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The map label for this gene is sohB [H]

Identifier: 194735219

GI number: 194735219

Start: 1790464

End: 1791510

Strand: Reverse

Name: sohB [H]

Synonym: SeSA_A1848

Alternate gene names: 194735219

Gene position: 1791510-1790464 (Counterclockwise)

Preceding gene: 194733904

Following gene: 194733931

Centisome position: 38.04

GC content: 53.68

Gene sequence:

>1047_bases
GTGGAATTGTTGTCTGAATATGGCTTATTTTTGGCAAAAATCGTCACTGTTGTGGTGGCCATTGCCGTCATTGTGTTGCT
GATCGTGAATGCTACGCAACGCAAACGTCAGCGCGGCGAGCTGCGCGTGACCAATTTGAGCGAGCAGTATCAGGAGATGA
AGGATGACCTTGCTGCGGCGTTGATGGATGGCCATCAGCAAAAACTGTGGCATAAAGCGCAGAAAAAAAAGCATAAGCAG
GAGGCGAAAGCCGCCAAAGCGAAAGCGAAGCTGGGGGACATTGCGACATCGGACAAACCGCGCGTATGGGTGATAGATTT
CAAAGGCAGTATGGACGCTCACGAAGTTAATGCGTTACGCGAAGAGGTCACGGCGGTGCTGGCAGTGGCGAAACCCGGCG
ATCGGGCGGTTGTGCGTCTGGAAAGCCCCGGCGGCGTTGTGCATGGCTATGGCCTGGCGGCATCGCAATTGCAGCGCCTG
CGCGATAAAAATATTCCGCTGACCGTGACGGTGGATAAAGTCGCGGCAAGCGGAGGCTACATGATGGCCTGCGTGGCGGA
AAAAATTATTGCGGCGCCGTTCGCTATTGTGGGGTCAATTGGTGTTGTCGCGCAAATTCCGAACTTTAACCGCTTTCTCA
AAAGTAAAGACATTGATATTGAACTGCATACCGCAGGGCAGTACAAACGTACCCTGACATTGTTAGGCGAGAATACGGAA
GAAGGGCGGCAGAAGTTTCGTGAAGATCTCAACGAAACGCACCATCTGTTCAAAGAGTTTGTGCAGCGGATGCGTCCGGC
TCTGGACATTGAACAGGTCGCCACGGGCGAACACTGGTACGGTCAGCAGGCGCTGGAGAAAGGACTGGTTGATGAGATTA
ACACCAGCGATGAGGTTATCCTCGGCCTGATGGAAGGGCGTGAGGTGCTGAATGTGCGCTATATGCAGCGTAAAAAACTG
ATCGATCGTGTTACCGGCAGCGCGGCGGAAAGCGCGGATCGGCTGCTGCTGCGCTGGTGGCAGCGTGGACAAAAACCGTT
GATGTAA

Upstream 100 bases:

>100_bases
TACTTTTTCTTCCTCAACAGGCATACGGATGAAGAGAGACTGGCTTCGATGCCTGTTGTACACTGAGCGCAAGTCGCGTT
ATTTAATCAAGGTGGGAGTC

Downstream 100 bases:

>100_bases
ACCGCTATTGCCGGATGGCATTCAGCGCCATCCGGCATGGATTAATCCACCAGGTGATACTTCTCAGACAGCACATGCGC
CAGGTGTTTAAACATGTTAA

Product: putative periplasmic protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MELLSEYGLFLAKIVTVVVAIAVIVLLIVNATQRKRQRGELRVTNLSEQYQEMKDDLAAALMDGHQQKLWHKAQKKKHKQ
EAKAAKAKAKLGDIATSDKPRVWVIDFKGSMDAHEVNALREEVTAVLAVAKPGDRAVVRLESPGGVVHGYGLAASQLQRL
RDKNIPLTVTVDKVAASGGYMMACVAEKIIAAPFAIVGSIGVVAQIPNFNRFLKSKDIDIELHTAGQYKRTLTLLGENTE
EGRQKFREDLNETHHLFKEFVQRMRPALDIEQVATGEHWYGQQALEKGLVDEINTSDEVILGLMEGREVLNVRYMQRKKL
IDRVTGSAAESADRLLLRWWQRGQKPLM

Sequences:

>Translated_348_residues
MELLSEYGLFLAKIVTVVVAIAVIVLLIVNATQRKRQRGELRVTNLSEQYQEMKDDLAAALMDGHQQKLWHKAQKKKHKQ
EAKAAKAKAKLGDIATSDKPRVWVIDFKGSMDAHEVNALREEVTAVLAVAKPGDRAVVRLESPGGVVHGYGLAASQLQRL
RDKNIPLTVTVDKVAASGGYMMACVAEKIIAAPFAIVGSIGVVAQIPNFNRFLKSKDIDIELHTAGQYKRTLTLLGENTE
EGRQKFREDLNETHHLFKEFVQRMRPALDIEQVATGEHWYGQQALEKGLVDEINTSDEVILGLMEGREVLNVRYMQRKKL
IDRVTGSAAESADRLLLRWWQRGQKPLM
>Mature_348_residues
MELLSEYGLFLAKIVTVVVAIAVIVLLIVNATQRKRQRGELRVTNLSEQYQEMKDDLAAALMDGHQQKLWHKAQKKKHKQ
EAKAAKAKAKLGDIATSDKPRVWVIDFKGSMDAHEVNALREEVTAVLAVAKPGDRAVVRLESPGGVVHGYGLAASQLQRL
RDKNIPLTVTVDKVAASGGYMMACVAEKIIAAPFAIVGSIGVVAQIPNFNRFLKSKDIDIELHTAGQYKRTLTLLGENTE
EGRQKFREDLNETHHLFKEFVQRMRPALDIEQVATGEHWYGQQALEKGLVDEINTSDEVILGLMEGREVLNVRYMQRKKL
IDRVTGSAAESADRLLLRWWQRGQKPLM

Specific function: Multicopy suppressor of the htrA (degP) null phenotype. It is possibly a protease, not essential for bacterial viability [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=349, Percent_Identity=87.6790830945559, Blast_Score=573, Evalue=1e-165,
Organism=Escherichia coli, GI1788064, Length=178, Percent_Identity=28.0898876404494, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002142
- InterPro:   IPR013703 [H]

Pfam domain/function: PF01343 Peptidase_S49; PF08496 Peptidase_S49_N [H]

EC number: 3.4.21.-

Molecular weight: Translated: 38966; Mature: 38966

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLSEYGLFLAKIVTVVVAIAVIVLLIVNATQRKRQRGELRVTNLSEQYQEMKDDLAAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEECHHHHHHHHHHHHHHH
LMDGHQQKLWHKAQKKKHKQEAKAAKAKAKLGDIATSDKPRVWVIDFKGSMDAHEVNALR
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHH
EEVTAVLAVAKPGDRAVVRLESPGGVVHGYGLAASQLQRLRDKNIPLTVTVDKVAASGGY
HHHHHHHHEECCCCCEEEEECCCCCEEEECCHHHHHHHHHHHCCCCEEEEEHHHHCCCCH
MMACVAEKIIAAPFAIVGSIGVVAQIPNFNRFLKSKDIDIELHTAGQYKRTLTLLGENTE
HHHHHHHHHHHHHHHHHHCCHHEEECCCHHHHHHCCCCCEEEECCCCHHHHHHEECCCCH
EGRQKFREDLNETHHLFKEFVQRMRPALDIEQVATGEHWYGQQALEKGLVDEINTSDEVI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHCCCHHHCCCCHHHH
LGLMEGREVLNVRYMQRKKLIDRVTGSAAESADRLLLRWWQRGQKPLM
HHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MELLSEYGLFLAKIVTVVVAIAVIVLLIVNATQRKRQRGELRVTNLSEQYQEMKDDLAAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEECHHHHHHHHHHHHHHH
LMDGHQQKLWHKAQKKKHKQEAKAAKAKAKLGDIATSDKPRVWVIDFKGSMDAHEVNALR
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHH
EEVTAVLAVAKPGDRAVVRLESPGGVVHGYGLAASQLQRLRDKNIPLTVTVDKVAASGGY
HHHHHHHHEECCCCCEEEEECCCCCEEEECCHHHHHHHHHHHCCCCEEEEEHHHHCCCCH
MMACVAEKIIAAPFAIVGSIGVVAQIPNFNRFLKSKDIDIELHTAGQYKRTLTLLGENTE
HHHHHHHHHHHHHHHHHHCCHHEEECCCHHHHHHCCCCCEEEECCCCHHHHHHEECCCCH
EGRQKFREDLNETHHLFKEFVQRMRPALDIEQVATGEHWYGQQALEKGLVDEINTSDEVI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHCCCHHHCCCCHHHH
LGLMEGREVLNVRYMQRKKLIDRVTGSAAESADRLLLRWWQRGQKPLM
HHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1885549; 9097039; 9278503; 3029379 [H]