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The map label for this gene is gcp

Identifier: 193213610

GI number: 193213610

Start: 2177181

End: 2178236

Strand: Direct

Name: gcp

Synonym: Cpar_1974

Alternate gene names: 193213610

Gene position: 2177181-2178236 (Clockwise)

Preceding gene: 193213606

Following gene: 193213611

Centisome position: 95.1

GC content: 61.84

Gene sequence:

>1056_bases
ATGAACATTTTAGGGATAGAAACCAGTTGTGACGAAACCTCGGCCGCCGTCCTTAGCGACGGAACGGTTCGGTCGAATGT
CGTCAGCTCTCAACGCTGCCACACCGATTTCGGCGGCGTGGTGCCCGAACTGGCTTCACGCGAGCATGAGCGGCTGATCG
TTTCGATTGTCGAAGCCGCCATAACCGAAGCAAATATAGCAAAAAACGACCTCGATGTCATAGCCGCCACCGCCGGCCCG
GGGCTGATCGGTGCGGTAATGGTGGGCCTCTGCTTCGCCGAGGGAATGGCCTTTGCGCTCGGCAAGCCGTTCGTGCCGGT
CAACCACGTCGAAGCGCACATCTTCTCCCCCTTCATCAGCGACGAACCCGGCCATAAATCGCCGGATGGCGACTTTGTTT
CGCTGACTGTTTCGGGCGGGCACACGCTCCTGTCGGTCGTCCGTCAGAATCTCGATTACGAGGTGATCGGCCGCACGATC
GACGACGCGGCGGGCGAGGCGTTCGACAAGACCGGCAAGATGCTTGGCCTCGGCTATCCCGCCGGCCCGGTGATCGACCG
GCTCGCACGCGACGGCGATCCGAAGTTCCACCGCTTCCCGCGCGCACTGACCTCCAGCTCGCAAACCAGCAAAAGCTACC
GCGGCAACTTCGATTTCAGCTTCTCCGGCCTCAAGACCTCGGTGCGCACCTGGCTCGAAGGTCATGACGCGGAGTTCGCC
CGGCAGCATCAAACCGACCTCGCCGCCTCGATTCAGGACGCCATCGTGAGCGTGCTGGTCGAAAAAACTATCGCCGCTGC
GCTGCTGCACAAAGTCGGCGCGGTTTCAGTGGCGGGCGGCGTGAGCGCCAACTCCGGCCTGCGTTCGGCGATGCAGGCGG
CCTGCAACAAGCACGGTCTCGACCTGTTCATTCCCAAAGCGACCTACTCGACCGACAACGCCGCCATGATCGCCACCATG
GCGCAACTGATGATGGCGCGTGGCCGTTACAGGGAAAACTCTTACGGCGTCGCCCCCTTTGCTCGCTTCAAAGCGGCAGG
CAAAGGCACTCGTTGA

Upstream 100 bases:

>100_bases
TCAGGATGAACAACGCCTTTAAAAAGCTGATCTTAACGCGCGGTTTGCTATTCTTCTCCTCTTTCTTACTTTTGGCCATA
AGATTCTCATTCTTTGTGCG

Downstream 100 bases:

>100_bases
AATAGTTCGGGAAATAAATTATCTTGAAAGTCGAAAAAAAGTGCCCGGGAACAGCCGAAACGCTGTCCTGAAGGCCAAGT
CACGATTACCAACCGCAAGC

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MNILGIETSCDETSAAVLSDGTVRSNVVSSQRCHTDFGGVVPELASREHERLIVSIVEAAITEANIAKNDLDVIAATAGP
GLIGAVMVGLCFAEGMAFALGKPFVPVNHVEAHIFSPFISDEPGHKSPDGDFVSLTVSGGHTLLSVVRQNLDYEVIGRTI
DDAAGEAFDKTGKMLGLGYPAGPVIDRLARDGDPKFHRFPRALTSSSQTSKSYRGNFDFSFSGLKTSVRTWLEGHDAEFA
RQHQTDLAASIQDAIVSVLVEKTIAAALLHKVGAVSVAGGVSANSGLRSAMQAACNKHGLDLFIPKATYSTDNAAMIATM
AQLMMARGRYRENSYGVAPFARFKAAGKGTR

Sequences:

>Translated_351_residues
MNILGIETSCDETSAAVLSDGTVRSNVVSSQRCHTDFGGVVPELASREHERLIVSIVEAAITEANIAKNDLDVIAATAGP
GLIGAVMVGLCFAEGMAFALGKPFVPVNHVEAHIFSPFISDEPGHKSPDGDFVSLTVSGGHTLLSVVRQNLDYEVIGRTI
DDAAGEAFDKTGKMLGLGYPAGPVIDRLARDGDPKFHRFPRALTSSSQTSKSYRGNFDFSFSGLKTSVRTWLEGHDAEFA
RQHQTDLAASIQDAIVSVLVEKTIAAALLHKVGAVSVAGGVSANSGLRSAMQAACNKHGLDLFIPKATYSTDNAAMIATM
AQLMMARGRYRENSYGVAPFARFKAAGKGTR
>Mature_351_residues
MNILGIETSCDETSAAVLSDGTVRSNVVSSQRCHTDFGGVVPELASREHERLIVSIVEAAITEANIAKNDLDVIAATAGP
GLIGAVMVGLCFAEGMAFALGKPFVPVNHVEAHIFSPFISDEPGHKSPDGDFVSLTVSGGHTLLSVVRQNLDYEVIGRTI
DDAAGEAFDKTGKMLGLGYPAGPVIDRLARDGDPKFHRFPRALTSSSQTSKSYRGNFDFSFSGLKTSVRTWLEGHDAEFA
RQHQTDLAASIQDAIVSVLVEKTIAAALLHKVGAVSVAGGVSANSGLRSAMQAACNKHGLDLFIPKATYSTDNAAMIATM
AQLMMARGRYRENSYGVAPFARFKAAGKGTR

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=339, Percent_Identity=33.0383480825959, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI8923380, Length=332, Percent_Identity=29.8192771084337, Blast_Score=104, Evalue=2e-22,
Organism=Escherichia coli, GI1789445, Length=320, Percent_Identity=42.5, Blast_Score=247, Evalue=7e-67,
Organism=Caenorhabditis elegans, GI71995670, Length=337, Percent_Identity=30.5637982195846, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17557464, Length=340, Percent_Identity=26.7647058823529, Blast_Score=113, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6320099, Length=338, Percent_Identity=30.1775147928994, Blast_Score=135, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6322891, Length=299, Percent_Identity=26.7558528428094, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI20129063, Length=336, Percent_Identity=31.25, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI21357207, Length=330, Percent_Identity=29.6969696969697, Blast_Score=126, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_CHLP8 (B3QLC5)

Other databases:

- EMBL:   CP001099
- RefSeq:   YP_001999563.1
- MEROPS:   M22.001
- GeneID:   6420926
- GenomeReviews:   CP001099_GR
- KEGG:   cpc:Cpar_1974
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- ProtClustDB:   PRK09604
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 37144; Mature: 37144

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILGIETSCDETSAAVLSDGTVRSNVVSSQRCHTDFGGVVPELASREHERLIVSIVEAA
CCEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCHHCCHHHHHHCHHHHHHHHHHHHHH
ITEANIAKNDLDVIAATAGPGLIGAVMVGLCFAEGMAFALGKPFVPVNHVEAHIFSPFIS
HHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHC
DEPGHKSPDGDFVSLTVSGGHTLLSVVRQNLDYEVIGRTIDDAAGEAFDKTGKMLGLGYP
CCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHCCCEEECCCC
AGPVIDRLARDGDPKFHRFPRALTSSSQTSKSYRGNFDFSFSGLKTSVRTWLEGHDAEFA
CHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHCCCCCEEHHHHHHHHHHHHCCCCHHHH
RQHQTDLAASIQDAIVSVLVEKTIAAALLHKVGAVSVAGGVSANSGLRSAMQAACNKHGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHCCCCC
DLFIPKATYSTDNAAMIATMAQLMMARGRYRENSYGVAPFARFKAAGKGTR
EEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MNILGIETSCDETSAAVLSDGTVRSNVVSSQRCHTDFGGVVPELASREHERLIVSIVEAA
CCEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCHHCCHHHHHHCHHHHHHHHHHHHHH
ITEANIAKNDLDVIAATAGPGLIGAVMVGLCFAEGMAFALGKPFVPVNHVEAHIFSPFIS
HHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHC
DEPGHKSPDGDFVSLTVSGGHTLLSVVRQNLDYEVIGRTIDDAAGEAFDKTGKMLGLGYP
CCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHCCCEEECCCC
AGPVIDRLARDGDPKFHRFPRALTSSSQTSKSYRGNFDFSFSGLKTSVRTWLEGHDAEFA
CHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHCCCCCEEHHHHHHHHHHHHCCCCHHHH
RQHQTDLAASIQDAIVSVLVEKTIAAALLHKVGAVSVAGGVSANSGLRSAMQAACNKHGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHCCCCC
DLFIPKATYSTDNAAMIATMAQLMMARGRYRENSYGVAPFARFKAAGKGTR
EEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA