| Definition | Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633 chromosome, complete genome. |
|---|---|
| Accession | NC_011094 |
| Length | 4,709,075 |
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The map label for this gene is helD [H]
Identifier: 194735557
GI number: 194735557
Start: 1125319
End: 1127373
Strand: Direct
Name: helD [H]
Synonym: SeSA_A1138
Alternate gene names: 194735557
Gene position: 1125319-1127373 (Clockwise)
Preceding gene: 194734303
Following gene: 194736723
Centisome position: 23.9
GC content: 55.18
Gene sequence:
>2055_bases ATGGAACTGAAAGCTACTTCTCTTGGAAAACGTCTGGCGCAACACCCGTATGATCGTGCCGTGATCCTCAACGCTGGGGT GAAAGTGTCTGGCGACAGGCATGAATATCTTATTCCATTCAATCAGTTATTGGCGATTCACTGTAAGCGTGGGCTGGTAT GGGGCGAGCTGGAGTTTGTCCTGCCGGAGGATAAAGTCGTGCGTTTGCATGGTACTGAGTGGTCGGAAACCCAGCAATTC CATCGCTATCTGGACGCGCACTGGCGTCGCTGGAGCCAGGAGATGAGTGATGTCGCCGCGCAGGCATTGCAGGAGCAATG GGAGCGTATTAGTGAGCGAACGGGCGAAAACCAATGGCTTACCCGTGAACGCGTTCGGGGGCTGGAACACGAAATTCGCC AGACGTTTGCCGCCTTGCCGCTGCCGGTCTCACGTCTGGAGGAGTTTGCTCACTGTCGCGAGATATGGCGTAAGTGTCTG GCCTGGTTACAGGATAGCGAGGGAAGTCGGCAGCAGCATAATCAGGCGTATGCTGATGCCATGCTGGAAGCGCATGCCGA CTTTTTTACGCAGATAGAATCTTCTCCGCTTAATCCTTCCCAGGCCAGGGCGGTGGTTAACGGCGAATCATCGTTACTGG TACTGGCGGGCGCGGGAAGCGGTAAGACCTCGGTGCTGGTGGCGCGCGCGGGTTGGCTGTTGGCGCGCGGACAAGCAGAT GCGGGGCAAATTCTTTTACTGGCGTTTGGTCGCAAGGCGGCAGAGGAGATGGATGAGCGTATCCGCGAGCGCTTACATAC GGAAGAGATTACTGCCCGTACGTTCCATTCGCTGGCGCTGTATATTATTCAGCAAGGCAGTAAAAAAGCGCCGGTTGTCA GTAAGCTGGAAAGTGACGCCACCGCGCGGCATCAGCTATTTCTGCGCACCTGGCGTCAGCAGTGTAGCGAGAAAAAAGCG CAGGCCAAAGGCTGGCGTCAGTGGCTGGAAGAGGAGATGCAGTGGGTAGTGCCGGAAGGTAATTTCTGGGACGATGAGAC ATTGCAGCGGCGTCTGGCCCCTCGCCTGGATCGTTGGGTCAGCTTGATGCGTATGCACGGCGGCGCGCAGGCAGAAATGA TCGCTGGCGCGCCAGAGGAGTGCCGCGAGCTGTTTGGCAAACGCATTAAGCTGATGGCGCCGCTGCTGAAGGCCTGGAAA AGCGCGTTGAAAGCGGAAAATGCCGTTGATTTCTCCGGTCTGATCCATCAGGCAATGGTGATCCTCGAAAAAGGGCGTTT TATCAGCCCGTGGAAGCATATTCTGGTCGATGAATTTCAGGATATTTCCCCGCAACGGGCGGCGCTGTTAGAAGCACTGC GCAAGCAGAATAGCCAGACTACGCTGTTTGCCGTGGGCGATGACTGGCAGGCGATTTACCGTTTTAGCGGGGCGCAGCTC TCCTTAACGACGGCGTTTCATCAGATGTTCGGCGAGGGCGAGCATTGCCACCTGGACACCACGTACCGTTTTAACAGTCG GATTGGCGATATTGCCAATCGCTTTGTACAGCAGAATCCGCACCAGCTTAAAAAACCGTTAAATAGTCTGACCCCAGGCG ATAAAAAAGCGGTGACGTTATTAGATGAAAGCCAGTTGGACGCGTTACTGGATAAATTATCCGGCTATGCGAAGGAAGAT GAACGTATCCTGGTGCTGGCGCGCTATCATCATCTGAAACCCGCGAGTCTACAAAAAGCGGCGACTCGCTGGCCGAAGTT ACAGATAGACTTCATGACTATCCATGCCAGCAAAGGCCAACAGGCCGATTACGTGATTCTTGTCGGATTGCAGGAGGGTA ACGACGGTTTCCCCGCCCCGGCGCGAGAATCCATTATGGAAAGTGCGCTTCTTCCTCAGGTTGAGGATTTTCCGGACGCT GAAGAGCGGCGTTTGTTATATGTGGCGTTGACGCGCGCGCGTGCGCGGGTCTGGCTGCTTTTTAATAAAGATAATCCCTC GCGCTTTGTGGAGGCGCTTAAACAGCTGGATGTGCCGGTGGCGAGGAAGCCCTAA
Upstream 100 bases:
>100_bases TCTATCACTGCGGGCAATTGTAACGTTTTTTTAGACTGGAGCACGTTTTCTCTGGCGGTTACACTGATAAGCACATCTTT ACGTCTGGATTCGCTGAGTC
Downstream 100 bases:
>100_bases AGCGCGGGCGGTACAGCATCCCGCCCGCGTAGCGGTTATTTCAGGCCGCGTAGCGGTTATTTCAGGCGCTCGGCCAGATA ACGCGCATAATCCGGAATAA
Product: DNA helicase IV
Products: NA
Alternate protein names: 75 kDa helicase [H]
Number of amino acids: Translated: 684; Mature: 684
Protein sequence:
>684_residues MELKATSLGKRLAQHPYDRAVILNAGVKVSGDRHEYLIPFNQLLAIHCKRGLVWGELEFVLPEDKVVRLHGTEWSETQQF HRYLDAHWRRWSQEMSDVAAQALQEQWERISERTGENQWLTRERVRGLEHEIRQTFAALPLPVSRLEEFAHCREIWRKCL AWLQDSEGSRQQHNQAYADAMLEAHADFFTQIESSPLNPSQARAVVNGESSLLVLAGAGSGKTSVLVARAGWLLARGQAD AGQILLLAFGRKAAEEMDERIRERLHTEEITARTFHSLALYIIQQGSKKAPVVSKLESDATARHQLFLRTWRQQCSEKKA QAKGWRQWLEEEMQWVVPEGNFWDDETLQRRLAPRLDRWVSLMRMHGGAQAEMIAGAPEECRELFGKRIKLMAPLLKAWK SALKAENAVDFSGLIHQAMVILEKGRFISPWKHILVDEFQDISPQRAALLEALRKQNSQTTLFAVGDDWQAIYRFSGAQL SLTTAFHQMFGEGEHCHLDTTYRFNSRIGDIANRFVQQNPHQLKKPLNSLTPGDKKAVTLLDESQLDALLDKLSGYAKED ERILVLARYHHLKPASLQKAATRWPKLQIDFMTIHASKGQQADYVILVGLQEGNDGFPAPARESIMESALLPQVEDFPDA EERRLLYVALTRARARVWLLFNKDNPSRFVEALKQLDVPVARKP
Sequences:
>Translated_684_residues MELKATSLGKRLAQHPYDRAVILNAGVKVSGDRHEYLIPFNQLLAIHCKRGLVWGELEFVLPEDKVVRLHGTEWSETQQF HRYLDAHWRRWSQEMSDVAAQALQEQWERISERTGENQWLTRERVRGLEHEIRQTFAALPLPVSRLEEFAHCREIWRKCL AWLQDSEGSRQQHNQAYADAMLEAHADFFTQIESSPLNPSQARAVVNGESSLLVLAGAGSGKTSVLVARAGWLLARGQAD AGQILLLAFGRKAAEEMDERIRERLHTEEITARTFHSLALYIIQQGSKKAPVVSKLESDATARHQLFLRTWRQQCSEKKA QAKGWRQWLEEEMQWVVPEGNFWDDETLQRRLAPRLDRWVSLMRMHGGAQAEMIAGAPEECRELFGKRIKLMAPLLKAWK SALKAENAVDFSGLIHQAMVILEKGRFISPWKHILVDEFQDISPQRAALLEALRKQNSQTTLFAVGDDWQAIYRFSGAQL SLTTAFHQMFGEGEHCHLDTTYRFNSRIGDIANRFVQQNPHQLKKPLNSLTPGDKKAVTLLDESQLDALLDKLSGYAKED ERILVLARYHHLKPASLQKAATRWPKLQIDFMTIHASKGQQADYVILVGLQEGNDGFPAPARESIMESALLPQVEDFPDA EERRLLYVALTRARARVWLLFNKDNPSRFVEALKQLDVPVARKP >Mature_684_residues MELKATSLGKRLAQHPYDRAVILNAGVKVSGDRHEYLIPFNQLLAIHCKRGLVWGELEFVLPEDKVVRLHGTEWSETQQF HRYLDAHWRRWSQEMSDVAAQALQEQWERISERTGENQWLTRERVRGLEHEIRQTFAALPLPVSRLEEFAHCREIWRKCL AWLQDSEGSRQQHNQAYADAMLEAHADFFTQIESSPLNPSQARAVVNGESSLLVLAGAGSGKTSVLVARAGWLLARGQAD AGQILLLAFGRKAAEEMDERIRERLHTEEITARTFHSLALYIIQQGSKKAPVVSKLESDATARHQLFLRTWRQQCSEKKA QAKGWRQWLEEEMQWVVPEGNFWDDETLQRRLAPRLDRWVSLMRMHGGAQAEMIAGAPEECRELFGKRIKLMAPLLKAWK SALKAENAVDFSGLIHQAMVILEKGRFISPWKHILVDEFQDISPQRAALLEALRKQNSQTTLFAVGDDWQAIYRFSGAQL SLTTAFHQMFGEGEHCHLDTTYRFNSRIGDIANRFVQQNPHQLKKPLNSLTPGDKKAVTLLDESQLDALLDKLSGYAKED ERILVLARYHHLKPASLQKAATRWPKLQIDFMTIHASKGQQADYVILVGLQEGNDGFPAPARESIMESALLPQVEDFPDA EERRLLYVALTRARARVWLLFNKDNPSRFVEALKQLDVPVARKP
Specific function: Helicase IV catalyzes the unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand in a reaction that is dependent upon the hydrolysis of ATP [H]
COG id: COG0210
COG function: function code L; Superfamily I DNA and RNA helicases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]
Homologues:
Organism=Escherichia coli, GI1787196, Length=684, Percent_Identity=84.2105263157895, Blast_Score=1200, Evalue=0.0, Organism=Escherichia coli, GI48994965, Length=341, Percent_Identity=29.9120234604106, Blast_Score=100, Evalue=4e-22, Organism=Escherichia coli, GI2367296, Length=339, Percent_Identity=28.023598820059, Blast_Score=94, Evalue=4e-20,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000212 - InterPro: IPR014016 - InterPro: IPR022161 - InterPro: IPR003661 [H]
Pfam domain/function: PF12462 Nucleolin_N; PF00580 UvrD-helicase [H]
EC number: =3.6.4.12 [H]
Molecular weight: Translated: 78203; Mature: 78203
Theoretical pI: Translated: 8.19; Mature: 8.19
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MELKATSLGKRLAQHPYDRAVILNAGVKVSGDRHEYLIPFNQLLAIHCKRGLVWGELEFV CCCCHHHHHHHHHHCCCCCEEEEECCEEECCCCCEEECCHHHHHHHHHHCCCEEEEEEEE LPEDKVVRLHGTEWSETQQFHRYLDAHWRRWSQEMSDVAAQALQEQWERISERTGENQWL CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH TRERVRGLEHEIRQTFAALPLPVSRLEEFAHCREIWRKCLAWLQDSEGSRQQHNQAYADA HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH MLEAHADFFTQIESSPLNPSQARAVVNGESSLLVLAGAGSGKTSVLVARAGWLLARGQAD HHHHHHHHHHHHCCCCCCHHHCEEEEECCCCEEEEEECCCCCCEEEEEECCEEEECCCCC AGQILLLAFGRKAAEEMDERIRERLHTEEITARTFHSLALYIIQQGSKKAPVVSKLESDA CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCH TARHQLFLRTWRQQCSEKKAQAKGWRQWLEEEMQWVVPEGNFWDDETLQRRLAPRLDRWV HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHH SLMRMHGGAQAEMIAGAPEECRELFGKRIKLMAPLLKAWKSALKAENAVDFSGLIHQAMV HHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH ILEKGRFISPWKHILVDEFQDISPQRAALLEALRKQNSQTTLFAVGDDWQAIYRFSGAQL HHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHCCCCEE SLTTAFHQMFGEGEHCHLDTTYRFNSRIGDIANRFVQQNPHQLKKPLNSLTPGDKKAVTL HHHHHHHHHHCCCCEEEEECEEEHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEE LDESQLDALLDKLSGYAKEDERILVLARYHHLKPASLQKAATRWPKLQIDFMTIHASKGQ ECHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCEEEEEEEEECCCCC QADYVILVGLQEGNDGFPAPARESIMESALLPQVEDFPDAEERRLLYVALTRARARVWLL CCCEEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHCEEEEEEEHHCCEEEEEE FNKDNPSRFVEALKQLDVPVARKP EECCCHHHHHHHHHHCCCCCCCCC >Mature Secondary Structure MELKATSLGKRLAQHPYDRAVILNAGVKVSGDRHEYLIPFNQLLAIHCKRGLVWGELEFV CCCCHHHHHHHHHHCCCCCEEEEECCEEECCCCCEEECCHHHHHHHHHHCCCEEEEEEEE LPEDKVVRLHGTEWSETQQFHRYLDAHWRRWSQEMSDVAAQALQEQWERISERTGENQWL CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH TRERVRGLEHEIRQTFAALPLPVSRLEEFAHCREIWRKCLAWLQDSEGSRQQHNQAYADA HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH MLEAHADFFTQIESSPLNPSQARAVVNGESSLLVLAGAGSGKTSVLVARAGWLLARGQAD HHHHHHHHHHHHCCCCCCHHHCEEEEECCCCEEEEEECCCCCCEEEEEECCEEEECCCCC AGQILLLAFGRKAAEEMDERIRERLHTEEITARTFHSLALYIIQQGSKKAPVVSKLESDA CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCH TARHQLFLRTWRQQCSEKKAQAKGWRQWLEEEMQWVVPEGNFWDDETLQRRLAPRLDRWV HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHH SLMRMHGGAQAEMIAGAPEECRELFGKRIKLMAPLLKAWKSALKAENAVDFSGLIHQAMV HHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH ILEKGRFISPWKHILVDEFQDISPQRAALLEALRKQNSQTTLFAVGDDWQAIYRFSGAQL HHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHCCCCEE SLTTAFHQMFGEGEHCHLDTTYRFNSRIGDIANRFVQQNPHQLKKPLNSLTPGDKKAVTL HHHHHHHHHHCCCCEEEEECEEEHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEE LDESQLDALLDKLSGYAKEDERILVLARYHHLKPASLQKAATRWPKLQIDFMTIHASKGQ ECHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCEEEEEEEEECCCCC QADYVILVGLQEGNDGFPAPARESIMESALLPQVEDFPDAEERRLLYVALTRARARVWLL CCCEEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHCEEEEEEEHHCCEEEEEE FNKDNPSRFVEALKQLDVPVARKP EECCCHHHHHHHHHHCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2542273; 8905232; 9278503 [H]