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The map label for this gene is luxO [H]

Identifier: 193213229

GI number: 193213229

Start: 1733444

End: 1734562

Strand: Direct

Name: luxO [H]

Synonym: Cpar_1584

Alternate gene names: 193213229

Gene position: 1733444-1734562 (Clockwise)

Preceding gene: 193213228

Following gene: 193213231

Centisome position: 75.72

GC content: 57.02

Gene sequence:

>1119_bases
ATGAAGAAGGAATTCGATATCATCGGCCGTTCTCAGGCAATTCTTCAGCTTAAAGAGCTCGCTTTGCAGGTAGCCGCGAC
CGACGTTACGGTGCTCATCACCGGCGAAACCGGTTCGGGCAAGGAGGTGCTCTCGCGCTTTATCCACGAGCACAGCCGGC
GGGTTGGCAAGAGCTTTATTCCGGTCAACTGCGGCGCGATTCCATCGGGCATTCTCGAATCGGAGCTGTTCGGCCACGAG
AAGGGCGCGTTCACCGGGGCGGTGCAGGCACGAAAGGGCTATTTCGAAAGCGCCGACAAGGGCACGATCTTTCTGGATGA
AATCGGTGAAATGCCGCTTGAAACACAGGTAAAACTCCTGCGCATCATCGAAACCGGTCAGTTCCAGCGGGTTGGCTCCT
CTGAAACGATCTCCATCGATACCCGTATCATCGCGGCCACGAACCGGAACCTTACGCAGGAGGTCACCGAAAAGAATTTC
AGGGAGGATCTTTACTACCGCCTGCGAAGCGTCGAACTGCATCTTCCGCCGCTCAGGGAGAGGGGCAGCGATATTCTGAT
GCTGGCCGAGCATTTCGTGCACGAGTTCGAACGCAAGCACGGCATTGCGTTTCAGGGGTTCAGCCACGATTCGGGCGAAC
TGCTGTTGCGTTACCCGTGGCCGGGTAATGTCAGGGAGCTGCGCAACCTGATCGAATCGCTGCTTATTCTTGAAAGGGGC
AAAGAGATCACGCCTGACCTCCTCGAAAAGCACCTGATTCAGCGAAGCCGCCACAAAAGCCTGGTCCACGACCCTGGCAA
ATCGGACAAAAACGAGATGCACCTCATTTACAGCAGCCTCATTCAGCTGCGGCAGGAGATCGGTGAAATCCGGCAGATGC
TGCAACAGACGCTCATGTCGCGCCCGGCGACGAGCAGTCCCCTGCTCCTGCCCCCATCATCCGCCCAAGCTCCTACGCCA
GCCGCGCCAGCCGCCGAGGTGATGCCGCTTGAAGAAATTGAAAAGCGCGCCATTGCCGAAGCTCTTGCAACCTTCGAAGG
CAACAAACGCAGAACAGCCCAGGCCCTCGGAATCAACGAGCGGACGCTCTATCGCAAGATCAAGGAATATGGATTGTAG

Upstream 100 bases:

>100_bases
CAGGAGGCTGCGGCGTTCGGGCGCACGATGCCAATTGAGTCGATCGTGGTTCCCGCCCAGCCATGATCCGGCACACCATT
TCGCATCAGACCGCAGGTTC

Downstream 100 bases:

>100_bases
GGAAGATATGGAGGTCATAGGCAAGAAAGTGCTGCACACCGACCAATCGACCAATCATTTCAAACCATCCCTCAGACCAC
CCTTTTTCGAACTACCGCCA

Product: Fis family sigma-54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MKKEFDIIGRSQAILQLKELALQVAATDVTVLITGETGSGKEVLSRFIHEHSRRVGKSFIPVNCGAIPSGILESELFGHE
KGAFTGAVQARKGYFESADKGTIFLDEIGEMPLETQVKLLRIIETGQFQRVGSSETISIDTRIIAATNRNLTQEVTEKNF
REDLYYRLRSVELHLPPLRERGSDILMLAEHFVHEFERKHGIAFQGFSHDSGELLLRYPWPGNVRELRNLIESLLILERG
KEITPDLLEKHLIQRSRHKSLVHDPGKSDKNEMHLIYSSLIQLRQEIGEIRQMLQQTLMSRPATSSPLLLPPSSAQAPTP
AAPAAEVMPLEEIEKRAIAEALATFEGNKRRTAQALGINERTLYRKIKEYGL

Sequences:

>Translated_372_residues
MKKEFDIIGRSQAILQLKELALQVAATDVTVLITGETGSGKEVLSRFIHEHSRRVGKSFIPVNCGAIPSGILESELFGHE
KGAFTGAVQARKGYFESADKGTIFLDEIGEMPLETQVKLLRIIETGQFQRVGSSETISIDTRIIAATNRNLTQEVTEKNF
REDLYYRLRSVELHLPPLRERGSDILMLAEHFVHEFERKHGIAFQGFSHDSGELLLRYPWPGNVRELRNLIESLLILERG
KEITPDLLEKHLIQRSRHKSLVHDPGKSDKNEMHLIYSSLIQLRQEIGEIRQMLQQTLMSRPATSSPLLLPPSSAQAPTP
AAPAAEVMPLEEIEKRAIAEALATFEGNKRRTAQALGINERTLYRKIKEYGL
>Mature_372_residues
MKKEFDIIGRSQAILQLKELALQVAATDVTVLITGETGSGKEVLSRFIHEHSRRVGKSFIPVNCGAIPSGILESELFGHE
KGAFTGAVQARKGYFESADKGTIFLDEIGEMPLETQVKLLRIIETGQFQRVGSSETISIDTRIIAATNRNLTQEVTEKNF
REDLYYRLRSVELHLPPLRERGSDILMLAEHFVHEFERKHGIAFQGFSHDSGELLLRYPWPGNVRELRNLIESLLILERG
KEITPDLLEKHLIQRSRHKSLVHDPGKSDKNEMHLIYSSLIQLRQEIGEIRQMLQQTLMSRPATSSPLLLPPSSAQAPTP
AAPAAEVMPLEEIEKRAIAEALATFEGNKRRTAQALGINERTLYRKIKEYGL

Specific function: Acts negatively to control the expression of luminescence. At low cell density, luxO is phosphorylated, and together with sigma-54, causes repression of the luxCDABEGH operon. This repression could be indirect, luxO could activate a negative regulator of

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI87082117, Length=239, Percent_Identity=50.6276150627615, Blast_Score=250, Evalue=1e-67,
Organism=Escherichia coli, GI1789087, Length=252, Percent_Identity=48.4126984126984, Blast_Score=244, Evalue=9e-66,
Organism=Escherichia coli, GI1789233, Length=368, Percent_Identity=38.8586956521739, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1790299, Length=368, Percent_Identity=38.3152173913043, Blast_Score=241, Evalue=4e-65,
Organism=Escherichia coli, GI1788550, Length=234, Percent_Identity=49.5726495726496, Blast_Score=241, Evalue=6e-65,
Organism=Escherichia coli, GI1790437, Length=242, Percent_Identity=48.7603305785124, Blast_Score=235, Evalue=3e-63,
Organism=Escherichia coli, GI1788905, Length=246, Percent_Identity=47.5609756097561, Blast_Score=235, Evalue=4e-63,
Organism=Escherichia coli, GI87082152, Length=238, Percent_Identity=47.4789915966387, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1786524, Length=276, Percent_Identity=42.7536231884058, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI87081872, Length=228, Percent_Identity=45.1754385964912, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1787583, Length=239, Percent_Identity=42.2594142259414, Blast_Score=201, Evalue=9e-53,
Organism=Escherichia coli, GI1789828, Length=260, Percent_Identity=35.3846153846154, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI87081858, Length=231, Percent_Identity=32.4675324675325, Blast_Score=117, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 41917; Mature: 41917

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEFDIIGRSQAILQLKELALQVAATDVTVLITGETGSGKEVLSRFIHEHSRRVGKSFI
CCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCC
PVNCGAIPSGILESELFGHEKGAFTGAVQARKGYFESADKGTIFLDEIGEMPLETQVKLL
CCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEEHHHHCCCCHHHHHHHH
RIIETGQFQRVGSSETISIDTRIIAATNRNLTQEVTEKNFREDLYYRLRSVELHLPPLRE
HHHHCCCCEECCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEECCCHHH
RGSDILMLAEHFVHEFERKHGIAFQGFSHDSGELLLRYPWPGNVRELRNLIESLLILERG
CCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCC
KEITPDLLEKHLIQRSRHKSLVHDPGKSDKNEMHLIYSSLIQLRQEIGEIRQMLQQTLMS
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RPATSSPLLLPPSSAQAPTPAAPAAEVMPLEEIEKRAIAEALATFEGNKRRTAQALGINE
CCCCCCCEEECCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCH
RTLYRKIKEYGL
HHHHHHHHHHCC
>Mature Secondary Structure
MKKEFDIIGRSQAILQLKELALQVAATDVTVLITGETGSGKEVLSRFIHEHSRRVGKSFI
CCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCC
PVNCGAIPSGILESELFGHEKGAFTGAVQARKGYFESADKGTIFLDEIGEMPLETQVKLL
CCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEEHHHHCCCCHHHHHHHH
RIIETGQFQRVGSSETISIDTRIIAATNRNLTQEVTEKNFREDLYYRLRSVELHLPPLRE
HHHHCCCCEECCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEECCCHHH
RGSDILMLAEHFVHEFERKHGIAFQGFSHDSGELLLRYPWPGNVRELRNLIESLLILERG
CCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCC
KEITPDLLEKHLIQRSRHKSLVHDPGKSDKNEMHLIYSSLIQLRQEIGEIRQMLQQTLMS
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RPATSSPLLLPPSSAQAPTPAAPAAEVMPLEEIEKRAIAEALATFEGNKRRTAQALGINE
CCCCCCCEEECCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCH
RTLYRKIKEYGL
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8065259 [H]