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The map label for this gene is lip3 [H]

Identifier: 193212980

GI number: 193212980

Start: 1443169

End: 1444020

Strand: Direct

Name: lip3 [H]

Synonym: Cpar_1330

Alternate gene names: 193212980

Gene position: 1443169-1444020 (Clockwise)

Preceding gene: 193212979

Following gene: 193212981

Centisome position: 63.04

GC content: 56.22

Gene sequence:

>852_bases
ATGGCGGCTCAAGACAGGTACATCACGCTTAGCGGTCACCGTCACCGGTATCTCGATACAGGGGGCAATGCTCCCGTAAT
GCTGCTTCTGCACGGGATTTCAGCATCGTTCGATTTTTACGATCCGGTCATACCGCAGCTTGCCGGCTCATTCAGGGTTC
TCGGTCTCGACCTGCTTGGATTCGGCGGCTCCGACAAACCGCAGAGCATCGTCTACTCGCTTCAGCTCTATGCCGATCTG
ATCCACGAGTTCCTTGAAAAAACCGGCGCAATCGCGCGGTGGCCGGTGTACGGTACCGGTCACTCGATGGGGGGAAAGTA
CTTGCTCGCGACCGCCCTGATTCATCCCGGAACGTTCGACAAAATGGTGTTGAGCAATACTGACGGCTTCGTCACCCTGC
CGTCATGGTCGAGAGCCATCAGCCTACCCGGCGTGCGTCACCTGCTCAAACCGCTGGTAACGACCGAAAAGATGTCCCGC
AAAATGTTCGATGCCGCCCTGTACAACCGGCAGGCAATCGACCGAGGGCTCTACCGGAAGCTGCTCGGAATTGCACGTGA
CCACGGAGCCTTCGACACGACCATGAAGCTGAACCGGAACATGCCGCTGCTCGACATGCAGCGCACTGGCCTGCGTTCGA
GGCTTGGCGAGTTGACGCAGCCTGTACTGATCATCTGGGGCGACCATGACCAGTATATTTCACCGAAAATCGCCCCTGTG
GTCAAGCAAGAGCTGCCCACATCAAAGCTGATCGTCTTCAGGGATTGCGGCCACTGCCCTATGCTTGAATACCCGGAAAA
GTTCAGCTCGGCGGTCAAAAATTTTATTTTTGAGGAAACACCAGCGCATTAA

Upstream 100 bases:

>100_bases
GCCGCCGTAACGGTTTTTTGCCGTTCATTGCTTATTTTGCTTTTACTTCCCGTTCAACCCTCGCAACAACACCTCTTTGT
GATCATAATGCCCTCTGGCA

Downstream 100 bases:

>100_bases
GACTTATGCTTATCACCTTCGAAGGAATCGACGGCGCAGGAAAATCGACCCAGGTCGTCAAGCTGAAACGCCATCTCCAG
GAACGCGGCCGTGAGGTGCT

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MAAQDRYITLSGHRHRYLDTGGNAPVMLLLHGISASFDFYDPVIPQLAGSFRVLGLDLLGFGGSDKPQSIVYSLQLYADL
IHEFLEKTGAIARWPVYGTGHSMGGKYLLATALIHPGTFDKMVLSNTDGFVTLPSWSRAISLPGVRHLLKPLVTTEKMSR
KMFDAALYNRQAIDRGLYRKLLGIARDHGAFDTTMKLNRNMPLLDMQRTGLRSRLGELTQPVLIIWGDHDQYISPKIAPV
VKQELPTSKLIVFRDCGHCPMLEYPEKFSSAVKNFIFEETPAH

Sequences:

>Translated_283_residues
MAAQDRYITLSGHRHRYLDTGGNAPVMLLLHGISASFDFYDPVIPQLAGSFRVLGLDLLGFGGSDKPQSIVYSLQLYADL
IHEFLEKTGAIARWPVYGTGHSMGGKYLLATALIHPGTFDKMVLSNTDGFVTLPSWSRAISLPGVRHLLKPLVTTEKMSR
KMFDAALYNRQAIDRGLYRKLLGIARDHGAFDTTMKLNRNMPLLDMQRTGLRSRLGELTQPVLIIWGDHDQYISPKIAPV
VKQELPTSKLIVFRDCGHCPMLEYPEKFSSAVKNFIFEETPAH
>Mature_282_residues
AAQDRYITLSGHRHRYLDTGGNAPVMLLLHGISASFDFYDPVIPQLAGSFRVLGLDLLGFGGSDKPQSIVYSLQLYADLI
HEFLEKTGAIARWPVYGTGHSMGGKYLLATALIHPGTFDKMVLSNTDGFVTLPSWSRAISLPGVRHLLKPLVTTEKMSRK
MFDAALYNRQAIDRGLYRKLLGIARDHGAFDTTMKLNRNMPLLDMQRTGLRSRLGELTQPVLIIWGDHDQYISPKIAPVV
KQELPTSKLIVFRDCGHCPMLEYPEKFSSAVKNFIFEETPAH

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipase/esterase LIP3/BchO family [H]

Homologues:

Organism=Homo sapiens, GI189027141, Length=289, Percent_Identity=24.2214532871972, Blast_Score=76, Evalue=3e-14,
Organism=Escherichia coli, GI87081721, Length=298, Percent_Identity=24.8322147651007, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 31659; Mature: 31528

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAQDRYITLSGHRHRYLDTGGNAPVMLLLHGISASFDFYDPVIPQLAGSFRVLGLDLLG
CCCCCCEEEECCCCEEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHCCCEEEEEEEEEC
FGGSDKPQSIVYSLQLYADLIHEFLEKTGAIARWPVYGTGHSMGGKYLLATALIHPGTFD
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCEEECCCCCCCCEEEHHHHHCCCCCC
KMVLSNTDGFVTLPSWSRAISLPGVRHLLKPLVTTEKMSRKMFDAALYNRQAIDRGLYRK
HHEEECCCCEEECCCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGIARDHGAFDTTMKLNRNMPLLDMQRTGLRSRLGELTQPVLIIWGDHDQYISPKIAPV
HHHHHHCCCCCCCEEEECCCCCEEHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHH
VKQELPTSKLIVFRDCGHCPMLEYPEKFSSAVKNFIFEETPAH
HHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AAQDRYITLSGHRHRYLDTGGNAPVMLLLHGISASFDFYDPVIPQLAGSFRVLGLDLLG
CCCCCEEEECCCCEEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHCCCEEEEEEEEEC
FGGSDKPQSIVYSLQLYADLIHEFLEKTGAIARWPVYGTGHSMGGKYLLATALIHPGTFD
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCEEECCCCCCCCEEEHHHHHCCCCCC
KMVLSNTDGFVTLPSWSRAISLPGVRHLLKPLVTTEKMSRKMFDAALYNRQAIDRGLYRK
HHEEECCCCEEECCCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGIARDHGAFDTTMKLNRNMPLLDMQRTGLRSRLGELTQPVLIIWGDHDQYISPKIAPV
HHHHHHCCCCCCCEEEECCCCCEEHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHH
VKQELPTSKLIVFRDCGHCPMLEYPEKFSSAVKNFIFEETPAH
HHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2001407 [H]