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The map label for this gene is mpg1 [H]

Identifier: 193213569

GI number: 193213569

Start: 2129307

End: 2130239

Strand: Direct

Name: mpg1 [H]

Synonym: Cpar_1930

Alternate gene names: 193213569

Gene position: 2129307-2130239 (Clockwise)

Preceding gene: 193213568

Following gene: 193213570

Centisome position: 93.01

GC content: 57.77

Gene sequence:

>933_bases
ATGAACGCCTTCGTCCTGGCCGCCGGATTCGGCACCCGCCTGCAGCCGCTGACCGATACCCTACCCAAGCCGCTCATTCC
GGTGCTGAACGTGCCAAGCCTCTGCTACTCTCTGTTCCTGCTGAAAAGAGCTGGTATCAGCAAAGCGATCATCAACATTC
ACCACCATCAGGAGAGCATCCGCCGCTTTTTCGACGAGCACGACTTCGGCGGTCTCGAAATTGTACTGTCCGAAGAGCCG
ACCATCCTCGGCACCGGTGGCGGCCTGAAGAAGTGCGAAGCGCTGCTCGGCGATGAGGAGTTCCTGCTCATCAACAGCGA
TATTATTAGCGACATCGACCTGCGCTCGCTCATCGACACGCACCGGCGATCGGACACAGGTGGCACGCTGGCCCTGTATG
AAACTCCGCTGGCAGCAGAGATCGGCCACATCGGCGTCAAAGATGGCCGTGTGCTCGATTTCCGCAACCGGCGTGGCACT
GGGCTTGACTCTTCCTTCATCTACACCGGTACGGCGATATTGAGCCCTGCCATTTTCCAGCATCTGGAGAGCGGCTACTC
AGGCATCGTCGAAACCGGATTTAATGGGCTCGTGGAAAACGAAGGTCTCGCCTTTTACGAGCACAAGGGGTTGTGGCAGG
ACATCGGTACGTTGCCGAACTTTTACCGCGCGAACCTTGACGATAATTTGCGTATCCTTCAACTTGCGGCAGAAATGAAA
CAGCAGATCGGCTTTTTCCCCCATCGGATCTCGCCTGAAGCCTCGATCAGCCCGGATGCAACGGTCATCGATTCGGTGAT
CGGCGCGAACTGCTCCATCGCGAAGGGCGCGGTCGTGGAGCACTCGGTACTGCTGCCCGGCACGATAATCGGCCCGGATG
AAGCTGTCAGAAATTCAATTGCCGCACCACCGAACGTGCGCATTCCGCTCTGA

Upstream 100 bases:

>100_bases
ACATCGCACCGACGCTGGGCTACCTGCGCGACTACATCGAAGCACGCCCGGAGCTTGCAACCGCAGGCGAGCTGCTTGAA
CCACTCATTTCCCGCTGACC

Downstream 100 bases:

>100_bases
ACCTCTCATTTCACAAACGGCATGGTCATCAACGGTCTCGACATCCTGCTCGGCAATCCCGATCTGCTGGCTGGCAGAAG
CATCGGCCTGATCGCCAACC

Product: Nucleotidyl transferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MNAFVLAAGFGTRLQPLTDTLPKPLIPVLNVPSLCYSLFLLKRAGISKAIINIHHHQESIRRFFDEHDFGGLEIVLSEEP
TILGTGGGLKKCEALLGDEEFLLINSDIISDIDLRSLIDTHRRSDTGGTLALYETPLAAEIGHIGVKDGRVLDFRNRRGT
GLDSSFIYTGTAILSPAIFQHLESGYSGIVETGFNGLVENEGLAFYEHKGLWQDIGTLPNFYRANLDDNLRILQLAAEMK
QQIGFFPHRISPEASISPDATVIDSVIGANCSIAKGAVVEHSVLLPGTIIGPDEAVRNSIAAPPNVRIPL

Sequences:

>Translated_310_residues
MNAFVLAAGFGTRLQPLTDTLPKPLIPVLNVPSLCYSLFLLKRAGISKAIINIHHHQESIRRFFDEHDFGGLEIVLSEEP
TILGTGGGLKKCEALLGDEEFLLINSDIISDIDLRSLIDTHRRSDTGGTLALYETPLAAEIGHIGVKDGRVLDFRNRRGT
GLDSSFIYTGTAILSPAIFQHLESGYSGIVETGFNGLVENEGLAFYEHKGLWQDIGTLPNFYRANLDDNLRILQLAAEMK
QQIGFFPHRISPEASISPDATVIDSVIGANCSIAKGAVVEHSVLLPGTIIGPDEAVRNSIAAPPNVRIPL
>Mature_310_residues
MNAFVLAAGFGTRLQPLTDTLPKPLIPVLNVPSLCYSLFLLKRAGISKAIINIHHHQESIRRFFDEHDFGGLEIVLSEEP
TILGTGGGLKKCEALLGDEEFLLINSDIISDIDLRSLIDTHRRSDTGGTLALYETPLAAEIGHIGVKDGRVLDFRNRRGT
GLDSSFIYTGTAILSPAIFQHLESGYSGIVETGFNGLVENEGLAFYEHKGLWQDIGTLPNFYRANLDDNLRILQLAAEMK
QQIGFFPHRISPEASISPDATVIDSVIGANCSIAKGAVVEHSVLLPGTIIGPDEAVRNSIAAPPNVRIPL

Specific function: May Play A Role In Stationary Phase Survival. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=304, Percent_Identity=26.6447368421053, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI11761619, Length=310, Percent_Identity=28.0645161290323, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI133931050, Length=318, Percent_Identity=27.0440251572327, Blast_Score=100, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6320148, Length=315, Percent_Identity=27.3015873015873, Blast_Score=111, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21355443, Length=307, Percent_Identity=26.3843648208469, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24644084, Length=307, Percent_Identity=26.3843648208469, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 33631; Mature: 33631

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAFVLAAGFGTRLQPLTDTLPKPLIPVLNVPSLCYSLFLLKRAGISKAIINIHHHQESI
CCEEEEECCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
RRFFDEHDFGGLEIVLSEEPTILGTGGGLKKCEALLGDEEFLLINSDIISDIDLRSLIDT
HHHHHCCCCCCEEEEEECCCEEEECCCCHHHHHHHHCCCEEEEEECCHHCCHHHHHHHHH
HRRSDTGGTLALYETPLAAEIGHIGVKDGRVLDFRNRRGTGLDSSFIYTGTAILSPAIFQ
HCCCCCCCEEEEECCCHHHHHCCCCCCCCEEEECCCCCCCCCCCCEEEECHHHHHHHHHH
HLESGYSGIVETGFNGLVENEGLAFYEHKGLWQDIGTLPNFYRANLDDNLRILQLAAEMK
HHHHCCCHHHHHCCCCCCCCCCEEEEECCCHHHHHHCCCCCEECCCCCCHHHHHHHHHHH
QQIGFFPHRISPEASISPDATVIDSVIGANCSIAKGAVVEHSVLLPGTIIGPDEAVRNSI
HHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEECEEECCCEEECCHHHHHHCC
AAPPNVRIPL
CCCCCCCCCC
>Mature Secondary Structure
MNAFVLAAGFGTRLQPLTDTLPKPLIPVLNVPSLCYSLFLLKRAGISKAIINIHHHQESI
CCEEEEECCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
RRFFDEHDFGGLEIVLSEEPTILGTGGGLKKCEALLGDEEFLLINSDIISDIDLRSLIDT
HHHHHCCCCCCEEEEEECCCEEEECCCCHHHHHHHHCCCEEEEEECCHHCCHHHHHHHHH
HRRSDTGGTLALYETPLAAEIGHIGVKDGRVLDFRNRRGTGLDSSFIYTGTAILSPAIFQ
HCCCCCCCEEEEECCCHHHHHCCCCCCCCEEEECCCCCCCCCCCCEEEECHHHHHHHHHH
HLESGYSGIVETGFNGLVENEGLAFYEHKGLWQDIGTLPNFYRANLDDNLRILQLAAEMK
HHHHCCCHHHHHCCCCCCCCCCEEEEECCCHHHHHHCCCCCEECCCCCCHHHHHHHHHHH
QQIGFFPHRISPEASISPDATVIDSVIGANCSIAKGAVVEHSVLLPGTIIGPDEAVRNSI
HHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEECEEECCCEEECCHHHHHHCC
AAPPNVRIPL
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]