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The map label for this gene is trpG [H]

Identifier: 194334649

GI number: 194334649

Start: 2022355

End: 2022936

Strand: Reverse

Name: trpG [H]

Synonym: Paes_1850

Alternate gene names: 194334649

Gene position: 2022936-2022355 (Counterclockwise)

Preceding gene: 194334650

Following gene: 194334648

Centisome position: 80.5

GC content: 48.97

Gene sequence:

>582_bases
ATGGTCATTGTTATCGATAATTACGACTCTTTTACCTATAACCTTGTTCAATACCTGGGCGAACTTGGTGCGGATGTGCA
TGTCTACCGTAACGATGAGATAAGCGTCGATGAGGTTCTTCAGCTTGAACCAGAGAGAATTGTCATTTCTCCAGGGCCCG
GCGTTCCAGAGGACGCAGGAATTTCCATTGCGCTGATTAACGCGGTCAAAGGTAAAATTCCTCTTCTTGGAGTCTGTCTC
GGCCATCAGGCTATCGGCCAGGCCCTTGGAGGAAAAGTGGTCAGGGCGGCGGCGGTTATGCATGGAAAAACATCACAGAT
ATATCATAACGATACCGGGATTTTTCATGGGCTTCCTAATCCTTTTATCGCTACCCGCTATCATTCGCTGATCGTTGAGC
GCCAGACGCTGCCATCCATCCTGAAGGTCAGTGCGTGGACCGCTGATGAGGTTATTATGGGGATGGATTGCCGGGAGCTG
ATGCTCTATGGTGTGCAGTTCCATCCCGAATCAATCATGACCCATGAAGGAAAGAGTATCATCCGGAATTTTCTGGACCT
TTCCGGTCATACAAACGAGTAG

Upstream 100 bases:

>100_bases
GGACGATCTGTATGAAACCATGTTTCGATTTGTCGCTTCGCGATCCCTTGGTGAGAGGGTATCTCTTTAAGTATTATTTA
TCTCAATTAATAGATCGAGT

Downstream 100 bases:

>100_bases
AGCCATGCCTTCGTCGGATAAAAGCACTAAACGTCAGGACGTTCAGCCTGTGCCGGTTCATCCGCCGGACCAGCGTTTTG
CCAGGCAGACAGATTTTTCG

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MVIVIDNYDSFTYNLVQYLGELGADVHVYRNDEISVDEVLQLEPERIVISPGPGVPEDAGISIALINAVKGKIPLLGVCL
GHQAIGQALGGKVVRAAAVMHGKTSQIYHNDTGIFHGLPNPFIATRYHSLIVERQTLPSILKVSAWTADEVIMGMDCREL
MLYGVQFHPESIMTHEGKSIIRNFLDLSGHTNE

Sequences:

>Translated_193_residues
MVIVIDNYDSFTYNLVQYLGELGADVHVYRNDEISVDEVLQLEPERIVISPGPGVPEDAGISIALINAVKGKIPLLGVCL
GHQAIGQALGGKVVRAAAVMHGKTSQIYHNDTGIFHGLPNPFIATRYHSLIVERQTLPSILKVSAWTADEVIMGMDCREL
MLYGVQFHPESIMTHEGKSIIRNFLDLSGHTNE
>Mature_193_residues
MVIVIDNYDSFTYNLVQYLGELGADVHVYRNDEISVDEVLQLEPERIVISPGPGVPEDAGISIALINAVKGKIPLLGVCL
GHQAIGQALGGKVVRAAAVMHGKTSQIYHNDTGIFHGLPNPFIATRYHSLIVERQTLPSILKVSAWTADEVIMGMDCREL
MLYGVQFHPESIMTHEGKSIIRNFLDLSGHTNE

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=57.2972972972973, Blast_Score=229, Evalue=7e-62,
Organism=Escherichia coli, GI1787517, Length=187, Percent_Identity=38.5026737967914, Blast_Score=138, Evalue=2e-34,
Organism=Escherichia coli, GI1786215, Length=158, Percent_Identity=27.8481012658228, Blast_Score=67, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6322638, Length=193, Percent_Identity=50.259067357513, Blast_Score=197, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6324361, Length=213, Percent_Identity=36.150234741784, Blast_Score=102, Evalue=4e-23,
Organism=Drosophila melanogaster, GI281365319, Length=141, Percent_Identity=32.6241134751773, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 21175; Mature: 21175

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIVIDNYDSFTYNLVQYLGELGADVHVYRNDEISVDEVLQLEPERIVISPGPGVPEDAG
CEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCHHHHHCCCCCEEEECCCCCCCCCCC
ISIALINAVKGKIPLLGVCLGHQAIGQALGGKVVRAAAVMHGKTSQIYHNDTGIFHGLPN
EEEEEEECCCCCCCEEEEECCHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCEECCCCC
PFIATRYHSLIVERQTLPSILKVSAWTADEVIMGMDCRELMLYGVQFHPESIMTHEGKSI
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHCCCEECCHHHHCCCCHHH
IRNFLDLSGHTNE
HHHHHHCCCCCCC
>Mature Secondary Structure
MVIVIDNYDSFTYNLVQYLGELGADVHVYRNDEISVDEVLQLEPERIVISPGPGVPEDAG
CEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCHHHHHCCCCCEEEECCCCCCCCCCC
ISIALINAVKGKIPLLGVCLGHQAIGQALGGKVVRAAAVMHGKTSQIYHNDTGIFHGLPN
EEEEEEECCCCCCCEEEEECCHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCEECCCCC
PFIATRYHSLIVERQTLPSILKVSAWTADEVIMGMDCRELMLYGVQFHPESIMTHEGKSI
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHCCCEECCHHHHCCCCHHH
IRNFLDLSGHTNE
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2105306; 10984043 [H]