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The map label for this gene is uxaA [H]

Identifier: 194735589

GI number: 194735589

Start: 785621

End: 786787

Strand: Direct

Name: uxaA [H]

Synonym: SeSA_A0810

Alternate gene names: 194735589

Gene position: 785621-786787 (Clockwise)

Preceding gene: 194736813

Following gene: 194735971

Centisome position: 16.68

GC content: 52.61

Gene sequence:

>1167_bases
ATGAGCAATGAGACTTTTTTGGGTTTCCGCCGCCCTGACGGCCGTTTTGGCATCCGTAATTATGTACTGATTTTACCTAC
CAGCGTTTGTGCGAATAAAGTTGCCCAGGATATTGCCCGGCAGGTAAAAGGCGCGACATGGGTGAATAACGATTTTGGCT
GCTGCCAGGTGGCAGGCGATGCGCGTCTGACGGAAAAGACATTGATTAATGTGGCGAATAATCCCAACGTCGGCGCTATT
GTGGTTGTGGGCTTAGGCTGTGAAGGCGCGGAGCCGCTGCGCATCGCAGAAGAGATTACCGCATTTGGCAAACCGACTTC
CTGCATTACCATTCAGGAAGAGGGCGGCACGCTTAAATGTCAGGCCAGGGGGATTTCGCTGGCCCGCGACTATGCACAAC
AACTCTCCATGCAAAAACCGCAGCAAGCACCGGTTAGCGAGCTGCTGCTGGCGATGGAGTGCGGCGGGTCAGATACGACA
TCGGGGCTGGCGTCTAACCCTTCCTGCGGGGTCGCCTCGGATAAGCTGATACGCTGCGGCGGAAGCTCAATTCTTTCTGA
AACGACGGAATTTATTGGCGCCGAGCATGTGATGGCGAAACGTGCGGTGACGCCGGAGGTTGGTCAACAGCTCATTGATT
TAGTGGTCGGCTGCGAGGCGCGAGCAAAAGCGCTGGGCGAGGATATTCGCGGGGGACAGCCGACGCCGGGCAATATTAAA
GGCGGGTTGACTACCATTGAAGAAAAATCGTTAGGCTGTATGCATAAAGCGGGTCATGCGCCGCTACAGGGTGTACTGGA
ATATGCCGATAGCCCAACGCATCCGGGCCTGTGGATTATGGATACCCCGGGGCAGGATATTGAATCTATTTCCGGCATGG
TGGCGGGTGGAGCGCAGATCGTTATTTTTACTACCGGTCGCGGAACGCCTGCCGGTAACCCAATAGCGCCGGTAATAAAA
ATTACGGGTAATAAAGCAACGTGGGAAATGATGCAGGACAATATTGATATTGATGTGTCCGCCATTATGTCTGGCGAGGC
TTCTATTACGCAAATGGGCGAGGAAATTTATCAGGAAATTTTACGCGTCGCGAATGGGAAAACGACTAAATCAGAAGATT
TAGGTCATAACGAATTCTCTATTTATAAGATCGCGCCGACGTTCTGA

Upstream 100 bases:

>100_bases
ACTCAGGAAATAAAAAGTGGCGACTATGTGCACGTCCACAATGTGGAAAGCGAACGCGGACGTGGTGACTGGAAATAATA
TAAAACAAGGAAAAATGATT

Downstream 100 bases:

>100_bases
TACCAAATCGGGCAGCACCAGCTGTCCGGTTATCTCCTGGGAATAAGCTATGAAAATTAAAAAAACACTGGAACGTTTTC
CTGGTGGTATGATGGTTGTA

Product: UxaA family hydrolase

Products: NA

Alternate protein names: Altronic acid hydratase [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MSNETFLGFRRPDGRFGIRNYVLILPTSVCANKVAQDIARQVKGATWVNNDFGCCQVAGDARLTEKTLINVANNPNVGAI
VVVGLGCEGAEPLRIAEEITAFGKPTSCITIQEEGGTLKCQARGISLARDYAQQLSMQKPQQAPVSELLLAMECGGSDTT
SGLASNPSCGVASDKLIRCGGSSILSETTEFIGAEHVMAKRAVTPEVGQQLIDLVVGCEARAKALGEDIRGGQPTPGNIK
GGLTTIEEKSLGCMHKAGHAPLQGVLEYADSPTHPGLWIMDTPGQDIESISGMVAGGAQIVIFTTGRGTPAGNPIAPVIK
ITGNKATWEMMQDNIDIDVSAIMSGEASITQMGEEIYQEILRVANGKTTKSEDLGHNEFSIYKIAPTF

Sequences:

>Translated_388_residues
MSNETFLGFRRPDGRFGIRNYVLILPTSVCANKVAQDIARQVKGATWVNNDFGCCQVAGDARLTEKTLINVANNPNVGAI
VVVGLGCEGAEPLRIAEEITAFGKPTSCITIQEEGGTLKCQARGISLARDYAQQLSMQKPQQAPVSELLLAMECGGSDTT
SGLASNPSCGVASDKLIRCGGSSILSETTEFIGAEHVMAKRAVTPEVGQQLIDLVVGCEARAKALGEDIRGGQPTPGNIK
GGLTTIEEKSLGCMHKAGHAPLQGVLEYADSPTHPGLWIMDTPGQDIESISGMVAGGAQIVIFTTGRGTPAGNPIAPVIK
ITGNKATWEMMQDNIDIDVSAIMSGEASITQMGEEIYQEILRVANGKTTKSEDLGHNEFSIYKIAPTF
>Mature_387_residues
SNETFLGFRRPDGRFGIRNYVLILPTSVCANKVAQDIARQVKGATWVNNDFGCCQVAGDARLTEKTLINVANNPNVGAIV
VVGLGCEGAEPLRIAEEITAFGKPTSCITIQEEGGTLKCQARGISLARDYAQQLSMQKPQQAPVSELLLAMECGGSDTTS
GLASNPSCGVASDKLIRCGGSSILSETTEFIGAEHVMAKRAVTPEVGQQLIDLVVGCEARAKALGEDIRGGQPTPGNIKG
GLTTIEEKSLGCMHKAGHAPLQGVLEYADSPTHPGLWIMDTPGQDIESISGMVAGGAQIVIFTTGRGTPAGNPIAPVIKI
TGNKATWEMMQDNIDIDVSAIMSGEASITQMGEEIYQEILRVANGKTTKSEDLGHNEFSIYKIAPTF

Specific function: D-galactarate metabolism; first step. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789516, Length=404, Percent_Identity=33.9108910891089, Blast_Score=211, Evalue=9e-56,
Organism=Escherichia coli, GI1789475, Length=391, Percent_Identity=33.7595907928389, Blast_Score=204, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.7 [H]

Molecular weight: Translated: 40951; Mature: 40820

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNETFLGFRRPDGRFGIRNYVLILPTSVCANKVAQDIARQVKGATWVNNDFGCCQVAGD
CCCCCEEEEECCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHCCCEEECCCCCEEEECCC
ARLTEKTLINVANNPNVGAIVVVGLGCEGAEPLRIAEEITAFGKPTSCITIQEEGGTLKC
CCCCHHHEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEECCCEEEE
QARGISLARDYAQQLSMQKPQQAPVSELLLAMECGGSDTTSGLASNPSCGVASDKLIRCG
EECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECC
GSSILSETTEFIGAEHVMAKRAVTPEVGQQLIDLVVGCEARAKALGEDIRGGQPTPGNIK
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCC
GGLTTIEEKSLGCMHKAGHAPLQGVLEYADSPTHPGLWIMDTPGQDIESISGMVAGGAQI
CCCEEEHHHHCCHHHHCCCCHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHEECCCCEE
VIFTTGRGTPAGNPIAPVIKITGNKATWEMMQDNIDIDVSAIMSGEASITQMGEEIYQEI
EEEECCCCCCCCCCCCEEEEEECCCCEEHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHH
LRVANGKTTKSEDLGHNEFSIYKIAPTF
HHHHCCCCCCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure 
SNETFLGFRRPDGRFGIRNYVLILPTSVCANKVAQDIARQVKGATWVNNDFGCCQVAGD
CCCCEEEEECCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHCCCEEECCCCCEEEECCC
ARLTEKTLINVANNPNVGAIVVVGLGCEGAEPLRIAEEITAFGKPTSCITIQEEGGTLKC
CCCCHHHEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEECCCEEEE
QARGISLARDYAQQLSMQKPQQAPVSELLLAMECGGSDTTSGLASNPSCGVASDKLIRCG
EECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECC
GSSILSETTEFIGAEHVMAKRAVTPEVGQQLIDLVVGCEARAKALGEDIRGGQPTPGNIK
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCC
GGLTTIEEKSLGCMHKAGHAPLQGVLEYADSPTHPGLWIMDTPGQDIESISGMVAGGAQI
CCCEEEHHHHCCHHHHCCCCHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHEECCCCEE
VIFTTGRGTPAGNPIAPVIKITGNKATWEMMQDNIDIDVSAIMSGEASITQMGEEIYQEI
EEEECCCCCCCCCCCCEEEEEECCCCEEHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHH
LRVANGKTTKSEDLGHNEFSIYKIAPTF
HHHHCCCCCCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]