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The map label for this gene is recD [H]

Identifier: 194734822

GI number: 194734822

Start: 3048552

End: 3050387

Strand: Reverse

Name: recD [H]

Synonym: SeSA_A3156

Alternate gene names: 194734822

Gene position: 3050387-3048552 (Counterclockwise)

Preceding gene: 194736312

Following gene: 194735781

Centisome position: 64.78

GC content: 58.33

Gene sequence:

>1836_bases
ATGACAATCCAGGAGCGGTTGCTGGAGGCCGTTGAACAAAAACTCTTACGGCCCATTGATGCCCAGTTTGCTTTAACCGT
CGCCGGTAACGACGATCCCGCCGTGACGCTGGCGGCAGCGCTGCTTAGTCATGACGCAGGTGAAGGTCACGTGTGTCTGC
CGTTGTCGCGTTTAACGTTAACGGAGGAGGCGCATCCCTTACTGGTCGCCTGGATAAGCGAAACGGCTACGCCAATCGAC
TGGAAAAAGCGGTTATTGGCGTCTGCGGCGGTTAGCTGCGGCGATAGCCCCGCGCCGTTAATTCTGTGCGGCGATCGTCT
CTACCTGAATCGCATGTGGTGCAACGAGCGTACGGTTGCGCGCTTTTTTAACGAGGTTAACCAGGCCATCGCCGTAGATG
AAGATCAGTTATCCCGTATTCTGGACGCGCTATTCCCTCCGACAGACGAGGTGAACTGGCAAAAGGTGGCCGCCGCCGTA
GCGCTAACTCGCCGTATCTCCGTGATTTCAGGCGGTCCCGGTACCGGTAAAACCACCACCGTCGCGAAGCTGCTGGCGGC
ATTAATTCAAATGGCGGATGGCGAACGTTGCCGTATCCGGCTGGCGGCACCGACCGGGAAAGCGGCCGCACGCCTGACGG
AGTCGCTCGGCGCGGCGTTGCGTCAGCTTCCTCTTACCGATGCGCAGAAAAAGCGTATACCGGAGGACGCCAGTACGCTG
CACCGACTGCTGGGCGCACAGCCCGGCAGCCAGCGATTACGCCATCATGCGGGCAACCCGCTGCATCTGGACGTGCTGGT
GGTCGATGAAGCATCAATGATTGATTTGCCGATGATGTCACGTTTGATTGACGCTCTGCCGCCGCACGGGCGGGTCATTT
TTCTTGGCGATCGCGATCAGTTGGCATCCGTTGAGGCGGGTGCTGTGTTGGGCGATATTTGCGCCTATGTCAACGCAGGG
TTTACGGCGGAACGCGCCCGACAGCTAAGTCGACTAACAGGGAGCGCCATTCCGGCGGGGGCCGGAACGCAAGCCGCGTC
TTTACGCGATAGCCTCTGTTTGTTGCAAAAGAGCTATCGTTTCGGCAGCGATTCTGGCATCGGCAAGCTGGCGGCGGCGA
TTAACTGCGGCGACAGGTCGGCAATCCAGGCTGTTTTTCAGCAGGGGTTTAGCGATATAGAGAAGCGTACATTGCAAAGC
AGCGACGATTATGCCGGGATGCTGGATGAAGCGCTGGCGGGCTATGGTCGCTACCTGCGGTTGCTGCATGAAAAAGCAAC
GCCGGAGGCAATCCTTCAGGCTTTCAATGAGTATCAACTGCTTTGCGCGCTGCGCGAAGGCCCATTTGGCGTGAGGGGAC
TGAATGACCGCATTGAGCAGGCGATGGTGCAGCAACGAAAAATTCAGCGGCATCCGCACTCTCGCTGGTATGAAGGGCGT
CCGGTAATGATTGCGCGCAACGATAGCGCGTTGGGGCTATTTAACGGCGATATTGGTATTGCGCTCGATCGCGGGCAGGG
GTTACGCGTCTGGTTTGTGATGCCGGACGGCACGATCAAGTCCGTTCAGCCCAGCCGTCTGCCGGAACATGATACAACCT
GGGCGATGACGGTACATAAATCACAGGGGTCTGAATTTGATCACGCCGCGCTGATTTTACCCAGCCAGCGTTCGCCGGTC
GTGACGCGGGAGCTGGTGTATACCGCTGTTACGCGGGCGCGGCGGCGGTTATCGCTGTATGCCGATGAACGGATCCTGGC
AAGCGCGATTGTGACGCGTACGGAGCGGCGCAGCGGATTAGCCACCTTATTTGATGAAGTCAGTCGTACCGGATAA

Upstream 100 bases:

>100_bases
GCGAACGTCCGCAGCAGGGTATTTTTACCACTCGCCCTGCGGCGGCGTTAATTAACCAACTGGATGATATGTTTGCAGGT
GAAATGAGTGAGGAGGCGCA

Downstream 100 bases:

>100_bases
GACGAGTTCTCGCCGGATGGTGACGCGTAGCGTCTTATCCGGCCTCCAAATGATGCTTTCGAGCGTAGGCCTGATAAGCG
CAGCGCCATCAGTCCCCTCT

Product: exonuclease V subunit alpha

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 611; Mature: 610

Protein sequence:

>611_residues
MTIQERLLEAVEQKLLRPIDAQFALTVAGNDDPAVTLAAALLSHDAGEGHVCLPLSRLTLTEEAHPLLVAWISETATPID
WKKRLLASAAVSCGDSPAPLILCGDRLYLNRMWCNERTVARFFNEVNQAIAVDEDQLSRILDALFPPTDEVNWQKVAAAV
ALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGAALRQLPLTDAQKKRIPEDASTL
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPPHGRVIFLGDRDQLASVEAGAVLGDICAYVNAG
FTAERARQLSRLTGSAIPAGAGTQAASLRDSLCLLQKSYRFGSDSGIGKLAAAINCGDRSAIQAVFQQGFSDIEKRTLQS
SDDYAGMLDEALAGYGRYLRLLHEKATPEAILQAFNEYQLLCALREGPFGVRGLNDRIEQAMVQQRKIQRHPHSRWYEGR
PVMIARNDSALGLFNGDIGIALDRGQGLRVWFVMPDGTIKSVQPSRLPEHDTTWAMTVHKSQGSEFDHAALILPSQRSPV
VTRELVYTAVTRARRRLSLYADERILASAIVTRTERRSGLATLFDEVSRTG

Sequences:

>Translated_611_residues
MTIQERLLEAVEQKLLRPIDAQFALTVAGNDDPAVTLAAALLSHDAGEGHVCLPLSRLTLTEEAHPLLVAWISETATPID
WKKRLLASAAVSCGDSPAPLILCGDRLYLNRMWCNERTVARFFNEVNQAIAVDEDQLSRILDALFPPTDEVNWQKVAAAV
ALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGAALRQLPLTDAQKKRIPEDASTL
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPPHGRVIFLGDRDQLASVEAGAVLGDICAYVNAG
FTAERARQLSRLTGSAIPAGAGTQAASLRDSLCLLQKSYRFGSDSGIGKLAAAINCGDRSAIQAVFQQGFSDIEKRTLQS
SDDYAGMLDEALAGYGRYLRLLHEKATPEAILQAFNEYQLLCALREGPFGVRGLNDRIEQAMVQQRKIQRHPHSRWYEGR
PVMIARNDSALGLFNGDIGIALDRGQGLRVWFVMPDGTIKSVQPSRLPEHDTTWAMTVHKSQGSEFDHAALILPSQRSPV
VTRELVYTAVTRARRRLSLYADERILASAIVTRTERRSGLATLFDEVSRTG
>Mature_610_residues
TIQERLLEAVEQKLLRPIDAQFALTVAGNDDPAVTLAAALLSHDAGEGHVCLPLSRLTLTEEAHPLLVAWISETATPIDW
KKRLLASAAVSCGDSPAPLILCGDRLYLNRMWCNERTVARFFNEVNQAIAVDEDQLSRILDALFPPTDEVNWQKVAAAVA
LTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGAALRQLPLTDAQKKRIPEDASTLH
RLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPPHGRVIFLGDRDQLASVEAGAVLGDICAYVNAGF
TAERARQLSRLTGSAIPAGAGTQAASLRDSLCLLQKSYRFGSDSGIGKLAAAINCGDRSAIQAVFQQGFSDIEKRTLQSS
DDYAGMLDEALAGYGRYLRLLHEKATPEAILQAFNEYQLLCALREGPFGVRGLNDRIEQAMVQQRKIQRHPHSRWYEGRP
VMIARNDSALGLFNGDIGIALDRGQGLRVWFVMPDGTIKSVQPSRLPEHDTTWAMTVHKSQGSEFDHAALILPSQRSPVV
TRELVYTAVTRARRRLSLYADERILASAIVTRTERRSGLATLFDEVSRTG

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=604, Percent_Identity=84.6026490066225, Blast_Score=1023, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 66609; Mature: 66478

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIQERLLEAVEQKLLRPIDAQFALTVAGNDDPAVTLAAALLSHDAGEGHVCLPLSRLTL
CCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEHHHEE
TEEAHPLLVAWISETATPIDWKKRLLASAAVSCGDSPAPLILCGDRLYLNRMWCNERTVA
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEHHHHCCHHHHH
RFFNEVNQAIAVDEDQLSRILDALFPPTDEVNWQKVAAAVALTRRISVISGGPGTGKTTT
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCCHHH
VAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGAALRQLPLTDAQKKRIPEDASTL
HHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHH
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPPHGRVIFLGDRDQ
HHHHCCCCCHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCHH
LASVEAGAVLGDICAYVNAGFTAERARQLSRLTGSAIPAGAGTQAASLRDSLCLLQKSYR
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHC
FGSDSGIGKLAAAINCGDRSAIQAVFQQGFSDIEKRTLQSSDDYAGMLDEALAGYGRYLR
CCCCCCHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LLHEKATPEAILQAFNEYQLLCALREGPFGVRGLNDRIEQAMVQQRKIQRHPHSRWYEGR
HHHHCCCHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
PVMIARNDSALGLFNGDIGIALDRGQGLRVWFVMPDGTIKSVQPSRLPEHDTTWAMTVHK
EEEEEECCCEEEEEECCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEC
SQGSEFDHAALILPSQRSPVVTRELVYTAVTRARRRLSLYADERILASAIVTRTERRSGL
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
ATLFDEVSRTG
HHHHHHHHCCC
>Mature Secondary Structure 
TIQERLLEAVEQKLLRPIDAQFALTVAGNDDPAVTLAAALLSHDAGEGHVCLPLSRLTL
CHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEHHHEE
TEEAHPLLVAWISETATPIDWKKRLLASAAVSCGDSPAPLILCGDRLYLNRMWCNERTVA
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEHHHHCCHHHHH
RFFNEVNQAIAVDEDQLSRILDALFPPTDEVNWQKVAAAVALTRRISVISGGPGTGKTTT
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCCHHH
VAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGAALRQLPLTDAQKKRIPEDASTL
HHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHH
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPPHGRVIFLGDRDQ
HHHHCCCCCHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCHH
LASVEAGAVLGDICAYVNAGFTAERARQLSRLTGSAIPAGAGTQAASLRDSLCLLQKSYR
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHC
FGSDSGIGKLAAAINCGDRSAIQAVFQQGFSDIEKRTLQSSDDYAGMLDEALAGYGRYLR
CCCCCCHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LLHEKATPEAILQAFNEYQLLCALREGPFGVRGLNDRIEQAMVQQRKIQRHPHSRWYEGR
HHHHCCCHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
PVMIARNDSALGLFNGDIGIALDRGQGLRVWFVMPDGTIKSVQPSRLPEHDTTWAMTVHK
EEEEEECCCEEEEEECCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEC
SQGSEFDHAALILPSQRSPVVTRELVYTAVTRARRRLSLYADERILASAIVTRTERRSGL
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
ATLFDEVSRTG
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]