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The map label for this gene is fabH [H]

Identifier: 194333023

GI number: 194333023

Start: 184980

End: 185966

Strand: Reverse

Name: fabH [H]

Synonym: Paes_0177

Alternate gene names: 194333023

Gene position: 185966-184980 (Counterclockwise)

Preceding gene: 194333024

Following gene: 194333022

Centisome position: 7.4

GC content: 50.76

Gene sequence:

>987_bases
ATGAAAGCTGCTATCACTGCGACAGCAAAGTATTTGCCAGACGATATCCTCAGCAATCAGGACCTGGAAAAAATACTTGA
TACAAGTGATGAATGGATACGCACCCGGACGGGCATCAGTGAACGACGAATTCTGAAAGACCCTGAAAAAGCAACGTCCT
TCCTCTGTAGTCAGGTAGCAGAGAGAATCATCGAAAAAAGAGGCATTTCCGCAGAAGAGATCGATCTGATTATCGTTGCG
ACCATGACACCGGACATGATTTTCCCTTCGACCGCATGTCTTGTCCAGAAAAATATCGGTGCATCAAATGCATGGGCTTT
TGACCTCTCAGGCGCATGCTCAGGATTTCTCTTTGCGCTCAATACCGGATCACAGTTCATTGCAGCCGGAACACATCGCA
AGGTTCTTGTTATCGGAGGCGAAAAGATGTCTTCCGTCATGGATTACACCGATCGCAACACCTGTGTTCTTTTCGGCGAC
GGCGCAGCAGGCGTGCTTCTCGAACCGGCAAAAGATGAGAACCACGGCATGCTTGACGCAAAACTTCATGCCGATGGCAG
AGGCGGCGAACACCTCTATATGCAAGGCGGAGGCAGCAGGCACCCGGCAACCCACGAGACGGTAGACGGCCGCATGCACT
ATCTGCACCAGGATGGAAAACAGGTATTCAAGTCTGCTGTCACGGCAATGGCCGACATCGCTGTCGAAATCATGGAGCGC
AACAATCTTGTCGCTGATGATGTCAGCTATCTGATCCCGCACCAGGCCAACAAAAGAATCATTCAGGCAACAGCTGAACG
TATGGGAATCGATATGGCAAAGGTAGCCATCAATATTGACAAGTACGGCAACACGTCGGCAGCCACTATCCCGATCTGCA
TTGCTGAACTTGACGAAGCCAGGAAACTTCAACCGGAAAACAACCTCATCCTCGTCAGCTTCGGTGCCGGGTACACATGG
GGCGGCATCTACCTGAAGTGGCAGTAA

Upstream 100 bases:

>100_bases
GCACAATTGCGCTCCTTCGACATGCCGGAAATCATAAGCCCCTGGTTTATAACCCTACAATGCGGGAAATCCCCTGCATC
GACATAAACGTCAATTTATT

Downstream 100 bases:

>100_bases
CAGGAACATTTACAGAAGAAACAGAAGACAGAGTTTCATGAAAGCATTTGTATTTCCCGGCCAGGGATCACAGTACTGTG
GCATGGCAAAAGATATCTAC

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MKAAITATAKYLPDDILSNQDLEKILDTSDEWIRTRTGISERRILKDPEKATSFLCSQVAERIIEKRGISAEEIDLIIVA
TMTPDMIFPSTACLVQKNIGASNAWAFDLSGACSGFLFALNTGSQFIAAGTHRKVLVIGGEKMSSVMDYTDRNTCVLFGD
GAAGVLLEPAKDENHGMLDAKLHADGRGGEHLYMQGGGSRHPATHETVDGRMHYLHQDGKQVFKSAVTAMADIAVEIMER
NNLVADDVSYLIPHQANKRIIQATAERMGIDMAKVAINIDKYGNTSAATIPICIAELDEARKLQPENNLILVSFGAGYTW
GGIYLKWQ

Sequences:

>Translated_328_residues
MKAAITATAKYLPDDILSNQDLEKILDTSDEWIRTRTGISERRILKDPEKATSFLCSQVAERIIEKRGISAEEIDLIIVA
TMTPDMIFPSTACLVQKNIGASNAWAFDLSGACSGFLFALNTGSQFIAAGTHRKVLVIGGEKMSSVMDYTDRNTCVLFGD
GAAGVLLEPAKDENHGMLDAKLHADGRGGEHLYMQGGGSRHPATHETVDGRMHYLHQDGKQVFKSAVTAMADIAVEIMER
NNLVADDVSYLIPHQANKRIIQATAERMGIDMAKVAINIDKYGNTSAATIPICIAELDEARKLQPENNLILVSFGAGYTW
GGIYLKWQ
>Mature_328_residues
MKAAITATAKYLPDDILSNQDLEKILDTSDEWIRTRTGISERRILKDPEKATSFLCSQVAERIIEKRGISAEEIDLIIVA
TMTPDMIFPSTACLVQKNIGASNAWAFDLSGACSGFLFALNTGSQFIAAGTHRKVLVIGGEKMSSVMDYTDRNTCVLFGD
GAAGVLLEPAKDENHGMLDAKLHADGRGGEHLYMQGGGSRHPATHETVDGRMHYLHQDGKQVFKSAVTAMADIAVEIMER
NNLVADDVSYLIPHQANKRIIQATAERMGIDMAKVAINIDKYGNTSAATIPICIAELDEARKLQPENNLILVSFGAGYTW
GGIYLKWQ

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=327, Percent_Identity=40.0611620795107, Blast_Score=251, Evalue=5e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 35804; Mature: 35804

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAITATAKYLPDDILSNQDLEKILDTSDEWIRTRTGISERRILKDPEKATSFLCSQVA
CCCEEEHHHHHCCHHHCCCCCHHHHHCCCHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHH
ERIIEKRGISAEEIDLIIVATMTPDMIFPSTACLVQKNIGASNAWAFDLSGACSGFLFAL
HHHHHHCCCCHHHEEEEEEEECCCCCCCCCHHEEEECCCCCCCCEEEECCCCCCEEEEEE
NTGSQFIAAGTHRKVLVIGGEKMSSVMDYTDRNTCVLFGDGAAGVLLEPAKDENHGMLDA
ECCCEEEEECCCCEEEEECCHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCCCCCEEEE
KLHADGRGGEHLYMQGGGSRHPATHETVDGRMHYLHQDGKQVFKSAVTAMADIAVEIMER
EEECCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NNLVADDVSYLIPHQANKRIIQATAERMGIDMAKVAINIDKYGNTSAATIPICIAELDEA
CCCCCCCHHHHCCCCCCHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCEEEEEEEHHHHH
RKLQPENNLILVSFGAGYTWGGIYLKWQ
HCCCCCCCEEEEEECCCCEECEEEEEEC
>Mature Secondary Structure
MKAAITATAKYLPDDILSNQDLEKILDTSDEWIRTRTGISERRILKDPEKATSFLCSQVA
CCCEEEHHHHHCCHHHCCCCCHHHHHCCCHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHH
ERIIEKRGISAEEIDLIIVATMTPDMIFPSTACLVQKNIGASNAWAFDLSGACSGFLFAL
HHHHHHCCCCHHHEEEEEEEECCCCCCCCCHHEEEECCCCCCCCEEEECCCCCCEEEEEE
NTGSQFIAAGTHRKVLVIGGEKMSSVMDYTDRNTCVLFGDGAAGVLLEPAKDENHGMLDA
ECCCEEEEECCCCEEEEECCHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCCCCCEEEE
KLHADGRGGEHLYMQGGGSRHPATHETVDGRMHYLHQDGKQVFKSAVTAMADIAVEIMER
EEECCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NNLVADDVSYLIPHQANKRIIQATAERMGIDMAKVAINIDKYGNTSAATIPICIAELDEA
CCCCCCCHHHHCCCCCCHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCEEEEEEEHHHHH
RKLQPENNLILVSFGAGYTWGGIYLKWQ
HCCCCCCCEEEEEECCCCEECEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA