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The map label for this gene is trpD

Identifier: 194333389

GI number: 194333389

Start: 588074

End: 589129

Strand: Reverse

Name: trpD

Synonym: Paes_0546

Alternate gene names: 194333389

Gene position: 589129-588074 (Counterclockwise)

Preceding gene: 194333391

Following gene: 194333388

Centisome position: 23.44

GC content: 53.22

Gene sequence:

>1056_bases
ATGCAACAGAACGCATTACTTCAACAGCTTCTTGCAGATAACGATCTCAGCTCCGCTGAGATGGAAGCCTGCATAACCGC
CATCATGACCGGCGGTTTTTCAGATATCGCTATTGCCGCCATTCTTGCACTCCTCCAGAAAAAAGGGGTTAAAGCAACGG
AACTCAGCGGAGCATATCGCGCCATGATGACACACGCCATCCCGATCGAGCTTGACGAACATGCTGTCGATACCTGCGGA
ACAGGCGGAGACCACGCAGGCACCTTCAACGTCTCTACTGTTGCCGCAATCATTGCCAACGGAGCGGGCGTCAGCATAGC
AAAACATGGCAACCGCTCGGTTACAAGCCGCTGCGGCAGTGCCGATGTCCTTGAAGCTCTGGGCTACACCATCGACCTGA
GCCCGGAGGCAACCATGGAACTGTTCAGCAAAACCCGGTTCGCATTTCTCTTTGCTCCACTCTATCACCCATCGATGAAA
GCCGTTGCCCATATCCGCAGGGAACTCGGCATCCGAACGATTTTCAACACGCTCGGCCCTCTTGCCAATCCGGCCTGCGT
CAAACGTCAGGTGATAGGGGTCTATGATCCGTCGATCATGGAGCTCTATATCGAAACCCTTATGAAAACGGGCTGCCGCC
ACGCAATGGTCGTCCATGGAAAAACAGAAAGCGGTGCCCCACTCGACGAATCGAGCGTCTGCGGAATCACTCATATCAGC
GAGCTTCACGAAGGAGTGGTCTCCTATCACAGCGTCATTCCCGAGGAGTTCGGACTCTCCCGATGGAAAACAGCCGATCT
GAAAGGCGGCGACCGGGAAGATAACGCAATGATCATCCGCAGAATCCTCGACGGTTCGGCATCTCAGGCTCAAATTGATG
CGTCAATCTACGCCGCTGCCATGGCCTGTTACGTCTCCGGCAAAGCGACCTGCATTGACGAAGGATTGTGTCTTTGCAAA
GAAAGTCTTGAAAACGGCGACGCAGCAAAGAATTTCTCACGTATTCTTGATTTGAATCGTGAAATTGCAGACAAACACCG
CACTGCGGTCAACTAA

Upstream 100 bases:

>100_bases
TACCGGACAGCGCCTCGTGAACGTCTGTATGAGCAATCATCGGCCTGTTTTTAATGTACGATCTTAAAATTTTTTACCAT
TCGTCATTGCACTGTTTTCC

Downstream 100 bases:

>100_bases
ATGCTTACATTTCTGCAGAAAAACTCGTATAATTGTTGCTTTGTTTTCAGACGAAGAGTCAAAGAGTAGACAATGAACGG
TCGCAACGCAGTCAACAGTA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MQQNALLQQLLADNDLSSAEMEACITAIMTGGFSDIAIAAILALLQKKGVKATELSGAYRAMMTHAIPIELDEHAVDTCG
TGGDHAGTFNVSTVAAIIANGAGVSIAKHGNRSVTSRCGSADVLEALGYTIDLSPEATMELFSKTRFAFLFAPLYHPSMK
AVAHIRRELGIRTIFNTLGPLANPACVKRQVIGVYDPSIMELYIETLMKTGCRHAMVVHGKTESGAPLDESSVCGITHIS
ELHEGVVSYHSVIPEEFGLSRWKTADLKGGDREDNAMIIRRILDGSASQAQIDASIYAAAMACYVSGKATCIDEGLCLCK
ESLENGDAAKNFSRILDLNREIADKHRTAVN

Sequences:

>Translated_351_residues
MQQNALLQQLLADNDLSSAEMEACITAIMTGGFSDIAIAAILALLQKKGVKATELSGAYRAMMTHAIPIELDEHAVDTCG
TGGDHAGTFNVSTVAAIIANGAGVSIAKHGNRSVTSRCGSADVLEALGYTIDLSPEATMELFSKTRFAFLFAPLYHPSMK
AVAHIRRELGIRTIFNTLGPLANPACVKRQVIGVYDPSIMELYIETLMKTGCRHAMVVHGKTESGAPLDESSVCGITHIS
ELHEGVVSYHSVIPEEFGLSRWKTADLKGGDREDNAMIIRRILDGSASQAQIDASIYAAAMACYVSGKATCIDEGLCLCK
ESLENGDAAKNFSRILDLNREIADKHRTAVN
>Mature_351_residues
MQQNALLQQLLADNDLSSAEMEACITAIMTGGFSDIAIAAILALLQKKGVKATELSGAYRAMMTHAIPIELDEHAVDTCG
TGGDHAGTFNVSTVAAIIANGAGVSIAKHGNRSVTSRCGSADVLEALGYTIDLSPEATMELFSKTRFAFLFAPLYHPSMK
AVAHIRRELGIRTIFNTLGPLANPACVKRQVIGVYDPSIMELYIETLMKTGCRHAMVVHGKTESGAPLDESSVCGITHIS
ELHEGVVSYHSVIPEEFGLSRWKTADLKGGDREDNAMIIRRILDGSASQAQIDASIYAAAMACYVSGKATCIDEGLCLCK
ESLENGDAAKNFSRILDLNREIADKHRTAVN

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=281, Percent_Identity=35.9430604982206, Blast_Score=170, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6320561, Length=274, Percent_Identity=30.2919708029197, Blast_Score=115, Evalue=8e-27,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_PROA2 (B4S5K5)

Other databases:

- EMBL:   CP001108
- RefSeq:   YP_002015249.1
- ProteinModelPortal:   B4S5K5
- SMR:   B4S5K5
- GeneID:   6459422
- GenomeReviews:   CP001108_GR
- KEGG:   paa:Paes_0546
- HOGENOM:   HBG559996
- OMA:   GSADIME
- ProtClustDB:   PRK00188
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 37546; Mature: 37546

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQNALLQQLLADNDLSSAEMEACITAIMTGGFSDIAIAAILALLQKKGVKATELSGAYR
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
AMMTHAIPIELDEHAVDTCGTGGDHAGTFNVSTVAAIIANGAGVSIAKHGNRSVTSRCGS
HHHHHCCCCEECCHHHHHCCCCCCCCCEEHHHHHHHHHHCCCCEEEEECCCCHHHHHCCC
ADVLEALGYTIDLSPEATMELFSKTRFAFLFAPLYHPSMKAVAHIRRELGIRTIFNTLGP
HHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
LANPACVKRQVIGVYDPSIMELYIETLMKTGCRHAMVVHGKTESGAPLDESSVCGITHIS
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHH
ELHEGVVSYHSVIPEEFGLSRWKTADLKGGDREDNAMIIRRILDGSASQAQIDASIYAAA
HHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
MACYVSGKATCIDEGLCLCKESLENGDAAKNFSRILDLNREIADKHRTAVN
HHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQQNALLQQLLADNDLSSAEMEACITAIMTGGFSDIAIAAILALLQKKGVKATELSGAYR
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
AMMTHAIPIELDEHAVDTCGTGGDHAGTFNVSTVAAIIANGAGVSIAKHGNRSVTSRCGS
HHHHHCCCCEECCHHHHHCCCCCCCCCEEHHHHHHHHHHCCCCEEEEECCCCHHHHHCCC
ADVLEALGYTIDLSPEATMELFSKTRFAFLFAPLYHPSMKAVAHIRRELGIRTIFNTLGP
HHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
LANPACVKRQVIGVYDPSIMELYIETLMKTGCRHAMVVHGKTESGAPLDESSVCGITHIS
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHH
ELHEGVVSYHSVIPEEFGLSRWKTADLKGGDREDNAMIIRRILDGSASQAQIDASIYAAA
HHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
MACYVSGKATCIDEGLCLCKESLENGDAAKNFSRILDLNREIADKHRTAVN
HHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA