Click here to switch to the map view.

The map label for this gene is glmU [H]

Identifier: 193213422

GI number: 193213422

Start: 1955929

End: 1956672

Strand: Direct

Name: glmU [H]

Synonym: Cpar_1783

Alternate gene names: 193213422

Gene position: 1955929-1956672 (Clockwise)

Preceding gene: 193213421

Following gene: 193213441

Centisome position: 85.44

GC content: 56.05

Gene sequence:

>744_bases
ATGAGTTTGGCAATCGTCATCATGGCAGCCGGTAAAGGCACAAGAATGAAGTCCGACCTGCCCAAAGTGCTGCACCAGGC
CAACGGTAGACCGGTCGTCGAGTATGTCATCGAAAAATCGCAAGCGCTCGAACCTGAAATGATCGTACTGATCACCGGTC
ACCAGTCGGAGAAGGTACGCCAAGCCACGAGCAAATTTGACGTTCGTTACGCCTTGCAGGAGCCGCAGCACGGCACCGGC
CATGCGGTCATGCAGGCTGAACCATTGCTGAAGGAGTTTGACGGAGAGATCATCATTCTGTCGGGTGACGCCCCGCTCTT
CACCACCGCCACGCTGAAAGAGCTAGTGGCGTTCCATCGCGCGAACAGGGCCGTCGCCACTGTGCTGACTGCCAAGATTG
ACGACCCGACCGGCTACGGACGAGTCATCCGGAGCGGCGACGGCGAGGAGGTGCTACGAATCGTCGAACAGAAAGATGCC
AGCGACGAAGAGAAAGCGGTCAACGAAATCAATTCTGGCGTCTATGTCTTCAACGCTACCGAGCTGTTTGATGCGTTGCA
CAGCATCACCAATGAAAACGCTCAGCAGGAGTACTACCTGACCGACGTGTTCGGTATCTGCTTTGGCAAAGGCCTGAAAG
TGTGCGCTTTCAAAGTTGCTGACCCCAACGAAATCCGCGGCATCAACACCCCCGAACAGCTCAGGGAAGCCGAAACGCTC
CTGCTGAGCGGCAACTACGTGTAA

Upstream 100 bases:

>100_bases
CGTTGACCGGATGAACAACCCGAAACGCCGTCACCGTGTCGGCAAAGACAATGAATATCTCGGCTGAGAATCATTTCAAA
TCCGGACAAATACCCCTTTT

Downstream 100 bases:

>100_bases
AAGACGAAGAGGCCGGAAGTTGCTGACAAAACTTCCGGCCCCCTGATCACTGCATCCGCTCCAACCGTTTCTCAATAAAG
AAACATCGGCTTGCCCATAA

Product: Nucleotidyl transferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MSLAIVIMAAGKGTRMKSDLPKVLHQANGRPVVEYVIEKSQALEPEMIVLITGHQSEKVRQATSKFDVRYALQEPQHGTG
HAVMQAEPLLKEFDGEIIILSGDAPLFTTATLKELVAFHRANRAVATVLTAKIDDPTGYGRVIRSGDGEEVLRIVEQKDA
SDEEKAVNEINSGVYVFNATELFDALHSITNENAQQEYYLTDVFGICFGKGLKVCAFKVADPNEIRGINTPEQLREAETL
LLSGNYV

Sequences:

>Translated_247_residues
MSLAIVIMAAGKGTRMKSDLPKVLHQANGRPVVEYVIEKSQALEPEMIVLITGHQSEKVRQATSKFDVRYALQEPQHGTG
HAVMQAEPLLKEFDGEIIILSGDAPLFTTATLKELVAFHRANRAVATVLTAKIDDPTGYGRVIRSGDGEEVLRIVEQKDA
SDEEKAVNEINSGVYVFNATELFDALHSITNENAQQEYYLTDVFGICFGKGLKVCAFKVADPNEIRGINTPEQLREAETL
LLSGNYV
>Mature_246_residues
SLAIVIMAAGKGTRMKSDLPKVLHQANGRPVVEYVIEKSQALEPEMIVLITGHQSEKVRQATSKFDVRYALQEPQHGTGH
AVMQAEPLLKEFDGEIIILSGDAPLFTTATLKELVAFHRANRAVATVLTAKIDDPTGYGRVIRSGDGEEVLRIVEQKDAS
DEEKAVNEINSGVYVFNATELFDALHSITNENAQQEYYLTDVFGICFGKGLKVCAFKVADPNEIRGINTPEQLREAETLL
LSGNYV

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=252, Percent_Identity=39.2857142857143, Blast_Score=182, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6320148, Length=192, Percent_Identity=27.0833333333333, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR018357
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 27146; Mature: 27015

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLAIVIMAAGKGTRMKSDLPKVLHQANGRPVVEYVIEKSQALEPEMIVLITGHQSEKVR
CCEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHH
QATSKFDVRYALQEPQHGTGHAVMQAEPLLKEFDGEIIILSGDAPLFTTATLKELVAFHR
HHHHHHHEEEEECCCCCCCCCEEEECCHHHHHCCCCEEEEECCCCEEHHHHHHHHHHHHH
ANRAVATVLTAKIDDPTGYGRVIRSGDGEEVLRIVEQKDASDEEKAVNEINSGVYVFNAT
CCHHEEEEEEEECCCCCCCCCEEECCCHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEHH
ELFDALHSITNENAQQEYYLTDVFGICFGKGLKVCAFKVADPNEIRGINTPEQLREAETL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCHHCCCCCCHHHHHHHHEE
LLSGNYV
EECCCCC
>Mature Secondary Structure 
SLAIVIMAAGKGTRMKSDLPKVLHQANGRPVVEYVIEKSQALEPEMIVLITGHQSEKVR
CEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHH
QATSKFDVRYALQEPQHGTGHAVMQAEPLLKEFDGEIIILSGDAPLFTTATLKELVAFHR
HHHHHHHEEEEECCCCCCCCCEEEECCHHHHHCCCCEEEEECCCCEEHHHHHHHHHHHHH
ANRAVATVLTAKIDDPTGYGRVIRSGDGEEVLRIVEQKDASDEEKAVNEINSGVYVFNAT
CCHHEEEEEEEECCCCCCCCCEEECCCHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEHH
ELFDALHSITNENAQQEYYLTDVFGICFGKGLKVCAFKVADPNEIRGINTPEQLREAETL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCHHCCCCCCHHHHHHHHEE
LLSGNYV
EECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA