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The map label for this gene is dapD

Identifier: 192289060

GI number: 192289060

Start: 683704

End: 684549

Strand: Reverse

Name: dapD

Synonym: Rpal_0630

Alternate gene names: 192289060

Gene position: 684549-683704 (Counterclockwise)

Preceding gene: 192289061

Following gene: 192289059

Centisome position: 11.92

GC content: 67.02

Gene sequence:

>846_bases
ATGCCGCTCACCGCCCTGGAATCCACCATCAACGCCGCTTTCGACGCGCGCGACACCGTCACCGCGGCGACGCAGGGCGA
GATTCGCCAGGCCGTTGAGGACGCGCTCGATCTGCTCGATCAGGGCAAGGTGCGGGTCGCGCAGCGTGATGCCTCCGGCG
CTTGGACGGTCAATCAGTGGCTGAAGAAGGCGGTGCTGCTGTCGTTCCGGCTCAACGACATGGGCGTGATCGCCGGCGGG
CCGGGGGGTGCCAACTGGTGGGACAAGGTGCCGTCGAAGTTCGAGGGCTGGGGTGAGAACCGCTTCCGCGAAGCCGGCTT
CCGCGCGGTGCCGGGCGCGATCGTGCGCCGCTCTGCCTTTATCGCCAAGAACGCAGTGCTGATGCCGTCGTTCGTCAATC
TCGGCGCTTACGTCGATGAAAGCACCATGGTCGACACCTGGGCGACCGTTGGCTCCTGCGCCCAGATCGGTAAGCGCGTG
CACATCTCCGGCGGCGCCGGCATCGGCGGGGTACTCGAGCCGCTGCAGGCCGGACCGGTGATCATCGAGGATGACTGCTT
CATCGGCGCGCGCTCCGAGGTCGCCGAGGGCGTGATCGTCCGCAAGGGTGCAGTGCTGGCGATGGGGGTTTTCCTCGGTG
CGTCGACCAAGATCGTCGACCGCGAGACCGGCGAAGTCTTCGTTGGTGAAGTGCCGGAATATGCCGTGCTGGTGCCCGGC
ACCCTGCCCGGCAAGCCGATGAAGAACGGCGCCCCCGGCCCGGCCACCGCCTGCGCGGTGATCGTCAAGCGCGTCGACGA
GCGCACCCGTTCCAAGACCTCGATCAACGAATTGCTGCGAGACTGA

Upstream 100 bases:

>100_bases
CCACTTCAGCGCCCCTCGCCCAGCCTTGACTCTCTCTGGTCGAATCCGGACAACACTCCGCAAAACTCTCCCTGAAATCA
GCCTTCCCAAGGACCCGTCG

Downstream 100 bases:

>100_bases
CACCCAGAGGAGGCGCGGATGGACTGGACCACGCTGTTCTTCAGCTTTCGAGGTCGCATCAACCGCGCCAAATACTGGCT
GGTCGGACTGATCTACGTCG

Product: 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MPLTALESTINAAFDARDTVTAATQGEIRQAVEDALDLLDQGKVRVAQRDASGAWTVNQWLKKAVLLSFRLNDMGVIAGG
PGGANWWDKVPSKFEGWGENRFREAGFRAVPGAIVRRSAFIAKNAVLMPSFVNLGAYVDESTMVDTWATVGSCAQIGKRV
HISGGAGIGGVLEPLQAGPVIIEDDCFIGARSEVAEGVIVRKGAVLAMGVFLGASTKIVDRETGEVFVGEVPEYAVLVPG
TLPGKPMKNGAPGPATACAVIVKRVDERTRSKTSINELLRD

Sequences:

>Translated_281_residues
MPLTALESTINAAFDARDTVTAATQGEIRQAVEDALDLLDQGKVRVAQRDASGAWTVNQWLKKAVLLSFRLNDMGVIAGG
PGGANWWDKVPSKFEGWGENRFREAGFRAVPGAIVRRSAFIAKNAVLMPSFVNLGAYVDESTMVDTWATVGSCAQIGKRV
HISGGAGIGGVLEPLQAGPVIIEDDCFIGARSEVAEGVIVRKGAVLAMGVFLGASTKIVDRETGEVFVGEVPEYAVLVPG
TLPGKPMKNGAPGPATACAVIVKRVDERTRSKTSINELLRD
>Mature_280_residues
PLTALESTINAAFDARDTVTAATQGEIRQAVEDALDLLDQGKVRVAQRDASGAWTVNQWLKKAVLLSFRLNDMGVIAGGP
GGANWWDKVPSKFEGWGENRFREAGFRAVPGAIVRRSAFIAKNAVLMPSFVNLGAYVDESTMVDTWATVGSCAQIGKRVH
ISGGAGIGGVLEPLQAGPVIIEDDCFIGARSEVAEGVIVRKGAVLAMGVFLGASTKIVDRETGEVFVGEVPEYAVLVPGT
LPGKPMKNGAPGPATACAVIVKRVDERTRSKTSINELLRD

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family

Homologues:

Organism=Escherichia coli, GI1786362, Length=279, Percent_Identity=59.1397849462366, Blast_Score=304, Evalue=5e-84,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPD_RHOPA (Q6NC47)

Other databases:

- EMBL:   BX572594
- RefSeq:   NP_945979.1
- ProteinModelPortal:   Q6NC47
- SMR:   Q6NC47
- GeneID:   2692704
- GenomeReviews:   BX571963_GR
- KEGG:   rpa:RPA0626
- NMPDR:   fig|258594.1.peg.623
- HOGENOM:   HBG704071
- OMA:   QWAKKAV
- ProtClustDB:   PRK11830
- BioCyc:   RPAL258594:RPA0626-MONOMER
- BRENDA:   2.3.1.117
- GO:   GO:0005737
- HAMAP:   MF_00811
- InterPro:   IPR005664
- InterPro:   IPR023180
- InterPro:   IPR011004
- Gene3D:   G3DSA:1.10.166.10
- TIGRFAMs:   TIGR00965

Pfam domain/function: SSF51161 Trimer_LpxA_like

EC number: =2.3.1.117

Molecular weight: Translated: 29734; Mature: 29603

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: BINDING 108-108 BINDING 145-145

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLTALESTINAAFDARDTVTAATQGEIRQAVEDALDLLDQGKVRVAQRDASGAWTVNQW
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHH
LKKAVLLSFRLNDMGVIAGGPGGANWWDKVPSKFEGWGENRFREAGFRAVPGAIVRRSAF
HHHHHHHHEEECCCEEEECCCCCCCHHHHCCHHHCCCCCHHHHHCCCCCCCHHHHHHHHH
IAKNAVLMPSFVNLGAYVDESTMVDTWATVGSCAQIGKRVHISGGAGIGGVLEPLQAGPV
HHCCCEECCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHCCCE
IIEDDCFIGARSEVAEGVIVRKGAVLAMGVFLGASTKIVDRETGEVFVGEVPEYAVLVPG
EEECCCCCCCHHHHHCCEEEECCHHHHHHHHHCCCCEEEECCCCCEEECCCCCEEEEECC
TLPGKPMKNGAPGPATACAVIVKRVDERTRSKTSINELLRD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PLTALESTINAAFDARDTVTAATQGEIRQAVEDALDLLDQGKVRVAQRDASGAWTVNQW
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHH
LKKAVLLSFRLNDMGVIAGGPGGANWWDKVPSKFEGWGENRFREAGFRAVPGAIVRRSAF
HHHHHHHHEEECCCEEEECCCCCCCHHHHCCHHHCCCCCHHHHHCCCCCCCHHHHHHHHH
IAKNAVLMPSFVNLGAYVDESTMVDTWATVGSCAQIGKRVHISGGAGIGGVLEPLQAGPV
HHCCCEECCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHCCCE
IIEDDCFIGARSEVAEGVIVRKGAVLAMGVFLGASTKIVDRETGEVFVGEVPEYAVLVPG
EEECCCCCCCHHHHHCCEEEECCHHHHHHHHHCCCCEEEECCCCCEEECCCCCEEEEECC
TLPGKPMKNGAPGPATACAVIVKRVDERTRSKTSINELLRD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA