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The map label for this gene is frr

Identifier: 190571622

GI number: 190571622

Start: 1317785

End: 1318342

Strand: Direct

Name: frr

Synonym: WPa_1246

Alternate gene names: 190571622

Gene position: 1317785-1318342 (Clockwise)

Preceding gene: 190571621

Following gene: 190571623

Centisome position: 88.89

GC content: 31.36

Gene sequence:

>558_bases
ATGTTAAACGAAATAAAAGCTAAAACAAAAGAAAGAATGCTAAAAACTATTCAGTCTTTTCACGATGATATGAAAGGTGT
ACGTACTGGTAGAGCTAACGCATCATTACTTGATGGTATAGTTGTAAATATCTATGGTGGACATCAAAAACTGAACCAAG
TTGCAGGAGTTTCAGCTATAGATAACAAAACTCTATCAGTTAAAGTTTGGGATGCTACTGCTATCGGTGAAGTAAAAAAT
GCGATAATCAATGCTAACCTGAATTTAAATCCTGTTGTTGAAGGAAATACTATACGTATAGTTCTTCCAGACTTAACACA
AGAAACTCGTGAAAAATTAGTGAAACTATTGCATCAATTTTCTGAAAATGCACGAGTTGCAATTAGAAATATACGCAGAG
ATGTTATGGAAGAAATAGAGGAAATGAAGAAAAATAAGGAAATCTCAGAAGATGATTTTCATGTTGCCAAAAAGGAAATA
CAAAACATTACTGATGATAATGTAAAAAAAGTCGATGATGACTTATCTATTAAAGAAAAGGATATATTGCATCATTAA

Upstream 100 bases:

>100_bases
CCAATTGTAGTTTTTTCTTTAAAAAGAGAAAAAATGGTTGATATTATTAAGGGTCAAGGCACTTATACTATAGTTTCAGA
TTGTAAACATTAGGTAATTT

Downstream 100 bases:

>100_bases
GTTAATATGAAAGAATTTTTCAGTATTGAAAAACATAAGAGGATTCGATATAGATACAGTTGTATGAATGCTGTGATTCA
GATCTCATCATTACGCACAC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MLNEIKAKTKERMLKTIQSFHDDMKGVRTGRANASLLDGIVVNIYGGHQKLNQVAGVSAIDNKTLSVKVWDATAIGEVKN
AIINANLNLNPVVEGNTIRIVLPDLTQETREKLVKLLHQFSENARVAIRNIRRDVMEEIEEMKKNKEISEDDFHVAKKEI
QNITDDNVKKVDDDLSIKEKDILHH

Sequences:

>Translated_185_residues
MLNEIKAKTKERMLKTIQSFHDDMKGVRTGRANASLLDGIVVNIYGGHQKLNQVAGVSAIDNKTLSVKVWDATAIGEVKN
AIINANLNLNPVVEGNTIRIVLPDLTQETREKLVKLLHQFSENARVAIRNIRRDVMEEIEEMKKNKEISEDDFHVAKKEI
QNITDDNVKKVDDDLSIKEKDILHH
>Mature_185_residues
MLNEIKAKTKERMLKTIQSFHDDMKGVRTGRANASLLDGIVVNIYGGHQKLNQVAGVSAIDNKTLSVKVWDATAIGEVKN
AIINANLNLNPVVEGNTIRIVLPDLTQETREKLVKLLHQFSENARVAIRNIRRDVMEEIEEMKKNKEISEDDFHVAKKEI
QNITDDNVKKVDDDLSIKEKDILHH

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=178, Percent_Identity=32.5842696629214, Blast_Score=84, Evalue=6e-17,
Organism=Homo sapiens, GI291042689, Length=160, Percent_Identity=35.625, Blast_Score=81, Evalue=7e-16,
Organism=Escherichia coli, GI1786368, Length=185, Percent_Identity=40, Blast_Score=150, Evalue=6e-38,
Organism=Drosophila melanogaster, GI24661488, Length=173, Percent_Identity=28.3236994219653, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_WOLPP (B3CNH2)

Other databases:

- EMBL:   AM999887
- RefSeq:   YP_001975980.1
- EnsemblBacteria:   EBWOLT00000000602
- GeneID:   6384543
- GenomeReviews:   AM999887_GR
- KEGG:   wpi:WPa_1246
- GeneTree:   EBGT00050000031355
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20957; Mature: 20957

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNEIKAKTKERMLKTIQSFHDDMKGVRTGRANASLLDGIVVNIYGGHQKLNQVAGVSAI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCEEEEEECCHHHHHHHHCCHHC
DNKTLSVKVWDATAIGEVKNAIINANLNLNPVVEGNTIRIVLPDLTQETREKLVKLLHQF
CCCEEEEEEECCHHHHHHHHHHEECCCCCCEEEECCEEEEEECCCCHHHHHHHHHHHHHH
SENARVAIRNIRRDVMEEIEEMKKNKEISEDDFHVAKKEIQNITDDNVKKVDDDLSIKEK
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCCCCHH
DILHH
HHCCC
>Mature Secondary Structure
MLNEIKAKTKERMLKTIQSFHDDMKGVRTGRANASLLDGIVVNIYGGHQKLNQVAGVSAI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCEEEEEECCHHHHHHHHCCHHC
DNKTLSVKVWDATAIGEVKNAIINANLNLNPVVEGNTIRIVLPDLTQETREKLVKLLHQF
CCCEEEEEEECCHHHHHHHHHHEECCCCCCEEEECCEEEEEECCCCHHHHHHHHHHHHHH
SENARVAIRNIRRDVMEEIEEMKKNKEISEDDFHVAKKEIQNITDDNVKKVDDDLSIKEK
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCCCCHH
DILHH
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA