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The map label for this gene is yfkJ [H]

Identifier: 194334652

GI number: 194334652

Start: 2025208

End: 2025711

Strand: Reverse

Name: yfkJ [H]

Synonym: Paes_1853

Alternate gene names: 194334652

Gene position: 2025711-2025208 (Counterclockwise)

Preceding gene: 194334657

Following gene: 194334651

Centisome position: 80.61

GC content: 48.21

Gene sequence:

>504_bases
ATGCTTCTCCGTGTATTATTTGTCTGTTATGAAAATATCTGCCGTTCTCCTATGGCGGAAGGTATTTTTTCGGCTCTCGT
CAGGCGCGATGCACGCGCAGAGGGTATTATTGTCGAATCGGCAGGGACGGTATGCTATCAGAAAGGATCTCTTCCGGATA
GCCGTGCTGTAATGGTTGCAGGCAGATATGGCATTGATATCTCCCCTTTGCGGGCCAGATGTATCGATGAGCTGGATCTT
GGTTTGTTTGACTGGATCTTTACCATGGATGCAGAGAATTATCAGGATGTTTCGAGCTGTTTCGCAGGTGCCGGACCGGT
GTATATGATGACGCATTTTGATCCTTATGCAGCCTGTCAGGATATCGCTGATCCCTACTACGGCAGTGAAGATGATTTTC
TGCGGGTCTATAAGCAGCTTGATCGGGCCATAGGGTATGCGTACAGGCAGATTCTCGGGGGTTTGCATAGCTCGGAATCG
TCTGACATCAATGGATTTTCATGA

Upstream 100 bases:

>100_bases
CCGGTTTATTCACTTCTTCAGAGCATTTGACATAATCCCTGCGGATTGTTTTCTTTGCTTACCTTATACGTATTCTGATC
AAACAGGTCACACGCACAGT

Downstream 100 bases:

>100_bases
TGATGATGGAGTAATTGTATGAAGTATACCTTTATTGTTAATCCCGTTGCAGGAAGCAGGCGCCTTTTCGCTCCTGCCAC
CGACATGCTGAAGACTCTTT

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MLLRVLFVCYENICRSPMAEGIFSALVRRDARAEGIIVESAGTVCYQKGSLPDSRAVMVAGRYGIDISPLRARCIDELDL
GLFDWIFTMDAENYQDVSSCFAGAGPVYMMTHFDPYAACQDIADPYYGSEDDFLRVYKQLDRAIGYAYRQILGGLHSSES
SDINGFS

Sequences:

>Translated_167_residues
MLLRVLFVCYENICRSPMAEGIFSALVRRDARAEGIIVESAGTVCYQKGSLPDSRAVMVAGRYGIDISPLRARCIDELDL
GLFDWIFTMDAENYQDVSSCFAGAGPVYMMTHFDPYAACQDIADPYYGSEDDFLRVYKQLDRAIGYAYRQILGGLHSSES
SDINGFS
>Mature_167_residues
MLLRVLFVCYENICRSPMAEGIFSALVRRDARAEGIIVESAGTVCYQKGSLPDSRAVMVAGRYGIDISPLRARCIDELDL
GLFDWIFTMDAENYQDVSSCFAGAGPVYMMTHFDPYAACQDIADPYYGSEDDFLRVYKQLDRAIGYAYRQILGGLHSSES
SDINGFS

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=145, Percent_Identity=40, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI6005988, Length=145, Percent_Identity=37.2413793103448, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI78706770, Length=138, Percent_Identity=34.0579710144928, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI78706772, Length=138, Percent_Identity=34.0579710144928, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 18591; Mature: 18591

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLRVLFVCYENICRSPMAEGIFSALVRRDARAEGIIVESAGTVCYQKGSLPDSRAVMVA
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEECCCCEEEECCCCCCCCEEEEE
GRYGIDISPLRARCIDELDLGLFDWIFTMDAENYQDVSSCFAGAGPVYMMTHFDPYAACQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEECCCHHHHHH
DIADPYYGSEDDFLRVYKQLDRAIGYAYRQILGGLHSSESSDINGFS
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLLRVLFVCYENICRSPMAEGIFSALVRRDARAEGIIVESAGTVCYQKGSLPDSRAVMVA
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEECCCCEEEECCCCCCCCEEEEE
GRYGIDISPLRARCIDELDLGLFDWIFTMDAENYQDVSSCFAGAGPVYMMTHFDPYAACQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEECCCHHHHHH
DIADPYYGSEDDFLRVYKQLDRAIGYAYRQILGGLHSSESSDINGFS
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]