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The map label for this gene is atoS [C]

Identifier: 193213014

GI number: 193213014

Start: 1479290

End: 1481374

Strand: Direct

Name: atoS [C]

Synonym: Cpar_1365

Alternate gene names: 193213014

Gene position: 1479290-1481374 (Clockwise)

Preceding gene: 193213007

Following gene: 193213017

Centisome position: 64.62

GC content: 46.19

Gene sequence:

>2085_bases
ATGCCCAAGGATAAGCTCAACTGTAATGCTGAAAAAAGCACCCAACAAGCAGAAACGAGTGACAGCTCTTCGACCGTGAC
TCCACAAAGCGAAACATTTTTTTTAAAGGCATTCGAAAACCATTCTGCCGTGATGCTGCTGATCGATGCTGAATCCGGGC
ACATCATCGATGCTAACCAAGCAGCTACAGAGTTTTACGGATGGCCCATCGAACAGCTCAAGTCAAAAAACATCAATGAA
ATCGATGCGCCTTCATGGACGCGAAACAAGTCATGGTTGCTGGAGTTGGCGACACAGGAACGCGGCCGTTTTGCATCTAT
GCACCGCTGCGCTAACGGCATGCTTCAGTATGTGGAGGTAAGTTTCGGCACAACGAAGCTACAAGCTAAAACCGTGCTCC
ACTTCATCATGCAGGAAAACGGCGAACGTCAATACTTTGAGGCACTGACAAAATTCCGGCACCAACTGCTTGAACTGGCT
GAACACGCTTCGACCGAAGAGCTGCTTAACTTTACGATCAATGAGGCAGAACGTCTGACAGGCAGCACACTTGGCTTTTT
CAATTTCATTTCGGAAGACCATAAGATTTTTCGGCACGCCTGTTCGACTCTTGCAAAAACAGATAACTGCGGGCATGCCA
AGCCCCCCATTGAAATCGATCCCGAATTATTGGCAGATGTGATCTCACAAAAAAAAGTTGTGATCAACAACGATCATGCT
TCGATCAAGCATTGTAACAGCAATATCGCCAGCCATCAAGAAGCAAAACGCGAGCTGATCGTGCCAATCATTCGCAACGA
CAAGCTCATGGCAACACTTGAGCTCGCCAACAAACCGACCGATTACGATGAAAAAGACAGCACACTGGTAAGCATGCTTA
CTGGAGTAGCCTGGGACATCATCGCAAGAAAACATGCCGAAGAGTCAGAACAAAAAATGCTGAAAGCCATTCAGCATACA
CAGAATATGGATTCGATCGGCCGGCTTGCCGGAGGCATTGCCCATGACATCAACAATGGGCTTGCCGTTATCCTAGGGCA
CACTGAAATAGTTCTTGAACAGGTATCTCCGAAGGGCACGATCACCGAAAACCTTCAGCATATTAAAAATTCAACAGTAA
AAGCGGCTAACCTGATACAGCAATTGCTGGCATTTGCACGCAAACAAACGATCCACCCCAAAATTCTGGAACTCGATGCG
ACGCTTCTCACCAAGCTACCCTACCTGAGGAAGCTAATCGGGGAGCAACTGAATCTGGAGTGGCACCCCGACAGTCATGA
CGCAAAGATTCTGATTGATCCCTTACAGCTCGATCAGATAATGATAAGCCTGTGCGAAAACGCACGCGACGCCATTACCG
ACACTGGTACCGTCAGGATAGAAACAGCCACCGTCAGGGTTAAACCCTCCGATTGCTATTCCGATCATCCTTGCCAGACA
CCTGGATTATTTGCCATGATTTCAGTAATCGACACAGGCTGCGGAATGGACGAAAAAGTAATGTCCCAAATTTTCGACCC
TTTTTTCACCACCAAAGACGTCGGAAAAGGCTCTGGATTGGGACTATCAACCGTTTATGGTATTGTAAAGCAGAACAAGG
GCTATCTTAACTGCCAAAGCAATCCAGGCAATGGAAGCCGCTTTACAATTTATCTGCCCGTTGTCGAAAACAAAATCGAG
CCAGACAAAAAGATAACCCCGAAAGATGTCGCTAGTCCTGATGATAAGCAAACGATACTCGTAGTCGATGATAATGGGAC
CATTCTTTACATTGTTAAAACAGTGCTTGAGAAAAACAACTACCGTGTTCTTTCTACAACTTCAGCACAAGAGGCAATCA
ACATCGTAACAAACTCAGAGACAAGAGTCGATCTGCTGCTAACTGATGTAGTCATGCCAGAGATGAGCGGACAAGAACTT
TCAAAAAAACTTATCTCCATATTACCTCACCTGAAAACGATTTTCATGTCGGGCTTCTCAAAGGATCTGACAAACCTTAA
TGAGCTTGCTGAAAACGAGCGTTTCATCAGCAAACCGTTTAAGATGCGAGAATTCACCGCCACGATAAAAGCGATGCTGA
GCTGA

Upstream 100 bases:

>100_bases
ACGTTTTTCAAAAAAAACCAATATCTATGCAATAATACTCTCAATCTTCATTTTTTCATGTTATTTTTGAACTTAAATGT
TTTGAAAAATAACACTCGCC

Downstream 100 bases:

>100_bases
GCCCCCCAACAACCACAATACGCAACAAAAAAAGGCCCGCTTTCGCAGGCCTTTTTTTGTTGCTATGAGCAATCGGGGGA
TCAGTACATACCGCCCATGC

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 694; Mature: 693

Protein sequence:

>694_residues
MPKDKLNCNAEKSTQQAETSDSSSTVTPQSETFFLKAFENHSAVMLLIDAESGHIIDANQAATEFYGWPIEQLKSKNINE
IDAPSWTRNKSWLLELATQERGRFASMHRCANGMLQYVEVSFGTTKLQAKTVLHFIMQENGERQYFEALTKFRHQLLELA
EHASTEELLNFTINEAERLTGSTLGFFNFISEDHKIFRHACSTLAKTDNCGHAKPPIEIDPELLADVISQKKVVINNDHA
SIKHCNSNIASHQEAKRELIVPIIRNDKLMATLELANKPTDYDEKDSTLVSMLTGVAWDIIARKHAEESEQKMLKAIQHT
QNMDSIGRLAGGIAHDINNGLAVILGHTEIVLEQVSPKGTITENLQHIKNSTVKAANLIQQLLAFARKQTIHPKILELDA
TLLTKLPYLRKLIGEQLNLEWHPDSHDAKILIDPLQLDQIMISLCENARDAITDTGTVRIETATVRVKPSDCYSDHPCQT
PGLFAMISVIDTGCGMDEKVMSQIFDPFFTTKDVGKGSGLGLSTVYGIVKQNKGYLNCQSNPGNGSRFTIYLPVVENKIE
PDKKITPKDVASPDDKQTILVVDDNGTILYIVKTVLEKNNYRVLSTTSAQEAINIVTNSETRVDLLLTDVVMPEMSGQEL
SKKLISILPHLKTIFMSGFSKDLTNLNELAENERFISKPFKMREFTATIKAMLS

Sequences:

>Translated_694_residues
MPKDKLNCNAEKSTQQAETSDSSSTVTPQSETFFLKAFENHSAVMLLIDAESGHIIDANQAATEFYGWPIEQLKSKNINE
IDAPSWTRNKSWLLELATQERGRFASMHRCANGMLQYVEVSFGTTKLQAKTVLHFIMQENGERQYFEALTKFRHQLLELA
EHASTEELLNFTINEAERLTGSTLGFFNFISEDHKIFRHACSTLAKTDNCGHAKPPIEIDPELLADVISQKKVVINNDHA
SIKHCNSNIASHQEAKRELIVPIIRNDKLMATLELANKPTDYDEKDSTLVSMLTGVAWDIIARKHAEESEQKMLKAIQHT
QNMDSIGRLAGGIAHDINNGLAVILGHTEIVLEQVSPKGTITENLQHIKNSTVKAANLIQQLLAFARKQTIHPKILELDA
TLLTKLPYLRKLIGEQLNLEWHPDSHDAKILIDPLQLDQIMISLCENARDAITDTGTVRIETATVRVKPSDCYSDHPCQT
PGLFAMISVIDTGCGMDEKVMSQIFDPFFTTKDVGKGSGLGLSTVYGIVKQNKGYLNCQSNPGNGSRFTIYLPVVENKIE
PDKKITPKDVASPDDKQTILVVDDNGTILYIVKTVLEKNNYRVLSTTSAQEAINIVTNSETRVDLLLTDVVMPEMSGQEL
SKKLISILPHLKTIFMSGFSKDLTNLNELAENERFISKPFKMREFTATIKAMLS
>Mature_693_residues
PKDKLNCNAEKSTQQAETSDSSSTVTPQSETFFLKAFENHSAVMLLIDAESGHIIDANQAATEFYGWPIEQLKSKNINEI
DAPSWTRNKSWLLELATQERGRFASMHRCANGMLQYVEVSFGTTKLQAKTVLHFIMQENGERQYFEALTKFRHQLLELAE
HASTEELLNFTINEAERLTGSTLGFFNFISEDHKIFRHACSTLAKTDNCGHAKPPIEIDPELLADVISQKKVVINNDHAS
IKHCNSNIASHQEAKRELIVPIIRNDKLMATLELANKPTDYDEKDSTLVSMLTGVAWDIIARKHAEESEQKMLKAIQHTQ
NMDSIGRLAGGIAHDINNGLAVILGHTEIVLEQVSPKGTITENLQHIKNSTVKAANLIQQLLAFARKQTIHPKILELDAT
LLTKLPYLRKLIGEQLNLEWHPDSHDAKILIDPLQLDQIMISLCENARDAITDTGTVRIETATVRVKPSDCYSDHPCQTP
GLFAMISVIDTGCGMDEKVMSQIFDPFFTTKDVGKGSGLGLSTVYGIVKQNKGYLNCQSNPGNGSRFTIYLPVVENKIEP
DKKITPKDVASPDDKQTILVVDDNGTILYIVKTVLEKNNYRVLSTTSAQEAINIVTNSETRVDLLLTDVVMPEMSGQELS
KKLISILPHLKTIFMSGFSKDLTNLNELAENERFISKPFKMREFTATIKAMLS

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=259, Percent_Identity=31.2741312741313, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1790436, Length=333, Percent_Identity=25.2252252252252, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788713, Length=217, Percent_Identity=30.4147465437788, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI145693157, Length=350, Percent_Identity=26.2857142857143, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI87081816, Length=239, Percent_Identity=26.3598326359833, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI48994928, Length=374, Percent_Identity=26.2032085561497, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790300, Length=247, Percent_Identity=27.1255060728745, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 77488; Mature: 77357

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKDKLNCNAEKSTQQAETSDSSSTVTPQSETFFLKAFENHSAVMLLIDAESGHIIDANQ
CCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCEEECCH
AATEFYGWPIEQLKSKNINEIDAPSWTRNKSWLLELATQERGRFASMHRCANGMLQYVEV
HHHHHCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEE
SFGTTKLQAKTVLHFIMQENGERQYFEALTKFRHQLLELAEHASTEELLNFTINEAERLT
ECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
GSTLGFFNFISEDHKIFRHACSTLAKTDNCGHAKPPIEIDPELLADVISQKKVVINNDHA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCC
SIKHCNSNIASHQEAKRELIVPIIRNDKLMATLELANKPTDYDEKDSTLVSMLTGVAWDI
HHHHHCCHHHHHHHHHHHEEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
IARKHAEESEQKMLKAIQHTQNMDSIGRLAGGIAHDINNGLAVILGHTEIVLEQVSPKGT
HHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHCCCCCC
ITENLQHIKNSTVKAANLIQQLLAFARKQTIHPKILELDATLLTKLPYLRKLIGEQLNLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEE
WHPDSHDAKILIDPLQLDQIMISLCENARDAITDTGTVRIETATVRVKPSDCYSDHPCQT
ECCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCC
PGLFAMISVIDTGCGMDEKVMSQIFDPFFTTKDVGKGSGLGLSTVYGIVKQNKGYLNCQS
CCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECC
NPGNGSRFTIYLPVVENKIEPDKKITPKDVASPDDKQTILVVDDNGTILYIVKTVLEKNN
CCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEHHHHCCCC
YRVLSTTSAQEAINIVTNSETRVDLLLTDVVMPEMSGQELSKKLISILPHLKTIFMSGFS
EEEEEECCHHHHEEEEECCCCEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KDLTNLNELAENERFISKPFKMREFTATIKAMLS
HHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PKDKLNCNAEKSTQQAETSDSSSTVTPQSETFFLKAFENHSAVMLLIDAESGHIIDANQ
CCCCCCCCCCHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCEEECCH
AATEFYGWPIEQLKSKNINEIDAPSWTRNKSWLLELATQERGRFASMHRCANGMLQYVEV
HHHHHCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEE
SFGTTKLQAKTVLHFIMQENGERQYFEALTKFRHQLLELAEHASTEELLNFTINEAERLT
ECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
GSTLGFFNFISEDHKIFRHACSTLAKTDNCGHAKPPIEIDPELLADVISQKKVVINNDHA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCC
SIKHCNSNIASHQEAKRELIVPIIRNDKLMATLELANKPTDYDEKDSTLVSMLTGVAWDI
HHHHHCCHHHHHHHHHHHEEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
IARKHAEESEQKMLKAIQHTQNMDSIGRLAGGIAHDINNGLAVILGHTEIVLEQVSPKGT
HHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHCCCCCC
ITENLQHIKNSTVKAANLIQQLLAFARKQTIHPKILELDATLLTKLPYLRKLIGEQLNLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEE
WHPDSHDAKILIDPLQLDQIMISLCENARDAITDTGTVRIETATVRVKPSDCYSDHPCQT
ECCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCC
PGLFAMISVIDTGCGMDEKVMSQIFDPFFTTKDVGKGSGLGLSTVYGIVKQNKGYLNCQS
CCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECC
NPGNGSRFTIYLPVVENKIEPDKKITPKDVASPDDKQTILVVDDNGTILYIVKTVLEKNN
CCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEHHHHCCCC
YRVLSTTSAQEAINIVTNSETRVDLLLTDVVMPEMSGQELSKKLISILPHLKTIFMSGFS
EEEEEECCHHHHEEEEECCCCEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KDLTNLNELAENERFISKPFKMREFTATIKAMLS
HHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA