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The map label for this gene is fabD [H]

Identifier: 194333022

GI number: 194333022

Start: 184028

End: 184942

Strand: Reverse

Name: fabD [H]

Synonym: Paes_0176

Alternate gene names: 194333022

Gene position: 184942-184028 (Counterclockwise)

Preceding gene: 194333023

Following gene: 194333021

Centisome position: 7.36

GC content: 53.66

Gene sequence:

>915_bases
ATGAAAGCATTTGTATTTCCCGGCCAGGGATCACAGTACTGTGGCATGGCAAAAGATATCTACAACGCATTCCCTCAGGC
AAAGGCCGTGATGGACAAGGCGAACGACATTCTCGGCTACAGCATCACCGATATCATGTTCGATGCGCCGGAAGAAGAAT
TACGCAAAACGCAGTACACTCAGCCGGCCATCTTCCTTCACAGCATTGCCGTCGCAGAACTGCTGGGAAAAGAAGGCGTC
GACATGGCTGCCGGCCACAGCCTCGGCGAATACACAGCGCTCTGTTTTGCCGGAGCCATGAGCTTTGAAGATGCCATGAA
GATTGTTGCCCGCCGTGGAGAACTCATGCAGCATGCAGGCACCCGGAACCCCGGCTCCATGGCTGCCATTATCGGCATGA
AAGATGATGTCCTTGACGAGCTTCTCAAAGAGGCCGGTGAAACAGGAATCGTCCAGGCCGCAAACTTCAACTCGCCAGGC
CAGATCGTCATTTCAGGAGAGATCAGCGCGGTAAAAAAAGCTGTTGAACTGGCACCGTTGAAAGGGGCTAGAATGGCAAA
AGAGCTTCCCGTCTCAGGAGCGTTCCATTCCCCGCTGATGAAGCCTGCAGAAGAGGAACTCAAAGCAGCACTCGACGCGA
TCACCATTCATGACGCGGCAATTCCGGTATGCATGAATGTCACTGCAGAGCCGGTTTGCAAGGCAGCCGATATCCGCAAC
AACCTTGTCCTTCAGTTGACAAGCCCGGTTCGCTGGACCCAGTCGGTCGAAACAATGATCGCAGGAGGCGTCACCCTCTT
CAGCGAAATCGGACCGCAGAAAGTCCTGCAGGGGCTAATCAAAAGAATCGACCGGAACGTCACTATCCAGGGTATCGACA
ACGCTGAACAGATTCAACAGCAGCTGTCACTCTAA

Upstream 100 bases:

>100_bases
CTCATCCTCGTCAGCTTCGGTGCCGGGTACACATGGGGCGGCATCTACCTGAAGTGGCAGTAACAGGAACATTTACAGAA
GAAACAGAAGACAGAGTTTC

Downstream 100 bases:

>100_bases
CCCAATTTTTCAACGATGTTATTTAAACACCATACTATGAGCATGTTTGAAGGCAAAACCGCCGTCATCACCGGCGCTGC
ACGAGGTATCGGCCAGGCTA

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MKAFVFPGQGSQYCGMAKDIYNAFPQAKAVMDKANDILGYSITDIMFDAPEEELRKTQYTQPAIFLHSIAVAELLGKEGV
DMAAGHSLGEYTALCFAGAMSFEDAMKIVARRGELMQHAGTRNPGSMAAIIGMKDDVLDELLKEAGETGIVQAANFNSPG
QIVISGEISAVKKAVELAPLKGARMAKELPVSGAFHSPLMKPAEEELKAALDAITIHDAAIPVCMNVTAEPVCKAADIRN
NLVLQLTSPVRWTQSVETMIAGGVTLFSEIGPQKVLQGLIKRIDRNVTIQGIDNAEQIQQQLSL

Sequences:

>Translated_304_residues
MKAFVFPGQGSQYCGMAKDIYNAFPQAKAVMDKANDILGYSITDIMFDAPEEELRKTQYTQPAIFLHSIAVAELLGKEGV
DMAAGHSLGEYTALCFAGAMSFEDAMKIVARRGELMQHAGTRNPGSMAAIIGMKDDVLDELLKEAGETGIVQAANFNSPG
QIVISGEISAVKKAVELAPLKGARMAKELPVSGAFHSPLMKPAEEELKAALDAITIHDAAIPVCMNVTAEPVCKAADIRN
NLVLQLTSPVRWTQSVETMIAGGVTLFSEIGPQKVLQGLIKRIDRNVTIQGIDNAEQIQQQLSL
>Mature_304_residues
MKAFVFPGQGSQYCGMAKDIYNAFPQAKAVMDKANDILGYSITDIMFDAPEEELRKTQYTQPAIFLHSIAVAELLGKEGV
DMAAGHSLGEYTALCFAGAMSFEDAMKIVARRGELMQHAGTRNPGSMAAIIGMKDDVLDELLKEAGETGIVQAANFNSPG
QIVISGEISAVKKAVELAPLKGARMAKELPVSGAFHSPLMKPAEEELKAALDAITIHDAAIPVCMNVTAEPVCKAADIRN
NLVLQLTSPVRWTQSVETMIAGGVTLFSEIGPQKVLQGLIKRIDRNVTIQGIDNAEQIQQQLSL

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=299, Percent_Identity=33.7792642140468, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI27477045, Length=111, Percent_Identity=38.7387387387387, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1787334, Length=305, Percent_Identity=42.6229508196721, Blast_Score=218, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI71984332, Length=271, Percent_Identity=31.7343173431734, Blast_Score=133, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI17550940, Length=287, Percent_Identity=29.9651567944251, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24665753, Length=298, Percent_Identity=34.5637583892617, Blast_Score=155, Evalue=5e-38,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32617; Mature: 32617

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAFVFPGQGSQYCGMAKDIYNAFPQAKAVMDKANDILGYSITDIMFDAPEEELRKTQYT
CCEEEECCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHCCC
QPAIFLHSIAVAELLGKEGVDMAAGHSLGEYTALCFAGAMSFEDAMKIVARRGELMQHAG
CHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
TRNPGSMAAIIGMKDDVLDELLKEAGETGIVQAANFNSPGQIVISGEISAVKKAVELAPL
CCCCCCEEEEECCCHHHHHHHHHHCCCCCEEEECCCCCCCCEEEECCHHHHHHHHHHCCC
KGARMAKELPVSGAFHSPLMKPAEEELKAALDAITIHDAAIPVCMNVTAEPVCKAADIRN
CCHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
NLVLQLTSPVRWTQSVETMIAGGVTLFSEIGPQKVLQGLIKRIDRNVTIQGIDNAEQIQQ
CEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCHHHHHH
QLSL
HHCC
>Mature Secondary Structure
MKAFVFPGQGSQYCGMAKDIYNAFPQAKAVMDKANDILGYSITDIMFDAPEEELRKTQYT
CCEEEECCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHCCC
QPAIFLHSIAVAELLGKEGVDMAAGHSLGEYTALCFAGAMSFEDAMKIVARRGELMQHAG
CHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
TRNPGSMAAIIGMKDDVLDELLKEAGETGIVQAANFNSPGQIVISGEISAVKKAVELAPL
CCCCCCEEEEECCCHHHHHHHHHHCCCCCEEEECCCCCCCCEEEECCHHHHHHHHHHCCC
KGARMAKELPVSGAFHSPLMKPAEEELKAALDAITIHDAAIPVCMNVTAEPVCKAADIRN
CCHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
NLVLQLTSPVRWTQSVETMIAGGVTLFSEIGPQKVLQGLIKRIDRNVTIQGIDNAEQIQQ
CEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCHHHHHH
QLSL
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]