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The map label for this gene is 194332962

Identifier: 194332962

GI number: 194332962

Start: 119281

End: 120495

Strand: Reverse

Name: 194332962

Synonym: Paes_0115

Alternate gene names: NA

Gene position: 120495-119281 (Counterclockwise)

Preceding gene: 194332963

Following gene: 194332961

Centisome position: 4.8

GC content: 50.86

Gene sequence:

>1215_bases
ATGAGAAACATTGTATTTACAGGAAAAGGGGGCGTCGGAAAAACAACCATTGCCGCCGCCACAGCGCTTAAAGCAGCAGG
AATGGGCTATAAGACACTAGTCATTTCGACCGATCCCGCCCACAGTCTCGGAGACTCCTTCGATATTGATCTCGGCTCGG
CTCCGGTTAAAATCGCTGATAACCTCTACGGACAGGAGGTCAGCGTTTACGGAGACCTGAGCCTCAACTGGGAGGTGGTG
CGACAACATTTCGCTCATCTGATGGAGGTTCAGGGCATCAAGGGAATCTACGTCGAAGAGATGGGCGTCCTGCCGGGCAT
GGAAGAACTCTTCTCCCTCTCCTATATCAAGAAGTACAATGAATCGAAAGAATACGACCTGCTGGTCATCGACTGCGCCC
CGACAGGAGAAACCCTTCGTCTCCTCTCCATTCCGGAAACGTTCGGATGGATGCTCAAGCTCATGAGAAACATGGAAAAA
TATGTCGTCAAACCTGTCATACGACCCATATCCAAACGCGTTGGAAAACTCAGGGAACTGGTCCCGGATGAAGCTGTCTA
TGACCAGGTCGACAACCTCTTCTCGTCAATAGACGGCATTATCGAGCTCCTCTCAGACTCAAGCAAAACAACGGTACGCC
TTGTCATGAACCCGGAAAAGATGGTGATCAAAGAGTCCATGCGAGCGCTGACCTACCTCAATCTCTATGGGATCACCGTC
GATCAGATCGTCATCAACCGCGTCATGACGGATGCTGTCGACGGAGAATACCTGAAAGAATGGAAAGAGATCCAGAAACT
CTACATCGACCAGATCGAGAAGTCATTTTCCCCGATTCCTATCACTCAGGTCCCTCTGTTGCGCAAGGAAGTCTTCGGCC
TTGAAATGCTCTGCCAGGTCGGCGACATCATCTACGATACCTCCGACCCGACGGAGATTCTCTACCGTGAAGAGCATGTC
GATATTCAGAAGAAAAGCGACGGGCACTATGTGATGAAACTGCGTTTACCGTTTGTATTCGACAACAAAATGGAAGCCAA
CATCGTACAGGTTGGTGAGCTCATGACGGTCCGGCTCGGCAATTACCAGAAAGGCGTCGTGCTCCCCGCGTTTCTGGCCG
GTCTGCGCGTCAGCAGCGCCGACTATGAGGACAAATGGCTTGTCATCAACTTTACAACGAAAGAGGAAACATCTGCATCT
CCAGAAAGAGGATGA

Upstream 100 bases:

>100_bases
CTATGGCCTCTGAATGACCGGATAGCTCTTCACAGAATTTTCAACGCCTGTCAACCGTTCTAGTAAAAGGTTCGGCACGA
TCAATGTAACAGGGGCGAAC

Downstream 100 bases:

>100_bases
GTATACACAATGCAGAGAAACACGTCAAAACTGAACAAAGACATTGTAAAGAAAAGTTAATATAACGCATAAAAGACTAT
TAAAAATAGACTTATAACAA

Product: arsenite-activated ATPase ArsA

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MRNIVFTGKGGVGKTTIAAATALKAAGMGYKTLVISTDPAHSLGDSFDIDLGSAPVKIADNLYGQEVSVYGDLSLNWEVV
RQHFAHLMEVQGIKGIYVEEMGVLPGMEELFSLSYIKKYNESKEYDLLVIDCAPTGETLRLLSIPETFGWMLKLMRNMEK
YVVKPVIRPISKRVGKLRELVPDEAVYDQVDNLFSSIDGIIELLSDSSKTTVRLVMNPEKMVIKESMRALTYLNLYGITV
DQIVINRVMTDAVDGEYLKEWKEIQKLYIDQIEKSFSPIPITQVPLLRKEVFGLEMLCQVGDIIYDTSDPTEILYREEHV
DIQKKSDGHYVMKLRLPFVFDNKMEANIVQVGELMTVRLGNYQKGVVLPAFLAGLRVSSADYEDKWLVINFTTKEETSAS
PERG

Sequences:

>Translated_404_residues
MRNIVFTGKGGVGKTTIAAATALKAAGMGYKTLVISTDPAHSLGDSFDIDLGSAPVKIADNLYGQEVSVYGDLSLNWEVV
RQHFAHLMEVQGIKGIYVEEMGVLPGMEELFSLSYIKKYNESKEYDLLVIDCAPTGETLRLLSIPETFGWMLKLMRNMEK
YVVKPVIRPISKRVGKLRELVPDEAVYDQVDNLFSSIDGIIELLSDSSKTTVRLVMNPEKMVIKESMRALTYLNLYGITV
DQIVINRVMTDAVDGEYLKEWKEIQKLYIDQIEKSFSPIPITQVPLLRKEVFGLEMLCQVGDIIYDTSDPTEILYREEHV
DIQKKSDGHYVMKLRLPFVFDNKMEANIVQVGELMTVRLGNYQKGVVLPAFLAGLRVSSADYEDKWLVINFTTKEETSAS
PERG
>Mature_404_residues
MRNIVFTGKGGVGKTTIAAATALKAAGMGYKTLVISTDPAHSLGDSFDIDLGSAPVKIADNLYGQEVSVYGDLSLNWEVV
RQHFAHLMEVQGIKGIYVEEMGVLPGMEELFSLSYIKKYNESKEYDLLVIDCAPTGETLRLLSIPETFGWMLKLMRNMEK
YVVKPVIRPISKRVGKLRELVPDEAVYDQVDNLFSSIDGIIELLSDSSKTTVRLVMNPEKMVIKESMRALTYLNLYGITV
DQIVINRVMTDAVDGEYLKEWKEIQKLYIDQIEKSFSPIPITQVPLLRKEVFGLEMLCQVGDIIYDTSDPTEILYREEHV
DIQKKSDGHYVMKLRLPFVFDNKMEANIVQVGELMTVRLGNYQKGVVLPAFLAGLRVSSADYEDKWLVINFTTKEETSAS
PERG

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=266, Percent_Identity=28.9473684210526, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17557003, Length=314, Percent_Identity=24.5222929936306, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320103, Length=320, Percent_Identity=25.625, Blast_Score=89, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24586297, Length=289, Percent_Identity=28.0276816608997, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003348 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 45519; Mature: 45519

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNIVFTGKGGVGKTTIAAATALKAAGMGYKTLVISTDPAHSLGDSFDIDLGSAPVKIAD
CCCEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHCCCCCCCCCCCCCCHHHH
NLYGQEVSVYGDLSLNWEVVRQHFAHLMEVQGIKGIYVEEMGVLPGMEELFSLSYIKKYN
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEHHHHCCCCCHHHHHHHHHHHHHC
ESKEYDLLVIDCAPTGETLRLLSIPETFGWMLKLMRNMEKYVVKPVIRPISKRVGKLREL
CCCCCEEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPDEAVYDQVDNLFSSIDGIIELLSDSSKTTVRLVMNPEKMVIKESMRALTYLNLYGITV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCHH
DQIVINRVMTDAVDGEYLKEWKEIQKLYIDQIEKSFSPIPITQVPLLRKEVFGLEMLCQV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
GDIIYDTSDPTEILYREEHVDIQKKSDGHYVMKLRLPFVFDNKMEANIVQVGELMTVRLG
HHEEECCCCCHHHHEECCCCCCEECCCCCEEEEEEECEEECCCCCCCHHHHCCEEEEEEC
NYQKGVVLPAFLAGLRVSSADYEDKWLVINFTTKEETSASPERG
CCCCCCHHHHHHHHCEECCCCCCCCEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MRNIVFTGKGGVGKTTIAAATALKAAGMGYKTLVISTDPAHSLGDSFDIDLGSAPVKIAD
CCCEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHCCCCCCCCCCCCCCHHHH
NLYGQEVSVYGDLSLNWEVVRQHFAHLMEVQGIKGIYVEEMGVLPGMEELFSLSYIKKYN
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEHHHHCCCCCHHHHHHHHHHHHHC
ESKEYDLLVIDCAPTGETLRLLSIPETFGWMLKLMRNMEKYVVKPVIRPISKRVGKLREL
CCCCCEEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPDEAVYDQVDNLFSSIDGIIELLSDSSKTTVRLVMNPEKMVIKESMRALTYLNLYGITV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCHH
DQIVINRVMTDAVDGEYLKEWKEIQKLYIDQIEKSFSPIPITQVPLLRKEVFGLEMLCQV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
GDIIYDTSDPTEILYREEHVDIQKKSDGHYVMKLRLPFVFDNKMEANIVQVGELMTVRLG
HHEEECCCCCHHHHEECCCCCCEECCCCCEEEEEEECEEECCCCCCCHHHHCCEEEEEEC
NYQKGVVLPAFLAGLRVSSADYEDKWLVINFTTKEETSASPERG
CCCCCCHHHHHHHHCEECCCCCCCCEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]