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The map label for this gene is mpg1 [H]

Identifier: 194333078

GI number: 194333078

Start: 245148

End: 246107

Strand: Reverse

Name: mpg1 [H]

Synonym: Paes_0234

Alternate gene names: 194333078

Gene position: 246107-245148 (Counterclockwise)

Preceding gene: 194333079

Following gene: 194333077

Centisome position: 9.79

GC content: 50.83

Gene sequence:

>960_bases
ATGAAAGCCTTCGTTCTCGCTGCCGGCTTCGGAACACGACTCAGACCGCTGACCGTCAGCATACCCAAACCACTGATACC
CGTCCTGAACATTCCCTCGCTGTGCTACACGCTCTTCCTTCTCAAAGAAGCGGGCATCAGGGACATCGTCTGCAACCTGC
ACTATCATGCAGATGCCATCGTCAGATATCTCGAAGAGCAGGATTTTTTCGGCATGAATATCATGATCTCGGAGGAAAAA
GAGATCCTCGGTACCGGAGGAGGTCTGAAAAAATGCGAATCATTGCTCAAGGATGATGATTTTGTCCTGATCAACAGCGA
TATTATTACTGATATCAGCCTCGATGCGCTCATCAAGGCCTACCGCAGGAGCGACGCGTCAGGAGTACTCATGCTTCATG
AAACCCCCCAGGCTGGAGCTATTGGCCATATTGGTGTTCAGAACGGAATGGTCAAGGATTTCAGGAACATGCGAAGAACG
GAACTCCGATCAGACCTTATTTATACAGGAACCGCCGTTCTCAGCCCGGATATCTTCAATCATCTGCAAACAGGGTTTTC
AAGCATTGTCGACACGGGCTTTACAGGCCTTATCGATAACGGCGGGGTGGCATCATATGTACATGACGGACTCTGGCAGG
ATATCGGTACACTTGAAGAGTACCTCTACAGCTCAACACACAAAAACAGACCGGTTCTGGAGCTTGGCAACCGTATGCAG
AACGCTCTCGGAATCAGGCCGCATATGCTTGCCGACGATGCCCGAATCAGTCCGGAAGCAACCGTTACATCATCGGTTAT
CGGTAAAGGTTGCCAGGTCGGCCCTGGCGCAATCATAGAGAACGCTCTACTCCTGCCCGGCGTCTCGATCGATGAACGAC
AGATCGTCAGCAACAGCATCGTCTATACAGAAGGAATCATTACTCTCAACCAGGTAATCACGGAGAACCCCGGCTCATGA

Upstream 100 bases:

>100_bases
TTGAACCCACAATCGCCTATCTTCCCGACTATATAAACCGGCATGCCGAACTCAAAACAGCAGGCAGAATCATCATGGAA
ACTCTGGCACCATCTTTATC

Downstream 100 bases:

>100_bases
TCGCTACCGGACTGGACCTGCTGCTGCAGGACACCTCGGCACTCAAAGGAAAAAACATTGCCCTGATTGCCAATCAGACA
TCCGTCACCCGAGATCTCGA

Product: Nucleotidyl transferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MKAFVLAAGFGTRLRPLTVSIPKPLIPVLNIPSLCYTLFLLKEAGIRDIVCNLHYHADAIVRYLEEQDFFGMNIMISEEK
EILGTGGGLKKCESLLKDDDFVLINSDIITDISLDALIKAYRRSDASGVLMLHETPQAGAIGHIGVQNGMVKDFRNMRRT
ELRSDLIYTGTAVLSPDIFNHLQTGFSSIVDTGFTGLIDNGGVASYVHDGLWQDIGTLEEYLYSSTHKNRPVLELGNRMQ
NALGIRPHMLADDARISPEATVTSSVIGKGCQVGPGAIIENALLLPGVSIDERQIVSNSIVYTEGIITLNQVITENPGS

Sequences:

>Translated_319_residues
MKAFVLAAGFGTRLRPLTVSIPKPLIPVLNIPSLCYTLFLLKEAGIRDIVCNLHYHADAIVRYLEEQDFFGMNIMISEEK
EILGTGGGLKKCESLLKDDDFVLINSDIITDISLDALIKAYRRSDASGVLMLHETPQAGAIGHIGVQNGMVKDFRNMRRT
ELRSDLIYTGTAVLSPDIFNHLQTGFSSIVDTGFTGLIDNGGVASYVHDGLWQDIGTLEEYLYSSTHKNRPVLELGNRMQ
NALGIRPHMLADDARISPEATVTSSVIGKGCQVGPGAIIENALLLPGVSIDERQIVSNSIVYTEGIITLNQVITENPGS
>Mature_319_residues
MKAFVLAAGFGTRLRPLTVSIPKPLIPVLNIPSLCYTLFLLKEAGIRDIVCNLHYHADAIVRYLEEQDFFGMNIMISEEK
EILGTGGGLKKCESLLKDDDFVLINSDIITDISLDALIKAYRRSDASGVLMLHETPQAGAIGHIGVQNGMVKDFRNMRRT
ELRSDLIYTGTAVLSPDIFNHLQTGFSSIVDTGFTGLIDNGGVASYVHDGLWQDIGTLEEYLYSSTHKNRPVLELGNRMQ
NALGIRPHMLADDARISPEATVTSSVIGKGCQVGPGAIIENALLLPGVSIDERQIVSNSIVYTEGIITLNQVITENPGS

Specific function: Lipopolysaccharide biosynthesis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=302, Percent_Identity=28.1456953642384, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI11761619, Length=317, Percent_Identity=27.4447949526814, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI31881779, Length=344, Percent_Identity=25.5813953488372, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI45447090, Length=344, Percent_Identity=25.5813953488372, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI133931050, Length=320, Percent_Identity=28.4375, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17509979, Length=328, Percent_Identity=25, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6320148, Length=315, Percent_Identity=29.5238095238095, Blast_Score=129, Evalue=7e-31,
Organism=Drosophila melanogaster, GI21355443, Length=312, Percent_Identity=27.8846153846154, Blast_Score=121, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24644084, Length=312, Percent_Identity=27.8846153846154, Blast_Score=121, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 34756; Mature: 34756

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAFVLAAGFGTRLRPLTVSIPKPLIPVLNIPSLCYTLFLLKEAGIRDIVCNLHYHADAI
CCEEEEEECCCCCCCEEEEECCCCCHHHCCCHHHHHHHHHHHHCCHHHHHEECHHHHHHH
VRYLEEQDFFGMNIMISEEKEILGTGGGLKKCESLLKDDDFVLINSDIITDISLDALIKA
HHHHHHCCCCCEEEEEECCHHHHCCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHH
YRRSDASGVLMLHETPQAGAIGHIGVQNGMVKDFRNMRRTELRSDLIYTGTAVLSPDIFN
HHCCCCCCEEEEECCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHEEECHHHCCHHHHH
HLQTGFSSIVDTGFTGLIDNGGVASYVHDGLWQDIGTLEEYLYSSTHKNRPVLELGNRMQ
HHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
NALGIRPHMLADDARISPEATVTSSVIGKGCQVGPGAIIENALLLPGVSIDERQIVSNSI
HHHCCCCCEECCCCCCCCCHHHHHHHHCCCCCCCCCHHHHCHHCCCCCCCCHHHHHHCCE
VYTEGIITLNQVITENPGS
EEECCHHHHHHHHHCCCCC
>Mature Secondary Structure
MKAFVLAAGFGTRLRPLTVSIPKPLIPVLNIPSLCYTLFLLKEAGIRDIVCNLHYHADAI
CCEEEEEECCCCCCCEEEEECCCCCHHHCCCHHHHHHHHHHHHCCHHHHHEECHHHHHHH
VRYLEEQDFFGMNIMISEEKEILGTGGGLKKCESLLKDDDFVLINSDIITDISLDALIKA
HHHHHHCCCCCEEEEEECCHHHHCCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHH
YRRSDASGVLMLHETPQAGAIGHIGVQNGMVKDFRNMRRTELRSDLIYTGTAVLSPDIFN
HHCCCCCCEEEEECCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHEEECHHHCCHHHHH
HLQTGFSSIVDTGFTGLIDNGGVASYVHDGLWQDIGTLEEYLYSSTHKNRPVLELGNRMQ
HHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
NALGIRPHMLADDARISPEATVTSSVIGKGCQVGPGAIIENALLLPGVSIDERQIVSNSI
HHHCCCCCEECCCCCCCCCHHHHHHHHCCCCCCCCCHHHHCHHCCCCCCCCHHHHHHCCE
VYTEGIITLNQVITENPGS
EEECCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]