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The map label for this gene is rrmA [H]

Identifier: 194734932

GI number: 194734932

Start: 1910720

End: 1911529

Strand: Reverse

Name: rrmA [H]

Synonym: SeSA_A1979

Alternate gene names: 194734932

Gene position: 1911529-1910720 (Counterclockwise)

Preceding gene: 194735872

Following gene: 194734512

Centisome position: 40.59

GC content: 56.17

Gene sequence:

>810_bases
ATGTCGTTTACCTGTCCGCTTTGCCATCAGCCGCTTACGCAGATTAATAACAGCGTTATATGTCCACAGCGCCATCAGTT
TGATGTGGCGAAAGAGGGCTACATCAATCTGCTGCCGGTACAGCATAAACGTTCGCGCGATCCGGGCGACAGTGCCGAAA
TGATGCAGGCGCGGAGAGCGTTTCTTGATGCGGGCCATTATCAGCCGCTGCGCGATGCCGTGATTAACCTGTTGCGCGAG
CGGCTGGATCAGTCGGCCACGGCGATTCTGGATATTGGCTGCGGCGAGGGGTATTACACTCACGCTTTTGCCGAGGCGTT
GCCGGAAGTCACCACGTTTGGACTGGACGTTGCTAAAACGGCGATCAAAGCGGCGGCGAAACGCTATTCGCAGGTGAAGT
TTTGTGTGGCGTCAAGCCATCGACTGCCCTTTGCCGATGCGTCAATGGATGCGGTGATCAGAATCTATGCCCCGTGTAAG
GCGCAGGAATTGGCGCGTGTGGTGAAACCTGGTGGTTGGGTCGTTACCGCCACGCCGGGGCCGCATCATCTGATGGAACT
AAAAGGGCTCATTTATGATGAGGTGCGTTTACATGCGCCGTATACCGAGCAGCTCGACGGATTCACATTGCAGCAGAGTA
CCCGCCTTGCTTATCACATGCAGCTCACCGCCGAAGCGGCTGTAGCACTGTTGCAAATGACGCCATTTGCCTGGCGCGCC
AGGCCAGAAGTGTGGGAACAACTGGCCGCCAGCACCGGACTTAGCTGCCAGACGGATTTCAACCTTCATCTCTGGCAGCG
TAACCGTTAA

Upstream 100 bases:

>100_bases
TGCATGGCAGCCACGTTGCGGTTCCGGGCTCGTAAAGGATTTTCCCGGGGCGCAATTCGCGTTACACTTGCGCCCTTTAG
CGCCCCAGTCCGGAGTTGTC

Downstream 100 bases:

>100_bases
CCGTGAAAATGCGTCCAGAGGATCTGGACGCCAATTCCTATCAGTACGACCCCGCCGAGAATTTCAGCACGCTTACCCAG
CATTGGGCCGATAAAGCGAC

Product: 23S rRNA methyltransferase A

Products: NA

Alternate protein names: 23S rRNA m1G745 methyltransferase; rRNA (guanine-N(1)-)-methyltransferase [H]

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MSFTCPLCHQPLTQINNSVICPQRHQFDVAKEGYINLLPVQHKRSRDPGDSAEMMQARRAFLDAGHYQPLRDAVINLLRE
RLDQSATAILDIGCGEGYYTHAFAEALPEVTTFGLDVAKTAIKAAAKRYSQVKFCVASSHRLPFADASMDAVIRIYAPCK
AQELARVVKPGGWVVTATPGPHHLMELKGLIYDEVRLHAPYTEQLDGFTLQQSTRLAYHMQLTAEAAVALLQMTPFAWRA
RPEVWEQLAASTGLSCQTDFNLHLWQRNR

Sequences:

>Translated_269_residues
MSFTCPLCHQPLTQINNSVICPQRHQFDVAKEGYINLLPVQHKRSRDPGDSAEMMQARRAFLDAGHYQPLRDAVINLLRE
RLDQSATAILDIGCGEGYYTHAFAEALPEVTTFGLDVAKTAIKAAAKRYSQVKFCVASSHRLPFADASMDAVIRIYAPCK
AQELARVVKPGGWVVTATPGPHHLMELKGLIYDEVRLHAPYTEQLDGFTLQQSTRLAYHMQLTAEAAVALLQMTPFAWRA
RPEVWEQLAASTGLSCQTDFNLHLWQRNR
>Mature_268_residues
SFTCPLCHQPLTQINNSVICPQRHQFDVAKEGYINLLPVQHKRSRDPGDSAEMMQARRAFLDAGHYQPLRDAVINLLRER
LDQSATAILDIGCGEGYYTHAFAEALPEVTTFGLDVAKTAIKAAAKRYSQVKFCVASSHRLPFADASMDAVIRIYAPCKA
QELARVVKPGGWVVTATPGPHHLMELKGLIYDEVRLHAPYTEQLDGFTLQQSTRLAYHMQLTAEAAVALLQMTPFAWRAR
PEVWEQLAASTGLSCQTDFNLHLWQRNR

Specific function: Specifically methylates the guanosine in position 745 of 23S rRNA [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmA family [H]

Homologues:

Organism=Escherichia coli, GI1788125, Length=268, Percent_Identity=80.9701492537313, Blast_Score=473, Evalue=1e-135,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR016718 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.187 [H]

Molecular weight: Translated: 30147; Mature: 30016

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFTCPLCHQPLTQINNSVICPQRHQFDVAKEGYINLLPVQHKRSRDPGDSAEMMQARRA
CCCCCCHHHHHHHHHCCCEECCCCCCCCCCCCCCEEEEECCHHCCCCCCCHHHHHHHHHH
FLDAGHYQPLRDAVINLLRERLDQSATAILDIGCGEGYYTHAFAEALPEVTTFGLDVAKT
HHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AIKAAAKRYSQVKFCVASSHRLPFADASMDAVIRIYAPCKAQELARVVKPGGWVVTATPG
HHHHHHHHHHHHHHEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCEEEECCCC
PHHLMELKGLIYDEVRLHAPYTEQLDGFTLQQSTRLAYHMQLTAEAAVALLQMTPFAWRA
HHHHHHHHHHHHHHHEECCCCHHHCCCEEECCCCCEEEEEEHHHHHHHHHHHHCCCHHCC
RPEVWEQLAASTGLSCQTDFNLHLWQRNR
CHHHHHHHHHHCCCCEEECCEEEEEECCC
>Mature Secondary Structure 
SFTCPLCHQPLTQINNSVICPQRHQFDVAKEGYINLLPVQHKRSRDPGDSAEMMQARRA
CCCCCHHHHHHHHHCCCEECCCCCCCCCCCCCCEEEEECCHHCCCCCCCHHHHHHHHHH
FLDAGHYQPLRDAVINLLRERLDQSATAILDIGCGEGYYTHAFAEALPEVTTFGLDVAKT
HHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AIKAAAKRYSQVKFCVASSHRLPFADASMDAVIRIYAPCKAQELARVVKPGGWVVTATPG
HHHHHHHHHHHHHHEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCEEEECCCC
PHHLMELKGLIYDEVRLHAPYTEQLDGFTLQQSTRLAYHMQLTAEAAVALLQMTPFAWRA
HHHHHHHHHHHHHHHEECCCCHHHCCCEEECCCCCEEEEEEHHHHHHHHHHHHCCCHHCC
RPEVWEQLAASTGLSCQTDFNLHLWQRNR
CHHHHHHHHHHCCCCEEECCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7984109; 9097040; 9278503; 9440525 [H]