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The map label for this gene is msrB [H]

Identifier: 194733920

GI number: 194733920

Start: 1336703

End: 1337116

Strand: Direct

Name: msrB [H]

Synonym: SeSA_A1385

Alternate gene names: 194733920

Gene position: 1336703-1337116 (Clockwise)

Preceding gene: 194734501

Following gene: 194738192

Centisome position: 28.39

GC content: 51.21

Gene sequence:

>414_bases
ATGGCTAACCAACCTTCAGCAGAAGAACTCAAGAAAAAATTGTCCGAAATGCAATTCTACGTGACGCAGGATCGTGGCAC
AGAACCGCCATTTACCGGACGCCTGCTACATAATAAACGCGATGGGGTTTATCACTGCCTGGTCTGTGATACGCCGCTTT
TTCACTCCCACACCAAATACGATTCAGGCTGCGGCTGGCCTAGCTTTTACCAGCCTGTCAGCGAAGAGGCGATTCGTTAC
ATAGACGATTTTTCTCATGGAATGCAGCGTGTCGAAATTCGTTGCGGTAACTGCGATGCGCATCTCGGACACGTTTTCCC
GGATGGTCCGCAGCCAACCGGTGAGCGCTATTGCGTTAACTCGGCCTCGCTGGCCTTTTCTGACGAGAAAAACGGCGATC
AACTGAAAGGCTGA

Upstream 100 bases:

>100_bases
CGCAATGATCAAGTTTAGAACAAAAGTTGGTACTGAGGTGTTAATGTTTTGTTAGAATCGGTCAGGCAATGTGAGCACGT
TTAAAGTGAGATGTGAGCAA

Downstream 100 bases:

>100_bases
AAAAACGATTCAGCAAATTATTCCACAGGAGCGGACACATCATGAATCTTGATGAGATCATTAACAGCATGACGCCGGAA
GTGTATCAACGTTTATCCAC

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MANQPSAEELKKKLSEMQFYVTQDRGTEPPFTGRLLHNKRDGVYHCLVCDTPLFHSHTKYDSGCGWPSFYQPVSEEAIRY
IDDFSHGMQRVEIRCGNCDAHLGHVFPDGPQPTGERYCVNSASLAFSDEKNGDQLKG

Sequences:

>Translated_137_residues
MANQPSAEELKKKLSEMQFYVTQDRGTEPPFTGRLLHNKRDGVYHCLVCDTPLFHSHTKYDSGCGWPSFYQPVSEEAIRY
IDDFSHGMQRVEIRCGNCDAHLGHVFPDGPQPTGERYCVNSASLAFSDEKNGDQLKG
>Mature_136_residues
ANQPSAEELKKKLSEMQFYVTQDRGTEPPFTGRLLHNKRDGVYHCLVCDTPLFHSHTKYDSGCGWPSFYQPVSEEAIRYI
DDFSHGMQRVEIRCGNCDAHLGHVFPDGPQPTGERYCVNSASLAFSDEKNGDQLKG

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=132, Percent_Identity=53.7878787878788, Blast_Score=165, Evalue=1e-41,
Organism=Homo sapiens, GI301336162, Length=132, Percent_Identity=53.7878787878788, Blast_Score=165, Evalue=1e-41,
Organism=Homo sapiens, GI73089054, Length=132, Percent_Identity=53.7878787878788, Blast_Score=165, Evalue=1e-41,
Organism=Homo sapiens, GI37620216, Length=132, Percent_Identity=53.7878787878788, Blast_Score=164, Evalue=2e-41,
Organism=Homo sapiens, GI117606353, Length=130, Percent_Identity=51.5384615384615, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI1788077, Length=137, Percent_Identity=85.4014598540146, Blast_Score=260, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17553450, Length=120, Percent_Identity=50, Blast_Score=119, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI115532676, Length=120, Percent_Identity=50, Blast_Score=119, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6319816, Length=135, Percent_Identity=43.7037037037037, Blast_Score=111, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24645799, Length=120, Percent_Identity=51.6666666666667, Blast_Score=131, Evalue=1e-31,
Organism=Drosophila melanogaster, GI45553335, Length=122, Percent_Identity=50.8196721311475, Blast_Score=131, Evalue=1e-31,
Organism=Drosophila melanogaster, GI21356369, Length=122, Percent_Identity=50.8196721311475, Blast_Score=131, Evalue=1e-31,
Organism=Drosophila melanogaster, GI221378664, Length=120, Percent_Identity=51.6666666666667, Blast_Score=129, Evalue=5e-31,
Organism=Drosophila melanogaster, GI221378662, Length=127, Percent_Identity=48.0314960629921, Blast_Score=127, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24645801, Length=133, Percent_Identity=46.6165413533835, Blast_Score=126, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24645804, Length=133, Percent_Identity=46.6165413533835, Blast_Score=126, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 15471; Mature: 15340

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANQPSAEELKKKLSEMQFYVTQDRGTEPPFTGRLLHNKRDGVYHCLVCDTPLFHSHTKY
CCCCCCHHHHHHHHHHHEEEEECCCCCCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCC
DSGCGWPSFYQPVSEEAIRYIDDFSHGMQRVEIRCGNCDAHLGHVFPDGPQPTGERYCVN
CCCCCCCHHHCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEECC
SASLAFSDEKNGDQLKG
CCCEEECCCCCCCCCCC
>Mature Secondary Structure 
ANQPSAEELKKKLSEMQFYVTQDRGTEPPFTGRLLHNKRDGVYHCLVCDTPLFHSHTKY
CCCCCHHHHHHHHHHHEEEEECCCCCCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCC
DSGCGWPSFYQPVSEEAIRYIDDFSHGMQRVEIRCGNCDAHLGHVFPDGPQPTGERYCVN
CCCCCCCHHHCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEECC
SASLAFSDEKNGDQLKG
CCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA