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The map label for this gene is ygdL [H]

Identifier: 194735781

GI number: 194735781

Start: 3043119

End: 3043925

Strand: Reverse

Name: ygdL [H]

Synonym: SeSA_A3150

Alternate gene names: 194735781

Gene position: 3043925-3043119 (Counterclockwise)

Preceding gene: 194734822

Following gene: 194736466

Centisome position: 64.64

GC content: 55.51

Gene sequence:

>807_bases
ATGTCAGTGGTGATAAGTGATGCCTGGCGCCAACGCTTTGGCGGCACCGCGCGTCTGTATGGTGAAAAAGCGCTGCAGCG
GTTTGCTGAGGCGCATATCTGCGTCGTAGGAATCGGCGGGGTGGGATCATGGGCGGCAGAGGCGCTGGCGCGTACGGGCA
TCGGCGCGATTACGCTGATTGATATGGACGATGTCTGCGTGACCAATACGAACCGTCAGATCCATGCGTTGCGTGATAAC
GTCGGGTTGGCGAAAGCGGAAGTGATGGCCGAACGGATTCGTCAAATTAACCCGGAGTGCCGGGTAACGGTTATCGATGA
TTTCATCACGCCGGATAATGTGGCGGGTTATATGGACGCGGGTTTTACCTATGTCATTGACGCCATTGACAGCGTTCGTC
CAAAAGCCGCGCTGATTGCGTACTGTCGCCGATATAAGGTTCCTTTAGTGACCACTGGCGGCGCAGGCGGGCAGATCGAT
CCGACGCAAATCCAGGTCGCTGATTTGGCGAAAACCATCCAGGATCCGCTGGCGGCAAAACTGCGTGAGAGATTGAAACA
TAATTTTGGCGTAGTGAAGAACAGTAAAGGTAAACTGGGCGTGGACTGCGTTTTTTCCACTGAAGCGCTGGTTTACCCAC
AGGCGGACGGTTCCGTATGCGCGATGAAAGCTACCGCAGAAGGGCCAAAACGGATGGATTGCGCCTCTGGCTTCGGCGCG
GCGACGATGGTGACGGCAACGTTCGGTTTTGTCGCCGTTTCCCATGCGCTGAAGAAGATCATGGCTAAAGCGGCGCGACA
AGAATAA

Upstream 100 bases:

>100_bases
TCTGCGACAACCGGATTGCCCGATAACGCGATCGCTATCGGGCCTGAAAATAGTGAGCAGGGGTGAGGAATAACCTCACC
TTTTTTTATTCTGAGGTCAT

Downstream 100 bases:

>100_bases
AAGGACGGGGCGGAGTGTCACGCAGACGCGTATCCGGCCCTGCGCCCTTTGTTAGCGAAAGAAGCGCTGTACCCTGCCGA
ACACCGGTTTCAGACGGGCG

Product: ThiF family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MSVVISDAWRQRFGGTARLYGEKALQRFAEAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDN
VGLAKAEVMAERIRQINPECRVTVIDDFITPDNVAGYMDAGFTYVIDAIDSVRPKAALIAYCRRYKVPLVTTGGAGGQID
PTQIQVADLAKTIQDPLAAKLRERLKHNFGVVKNSKGKLGVDCVFSTEALVYPQADGSVCAMKATAEGPKRMDCASGFGA
ATMVTATFGFVAVSHALKKIMAKAARQE

Sequences:

>Translated_268_residues
MSVVISDAWRQRFGGTARLYGEKALQRFAEAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDN
VGLAKAEVMAERIRQINPECRVTVIDDFITPDNVAGYMDAGFTYVIDAIDSVRPKAALIAYCRRYKVPLVTTGGAGGQID
PTQIQVADLAKTIQDPLAAKLRERLKHNFGVVKNSKGKLGVDCVFSTEALVYPQADGSVCAMKATAEGPKRMDCASGFGA
ATMVTATFGFVAVSHALKKIMAKAARQE
>Mature_267_residues
SVVISDAWRQRFGGTARLYGEKALQRFAEAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNV
GLAKAEVMAERIRQINPECRVTVIDDFITPDNVAGYMDAGFTYVIDAIDSVRPKAALIAYCRRYKVPLVTTGGAGGQIDP
TQIQVADLAKTIQDPLAAKLRERLKHNFGVVKNSKGKLGVDCVFSTEALVYPQADGSVCAMKATAEGPKRMDCASGFGAA
TMVTATFGFVAVSHALKKIMAKAARQE

Specific function: Unknown

COG id: COG1179

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI4885649, Length=131, Percent_Identity=35.1145038167939, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI38045948, Length=153, Percent_Identity=29.4117647058824, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789177, Length=267, Percent_Identity=93.6329588014981, Blast_Score=519, Evalue=1e-149,
Organism=Escherichia coli, GI87082356, Length=136, Percent_Identity=30.1470588235294, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787048, Length=131, Percent_Identity=32.824427480916, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321790, Length=205, Percent_Identity=25.3658536585366, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322825, Length=201, Percent_Identity=31.3432835820896, Blast_Score=92, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24582879, Length=132, Percent_Identity=31.0606060606061, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24660640, Length=133, Percent_Identity=30.8270676691729, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 28652; Mature: 28521

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVVISDAWRQRFGGTARLYGEKALQRFAEAHICVVGIGGVGSWAAEALARTGIGAITLI
CEEEECHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCEEEEE
DMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRVTVIDDFITPDNVAGYMDA
ECCCEEEECCCCEEEEHHHCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHC
GFTYVIDAIDSVRPKAALIAYCRRYKVPLVTTGGAGGQIDPTQIQVADLAKTIQDPLAAK
CHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
LRERLKHNFGVVKNSKGKLGVDCVFSTEALVYPQADGSVCAMKATAEGPKRMDCASGFGA
HHHHHHHHCCCEECCCCCCCEEEEEECCEEEEECCCCCEEEEEECCCCCCCCHHHCCCCH
ATMVTATFGFVAVSHALKKIMAKAARQE
HHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVVISDAWRQRFGGTARLYGEKALQRFAEAHICVVGIGGVGSWAAEALARTGIGAITLI
EEEECHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCEEEEE
DMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRVTVIDDFITPDNVAGYMDA
ECCCEEEECCCCEEEEHHHCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHC
GFTYVIDAIDSVRPKAALIAYCRRYKVPLVTTGGAGGQIDPTQIQVADLAKTIQDPLAAK
CHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
LRERLKHNFGVVKNSKGKLGVDCVFSTEALVYPQADGSVCAMKATAEGPKRMDCASGFGA
HHHHHHHHCCCEECCCCCCCEEEEEECCEEEEECCCCCEEEEEECCCCCCCCHHHCCCCH
ATMVTATFGFVAVSHALKKIMAKAARQE
HHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]