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The map label for this gene is glmM [H]

Identifier: 194333255

GI number: 194333255

Start: 446685

End: 448067

Strand: Reverse

Name: glmM [H]

Synonym: Paes_0411

Alternate gene names: 194333255

Gene position: 448067-446685 (Counterclockwise)

Preceding gene: 194333262

Following gene: 194333254

Centisome position: 17.83

GC content: 48.37

Gene sequence:

>1383_bases
ATGCAAGTCAAATTCGGCACCGACGGCTGGAGAGCCATTATTGCGGAAGAATTCACATTTGCTAACCTCAAACGAGTCAC
CCTTGCTGCAGCAGAATATTTCCTGAACCAGCCCGACAGCTTGAGGGGTATCTGCCTCGGATACGATACTCGCTTCATGT
CGGCTGACTTTGCACGCTACAGTGCAGAAATTTTTTCATCAAAAGGGCTACGCGTTTTTCTTTCAGACTCTTTTGTTCCG
ACACCTGCTGTATCGCTGTACACCAAAGAAAAAAAGCTGGCTGGCGGAGTTGTGATTACCGCATCACACAATCCCCCTGT
CTACAACGGTTTTAAAATCAAAGACAGCTATGGTGGATCTGCACATCCGCAATCAATCGCCATTATAGAAGAGAATCTCG
AACACGTCGATGCTGAAGAACCGATAGTTCCGAATGAACACCTTATTGAACTGACCGACATTAAAGAGTTTTACCTGCAG
AATCTCAGCAGAAACATCGACCTCAAGAGCATCCATGACACTCAGATGACCATAGCCCATAATGCCATGTTCGGTGCCGG
GCAACAAATCATATCAGGTCTCTTCGACGAATCGACGGTCAGCAACTATCACTGCTCTCTGAATCCGGGATTCATGGGCA
TAAACCCTGAACCTGTAGCACAAAACGTTATGGATTTCGTTGACTTTGTCAAGGAAGTCAAAACAGACGTCGCCATCATC
AACGACGGCGATGCCGACAGAGTGGGCATGCTGGATGAGAACGGTTCGTTCATTGATTCGCATAAAATCTTTGCAATCGT
GCTCAAGTACCTTGTCGAAGACAGGGGAGAAAAAGGAGAAATCGCCAAAACATTTGCCCTTACTGACGTCATCGACAGTA
TCTGCCGGAAACACGATCTCCCGCTGCACATTCTGCCGGTCGGCTTCAAACATGTCAGCAAACTGATGACGACCAGCAAC
ATCCTGATGGGAGGTGAAGAGTCGGGAGGTATAGGCATAACATCCTACCTCCCCGAGCGCGATGGCATCTATATTGGTCT
TCTTGTGCTGGAAATCATGGCAAAGAAGAAAATGACGCTTGGTGAACTTGTCAAAGAGCTCTTCGACGAGTATGGATATT
TCTACTATGAACGTCATGACCTGCATGTCAGCCAGGAAAAAAAACAGGCCATCATGCGACGAGCCGCCGGAGGCGATATC
ACTGCGATTGGTCCATACCCGGTCACCCGATTCAACGACCTTGACGGTTACAAGTATCATTTCAAGGGAGGATGGCTGCT
GATCAGGCCTTCGGGGACCGAACCGGTCCTGCGGATATACTGTGAGGCCGATTCAAGAGAGAAAGCCCAAAAAGCCCTCG
CATTTGCCGAAAAGATAGCCTGA

Upstream 100 bases:

>100_bases
TGGAACATCAGTGAGGAAAAGCTATCTTTTTCTTACAGTAAACTATAAGAGCAAGCAATAGCGTAGGTTCCAACTCCCAT
TATATCAAATTCAACAGAGA

Downstream 100 bases:

>100_bases
ACCCGACCATTGCGCCATGATCAAGGACAATCACGCGTATAAAGACAGGTTTTCCGTTCAAGCCGCCGAATATCGAAGGT
TCAGGCCAACCTACCCACTG

Product: phosphomannomutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MQVKFGTDGWRAIIAEEFTFANLKRVTLAAAEYFLNQPDSLRGICLGYDTRFMSADFARYSAEIFSSKGLRVFLSDSFVP
TPAVSLYTKEKKLAGGVVITASHNPPVYNGFKIKDSYGGSAHPQSIAIIEENLEHVDAEEPIVPNEHLIELTDIKEFYLQ
NLSRNIDLKSIHDTQMTIAHNAMFGAGQQIISGLFDESTVSNYHCSLNPGFMGINPEPVAQNVMDFVDFVKEVKTDVAII
NDGDADRVGMLDENGSFIDSHKIFAIVLKYLVEDRGEKGEIAKTFALTDVIDSICRKHDLPLHILPVGFKHVSKLMTTSN
ILMGGEESGGIGITSYLPERDGIYIGLLVLEIMAKKKMTLGELVKELFDEYGYFYYERHDLHVSQEKKQAIMRRAAGGDI
TAIGPYPVTRFNDLDGYKYHFKGGWLLIRPSGTEPVLRIYCEADSREKAQKALAFAEKIA

Sequences:

>Translated_460_residues
MQVKFGTDGWRAIIAEEFTFANLKRVTLAAAEYFLNQPDSLRGICLGYDTRFMSADFARYSAEIFSSKGLRVFLSDSFVP
TPAVSLYTKEKKLAGGVVITASHNPPVYNGFKIKDSYGGSAHPQSIAIIEENLEHVDAEEPIVPNEHLIELTDIKEFYLQ
NLSRNIDLKSIHDTQMTIAHNAMFGAGQQIISGLFDESTVSNYHCSLNPGFMGINPEPVAQNVMDFVDFVKEVKTDVAII
NDGDADRVGMLDENGSFIDSHKIFAIVLKYLVEDRGEKGEIAKTFALTDVIDSICRKHDLPLHILPVGFKHVSKLMTTSN
ILMGGEESGGIGITSYLPERDGIYIGLLVLEIMAKKKMTLGELVKELFDEYGYFYYERHDLHVSQEKKQAIMRRAAGGDI
TAIGPYPVTRFNDLDGYKYHFKGGWLLIRPSGTEPVLRIYCEADSREKAQKALAFAEKIA
>Mature_460_residues
MQVKFGTDGWRAIIAEEFTFANLKRVTLAAAEYFLNQPDSLRGICLGYDTRFMSADFARYSAEIFSSKGLRVFLSDSFVP
TPAVSLYTKEKKLAGGVVITASHNPPVYNGFKIKDSYGGSAHPQSIAIIEENLEHVDAEEPIVPNEHLIELTDIKEFYLQ
NLSRNIDLKSIHDTQMTIAHNAMFGAGQQIISGLFDESTVSNYHCSLNPGFMGINPEPVAQNVMDFVDFVKEVKTDVAII
NDGDADRVGMLDENGSFIDSHKIFAIVLKYLVEDRGEKGEIAKTFALTDVIDSICRKHDLPLHILPVGFKHVSKLMTTSN
ILMGGEESGGIGITSYLPERDGIYIGLLVLEIMAKKKMTLGELVKELFDEYGYFYYERHDLHVSQEKKQAIMRRAAGGDI
TAIGPYPVTRFNDLDGYKYHFKGGWLLIRPSGTEPVLRIYCEADSREKAQKALAFAEKIA

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI21361621, Length=392, Percent_Identity=25.5102040816327, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI290463102, Length=392, Percent_Identity=24.7448979591837, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI63055049, Length=526, Percent_Identity=24.1444866920152, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI133922562, Length=375, Percent_Identity=24.5333333333333, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI31377548, Length=429, Percent_Identity=24.2424242424242, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI290463104, Length=199, Percent_Identity=26.1306532663317, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1786904, Length=497, Percent_Identity=26.5593561368209, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1789566, Length=465, Percent_Identity=24.9462365591398, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788361, Length=449, Percent_Identity=22.9398663697105, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17535441, Length=380, Percent_Identity=25, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71993878, Length=278, Percent_Identity=27.3381294964029, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71993870, Length=282, Percent_Identity=27.6595744680851, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323752, Length=496, Percent_Identity=25.8064516129032, Blast_Score=100, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6322722, Length=403, Percent_Identity=25.8064516129032, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6323934, Length=283, Percent_Identity=27.9151943462898, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17864244, Length=378, Percent_Identity=24.0740740740741, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI20129809, Length=421, Percent_Identity=24.2280285035629, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24651977, Length=421, Percent_Identity=24.2280285035629, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 51307; Mature: 51307

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVKFGTDGWRAIIAEEFTFANLKRVTLAAAEYFLNQPDSLRGICLGYDTRFMSADFARY
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHH
SAEIFSSKGLRVFLSDSFVPTPAVSLYTKEKKLAGGVVITASHNPPVYNGFKIKDSYGGS
HHHHHCCCCCEEEEECCCCCCCCEEEEECCHHHCCCEEEEECCCCCCCCCEEEECCCCCC
AHPQSIAIIEENLEHVDAEEPIVPNEHLIELTDIKEFYLQNLSRNIDLKSIHDTQMTIAH
CCCCEEEEEEHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCEEECCCEEEEEH
NAMFGAGQQIISGLFDESTVSNYHCSLNPGFMGINPEPVAQNVMDFVDFVKEVKTDVAII
HHHHCCHHHHHHHHHCCCCCCCEEEECCCCEECCCCCHHHHHHHHHHHHHHHHCCCEEEE
NDGDADRVGMLDENGSFIDSHKIFAIVLKYLVEDRGEKGEIAKTFALTDVIDSICRKHDL
ECCCCCCCCEECCCCCEECHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC
PLHILPVGFKHVSKLMTTSNILMGGEESGGIGITSYLPERDGIYIGLLVLEIMAKKKMTL
CEEEEECCHHHHHHHHHHHHEEECCCCCCCEEEEECCCCCCCEEHHHHHHHHHHHCCCHH
GELVKELFDEYGYFYYERHDLHVSQEKKQAIMRRAAGGDITAIGPYPVTRFNDLDGYKYH
HHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCEECCCCCEEEE
FKGGWLLIRPSGTEPVLRIYCEADSREKAQKALAFAEKIA
EECCEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQVKFGTDGWRAIIAEEFTFANLKRVTLAAAEYFLNQPDSLRGICLGYDTRFMSADFARY
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHH
SAEIFSSKGLRVFLSDSFVPTPAVSLYTKEKKLAGGVVITASHNPPVYNGFKIKDSYGGS
HHHHHCCCCCEEEEECCCCCCCCEEEEECCHHHCCCEEEEECCCCCCCCCEEEECCCCCC
AHPQSIAIIEENLEHVDAEEPIVPNEHLIELTDIKEFYLQNLSRNIDLKSIHDTQMTIAH
CCCCEEEEEEHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCEEECCCEEEEEH
NAMFGAGQQIISGLFDESTVSNYHCSLNPGFMGINPEPVAQNVMDFVDFVKEVKTDVAII
HHHHCCHHHHHHHHHCCCCCCCEEEECCCCEECCCCCHHHHHHHHHHHHHHHHCCCEEEE
NDGDADRVGMLDENGSFIDSHKIFAIVLKYLVEDRGEKGEIAKTFALTDVIDSICRKHDL
ECCCCCCCCEECCCCCEECHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC
PLHILPVGFKHVSKLMTTSNILMGGEESGGIGITSYLPERDGIYIGLLVLEIMAKKKMTL
CEEEEECCHHHHHHHHHHHHEEECCCCCCCEEEEECCCCCCCEEHHHHHHHHHHHCCCHH
GELVKELFDEYGYFYYERHDLHVSQEKKQAIMRRAAGGDITAIGPYPVTRFNDLDGYKYH
HHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCEECCCCCEEEE
FKGGWLLIRPSGTEPVLRIYCEADSREKAQKALAFAEKIA
EECCEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA