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The map label for this gene is cutC [H]

Identifier: 194735535

GI number: 194735535

Start: 1978905

End: 1979651

Strand: Reverse

Name: cutC [H]

Synonym: SeSA_A2061

Alternate gene names: 194735535

Gene position: 1979651-1978905 (Counterclockwise)

Preceding gene: 194735036

Following gene: 194735477

Centisome position: 42.04

GC content: 54.35

Gene sequence:

>747_bases
ATGGCGTTACTTGAGATCTGTTGTTACAGCATGGAATGCGCGCTCACCGCGCAGCGAAACGGCGCGGATCGTATCGAACT
GTGCGCCGCGCCGAAAGAAGGCGGGCTTACGCCTTCGCTGGGCGTCTTACGCAGCGTGCGCGAGCATATTACGATTCCCG
TACATCCGATTATTCGTCCTCGTGGCGGGGATTTTTACTACACTGACGGCGAATTTGCCGCCATGCTGGAAGATATCCGC
CTCGTCAGAGAGTTGGGGTTTCCTGGGCTGGTTACTGGCGTGTTGACCGTTGATGGGGATGTCGATATGTCGCGAATGGA
AAAAATAATGGCGGCGGCCGGACCGCTGGCAGTGACATTCCACCGCGCCTTCGATATGTGCGCTAATCCCTTCAATGCGC
TAAAGAATCTGGCTGACGCAGGCGTATCAAGAGTACTGACTTCCGGGCAAAAAGCCGATGCGGCGCAAGGTTTATCAATA
ATTATGGAACTTATTGCCCAGGGGGATGCTCCAATCATTATGGCTGGTGCGGGGGTTCGTGCAAATAACCTGCAGAATTT
CCTCGATGCCGGAGTACGGGAAGTACACAGTTCCGCCGGAGTCTTACTGCCTTCGCCGATGCGCTATCGCAATCAGGGGT
TATCGATGTCTGCCGATATACAGGCGGACGAGTATTCTCGCTATAGGGTAGAGGGTGCGGCGGTCGCTGAAATGAAAGGA
ATCATTGTTCGCCATCAGGCCAAATGA

Upstream 100 bases:

>100_bases
GTGACCGATGGCCGCATCACGGTAAAATTTCATCCATGGTCGATTGAAGCGATTGTCGCCAGCGAACAGGCGGCCCATTA
ACCTGCCGAGCGGAGTGAAT

Downstream 100 bases:

>100_bases
TTTTTACCGTTGCATCATGTCGCCCAATATGATGCTTGCTCGTACCAGGCCCCTGCCAATTCAACAGGGGCCTTTTTTTC
TCCTTCATATTTCAAGCCGC

Product: copper homeostasis protein CutC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MALLEICCYSMECALTAQRNGADRIELCAAPKEGGLTPSLGVLRSVREHITIPVHPIIRPRGGDFYYTDGEFAAMLEDIR
LVRELGFPGLVTGVLTVDGDVDMSRMEKIMAAAGPLAVTFHRAFDMCANPFNALKNLADAGVSRVLTSGQKADAAQGLSI
IMELIAQGDAPIIMAGAGVRANNLQNFLDAGVREVHSSAGVLLPSPMRYRNQGLSMSADIQADEYSRYRVEGAAVAEMKG
IIVRHQAK

Sequences:

>Translated_248_residues
MALLEICCYSMECALTAQRNGADRIELCAAPKEGGLTPSLGVLRSVREHITIPVHPIIRPRGGDFYYTDGEFAAMLEDIR
LVRELGFPGLVTGVLTVDGDVDMSRMEKIMAAAGPLAVTFHRAFDMCANPFNALKNLADAGVSRVLTSGQKADAAQGLSI
IMELIAQGDAPIIMAGAGVRANNLQNFLDAGVREVHSSAGVLLPSPMRYRNQGLSMSADIQADEYSRYRVEGAAVAEMKG
IIVRHQAK
>Mature_247_residues
ALLEICCYSMECALTAQRNGADRIELCAAPKEGGLTPSLGVLRSVREHITIPVHPIIRPRGGDFYYTDGEFAAMLEDIRL
VRELGFPGLVTGVLTVDGDVDMSRMEKIMAAAGPLAVTFHRAFDMCANPFNALKNLADAGVSRVLTSGQKADAAQGLSII
MELIAQGDAPIIMAGAGVRANNLQNFLDAGVREVHSSAGVLLPSPMRYRNQGLSMSADIQADEYSRYRVEGAAVAEMKGI
IVRHQAK

Specific function: Involved in copper homeostasis [H]

COG id: COG3142

COG function: function code P; Uncharacterized protein involved in copper resistance

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutC family [H]

Homologues:

Organism=Homo sapiens, GI148596990, Length=226, Percent_Identity=47.787610619469, Blast_Score=201, Evalue=6e-52,
Organism=Escherichia coli, GI87081995, Length=248, Percent_Identity=83.4677419354839, Blast_Score=424, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI17556905, Length=201, Percent_Identity=38.8059701492537, Blast_Score=135, Evalue=1e-32,
Organism=Drosophila melanogaster, GI21355415, Length=201, Percent_Identity=40.7960199004975, Blast_Score=148, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005627 [H]

Pfam domain/function: PF03932 CutC [H]

EC number: NA

Molecular weight: Translated: 26605; Mature: 26474

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLEICCYSMECALTAQRNGADRIELCAAPKEGGLTPSLGVLRSVREHITIPVHPIIRP
CHHHHHHHHHHHHEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEECC
RGGDFYYTDGEFAAMLEDIRLVRELGFPGLVTGVLTVDGDVDMSRMEKIMAAAGPLAVTF
CCCCEEEECCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCHHHHH
HRAFDMCANPFNALKNLADAGVSRVLTSGQKADAAQGLSIIMELIAQGDAPIIMAGAGVR
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCC
ANNLQNFLDAGVREVHSSAGVLLPSPMRYRNQGLSMSADIQADEYSRYRVEGAAVAEMKG
HHHHHHHHHHHHHHHHHCCCEECCCCHHHHHCCCCEECCCCCCCCHHEEECCHHHHHHHC
IIVRHQAK
CCEEECCC
>Mature Secondary Structure 
ALLEICCYSMECALTAQRNGADRIELCAAPKEGGLTPSLGVLRSVREHITIPVHPIIRP
HHHHHHHHHHHHEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEECC
RGGDFYYTDGEFAAMLEDIRLVRELGFPGLVTGVLTVDGDVDMSRMEKIMAAAGPLAVTF
CCCCEEEECCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCHHHHH
HRAFDMCANPFNALKNLADAGVSRVLTSGQKADAAQGLSIIMELIAQGDAPIIMAGAGVR
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCC
ANNLQNFLDAGVREVHSSAGVLLPSPMRYRNQGLSMSADIQADEYSRYRVEGAAVAEMKG
HHHHHHHHHHHHHHHHHCCCEECCCCHHHHHCCCCEECCCCCCCCHHEEECCHHHHHHHC
IIVRHQAK
CCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]