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The map label for this gene is otsB [H]

Identifier: 194736574

GI number: 194736574

Start: 2002583

End: 2003386

Strand: Reverse

Name: otsB [H]

Synonym: SeSA_A2084

Alternate gene names: 194736574

Gene position: 2003386-2002583 (Counterclockwise)

Preceding gene: 194737043

Following gene: 194736914

Centisome position: 42.54

GC content: 54.23

Gene sequence:

>804_bases
GTGGCAGAACCGTTAACCGTATCCCCCGAACTCACTGCGAACTATGCGTATTTTTTTGACCTTGATGGCACATTGGCAGA
GATAAAGCCTCATCCCGATCAGGTAGTGGTACCGCATAAAATCCTTCAGTTGTTAGACCGTCTCGCGGCGCACAACGCAG
GGGCACTGGCATTGATTTCAGGGCGTTCAATGACTGAGCTGGATGCTTTGGCGAAGCCTTTTCGCTTTCCGCTCGCTGGC
GTTCACGGTGCAGAGCGTCGTGACATCAATGGTAAAACCCATATCGTGCGCCTTCCTGAAGCGGTAGTCCGTGAGGTGGA
GGCGTTATTACGTTCGACGCTTGTAGCGCTGCCCGGAACGGAGCTGGAGACGAAGGGGATGGCGTTTGCGCTGCACTACC
GTCAGGCTCCGGAACATGAAGCGGCGCTATTGGCGCTTGCGCAACACGTTACGCAGCACTGGCCGCAACTGGCGTTGCAG
CCTGGTAAATGTGTTGTGGAAATCAAACCTAAGGGAACCAATAAAGGCGAAGCGATTGCCGCCTTTATGCAGGAGGCGCC
CTTTGCGGGACGGATTCCCGTTTTTGTGGGCGACGATTTGACCGATGAGACTGGCTTTGGCGTGGTGAATCACGCTGGCG
GAATTTCCGTAAAAGTGGGCGTCGGGGCAACCCAGGCGGCATGGCGGCTGGAAAGCGTACCCGATGTCTGGCGCTGGCTG
GAGCAAATCAATTATCCACAACAAGAACAACAAGTAATGAATAACAGGAGAGATGGCTATGAGTCGTTTAGTCGTAGTAT
CTAA

Upstream 100 bases:

>100_bases
GATGGTCTTTCTAAATGGCGAGCAGCGTCACACTGTCTATACTTACATGACTAATGAGACCGTTTGTGAGTCTCAATATG
ATGATAAGGAGGAGACAAGG

Downstream 100 bases:

>100_bases
TCGAATTGCCCCCCCGGATAATAAAGGCGGCGCCGGCGGCCTCGCCGTTGGCGTGCTTGGCGCGCTAAAAGCGGCTGGCG
GGTTGTGGTTCGGCTGGAGT

Product: trehalose-6-phosphate phosphatase

Products: NA

Alternate protein names: TPP; Trehalose 6-phosphate phosphatase; Trehalose-phosphatase [H]

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MAEPLTVSPELTANYAYFFDLDGTLAEIKPHPDQVVVPHKILQLLDRLAAHNAGALALISGRSMTELDALAKPFRFPLAG
VHGAERRDINGKTHIVRLPEAVVREVEALLRSTLVALPGTELETKGMAFALHYRQAPEHEAALLALAQHVTQHWPQLALQ
PGKCVVEIKPKGTNKGEAIAAFMQEAPFAGRIPVFVGDDLTDETGFGVVNHAGGISVKVGVGATQAAWRLESVPDVWRWL
EQINYPQQEQQVMNNRRDGYESFSRSI

Sequences:

>Translated_267_residues
MAEPLTVSPELTANYAYFFDLDGTLAEIKPHPDQVVVPHKILQLLDRLAAHNAGALALISGRSMTELDALAKPFRFPLAG
VHGAERRDINGKTHIVRLPEAVVREVEALLRSTLVALPGTELETKGMAFALHYRQAPEHEAALLALAQHVTQHWPQLALQ
PGKCVVEIKPKGTNKGEAIAAFMQEAPFAGRIPVFVGDDLTDETGFGVVNHAGGISVKVGVGATQAAWRLESVPDVWRWL
EQINYPQQEQQVMNNRRDGYESFSRSI
>Mature_266_residues
AEPLTVSPELTANYAYFFDLDGTLAEIKPHPDQVVVPHKILQLLDRLAAHNAGALALISGRSMTELDALAKPFRFPLAGV
HGAERRDINGKTHIVRLPEAVVREVEALLRSTLVALPGTELETKGMAFALHYRQAPEHEAALLALAQHVTQHWPQLALQP
GKCVVEIKPKGTNKGEAIAAFMQEAPFAGRIPVFVGDDLTDETGFGVVNHAGGISVKVGVGATQAAWRLESVPDVWRWLE
QINYPQQEQQVMNNRRDGYESFSRSI

Specific function: Removes the phosphate from trehalose 6-phosphate to produce free trehalose [H]

COG id: COG1877

COG function: function code G; Trehalose-6-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trehalose phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788207, Length=267, Percent_Identity=73.4082397003745, Blast_Score=406, Evalue=1e-115,
Organism=Drosophila melanogaster, GI19920676, Length=196, Percent_Identity=31.1224489795918, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI221473368, Length=245, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI20129307, Length=245, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24582490, Length=245, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR003337 [H]

Pfam domain/function: PF02358 Trehalose_PPase [H]

EC number: =3.1.3.12 [H]

Molecular weight: Translated: 29290; Mature: 29159

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEPLTVSPELTANYAYFFDLDGTLAEIKPHPDQVVVPHKILQLLDRLAAHNAGALALIS
CCCCCCCCCCCCCCEEEEEECCCCCEECCCCCCCEECHHHHHHHHHHHHHCCCCEEEEEC
GRSMTELDALAKPFRFPLAGVHGAERRDINGKTHIVRLPEAVVREVEALLRSTLVALPGT
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCC
ELETKGMAFALHYRQAPEHEAALLALAQHVTQHWPQLALQPGKCVVEIKPKGTNKGEAIA
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHH
AFMQEAPFAGRIPVFVGDDLTDETGFGVVNHAGGISVKVGVGATQAAWRLESVPDVWRWL
HHHHHCCCCCCCCEEECCCCCCCCCCCEEECCCCEEEEECCCCCHHHHHHHCCHHHHHHH
EQINYPQQEQQVMNNRRDGYESFSRSI
HHCCCCHHHHHHHHCCCCHHHHHHCCC
>Mature Secondary Structure 
AEPLTVSPELTANYAYFFDLDGTLAEIKPHPDQVVVPHKILQLLDRLAAHNAGALALIS
CCCCCCCCCCCCCEEEEEECCCCCEECCCCCCCEECHHHHHHHHHHHHHCCCCEEEEEC
GRSMTELDALAKPFRFPLAGVHGAERRDINGKTHIVRLPEAVVREVEALLRSTLVALPGT
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCC
ELETKGMAFALHYRQAPEHEAALLALAQHVTQHWPQLALQPGKCVVEIKPKGTNKGEAIA
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHH
AFMQEAPFAGRIPVFVGDDLTDETGFGVVNHAGGISVKVGVGATQAAWRLESVPDVWRWL
HHHHHCCCCCCCCEEECCCCCCCCCCCEEECCCCEEEEECCCCCHHHHHHHCCHHHHHHH
EQINYPQQEQQVMNNRRDGYESFSRSI
HHCCCCHHHHHHHHCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]