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The map label for this gene is sucC

Identifier: 193213142

GI number: 193213142

Start: 1639310

End: 1640488

Strand: Direct

Name: sucC

Synonym: Cpar_1497

Alternate gene names: 193213142

Gene position: 1639310-1640488 (Clockwise)

Preceding gene: 193213140

Following gene: 193213146

Centisome position: 71.61

GC content: 57.34

Gene sequence:

>1179_bases
ATGAATATTCATGAGTATCAGGGCAAAGGCATCCTGAAACAGTTCGGTGTGGCCGTTCCCAAGGGCATAGTAGCATTTTC
GGCTGAAGAAGCAAAACAGGCTGCGGCCGAGCTTTTCGAAGAGCAGTCAAGCCCCGTAGTGGTCGTCAAAGCGCAGATCC
ACGCAGGTGGGCGCGGCAAGGCCGGCGGCGTCAAGCTGGCCAAATCCCCCGAAGAGGTGTATGAAATTGCCCAGAAAATG
CTCGGCACCACACTGGTAACCCACCAGACCGGCCCCGAAGGCAAGGAGGTCAGGAGACTGCTGATTGAAGAGGGCATGAA
CATCGACAAAGAGTTCTACCTCGGCATCACCCTCGATCGCGCTACGTCGTGCAACGTGCTGATGGTCTCGACCGAAGGTG
GCATGGAGATCGAAAAGGTGGCCGAAGAGACCCCCGAAAAGCTCCTCAAAATTCAGGTCAATCCGAAGTACGGCCTGCAG
GGCTTCCAGGCTCGTGAAGCGGCGCTCTTCCTCGGCATGCAGGGTGAGCAGTTCCGCAATGGCGTCAAGTTCATCGATGC
GCTGTACAAAGCATACACTACCATCGACGCCTCGCTGGCAGAAATCAACCCGCTCGTGGTTACCAAAGAGGGACGCGTGC
TGGCTCTCGACGCCAAGATCAACTTCGATGACAATGCCATGTACCGTCATCCGGATTTCCACGAACTGCGTGACATCACC
GAAGAAGATCCGCTTGAGTACGAAGCATCGAAGTCGAACCTCAACTACGTGCGCCTCGACGGCAACGTCGGCTGCATGGT
CAACGGTGCCGGCCTTGCCATGGGCACTATGGACCTCATCCAGCTTGCCGGCGGCAAACCGGCCAACTTCCTCGACGTAG
GCGGTGGCGCCAGCCCCAAAACGGTTGAAGAGGGCTTCAAGATTATCCTCGGCGACAAAAACGTCAAGGCCATCCTTGTC
AATGTCTTCGGTGGCATCGTGCGCTGCGACCGCGTTGCCGGAGGCGTCATCGAAGCTGCCAAGAATATTGGCCTGACAGT
ACCGGTCATCGTGCGCCTCGAAGGCACCAATGCCAAAGAGGCACAGAAAATGCTCGATGAATCTGGCCTCAGCCTCATCG
CCGCCAACGGCCTGAGGGATGCCGCTGAAAAGGTGCAGAAAGCACTCGCCTCGGCCTGA

Upstream 100 bases:

>100_bases
TAAAAGCAGAAATTTTGTTATCATAAAGTTTAAACTTTTTCCGCATTGAAGCCCGGTTTTCAACCGGCGCGTATTCTTCG
ATAACCATAGAACCTCTGCG

Downstream 100 bases:

>100_bases
GCCCTGTCCATACAAAGCATTAAAGCAGAAAAGCCCGCTTCCACTACCGATGTGAAAGCGGGCTTTTGCTTTGCCTCGAA
ACCTGAAAATTCATCCCCCA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MNIHEYQGKGILKQFGVAVPKGIVAFSAEEAKQAAAELFEEQSSPVVVVKAQIHAGGRGKAGGVKLAKSPEEVYEIAQKM
LGTTLVTHQTGPEGKEVRRLLIEEGMNIDKEFYLGITLDRATSCNVLMVSTEGGMEIEKVAEETPEKLLKIQVNPKYGLQ
GFQAREAALFLGMQGEQFRNGVKFIDALYKAYTTIDASLAEINPLVVTKEGRVLALDAKINFDDNAMYRHPDFHELRDIT
EEDPLEYEASKSNLNYVRLDGNVGCMVNGAGLAMGTMDLIQLAGGKPANFLDVGGGASPKTVEEGFKIILGDKNVKAILV
NVFGGIVRCDRVAGGVIEAAKNIGLTVPVIVRLEGTNAKEAQKMLDESGLSLIAANGLRDAAEKVQKALASA

Sequences:

>Translated_392_residues
MNIHEYQGKGILKQFGVAVPKGIVAFSAEEAKQAAAELFEEQSSPVVVVKAQIHAGGRGKAGGVKLAKSPEEVYEIAQKM
LGTTLVTHQTGPEGKEVRRLLIEEGMNIDKEFYLGITLDRATSCNVLMVSTEGGMEIEKVAEETPEKLLKIQVNPKYGLQ
GFQAREAALFLGMQGEQFRNGVKFIDALYKAYTTIDASLAEINPLVVTKEGRVLALDAKINFDDNAMYRHPDFHELRDIT
EEDPLEYEASKSNLNYVRLDGNVGCMVNGAGLAMGTMDLIQLAGGKPANFLDVGGGASPKTVEEGFKIILGDKNVKAILV
NVFGGIVRCDRVAGGVIEAAKNIGLTVPVIVRLEGTNAKEAQKMLDESGLSLIAANGLRDAAEKVQKALASA
>Mature_392_residues
MNIHEYQGKGILKQFGVAVPKGIVAFSAEEAKQAAAELFEEQSSPVVVVKAQIHAGGRGKAGGVKLAKSPEEVYEIAQKM
LGTTLVTHQTGPEGKEVRRLLIEEGMNIDKEFYLGITLDRATSCNVLMVSTEGGMEIEKVAEETPEKLLKIQVNPKYGLQ
GFQAREAALFLGMQGEQFRNGVKFIDALYKAYTTIDASLAEINPLVVTKEGRVLALDAKINFDDNAMYRHPDFHELRDIT
EEDPLEYEASKSNLNYVRLDGNVGCMVNGAGLAMGTMDLIQLAGGKPANFLDVGGGASPKTVEEGFKIILGDKNVKAILV
NVFGGIVRCDRVAGGVIEAAKNIGLTVPVIVRLEGTNAKEAQKMLDESGLSLIAANGLRDAAEKVQKALASA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=394, Percent_Identity=44.6700507614213, Blast_Score=335, Evalue=3e-92,
Organism=Homo sapiens, GI157779135, Length=387, Percent_Identity=45.2196382428941, Blast_Score=325, Evalue=4e-89,
Organism=Homo sapiens, GI294862256, Length=363, Percent_Identity=44.9035812672176, Blast_Score=303, Evalue=2e-82,
Organism=Escherichia coli, GI1786948, Length=389, Percent_Identity=50.8997429305913, Blast_Score=379, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17539378, Length=398, Percent_Identity=42.964824120603, Blast_Score=324, Evalue=6e-89,
Organism=Caenorhabditis elegans, GI17567829, Length=393, Percent_Identity=41.7302798982188, Blast_Score=310, Evalue=1e-84,
Organism=Saccharomyces cerevisiae, GI6321683, Length=395, Percent_Identity=42.5316455696203, Blast_Score=332, Evalue=5e-92,
Organism=Drosophila melanogaster, GI21356231, Length=398, Percent_Identity=45.7286432160804, Blast_Score=334, Evalue=5e-92,
Organism=Drosophila melanogaster, GI161078106, Length=390, Percent_Identity=42.8205128205128, Blast_Score=313, Evalue=2e-85,
Organism=Drosophila melanogaster, GI24645208, Length=390, Percent_Identity=42.8205128205128, Blast_Score=313, Evalue=2e-85,
Organism=Drosophila melanogaster, GI281361397, Length=391, Percent_Identity=42.9667519181586, Blast_Score=311, Evalue=4e-85,
Organism=Drosophila melanogaster, GI281361395, Length=391, Percent_Identity=42.9667519181586, Blast_Score=311, Evalue=4e-85,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_CHLP8 (B3QPP2)

Other databases:

- EMBL:   CP001099
- RefSeq:   YP_001999095.1
- GeneID:   6420439
- GenomeReviews:   CP001099_GR
- KEGG:   cpc:Cpar_1497
- HOGENOM:   HBG315432
- OMA:   NPLIVMK
- ProtClustDB:   PRK00696
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 42092; Mature: 42092

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQGKGILKQFGVAVPKGIVAFSAEEAKQAAAELFEEQSSPVVVVKAQIHAGGRGK
CCCCCCCCCCHHHHHCCCCCCCCEEECHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCC
AGGVKLAKSPEEVYEIAQKMLGTTLVTHQTGPEGKEVRRLLIEEGMNIDKEFYLGITLDR
CCCEEECCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEEEEEC
ATSCNVLMVSTEGGMEIEKVAEETPEKLLKIQVNPKYGLQGFQAREAALFLGMQGEQFRN
CCCCCEEEEECCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCHHCCEEEEECCCCHHHHH
GVKFIDALYKAYTTIDASLAEINPLVVTKEGRVLALDAKINFDDNAMYRHPDFHELRDIT
HHHHHHHHHHHHHHHCCHHHHCCCEEEECCCCEEEEEEEECCCCCCEECCCCHHHHHCCC
EEDPLEYEASKSNLNYVRLDGNVGCMVNGAGLAMGTMDLIQLAGGKPANFLDVGGGASPK
CCCCCCEECCCCCCCEEEECCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEECCCCCCCH
TVEEGFKIILGDKNVKAILVNVFGGIVRCDRVAGGVIEAAKNIGLTVPVIVRLEGTNAKE
HHHCCCEEEECCCCHHEEHEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHH
AQKMLDESGLSLIAANGLRDAAEKVQKALASA
HHHHHHHCCCEEEEECCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQGKGILKQFGVAVPKGIVAFSAEEAKQAAAELFEEQSSPVVVVKAQIHAGGRGK
CCCCCCCCCCHHHHHCCCCCCCCEEECHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCC
AGGVKLAKSPEEVYEIAQKMLGTTLVTHQTGPEGKEVRRLLIEEGMNIDKEFYLGITLDR
CCCEEECCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEEEEEC
ATSCNVLMVSTEGGMEIEKVAEETPEKLLKIQVNPKYGLQGFQAREAALFLGMQGEQFRN
CCCCCEEEEECCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCHHCCEEEEECCCCHHHHH
GVKFIDALYKAYTTIDASLAEINPLVVTKEGRVLALDAKINFDDNAMYRHPDFHELRDIT
HHHHHHHHHHHHHHHCCHHHHCCCEEEECCCCEEEEEEEECCCCCCEECCCCHHHHHCCC
EEDPLEYEASKSNLNYVRLDGNVGCMVNGAGLAMGTMDLIQLAGGKPANFLDVGGGASPK
CCCCCCEECCCCCCCEEEECCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEECCCCCCCH
TVEEGFKIILGDKNVKAILVNVFGGIVRCDRVAGGVIEAAKNIGLTVPVIVRLEGTNAKE
HHHCCCEEEECCCCHHEEHEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHH
AQKMLDESGLSLIAANGLRDAAEKVQKALASA
HHHHHHHCCCEEEEECCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA