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The map label for this gene is 192289437

Identifier: 192289437

GI number: 192289437

Start: 1073003

End: 1074037

Strand: Reverse

Name: 192289437

Synonym: Rpal_1010

Alternate gene names: NA

Gene position: 1074037-1073003 (Counterclockwise)

Preceding gene: 192289438

Following gene: 192289436

Centisome position: 18.7

GC content: 65.89

Gene sequence:

>1035_bases
ATGAACCTCGCTGACTTGAACCAGATCGCTCGCGCCATGGTCGCGCCCGGCAAAGGCATTCTCGCCGCCGACGAGTCCTC
GGGGACGATCAAGAAGCGGTTCGACGTCATCGGGGTGGAGTCGACCGAGACCAACCGCCGCGACTATCGCGAGATGCTGT
TCCGCTCCAAGGAAGCGATGAGCGACTACGTCTCCGGCGTGATCCTGTACGACGAGACGATCTGGCAGAACGCCGCCGAC
GGCACCCCGCTGGTGAAGCTGATCGAGCAGGCCGGCAGCATTCCGGGCATCAAGGTCGACGAGGGCACTCAGCCGCTGCC
GAACTGCCCGGGCGAGACCATCACGGTCGGCCTCGACAAGCTCGCCGAGCGGCTCGCTAAGTACTACAAGCAGGGCGCCC
GCTTCGCGAAGTGGCGCGCGGTGATCGACATCGATACCGCCCGCGGCGTTCCGAGCCACACCGCGATCATGACCAACGCC
CATGCGCTGGCGCGCTACGCGGCGCTGTGCCAGCAGGCCCAGATCGTGCCGATCGTCGAGCCGGAGGTGCTGATGGACGG
CGCCCACGACATCGACACCTGCTACAGCATCACCGAATGGGTGCTGAAGGAAACCTTCCAGCAACTGTACTTCCAGCGCG
TCGCCCTTGAAGGCATGATCCTGAAGCCGAACATGGCTGTCCCCGGCAAGAAATCGGCTAAGAAGGCGTCGGTGCAGGAA
GTCGCCGAGAAAACCGTGAAGCTGCTGAAGGCCTGCGTGCCGTCGGCGGTGCCGGGCATCGCCTTCCTGTCCGGCGGCCA
GTCGGACGAAGAAGCGACGGCCCACCTCGATGCCATGAACAAGATCGGTGGCCTGCCCTGGGGCCTCACCTTCTCGTACG
GCCGTGCCCTGCAGGCCGCGCCGCAGAAGGCGTGGTCGGGCAAGGCCGAAAACGTCGCGGCCGGTCAGGCCGCGTTCACC
CACCGGGCCCGGATGAACTCGCTCGCCGCCAAGGGCGAGTGGAGCGCCGAGCTCGAAACCAAGAAGGCCGCCTGA

Upstream 100 bases:

>100_bases
GGCCGCGGTCAATCGCGCCCTCGCCATCTTCCTCGGCATTGTCTAAGACCCTGTCCGAACGGCTTCCCAAACCAACAAGA
ACAGCCAAAGGAGAGACGCG

Downstream 100 bases:

>100_bases
GCCGTATGAACGCCAAGCCTGCTCCATCGCGTCCGGCGCCGCGCCTGTATCTGGCGACGCCGGTGACTGCCGATCCCGCC
GCCGTGGCCGCGGCCCTGCC

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: Fructose-biphosphate aldolase class I; FBP aldolase [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MNLADLNQIARAMVAPGKGILAADESSGTIKKRFDVIGVESTETNRRDYREMLFRSKEAMSDYVSGVILYDETIWQNAAD
GTPLVKLIEQAGSIPGIKVDEGTQPLPNCPGETITVGLDKLAERLAKYYKQGARFAKWRAVIDIDTARGVPSHTAIMTNA
HALARYAALCQQAQIVPIVEPEVLMDGAHDIDTCYSITEWVLKETFQQLYFQRVALEGMILKPNMAVPGKKSAKKASVQE
VAEKTVKLLKACVPSAVPGIAFLSGGQSDEEATAHLDAMNKIGGLPWGLTFSYGRALQAAPQKAWSGKAENVAAGQAAFT
HRARMNSLAAKGEWSAELETKKAA

Sequences:

>Translated_344_residues
MNLADLNQIARAMVAPGKGILAADESSGTIKKRFDVIGVESTETNRRDYREMLFRSKEAMSDYVSGVILYDETIWQNAAD
GTPLVKLIEQAGSIPGIKVDEGTQPLPNCPGETITVGLDKLAERLAKYYKQGARFAKWRAVIDIDTARGVPSHTAIMTNA
HALARYAALCQQAQIVPIVEPEVLMDGAHDIDTCYSITEWVLKETFQQLYFQRVALEGMILKPNMAVPGKKSAKKASVQE
VAEKTVKLLKACVPSAVPGIAFLSGGQSDEEATAHLDAMNKIGGLPWGLTFSYGRALQAAPQKAWSGKAENVAAGQAAFT
HRARMNSLAAKGEWSAELETKKAA
>Mature_344_residues
MNLADLNQIARAMVAPGKGILAADESSGTIKKRFDVIGVESTETNRRDYREMLFRSKEAMSDYVSGVILYDETIWQNAAD
GTPLVKLIEQAGSIPGIKVDEGTQPLPNCPGETITVGLDKLAERLAKYYKQGARFAKWRAVIDIDTARGVPSHTAIMTNA
HALARYAALCQQAQIVPIVEPEVLMDGAHDIDTCYSITEWVLKETFQQLYFQRVALEGMILKPNMAVPGKKSAKKASVQE
VAEKTVKLLKACVPSAVPGIAFLSGGQSDEEATAHLDAMNKIGGLPWGLTFSYGRALQAAPQKAWSGKAENVAAGQAAFT
HRARMNSLAAKGEWSAELETKKAA

Specific function: Unknown

COG id: COG3588

COG function: function code G; Fructose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class I fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Homo sapiens, GI34577112, Length=332, Percent_Identity=52.710843373494, Blast_Score=342, Evalue=2e-94,
Organism=Homo sapiens, GI34577110, Length=332, Percent_Identity=52.710843373494, Blast_Score=342, Evalue=2e-94,
Organism=Homo sapiens, GI4557305, Length=332, Percent_Identity=52.710843373494, Blast_Score=342, Evalue=2e-94,
Organism=Homo sapiens, GI193794814, Length=332, Percent_Identity=52.710843373494, Blast_Score=342, Evalue=2e-94,
Organism=Homo sapiens, GI4885063, Length=341, Percent_Identity=50.1466275659824, Blast_Score=330, Evalue=9e-91,
Organism=Homo sapiens, GI40354205, Length=332, Percent_Identity=49.6987951807229, Blast_Score=310, Evalue=1e-84,
Organism=Caenorhabditis elegans, GI71983985, Length=331, Percent_Identity=51.6616314199396, Blast_Score=332, Evalue=1e-91,
Organism=Caenorhabditis elegans, GI25150450, Length=333, Percent_Identity=50.4504504504504, Blast_Score=330, Evalue=6e-91,
Organism=Caenorhabditis elegans, GI71983990, Length=233, Percent_Identity=51.0729613733906, Blast_Score=234, Evalue=7e-62,
Organism=Drosophila melanogaster, GI221459619, Length=333, Percent_Identity=52.2522522522522, Blast_Score=339, Evalue=1e-93,
Organism=Drosophila melanogaster, GI24650288, Length=333, Percent_Identity=52.2522522522522, Blast_Score=339, Evalue=1e-93,
Organism=Drosophila melanogaster, GI24650282, Length=331, Percent_Identity=52.2658610271903, Blast_Score=339, Evalue=2e-93,
Organism=Drosophila melanogaster, GI24650280, Length=331, Percent_Identity=52.2658610271903, Blast_Score=339, Evalue=2e-93,
Organism=Drosophila melanogaster, GI24650278, Length=331, Percent_Identity=52.2658610271903, Blast_Score=339, Evalue=2e-93,
Organism=Drosophila melanogaster, GI45553577, Length=331, Percent_Identity=52.2658610271903, Blast_Score=338, Evalue=3e-93,
Organism=Drosophila melanogaster, GI24650304, Length=331, Percent_Identity=45.0151057401813, Blast_Score=300, Evalue=8e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000741
- InterPro:   IPR013785 [H]

Pfam domain/function: PF00274 Glycolytic [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 37223; Mature: 37223

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLADLNQIARAMVAPGKGILAADESSGTIKKRFDVIGVESTETNRRDYREMLFRSKEAM
CCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHEEEECCCCCCHHHHHHHHHHHHHHHH
SDYVSGVILYDETIWQNAADGTPLVKLIEQAGSIPGIKVDEGTQPLPNCPGETITVGLDK
HHHHCEEEEECHHHHCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCCCCEEEECHHH
LAERLAKYYKQGARFAKWRAVIDIDTARGVPSHTAIMTNAHALARYAALCQQAQIVPIVE
HHHHHHHHHHHCCHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEECC
PEVLMDGAHDIDTCYSITEWVLKETFQQLYFQRVALEGMILKPNMAVPGKKSAKKASVQE
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHH
VAEKTVKLLKACVPSAVPGIAFLSGGQSDEEATAHLDAMNKIGGLPWGLTFSYGRALQAA
HHHHHHHHHHHHHHHCCCCHHEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
PQKAWSGKAENVAAGQAAFTHRARMNSLAAKGEWSAELETKKAA
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNLADLNQIARAMVAPGKGILAADESSGTIKKRFDVIGVESTETNRRDYREMLFRSKEAM
CCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHEEEECCCCCCHHHHHHHHHHHHHHHH
SDYVSGVILYDETIWQNAADGTPLVKLIEQAGSIPGIKVDEGTQPLPNCPGETITVGLDK
HHHHCEEEEECHHHHCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCCCCEEEECHHH
LAERLAKYYKQGARFAKWRAVIDIDTARGVPSHTAIMTNAHALARYAALCQQAQIVPIVE
HHHHHHHHHHHCCHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEECC
PEVLMDGAHDIDTCYSITEWVLKETFQQLYFQRVALEGMILKPNMAVPGKKSAKKASVQE
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHH
VAEKTVKLLKACVPSAVPGIAFLSGGQSDEEATAHLDAMNKIGGLPWGLTFSYGRALQAA
HHHHHHHHHHHHHHHCCCCHHEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
PQKAWSGKAENVAAGQAAFTHRARMNSLAAKGEWSAELETKKAA
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]