCEECCCEEEEEEECCCHHHHHHHHCCCCCHHHHHHHHHH
IGSMAEGPNRLVVVYVKKVAANKAAFVIVDSQYVQELMEILAAERASAFSLTFGAGEAIT
HHHHCCCCCCEEEEEEEEHHCCCEEEEEECHHHHHHHHHHHHHCCCCEEEEEECCCHHHH
SAATLRGKAFLTQRFTSTDHTIQLMVRTPFSTLSAYWLQNLFIFVPLSLCLSVGMMLFYR
HHHHHCCHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RWYLKRLSLAREIARGITHNEFTVHYQPVFNVKHGSCGGVEALMRWPQPDGRFITPDIFI
HHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCHHHHHHCCCCCCCEECCEEEE
TAAENEGMIIPLSRHLFELIAHDVINWTVPDDFYISVNISPAHLMDDGFIQDIEALRTRL
EEECCCCEEEEHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHCCCHHHHHHHHHHHHH
GTITLMLELTERSLIVEPSQVAEKLSTLREKGVLIAIDDFGTGYCSLSYLQQLPVDSLKI
HHEEEEEEECCCCEEECHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCEEE
DRTFIDTIDTSSDDVPVLDTIITLSQRLGLNVVAEGVSTQHQLRYILSHGVGFVQGFLYA
CHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHCHHHHHHHHHC
RPMGANDFMSWLGKSAQRQNGLLKGENGSASGLVAE
CCCCHHHHHHHHCCHHHHHCCCEECCCCCCCCCCCC
>Mature Secondary Structure
MLFIAVPLIVMILVGLLAGIFQLKRDIAVSANTLLRFSADISAASWQVAGKATRLAESSC
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEECCHHHHHHHHHH
TDTLKELSRTRAFTPYVRDIGFLENGDITCSFVTGTERYHFSRLAGLSLPASYPKRWLRS
HHHHHHHHHHCCCCCHHHHCCCEECCCEEEEEEECCCHHHHHHHHCCCCCHHHHHHHHHH
IGSMAEGPNRLVVVYVKKVAANKAAFVIVDSQYVQELMEILAAERASAFSLTFGAGEAIT
HHHHCCCCCCEEEEEEEEHHCCCEEEEEECHHHHHHHHHHHHHCCCCEEEEEECCCHHHH
SAATLRGKAFLTQRFTSTDHTIQLMVRTPFSTLSAYWLQNLFIFVPLSLCLSVGMMLFYR
HHHHHCCHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RWYLKRLSLAREIARGITHNEFTVHYQPVFNVKHGSCGGVEALMRWPQPDGRFITPDIFI
HHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCHHHHHHCCCCCCCEECCEEEE
TAAENEGMIIPLSRHLFELIAHDVINWTVPDDFYISVNISPAHLMDDGFIQDIEALRTRL
EEECCCCEEEEHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHCCCHHHHHHHHHHHHH
GTITLMLELTERSLIVEPSQVAEKLSTLREKGVLIAIDDFGTGYCSLSYLQQLPVDSLKI
HHEEEEEEECCCCEEECHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCEEE
DRTFIDTIDTSSDDVPVLDTIITLSQRLGLNVVAEGVSTQHQLRYILSHGVGFVQGFLYA
CHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHCHHHHHHHHHC
RPMGANDFMSWLGKSAQRQNGLLKGENGSASGLVAE
CCCCHHHHHHHHCCHHHHHCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9079933 [H]