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The map label for this gene is idsA [H]

Identifier: 194333227

GI number: 194333227

Start: 414831

End: 415844

Strand: Reverse

Name: idsA [H]

Synonym: Paes_0383

Alternate gene names: 194333227

Gene position: 415844-414831 (Counterclockwise)

Preceding gene: 194333228

Following gene: 194333226

Centisome position: 16.55

GC content: 50.2

Gene sequence:

>1014_bases
ATGGCTAGTTCAGCAATACAGATCGGTCTGACTCAGGATCAGGTAGAAACCAAATACAAAGAGTACCACAAGCGAATCAA
CGATGCGCTTGCCGGATGCTTTACCAAAAGCACACCGGAGACACTCTACGCTCCGGCTCGCTATATTCTTGAAGGCAAAG
GCAAACGCATCAGGCCGTTTCTTACCCTGTTGGCTGCCGAATCAGTCTGCAACTCATCAGATGATGCCCTCAATGCCGCT
CTCGGCGTCGAAATTCTTCATAATTTTACCCTGATGCATGACGACATCATGGATCAGGCCGATCTGCGGCATGGACGACC
GACCGTTCACCTCAAATGGGATGAAAATGCCGCGATACTCTCAGGCGATATGATGATCGCATTCGCCTATGAATGCGCAC
TGAATACAAAAACAGATCGTCACGCCGAGCTTGTCCATATTCTCAACGACGCCAATATCACGATCTGCGAAGGTCAGGCT
CTTGATATGGAGCTTGAACAACGCGCTGAAGCGACTATAGCAGATTATCTGGACATGATTTCAAAAAAAACCGGCCGTCT
GATCTCTGCCGCCCTCGAGGCCGGGGGAGTCGTCGGCAATGCTGATGCTCTGCAGCTGCAGGCGCTGGTAACATTCGGCG
AAAAAATCGGCAGAGCGTTCCAGGTCCAGGATGACTATCTCGATATCATGGCCGATGACGGTAAATCAGGAAAAATACCC
GGTGGAGATGTCATCAACGGCAAGAAAACCTATCTGCTCCTGCGTTCCATCGAACTGACCGAGGGCAATGAACGTAAACT
CCTTCAGAGCATTATCGCCAATAAAGGCATAGAGCCTGAGCGCGTCCCCGAAATCAGAGCTATATTTGAACAGTGCGGTG
TACTTGAAGAAGCACGGCAGCTTATCAACCGCGATACTGAAGAAGCGCTTTCAGCAATCGATCCGTTGCCCTTTGGCGAA
GGACGGGATCACCTCAAGGGATTTGCCCTGAAACTCATGAAAAGGGATTTCTAA

Upstream 100 bases:

>100_bases
CAAACGATCCTTACCTGGATGAATGATCTGAAAGCGGCTATGTTTCTTACCGGATCACGAACCATAAGGGATTTACAACA
AACCAGGACCATTATACACC

Downstream 100 bases:

>100_bases
ACATCTTTACCCCCACTGCCCGTGATGCTCTCCCCCGGCATCGAAAAAAATGATCTTGACGATCTTCTCATCCTGCTGGT
TCTATCCGGAATTGAAGGAA

Product: polyprenyl synthetase

Products: NA

Alternate protein names: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl pyrophosphate synthase; FPP synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MASSAIQIGLTQDQVETKYKEYHKRINDALAGCFTKSTPETLYAPARYILEGKGKRIRPFLTLLAAESVCNSSDDALNAA
LGVEILHNFTLMHDDIMDQADLRHGRPTVHLKWDENAAILSGDMMIAFAYECALNTKTDRHAELVHILNDANITICEGQA
LDMELEQRAEATIADYLDMISKKTGRLISAALEAGGVVGNADALQLQALVTFGEKIGRAFQVQDDYLDIMADDGKSGKIP
GGDVINGKKTYLLLRSIELTEGNERKLLQSIIANKGIEPERVPEIRAIFEQCGVLEEARQLINRDTEEALSAIDPLPFGE
GRDHLKGFALKLMKRDF

Sequences:

>Translated_337_residues
MASSAIQIGLTQDQVETKYKEYHKRINDALAGCFTKSTPETLYAPARYILEGKGKRIRPFLTLLAAESVCNSSDDALNAA
LGVEILHNFTLMHDDIMDQADLRHGRPTVHLKWDENAAILSGDMMIAFAYECALNTKTDRHAELVHILNDANITICEGQA
LDMELEQRAEATIADYLDMISKKTGRLISAALEAGGVVGNADALQLQALVTFGEKIGRAFQVQDDYLDIMADDGKSGKIP
GGDVINGKKTYLLLRSIELTEGNERKLLQSIIANKGIEPERVPEIRAIFEQCGVLEEARQLINRDTEEALSAIDPLPFGE
GRDHLKGFALKLMKRDF
>Mature_336_residues
ASSAIQIGLTQDQVETKYKEYHKRINDALAGCFTKSTPETLYAPARYILEGKGKRIRPFLTLLAAESVCNSSDDALNAAL
GVEILHNFTLMHDDIMDQADLRHGRPTVHLKWDENAAILSGDMMIAFAYECALNTKTDRHAELVHILNDANITICEGQAL
DMELEQRAEATIADYLDMISKKTGRLISAALEAGGVVGNADALQLQALVTFGEKIGRAFQVQDDYLDIMADDGKSGKIPG
GDVINGKKTYLLLRSIELTEGNERKLLQSIIANKGIEPERVPEIRAIFEQCGVLEEARQLINRDTEEALSAIDPLPFGEG
RDHLKGFALKLMKRDF

Specific function: Supplies Octaprenyl Diphosphate, The Precursor For The Side Chain Of The Isoprenoid Quinones Ubiquinone And Menaquinone. [C]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=302, Percent_Identity=27.1523178807947, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1789578, Length=289, Percent_Identity=29.757785467128, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786623, Length=268, Percent_Identity=33.2089552238806, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17505681, Length=325, Percent_Identity=24, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17508563, Length=279, Percent_Identity=27.2401433691756, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6325188, Length=223, Percent_Identity=29.5964125560538, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24651612, Length=309, Percent_Identity=26.8608414239482, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI17137582, Length=258, Percent_Identity=26.3565891472868, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.1; =2.5.1.10 [H]

Molecular weight: Translated: 37217; Mature: 37086

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSAIQIGLTQDQVETKYKEYHKRINDALAGCFTKSTPETLYAPARYILEGKGKRIRPF
CCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHH
LTLLAAESVCNSSDDALNAALGVEILHNFTLMHDDIMDQADLRHGRPTVHLKWDENAAIL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEE
SGDMMIAFAYECALNTKTDRHAELVHILNDANITICEGQALDMELEQRAEATIADYLDMI
ECCEEEEEEEEHHCCCCCCHHHHHHHEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
SKKTGRLISAALEAGGVVGNADALQLQALVTFGEKIGRAFQVQDDYLDIMADDGKSGKIP
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCEEEEECCCCCCCCC
GGDVINGKKTYLLLRSIELTEGNERKLLQSIIANKGIEPERVPEIRAIFEQCGVLEEARQ
CCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHH
LINRDTEEALSAIDPLPFGEGRDHLKGFALKLMKRDF
HHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ASSAIQIGLTQDQVETKYKEYHKRINDALAGCFTKSTPETLYAPARYILEGKGKRIRPF
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHH
LTLLAAESVCNSSDDALNAALGVEILHNFTLMHDDIMDQADLRHGRPTVHLKWDENAAIL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEE
SGDMMIAFAYECALNTKTDRHAELVHILNDANITICEGQALDMELEQRAEATIADYLDMI
ECCEEEEEEEEHHCCCCCCHHHHHHHEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
SKKTGRLISAALEAGGVVGNADALQLQALVTFGEKIGRAFQVQDDYLDIMADDGKSGKIP
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCEEEEECCCCCCCCC
GGDVINGKKTYLLLRSIELTEGNERKLLQSIIANKGIEPERVPEIRAIFEQCGVLEEARQ
CCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHH
LINRDTEEALSAIDPLPFGEGRDHLKGFALKLMKRDF
HHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]