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The map label for this gene is cysC

Identifier: 194735437

GI number: 194735437

Start: 2977688

End: 2978293

Strand: Reverse

Name: cysC

Synonym: SeSA_A3084

Alternate gene names: 194735437

Gene position: 2978293-2977688 (Counterclockwise)

Preceding gene: 194737140

Following gene: 194736877

Centisome position: 63.25

GC content: 54.79

Gene sequence:

>606_bases
ATGGCGCTGCATGATGAGAACGTGGTCTGGCACTCTCATCCCGTTACTGTCGCCGCCCGTGAACAGCTCCACGGCCACCG
TGGCGTGGTGCTGTGGTTTACCGGACTCTCCGGTTCGGGAAAATCAACGGTGGCCGGCGCGCTGGAAGAGGCGTTACATC
AGCGTGGCGTCAGTACCTACCTGTTGGATGGCGATAATGTGCGCCACGGTTTGTGCCGTGATTTAGGCTTTAGCGATGCC
GATCGCCAGGAGAATATCCGGCGGGTAGGCGAAGTGGCCAGTCTGATGGCGGACGCCGGCCTGATTGTTTTGACGGCATT
TATTTCTCCGCACCGCGCCGAGCGGCAACTGGTAAAAGAGCGCGTCGGCCACGATCGTTTTATCGAGATTTATGTCAATA
CGCCGCTGGCTATCTGTGAACAGCGCGATCCTAAAGGATTGTATAAAAAAGCGCGCGCGGGCGAGTTGCGTAACTTTACC
GGTATCGACGCCATTTACGAAGCGCCTGACTCGCCCCAGGTTCATCTTAATGGTGAACAATTAGTAACAAATTTGGTTTC
CCAATTATTAGACCTGCTGAGACGGCGCGATATTATCAGATCCTGA

Upstream 100 bases:

>100_bases
ACGCCGCCCGTGGAATACAGTGCGTTTGAGCTGGAGCTGAATGCGCTGGTACGCCGTCATTTTCCGCACTGGGACGCCCG
CGATTTGCTGGGAGATAAAC

Downstream 100 bases:

>100_bases
GACACCACCGGGCTTGTATGCCCGGTATGGTCAAGGTTACAGGATTTAATATGCGTAATAGCCATAACATTACTTTCACA
AGGTCAGACGCCTTCATGGT

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MALHDENVVWHSHPVTVAAREQLHGHRGVVLWFTGLSGSGKSTVAGALEEALHQRGVSTYLLDGDNVRHGLCRDLGFSDA
DRQENIRRVGEVASLMADAGLIVLTAFISPHRAERQLVKERVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFT
GIDAIYEAPDSPQVHLNGEQLVTNLVSQLLDLLRRRDIIRS

Sequences:

>Translated_201_residues
MALHDENVVWHSHPVTVAAREQLHGHRGVVLWFTGLSGSGKSTVAGALEEALHQRGVSTYLLDGDNVRHGLCRDLGFSDA
DRQENIRRVGEVASLMADAGLIVLTAFISPHRAERQLVKERVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFT
GIDAIYEAPDSPQVHLNGEQLVTNLVSQLLDLLRRRDIIRS
>Mature_200_residues
ALHDENVVWHSHPVTVAAREQLHGHRGVVLWFTGLSGSGKSTVAGALEEALHQRGVSTYLLDGDNVRHGLCRDLGFSDAD
RQENIRRVGEVASLMADAGLIVLTAFISPHRAERQLVKERVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFTG
IDAIYEAPDSPQVHLNGEQLVTNLVSQLLDLLRRRDIIRS

Specific function: Catalyzes the synthesis of activated sulfate

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family

Homologues:

Organism=Homo sapiens, GI46094058, Length=202, Percent_Identity=49.5049504950495, Blast_Score=196, Evalue=8e-51,
Organism=Homo sapiens, GI34447231, Length=201, Percent_Identity=50.2487562189055, Blast_Score=194, Evalue=6e-50,
Organism=Homo sapiens, GI62912492, Length=201, Percent_Identity=50.2487562189055, Blast_Score=194, Evalue=6e-50,
Organism=Escherichia coli, GI1789107, Length=201, Percent_Identity=85.5721393034826, Blast_Score=360, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17542422, Length=202, Percent_Identity=49.009900990099, Blast_Score=197, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6322852, Length=197, Percent_Identity=49.746192893401, Blast_Score=197, Evalue=7e-52,
Organism=Drosophila melanogaster, GI24667032, Length=201, Percent_Identity=45.771144278607, Blast_Score=173, Evalue=5e-44,
Organism=Drosophila melanogaster, GI24667028, Length=201, Percent_Identity=45.771144278607, Blast_Score=173, Evalue=5e-44,
Organism=Drosophila melanogaster, GI24667036, Length=201, Percent_Identity=45.771144278607, Blast_Score=173, Evalue=5e-44,
Organism=Drosophila melanogaster, GI24667040, Length=201, Percent_Identity=45.771144278607, Blast_Score=173, Evalue=5e-44,
Organism=Drosophila melanogaster, GI116007838, Length=201, Percent_Identity=45.771144278607, Blast_Score=173, Evalue=7e-44,
Organism=Drosophila melanogaster, GI24667044, Length=201, Percent_Identity=45.771144278607, Blast_Score=173, Evalue=7e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYSC_SALA4 (B5F414)

Other databases:

- EMBL:   CP001138
- RefSeq:   YP_002147830.1
- ProteinModelPortal:   B5F414
- SMR:   B5F414
- GeneID:   6796226
- GenomeReviews:   CP001138_GR
- KEGG:   sea:SeAg_B3058
- HOGENOM:   HBG309946
- OMA:   ITITAFV
- ProtClustDB:   PRK03846
- HAMAP:   MF_00065
- InterPro:   IPR002891
- TIGRFAMs:   TIGR00455

Pfam domain/function: PF01583 APS_kinase

EC number: =2.7.1.25

Molecular weight: Translated: 22386; Mature: 22255

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: ACT_SITE 109-109

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALHDENVVWHSHPVTVAAREQLHGHRGVVLWFTGLSGSGKSTVAGALEEALHQRGVSTY
CCCCCCCEEEECCCCEEHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEE
LLDGDNVRHGLCRDLGFSDADRQENIRRVGEVASLMADAGLIVLTAFISPHRAERQLVKE
EECCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHH
RVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFTGIDAIYEAPDSPQVHLNGEQ
HCCCCEEEEEEECCCHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHCCCCCCEEEECHHH
LVTNLVSQLLDLLRRRDIIRS
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALHDENVVWHSHPVTVAAREQLHGHRGVVLWFTGLSGSGKSTVAGALEEALHQRGVSTY
CCCCCCEEEECCCCEEHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEE
LLDGDNVRHGLCRDLGFSDADRQENIRRVGEVASLMADAGLIVLTAFISPHRAERQLVKE
EECCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHH
RVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFTGIDAIYEAPDSPQVHLNGEQ
HCCCCEEEEEEECCCHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHCCCCCCEEEECHHH
LVTNLVSQLLDLLRRRDIIRS
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA