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The map label for this gene is iraD [H]

Identifier: 194734634

GI number: 194734634

Start: 3190587

End: 3190796

Strand: Reverse

Name: iraD [H]

Synonym: SeSA_A3306

Alternate gene names: 194734634

Gene position: 3190796-3190587 (Counterclockwise)

Preceding gene: 194734856

Following gene: 194736502

Centisome position: 67.76

GC content: 48.1

Gene sequence:

>210_bases
GTGAATGTGGGTGACAAACGGGTTCTCAACTGGTTTTGCCGTGAGCTTCGCGCTGCTATTTTACGTTATGAACCGAGCAT
CAACATGCTGAAAGTCAGTGTAAAAGATGCCCATCATCAGACGCTGGCGTTGTCTTTGGAAGCGATGTTACAGGATGAGT
CTGAACCGTTAAGACTGGAGATAGCCTACTCTAACGGTAGATGGCGCTAG

Upstream 100 bases:

>100_bases
GGTACGCCGCAAGTTAATGTGTTTATTCAACTCTTGCGCTGTGGCAGGTGGCGAGACATTACCGCCGCTGCTCACTCGGG
GTATGCCGGAATGGCACGAG

Downstream 100 bases:

>100_bases
TAATGCAGAAAAGAACGCCGGGCCGGGCGTTTTACATTACCCCAAAAGCAATAAAACGCAGCGAGCGAACCTGATAATCA
GGCAGGCAGTCCACCTTTCG

Product: DNA replication/recombination/repair protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 69; Mature: 69

Protein sequence:

>69_residues
MNVGDKRVLNWFCRELRAAILRYEPSINMLKVSVKDAHHQTLALSLEAMLQDESEPLRLEIAYSNGRWR

Sequences:

>Translated_69_residues
MNVGDKRVLNWFCRELRAAILRYEPSINMLKVSVKDAHHQTLALSLEAMLQDESEPLRLEIAYSNGRWR
>Mature_69_residues
MNVGDKRVLNWFCRELRAAILRYEPSINMLKVSVKDAHHQTLALSLEAMLQDESEPLRLEIAYSNGRWR

Specific function: Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of Rss

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GpW/Gp25 family. IraD subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082422, Length=68, Percent_Identity=47.0588235294118, Blast_Score=74, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015801
- InterPro:   IPR007048 [H]

Pfam domain/function: PF04965 GPW_gp25 [H]

EC number: NA

Molecular weight: Translated: 8084; Mature: 8084

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVGDKRVLNWFCRELRAAILRYEPSINMLKVSVKDAHHQTLALSLEAMLQDESEPLRLE
CCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEE
IAYSNGRWR
EEECCCCCC
>Mature Secondary Structure
MNVGDKRVLNWFCRELRAAILRYEPSINMLKVSVKDAHHQTLALSLEAMLQDESEPLRLE
CCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEE
IAYSNGRWR
EEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA