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The map label for this gene is exoX [H]

Identifier: 194735808

GI number: 194735808

Start: 1949633

End: 1950331

Strand: Direct

Name: exoX [H]

Synonym: SeSA_A2032

Alternate gene names: 194735808

Gene position: 1949633-1950331 (Clockwise)

Preceding gene: 194734028

Following gene: 194736750

Centisome position: 41.4

GC content: 51.5

Gene sequence:

>699_bases
ATGTTGCGGATTATAGACACGGAAACCTGCGGGCTGCAGGGCGGGATCGTAGAGATAGCCTCTGTTGATGTCATTGATGG
CAACATTGTCAATCCCATGAGTCACCTGATACGCCCCGATCGCCCTATTACGCCGCAGGCGATGGCGATACACCGTATTA
CCGAAGCCATGGTCGCCGATAAGCCGTGGATTGAAGATGTCATACCGCTTTATTACGGTAGTGAGTGGTATGTCGCTCAC
AATGCCAGTTTCGACAGACGCGTATTACCTGAATTGCCGGGTGAGTGGATCTGTACCATGAAGTTGTCGCGACGCCTGTG
GCCGGGAATAAAATACAGCAATATGGCGCTCTATAAATCGCGCAAACTAAGCGTACAAACGCCGCCGGGGCTGCATCATC
ACCGGGCGCTTTATGATTGCTATATCACCGCCGCCTTGCTGATTGATATTATGCGAACCACCGGCTGGACCGCGGAAGAA
ATGGTCAATATCACGGGCCGTCCTGCGCTGTTAACCACTTTCCCGTTCGGTAAATACCGCGGTAAGGCGGTATCTGAAGT
CGCAAAACGCGATCCGGGCTATTTACGCTGGCTTTTTAATAACCTTGATAATATGAGCCCGGAACTTCGCCTGACGCTTA
AACACTACCTGGAAGATGTTCAGGCTGACGAGCAACGCAGCAATGGAACACCACAATAA

Upstream 100 bases:

>100_bases
CCGATTGCGGTTCGCTATTACTGACGGGCCTGCGCACAACGGAGGGTTGGCAAGGCGATATCATTCCATTACGCTAAGGT
CTTTCGGTGAGGAATGAATC

Downstream 100 bases:

>100_bases
CCCGAGACGCTCACAAGCCGTTGCGGGCGCGCGCGTCTATGCGCTATGTAAGGTTCCCTGCGCCAGGCCGATTAAAAAGG
CGAACTCCAGCGCGACGCCT

Product: exodeoxyribonuclease X

Products: NA

Alternate protein names: Exodeoxyribonuclease X; Exo X; Exonuclease X [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MLRIIDTETCGLQGGIVEIASVDVIDGNIVNPMSHLIRPDRPITPQAMAIHRITEAMVADKPWIEDVIPLYYGSEWYVAH
NASFDRRVLPELPGEWICTMKLSRRLWPGIKYSNMALYKSRKLSVQTPPGLHHHRALYDCYITAALLIDIMRTTGWTAEE
MVNITGRPALLTTFPFGKYRGKAVSEVAKRDPGYLRWLFNNLDNMSPELRLTLKHYLEDVQADEQRSNGTPQ

Sequences:

>Translated_232_residues
MLRIIDTETCGLQGGIVEIASVDVIDGNIVNPMSHLIRPDRPITPQAMAIHRITEAMVADKPWIEDVIPLYYGSEWYVAH
NASFDRRVLPELPGEWICTMKLSRRLWPGIKYSNMALYKSRKLSVQTPPGLHHHRALYDCYITAALLIDIMRTTGWTAEE
MVNITGRPALLTTFPFGKYRGKAVSEVAKRDPGYLRWLFNNLDNMSPELRLTLKHYLEDVQADEQRSNGTPQ
>Mature_232_residues
MLRIIDTETCGLQGGIVEIASVDVIDGNIVNPMSHLIRPDRPITPQAMAIHRITEAMVADKPWIEDVIPLYYGSEWYVAH
NASFDRRVLPELPGEWICTMKLSRRLWPGIKYSNMALYKSRKLSVQTPPGLHHHRALYDCYITAALLIDIMRTTGWTAEE
MVNITGRPALLTTFPFGKYRGKAVSEVAKRDPGYLRWLFNNLDNMSPELRLTLKHYLEDVQADEQRSNGTPQ

Specific function: Capable of degrading both single-strand and double- strand DNA with 3' to 5' polarity. Has higher affinity for ssDNA ends than for dsDNA. May facilitate recombinational repair by pre- synaptic and/or post-synaptic DNA degradation [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788149, Length=219, Percent_Identity=90.8675799086758, Blast_Score=427, Evalue=1e-121,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: 3.1.11.- [C]

Molecular weight: Translated: 26478; Mature: 26478

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRIIDTETCGLQGGIVEIASVDVIDGNIVNPMSHLIRPDRPITPQAMAIHRITEAMVAD
CEEEEECCCCCCCCCEEEEEEEEEECCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
KPWIEDVIPLYYGSEWYVAHNASFDRRVLPELPGEWICTMKLSRRLWPGIKYSNMALYKS
CCCHHHHHHHEECCEEEEEECCCCCCCHHHCCCCCEEEHHHHHHHHCCCCCCCCEEEEEC
RKLSVQTPPGLHHHRALYDCYITAALLIDIMRTTGWTAEEMVNITGRPALLTTFPFGKYR
CCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEECCCCHHC
GKAVSEVAKRDPGYLRWLFNNLDNMSPELRLTLKHYLEDVQADEQRSNGTPQ
CHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLRIIDTETCGLQGGIVEIASVDVIDGNIVNPMSHLIRPDRPITPQAMAIHRITEAMVAD
CEEEEECCCCCCCCCEEEEEEEEEECCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
KPWIEDVIPLYYGSEWYVAHNASFDRRVLPELPGEWICTMKLSRRLWPGIKYSNMALYKS
CCCHHHHHHHEECCEEEEEECCCCCCCHHHCCCCCEEEHHHHHHHHCCCCCCCCEEEEEC
RKLSVQTPPGLHHHRALYDCYITAALLIDIMRTTGWTAEEMVNITGRPALLTTFPFGKYR
CCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEECCCCHHC
GKAVSEVAKRDPGYLRWLFNNLDNMSPELRLTLKHYLEDVQADEQRSNGTPQ
CHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]