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The map label for this gene is arcB [H]

Identifier: 194734174

GI number: 194734174

Start: 3389625

End: 3391961

Strand: Reverse

Name: arcB [H]

Synonym: SeSA_A3521

Alternate gene names: 194734174

Gene position: 3391961-3389625 (Counterclockwise)

Preceding gene: 194734099

Following gene: 194735088

Centisome position: 72.03

GC content: 52.12

Gene sequence:

>2337_bases
ATGAAGCAAATTCGTATGCTGGCGCAATACTATGTCGACCTGATGATGAAATTGGGTCTGGTGCGCTTTTCCATGCTCCT
GGCGTTGGCATTGGTGGTGCTGGCGATTGTCGTGCAGATGGCGGTGACCATGGTGCTGCATGGTCAGGTTGAAAGTATCG
ACGTCATTCGCTCCATCTTTTTTGGCCTGTTAATTACGCCCTGGGCGGTCTATTTCTTATCCGTTGTTGTTGAACAACTG
GAAGAGTCAAGGCAGCGACTGTCGCGTCTGGTGCAAAAGCTGGAGGAGATGCGCGAGCGCGATCTCAAGCTTAACGTACA
GTTGAAGGACAATATTGCCCAGCTTAATCAGGAAATTGCCGATCGCGAAAAAGCGGAAGCGGAGCTGCATGAGACATTTG
AACAGCTAAAAGTAGAAATTAAAGAGCGTGAAGAAGCGCAAATCCAGCTAGAACAGCAATCCTCTTTTCTGCGCTCCTTT
CTGGACGCCTCGCCGGATTTGGTTTTTTATCGTAATGAGGATAAAGAATTTTCCGGCTGTAACCGCGCAATGGAATTGCT
AACCGGCAAGAGCGAAAAACAGCTGGTGCATTTGAAGCCGGAAGATGTGTACTCTCCCGAAGCGGCGGAGAAAGTCATTG
AAACCGATGAAAAAGTATTCCGCCATAACGTCTCCCTGACCTACGAACAGTGGCTGGATTACCCGGACGGACGAAAAGCC
TGCTTTGAAATTCGTAAAGTGCCTTATTACGACCGTGTCGGTAAACGTCATGGCCTGATGGGATTTGGTCGTGATATTAC
CGAACGTAAGCGTTATCAGGACGCGCTGGAACGCGCCAGCCGCGACAAGACCACGTTTATCTCTACCATCAGTCATGAGC
TGCGCACCCCGCTTAACGGCATCGTCGGTTTAAGCCGCATCCTGCTGGATACCGATCTCACCGCCGAACAGGAAAAATAC
CTTAAAACAATCCATGTCTCCGCCGTGACGTTAGGCAATATTTTCAATGACATCATTGATATGGATAAGATGGAGCGGCG
TAAGGTTCAGCTTGATAACCAACCGGTTGATTTCACCAGCTTTATGGCCGATCTGGAAAACCTTTCCGGTTTGCAGGCGC
AGCAAAAAGGGCTACGTTTTGTGCTTGAGCCGACGCTGCCGCTGCCGCACAAAGTCATTACCGACGGAACGCGTCTGCGC
CAGATTTTATGGAATTTGATCAGCAATGCGGTGAAGTTTACTCAGCAGGGCCAGGTGACGGTGCGGGCGCGCTATGATGA
AGGCGACATGCTGCACTTTGAAGTGGAAGATTCCGGGATCGGCATTCCGCAGGATGAGCAGGATAAAATTTTCGCCATGT
ATTATCAGGTGAAAGACAGTCATGGCGGTAAGCCGGCGACGGGTACCGGTATCGGGCTGGCGGTCTCCCGTCGGCTGGCG
AAAAATATGGGCGGCGATATTACCGTCTCCAGTCTGCCGGGCAAAGGATCGACCTTTACGCTAACGGTTCATGCGCCAGC
GGTGGCGGAAGAGGTGGAGGACGCCTTTGATGAAGACGACATGCCGCTGCCCGCGCTGCATGTTCTGCTGGTCGAAGATA
TTGAACTGAACGTGATCGTAGCGCGTTCGGTACTGGAAAAACTGGGGAACAGCGTGGATGTCGCGATGACCGGCAAGGCG
GCGCTGGAGATGTTCGCGCCGGGCGAATATGACCTGGTCTTACTGGATATTCAGCTACCGGATATGACGGGTCTGGATAT
CGCCAGAGAACTGACCCGTCGCCACACGCGGGAAGATTTACCGCCGCTGGTAGCGCTTACGGCTAACGTTCTGAAAGATA
AAAAAGAGTATCTGGACGCTGGTATGGACGATGTGCTGAGTAAGCCGCTGTCGGTGCCGGCCTTAACCGCGATGATTAAA
AAATTCTGGGATGCCACCGATAAAGAGGAGAGTACCGTGACGCCTGAAGAGAGCGATAAAGCGCAAGCGCTGCTGGATAT
CCCGATGCTGGAACAATACATCGAGTTGGTTGGGCCTAAATTGATCACCGACGGTCTCGCGGTGTTTGAAAAAATGATGC
CTGGCTATTTAAGCGTGCTGGAGTCCAATCTGACGGCGCGTGACAAAAAAGGCGTCGTTGAGGAAGGGCATAAGATTAAA
GGCGCCGCCGGTTCGGTAGGGCTGCGTCATCTGCAACAACTTGGCCAGCAAATCCAGTCGCCGGATCTTCCCGCCTGGGA
AGATAATGTCGCGGAATGGATTGAAGAGATGAAGCAGGAGTGGCAGCACGATGTCGCGGTGCTGAAAGCCTGGGTGGCAA
ACGCGGAAAAAAAATGA

Upstream 100 bases:

>100_bases
AGCGTAGCGTGATGAGGGGCGCTACGCATATTTCGCACAATATTCAACGCGGTTCCCATAATTGGGTATTATGTGCGAAG
TTGTGGTGAAGGAATCCTCT

Downstream 100 bases:

>100_bases
CCCCGGTTTGACCGGGGTGCGCGAATACTGCGCCAACACCAGGGAAATCGTGGCTGCGCCGTGCTTATTATGATGATGTC
AAAGGCGCAGTCCTGTTTTC

Product: aerobic respiration control sensor protein ArcB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 778; Mature: 778

Protein sequence:

>778_residues
MKQIRMLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTMVLHGQVESIDVIRSIFFGLLITPWAVYFLSVVVEQL
EESRQRLSRLVQKLEEMRERDLKLNVQLKDNIAQLNQEIADREKAEAELHETFEQLKVEIKEREEAQIQLEQQSSFLRSF
LDASPDLVFYRNEDKEFSGCNRAMELLTGKSEKQLVHLKPEDVYSPEAAEKVIETDEKVFRHNVSLTYEQWLDYPDGRKA
CFEIRKVPYYDRVGKRHGLMGFGRDITERKRYQDALERASRDKTTFISTISHELRTPLNGIVGLSRILLDTDLTAEQEKY
LKTIHVSAVTLGNIFNDIIDMDKMERRKVQLDNQPVDFTSFMADLENLSGLQAQQKGLRFVLEPTLPLPHKVITDGTRLR
QILWNLISNAVKFTQQGQVTVRARYDEGDMLHFEVEDSGIGIPQDEQDKIFAMYYQVKDSHGGKPATGTGIGLAVSRRLA
KNMGGDITVSSLPGKGSTFTLTVHAPAVAEEVEDAFDEDDMPLPALHVLLVEDIELNVIVARSVLEKLGNSVDVAMTGKA
ALEMFAPGEYDLVLLDIQLPDMTGLDIARELTRRHTREDLPPLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTAMIK
KFWDATDKEESTVTPEESDKAQALLDIPMLEQYIELVGPKLITDGLAVFEKMMPGYLSVLESNLTARDKKGVVEEGHKIK
GAAGSVGLRHLQQLGQQIQSPDLPAWEDNVAEWIEEMKQEWQHDVAVLKAWVANAEKK

Sequences:

>Translated_778_residues
MKQIRMLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTMVLHGQVESIDVIRSIFFGLLITPWAVYFLSVVVEQL
EESRQRLSRLVQKLEEMRERDLKLNVQLKDNIAQLNQEIADREKAEAELHETFEQLKVEIKEREEAQIQLEQQSSFLRSF
LDASPDLVFYRNEDKEFSGCNRAMELLTGKSEKQLVHLKPEDVYSPEAAEKVIETDEKVFRHNVSLTYEQWLDYPDGRKA
CFEIRKVPYYDRVGKRHGLMGFGRDITERKRYQDALERASRDKTTFISTISHELRTPLNGIVGLSRILLDTDLTAEQEKY
LKTIHVSAVTLGNIFNDIIDMDKMERRKVQLDNQPVDFTSFMADLENLSGLQAQQKGLRFVLEPTLPLPHKVITDGTRLR
QILWNLISNAVKFTQQGQVTVRARYDEGDMLHFEVEDSGIGIPQDEQDKIFAMYYQVKDSHGGKPATGTGIGLAVSRRLA
KNMGGDITVSSLPGKGSTFTLTVHAPAVAEEVEDAFDEDDMPLPALHVLLVEDIELNVIVARSVLEKLGNSVDVAMTGKA
ALEMFAPGEYDLVLLDIQLPDMTGLDIARELTRRHTREDLPPLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTAMIK
KFWDATDKEESTVTPEESDKAQALLDIPMLEQYIELVGPKLITDGLAVFEKMMPGYLSVLESNLTARDKKGVVEEGHKIK
GAAGSVGLRHLQQLGQQIQSPDLPAWEDNVAEWIEEMKQEWQHDVAVLKAWVANAEKK
>Mature_778_residues
MKQIRMLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTMVLHGQVESIDVIRSIFFGLLITPWAVYFLSVVVEQL
EESRQRLSRLVQKLEEMRERDLKLNVQLKDNIAQLNQEIADREKAEAELHETFEQLKVEIKEREEAQIQLEQQSSFLRSF
LDASPDLVFYRNEDKEFSGCNRAMELLTGKSEKQLVHLKPEDVYSPEAAEKVIETDEKVFRHNVSLTYEQWLDYPDGRKA
CFEIRKVPYYDRVGKRHGLMGFGRDITERKRYQDALERASRDKTTFISTISHELRTPLNGIVGLSRILLDTDLTAEQEKY
LKTIHVSAVTLGNIFNDIIDMDKMERRKVQLDNQPVDFTSFMADLENLSGLQAQQKGLRFVLEPTLPLPHKVITDGTRLR
QILWNLISNAVKFTQQGQVTVRARYDEGDMLHFEVEDSGIGIPQDEQDKIFAMYYQVKDSHGGKPATGTGIGLAVSRRLA
KNMGGDITVSSLPGKGSTFTLTVHAPAVAEEVEDAFDEDDMPLPALHVLLVEDIELNVIVARSVLEKLGNSVDVAMTGKA
ALEMFAPGEYDLVLLDIQLPDMTGLDIARELTRRHTREDLPPLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTAMIK
KFWDATDKEESTVTPEESDKAQALLDIPMLEQYIELVGPKLITDGLAVFEKMMPGYLSVLESNLTARDKKGVVEEGHKIK
GAAGSVGLRHLQQLGQQIQSPDLPAWEDNVAEWIEEMKQEWQHDVAVLKAWVANAEKK

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=778, Percent_Identity=93.8303341902314, Blast_Score=1472, Evalue=0.0,
Organism=Escherichia coli, GI1788713, Length=660, Percent_Identity=27.8787878787879, Blast_Score=202, Evalue=8e-53,
Organism=Escherichia coli, GI87081816, Length=513, Percent_Identity=27.0955165692008, Blast_Score=182, Evalue=6e-47,
Organism=Escherichia coli, GI1789149, Length=380, Percent_Identity=31.0526315789474, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI145693157, Length=248, Percent_Identity=34.2741935483871, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI1790436, Length=246, Percent_Identity=30.8943089430894, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1788549, Length=423, Percent_Identity=25.7683215130024, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1786912, Length=244, Percent_Identity=28.6885245901639, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI1786600, Length=359, Percent_Identity=26.7409470752089, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790861, Length=220, Percent_Identity=24.0909090909091, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI87082128, Length=224, Percent_Identity=26.7857142857143, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790346, Length=204, Percent_Identity=25.9803921568627, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788393, Length=226, Percent_Identity=23.8938053097345, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1786783, Length=239, Percent_Identity=24.2677824267782, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789402, Length=128, Percent_Identity=34.375, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=215, Percent_Identity=26.9767441860465, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 87959; Mature: 87959

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50894 HPT ; PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQIRMLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTMVLHGQVESIDVIRSIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FGLLITPWAVYFLSVVVEQLEESRQRLSRLVQKLEEMRERDLKLNVQLKDNIAQLNQEIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHH
DREKAEAELHETFEQLKVEIKEREEAQIQLEQQSSFLRSFLDASPDLVFYRNEDKEFSGC
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHH
NRAMELLTGKSEKQLVHLKPEDVYSPEAAEKVIETDEKVFRHNVSLTYEQWLDYPDGRKA
HHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEHHHHCCCCCCHHH
CFEIRKVPYYDRVGKRHGLMGFGRDITERKRYQDALERASRDKTTFISTISHELRTPLNG
HHHHHCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHH
IVGLSRILLDTDLTAEQEKYLKTIHVSAVTLGNIFNDIIDMDKMERRKVQLDNQPVDFTS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
FMADLENLSGLQAQQKGLRFVLEPTLPLPHKVITDGTRLRQILWNLISNAVKFTQQGQVT
HHHHHHHHCCCHHHHCCCEEEECCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEE
VRARYDEGDMLHFEVEDSGIGIPQDEQDKIFAMYYQVKDSHGGKPATGTGIGLAVSRRLA
EEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHH
KNMGGDITVSSLPGKGSTFTLTVHAPAVAEEVEDAFDEDDMPLPALHVLLVEDIELNVIV
HHCCCCEEEECCCCCCCEEEEEEECCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHH
ARSVLEKLGNSVDVAMTGKAALEMFAPGEYDLVLLDIQLPDMTGLDIARELTRRHTREDL
HHHHHHHCCCCEEEEEECHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCC
PPLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTAMIKKFWDATDKEESTVTPEESDK
CHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
AQALLDIPMLEQYIELVGPKLITDGLAVFEKMMPGYLSVLESNLTARDKKGVVEEGHKIK
HHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCC
GAAGSVGLRHLQQLGQQIQSPDLPAWEDNVAEWIEEMKQEWQHDVAVLKAWVANAEKK
CCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKQIRMLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTMVLHGQVESIDVIRSIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FGLLITPWAVYFLSVVVEQLEESRQRLSRLVQKLEEMRERDLKLNVQLKDNIAQLNQEIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHH
DREKAEAELHETFEQLKVEIKEREEAQIQLEQQSSFLRSFLDASPDLVFYRNEDKEFSGC
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHH
NRAMELLTGKSEKQLVHLKPEDVYSPEAAEKVIETDEKVFRHNVSLTYEQWLDYPDGRKA
HHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEHHHHCCCCCCHHH
CFEIRKVPYYDRVGKRHGLMGFGRDITERKRYQDALERASRDKTTFISTISHELRTPLNG
HHHHHCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHH
IVGLSRILLDTDLTAEQEKYLKTIHVSAVTLGNIFNDIIDMDKMERRKVQLDNQPVDFTS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
FMADLENLSGLQAQQKGLRFVLEPTLPLPHKVITDGTRLRQILWNLISNAVKFTQQGQVT
HHHHHHHHCCCHHHHCCCEEEECCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEE
VRARYDEGDMLHFEVEDSGIGIPQDEQDKIFAMYYQVKDSHGGKPATGTGIGLAVSRRLA
EEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHH
KNMGGDITVSSLPGKGSTFTLTVHAPAVAEEVEDAFDEDDMPLPALHVLLVEDIELNVIV
HHCCCCEEEECCCCCCCEEEEEEECCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHH
ARSVLEKLGNSVDVAMTGKAALEMFAPGEYDLVLLDIQLPDMTGLDIARELTRRHTREDL
HHHHHHHCCCCEEEEEECHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCC
PPLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTAMIKKFWDATDKEESTVTPEESDK
CHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
AQALLDIPMLEQYIELVGPKLITDGLAVFEKMMPGYLSVLESNLTARDKKGVVEEGHKIK
HHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCC
GAAGSVGLRHLQQLGQQIQSPDLPAWEDNVAEWIEEMKQEWQHDVAVLKAWVANAEKK
CCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]