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The map label for this gene is dnaX [H]

Identifier: 194333391

GI number: 194333391

Start: 590605

End: 591774

Strand: Reverse

Name: dnaX [H]

Synonym: Paes_0548

Alternate gene names: 194333391

Gene position: 591774-590605 (Counterclockwise)

Preceding gene: 194333392

Following gene: 194333389

Centisome position: 23.55

GC content: 52.14

Gene sequence:

>1170_bases
ATGAGCTGGGACAACATCATCGGTCAATCGCTGCAGGTCAATATTCTCAAAAAATCTCTTGCTGCCGACCGACTGGCTCA
TGCCTATCTCTTTTCCGGTCCTGAAGGCATCGGAAAAGAAGCCGTAGCTTTCGAACTGGCCAAGCAGCTCAACTGTTCAC
AGCGCTCTCCTGATCCCCAAAAAGGGTCGTGCGATATCTGTGAAAGCTGTCTTCAGGCTACCGCCTTTCTCCACCCGAAC
ATCGAATACGTCTTCCCGGTAGAGTCCGTGCTGCTCGACCAGATCGACCCGTCGAAAAGTGAAAACAAAAAATTCAGCGA
AGCAAAAGCCCGCTACGAAGCGCTTATAGAACAAAAAAAGCGGAACCCCTATTTCACGCCCGTCATGGAACGATCCATGG
CAATTCTTACCGAGCAGGTCAGCGATCTTCAGCAGAAAGCAGCCTTCATGCCCTCTGGAGGAGGAAGAAAAGTCTTTATC
ATCTCCCAGGCCGAAAAACTCAATCAGTCTGCAGCAAACAAGCTGCTCAAGCTGCTCGAAGAACCTCCAAAACACGTCCT
GTTCATTCTCGTCTCATCCAGACCGGAATCCATTCTTCCGACCATACGCTCACGCTGTCAGATACTCAAATTCTCGAGGA
TAAAACCAGCCGAGATGGAAGCATGGCTTTCAGCAGCCTGTCCCGCTGCAGATGAGGATATCCTGCGCTTCATTGTCAGC
GCTTCACGAGGCAACCTGGAAAAAGCGCTCGACCTGTCACGCAGCATAACAGATCAAGCGGCAATGACACTTCCGGGACT
CGAACTGCGCAATCGAGCTATCGACTGGCTGCGCAACCTGCTGACACCCAGGCGCCTCCAGGAAGCGATCCGCGAAACCG
AAGAGATGGCAAAAAATCTTTCCCGTCAGGAGATCGCATCCATGCTCGCAAGCCTCCTCCTCTTCTTTCAGGATATCAAC
CACCGAAGGATAGACCCCCGCTGGGAAGGGCTCAACAATCCTGATCTCGAATCATCGGTTATCCGTTTCGTCCAGAACTT
CAGAAAGCCGGACTTTTACGAAGTGTCGGTCGCGACCGAAACGACCATCCGCTCCATCATGCGCAACGCCAACCCGTTTC
TCACCCTCTCGGCATACGCCATTCGGATAAAACAGCTGATTGCAGGATAG

Upstream 100 bases:

>100_bases
GGCGCACCGTTTTCTGTGCGCCCTGCTGTTGTATATCGACAAATCACCATCTCAAAGAAACGGTGCTGAAGAGGCCAATA
ACTCAGACTGAAAACACACT

Downstream 100 bases:

>100_bases
AGACGGTACTGAGTTCTGAGTTCTGAGTGCTGGGTGCTGGGTGCTGGGTGCTGGGTGCTGGGTGCTGGGTGCTGGGTGCT
GGGTGCTGAACAGAAAAAGT

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MSWDNIIGQSLQVNILKKSLAADRLAHAYLFSGPEGIGKEAVAFELAKQLNCSQRSPDPQKGSCDICESCLQATAFLHPN
IEYVFPVESVLLDQIDPSKSENKKFSEAKARYEALIEQKKRNPYFTPVMERSMAILTEQVSDLQQKAAFMPSGGGRKVFI
ISQAEKLNQSAANKLLKLLEEPPKHVLFILVSSRPESILPTIRSRCQILKFSRIKPAEMEAWLSAACPAADEDILRFIVS
ASRGNLEKALDLSRSITDQAAMTLPGLELRNRAIDWLRNLLTPRRLQEAIRETEEMAKNLSRQEIASMLASLLLFFQDIN
HRRIDPRWEGLNNPDLESSVIRFVQNFRKPDFYEVSVATETTIRSIMRNANPFLTLSAYAIRIKQLIAG

Sequences:

>Translated_389_residues
MSWDNIIGQSLQVNILKKSLAADRLAHAYLFSGPEGIGKEAVAFELAKQLNCSQRSPDPQKGSCDICESCLQATAFLHPN
IEYVFPVESVLLDQIDPSKSENKKFSEAKARYEALIEQKKRNPYFTPVMERSMAILTEQVSDLQQKAAFMPSGGGRKVFI
ISQAEKLNQSAANKLLKLLEEPPKHVLFILVSSRPESILPTIRSRCQILKFSRIKPAEMEAWLSAACPAADEDILRFIVS
ASRGNLEKALDLSRSITDQAAMTLPGLELRNRAIDWLRNLLTPRRLQEAIRETEEMAKNLSRQEIASMLASLLLFFQDIN
HRRIDPRWEGLNNPDLESSVIRFVQNFRKPDFYEVSVATETTIRSIMRNANPFLTLSAYAIRIKQLIAG
>Mature_388_residues
SWDNIIGQSLQVNILKKSLAADRLAHAYLFSGPEGIGKEAVAFELAKQLNCSQRSPDPQKGSCDICESCLQATAFLHPNI
EYVFPVESVLLDQIDPSKSENKKFSEAKARYEALIEQKKRNPYFTPVMERSMAILTEQVSDLQQKAAFMPSGGGRKVFII
SQAEKLNQSAANKLLKLLEEPPKHVLFILVSSRPESILPTIRSRCQILKFSRIKPAEMEAWLSAACPAADEDILRFIVSA
SRGNLEKALDLSRSITDQAAMTLPGLELRNRAIDWLRNLLTPRRLQEAIRETEEMAKNLSRQEIASMLASLLLFFQDINH
RRIDPRWEGLNNPDLESSVIRFVQNFRKPDFYEVSVATETTIRSIMRNANPFLTLSAYAIRIKQLIAG

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=264, Percent_Identity=28.030303030303, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 43905; Mature: 43774

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWDNIIGQSLQVNILKKSLAADRLAHAYLFSGPEGIGKEAVAFELAKQLNCSQRSPDPQ
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
KGSCDICESCLQATAFLHPNIEYVFPVESVLLDQIDPSKSENKKFSEAKARYEALIEQKK
CCCHHHHHHHHHHHHHHCCCCEEECCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
RNPYFTPVMERSMAILTEQVSDLQQKAAFMPSGGGRKVFIISQAEKLNQSAANKLLKLLE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHH
EPPKHVLFILVSSRPESILPTIRSRCQILKFSRIKPAEMEAWLSAACPAADEDILRFIVS
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
ASRGNLEKALDLSRSITDQAAMTLPGLELRNRAIDWLRNLLTPRRLQEAIRETEEMAKNL
HCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
SRQEIASMLASLLLFFQDINHRRIDPRWEGLNNPDLESSVIRFVQNFRKPDFYEVSVATE
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEHHH
TTIRSIMRNANPFLTLSAYAIRIKQLIAG
HHHHHHHHCCCCCEEHHHHHHHHHHHHCC
>Mature Secondary Structure 
SWDNIIGQSLQVNILKKSLAADRLAHAYLFSGPEGIGKEAVAFELAKQLNCSQRSPDPQ
CCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
KGSCDICESCLQATAFLHPNIEYVFPVESVLLDQIDPSKSENKKFSEAKARYEALIEQKK
CCCHHHHHHHHHHHHHHCCCCEEECCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
RNPYFTPVMERSMAILTEQVSDLQQKAAFMPSGGGRKVFIISQAEKLNQSAANKLLKLLE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHH
EPPKHVLFILVSSRPESILPTIRSRCQILKFSRIKPAEMEAWLSAACPAADEDILRFIVS
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
ASRGNLEKALDLSRSITDQAAMTLPGLELRNRAIDWLRNLLTPRRLQEAIRETEEMAKNL
HCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
SRQEIASMLASLLLFFQDINHRRIDPRWEGLNNPDLESSVIRFVQNFRKPDFYEVSVATE
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEHHH
TTIRSIMRNANPFLTLSAYAIRIKQLIAG
HHHHHHHHCCCCCEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]