Click here to switch to the map view.

The map label for this gene is gmhB [H]

Identifier: 194736696

GI number: 194736696

Start: 290663

End: 291229

Strand: Direct

Name: gmhB [H]

Synonym: SeSA_A0275

Alternate gene names: 194736696

Gene position: 290663-291229 (Clockwise)

Preceding gene: 194735528

Following gene: 194737949

Centisome position: 6.17

GC content: 52.03

Gene sequence:

>567_bases
GTGGCAAAGTCTGTACCCGCAATTTTTCTCGACCGTGACGGCACCATTAATGTGGATCACGGCTACGTACATGAAATCGA
TGCATTTGAGTTTATAGACGGTGTTATTGACGCGATGCGCGAGCTAAAAAAAATGGGCTATGCGCTGGTGGTGGTGACGA
ACCAGTCCGGAATCGCGCGCGGCAAATTCACCGAGGCGCAGTTTGAAACGTTAACCGAATGGATGGACTGGTCGTTGGCG
GATCGCGATGTTGATTTGGACGGCATCTATTATTGTCCTCACCATCCGCAGGGCAGCATAGAAGAGTTCCGTCAGGTATG
TGATTGCCGCAAGCCGCATCCAGGAATGCTTATCTCGGCGCGTGATTTCCTGCATATCGATATGGCGGCTTCTTATATGG
TGGGAGACAAGCTGGAAGATATGCAGGCGGCAGCGGCGGCAAATGTCGGGACAAAAGTGCTGGTGCGTACGGGCAAACCG
GTCACGTCAGAAGCAGAAAACGCGGCGGACTGGGTGTTAAACAGCCTTGCCGATCTGCCATCGGCGATAAAAAAGCAGCA
AAAATAA

Upstream 100 bases:

>100_bases
CCAGACGTCTAAATCAATCAGGCTTTATACGATGAGCACTTTCTTGCCTGCTGAAACATGCGATACTAGCGCCACTTGCT
TTACTCAGGAGCTATAAAAG

Downstream 100 bases:

>100_bases
GCGTTATGGATAAAAGATGAGCGGTTAAAACAAAAATGCATTTTTCCGCTTGTCTTCCTGAACCGACTCCCTATAATGCG
CCTCCATCGACACGGCGGAT

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MAKSVPAIFLDRDGTINVDHGYVHEIDAFEFIDGVIDAMRELKKMGYALVVVTNQSGIARGKFTEAQFETLTEWMDWSLA
DRDVDLDGIYYCPHHPQGSIEEFRQVCDCRKPHPGMLISARDFLHIDMAASYMVGDKLEDMQAAAAANVGTKVLVRTGKP
VTSEAENAADWVLNSLADLPSAIKKQQK

Sequences:

>Translated_188_residues
MAKSVPAIFLDRDGTINVDHGYVHEIDAFEFIDGVIDAMRELKKMGYALVVVTNQSGIARGKFTEAQFETLTEWMDWSLA
DRDVDLDGIYYCPHHPQGSIEEFRQVCDCRKPHPGMLISARDFLHIDMAASYMVGDKLEDMQAAAAANVGTKVLVRTGKP
VTSEAENAADWVLNSLADLPSAIKKQQK
>Mature_187_residues
AKSVPAIFLDRDGTINVDHGYVHEIDAFEFIDGVIDAMRELKKMGYALVVVTNQSGIARGKFTEAQFETLTEWMDWSLAD
RDVDLDGIYYCPHHPQGSIEEFRQVCDCRKPHPGMLISARDFLHIDMAASYMVGDKLEDMQAAAAANVGTKVLVRTGKPV
TSEAENAADWVLNSLADLPSAIKKQQK

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=188, Percent_Identity=95.2127659574468, Blast_Score=381, Evalue=1e-107,
Organism=Escherichia coli, GI87082027, Length=145, Percent_Identity=32.4137931034483, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: 3.1.1.-

Molecular weight: Translated: 20876; Mature: 20745

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSVPAIFLDRDGTINVDHGYVHEIDAFEFIDGVIDAMRELKKMGYALVVVTNQSGIAR
CCCCCCEEEECCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCC
GKFTEAQFETLTEWMDWSLADRDVDLDGIYYCPHHPQGSIEEFRQVCDCRKPHPGMLISA
CCCCHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCCCEEEEC
RDFLHIDMAASYMVGDKLEDMQAAAAANVGTKVLVRTGKPVTSEAENAADWVLNSLADLP
CCEEEEHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
SAIKKQQK
HHHHHCCC
>Mature Secondary Structure 
AKSVPAIFLDRDGTINVDHGYVHEIDAFEFIDGVIDAMRELKKMGYALVVVTNQSGIAR
CCCCCEEEECCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCC
GKFTEAQFETLTEWMDWSLADRDVDLDGIYYCPHHPQGSIEEFRQVCDCRKPHPGMLISA
CCCCHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCCCEEEEC
RDFLHIDMAASYMVGDKLEDMQAAAAANVGTKVLVRTGKPVTSEAENAADWVLNSLADLP
CCEEEEHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
SAIKKQQK
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11108008; 11206551; 11258796 [H]