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The map label for this gene is argS [H]

Identifier: 190571604

GI number: 190571604

Start: 1300250

End: 1301950

Strand: Direct

Name: argS [H]

Synonym: WPa_1227

Alternate gene names: 190571604

Gene position: 1300250-1301950 (Clockwise)

Preceding gene: 190571603

Following gene: 190571607

Centisome position: 87.71

GC content: 38.39

Gene sequence:

>1701_bases
ATGAACATTTTCAAGCAGATTTCCTCTCTAATTTCCAGCAAATTAAATGAGTTGAAACAAAGGGGTGTCATAAATACAAG
TGCAGAAAATTTTATTGTGGAACCTCCAAGCAATAGAGCACATGGTGATATTTACACAAATGTTGCTATGGTGCTTGCAA
AGCATGAAAAAAAGAATCCAATTGAGATTGCAGGGATCTTAGCAAGAGAATTTAAACCTTTTGATGAAGTTGCAGAAGTG
GAAATAGCAAGCCCCGGTTTTATCAATATGCACTTAAAAATAGAAGTGTGGCATGGGATTTTAAAACAAATAAATGAGCT
AAAAACAGAGTTTGGCACTCTAAATATTGGAAATAATCAAGCTGTCAATGTTGAATTTGTATCGGCAAATCCAACAGGTC
CTCTGCATATTGGTCATGCAAGAGGGGCAGTGTTTGGTGATGTTCTGGCAAATTTACTAAAGAAAGTTGGCTATAATGTT
ACTAAGGAGTACTATATCAATGACGCTGGAGCGCAGATAGATACGCTAATTCGGTCAGTATATTTGCGGTATAAGGAAGC
TCTGGGAGAAAAAATTAGCATTGAAAAGGGTTTATACCCAGGTGAATATTTAAAGCCAATAGGAGAGGGATTAGCTAAAA
AATATGGCAAGGAGCTTAGAGCAGAGGAAGATAACCAGATAATTAGAGAATATACTTTAAGTTCTATTTTAGAACTCATA
AAGGAGGACATGAGCTTGCTTGGAGTAAATCATGATGTCTTTACTTCAGAGTATGAGCTACGTGGCAAAATCGAAGAGAG
TATAAAGATATTATCTGACAAGGGTCTAGTGTATGAAGGGTACCTGGAGAAACCAAAAGGCAAAGAAAGTGAAAATTGGA
CTTCCAGAAAAGAAATGTTATTTCGCTCTACAAAATTTGGCGATGATGTTGACCGCGCATTGAAGAAAGAGGACGGCAGT
TGGACTTATTTTGCCTCAGATATCGCTTACCATTTTGATAAGATATCGCGTGGTTTTAACAATATGATCGTAGAGCTTGG
TAGTGACCACGGTGGTTATGTCAAAAGGCTAAAAGCAGTCGTCTCTGCGCTCAGTGATGATCAAGCAAAAATAGAGGTAA
AACTGCATAATATTGTGAATTTTTTCGAGAATGAAAAACCTGTTAAGATGTCCAAAAGATCAGGAAACTTCCTAACAGCA
AGAGATGTAGTGGAGGAAGTTGGCAGGGATATCACTCGTTTTATAATGCTGACACGCAAGAATGATATGGTCTTGGACTT
TGATTTTGCTAAAGTTAAAGAACAATCAAAAGACAACCCTATTTTTTATGTGCAATATGCGCACGCCCGTGCTCATTCGT
TAATGCGTAATGCTCCAAAAGAGCTCCCAACAGCAGATCCTTCACTTTTAAAGACCGATGGGGAGCTCTTCCTCATAAAA
ATCTTAGCAAAGTGGCCAGATGTGGTAGAAATAGCGGCAAGGCTCTATGAGCCACACAGAATCACTTTCTACTTACTTGA
AGTTGCAGAAGCGTTTCACGTTTTATGGGGGTATGGCAAAAGTGATTTAAACATGCGGTTCATACTAGAAGATAACTTGA
ACCTCACCGCTGCAAGAATGTTTCTCGTACAAGCCTTAGCGCACGTAATCGCTTCTGGGCTTTCTATTTTTAATATAGAG
CCTTTGAAAGAGATGTGTTAA

Upstream 100 bases:

>100_bases
AAGGTTGCCTTACACCAAACAAAGAGTAGAGAGAAAATCATAACTTCAACTAGCCCCACTTATTTGCTATACTGCTATAG
ATTTTATAGCAGTATAGTGA

Downstream 100 bases:

>100_bases
TTTTAAGGCCAAAAATTATACAAGAGGTCTGTTAAAATCACGTATGTCGATTGTCTTGAAGTCACACAATTGTTCTGTAG
AGCTATGTCCTGTAATAATT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 566; Mature: 566

Protein sequence:

>566_residues
MNIFKQISSLISSKLNELKQRGVINTSAENFIVEPPSNRAHGDIYTNVAMVLAKHEKKNPIEIAGILAREFKPFDEVAEV
EIASPGFINMHLKIEVWHGILKQINELKTEFGTLNIGNNQAVNVEFVSANPTGPLHIGHARGAVFGDVLANLLKKVGYNV
TKEYYINDAGAQIDTLIRSVYLRYKEALGEKISIEKGLYPGEYLKPIGEGLAKKYGKELRAEEDNQIIREYTLSSILELI
KEDMSLLGVNHDVFTSEYELRGKIEESIKILSDKGLVYEGYLEKPKGKESENWTSRKEMLFRSTKFGDDVDRALKKEDGS
WTYFASDIAYHFDKISRGFNNMIVELGSDHGGYVKRLKAVVSALSDDQAKIEVKLHNIVNFFENEKPVKMSKRSGNFLTA
RDVVEEVGRDITRFIMLTRKNDMVLDFDFAKVKEQSKDNPIFYVQYAHARAHSLMRNAPKELPTADPSLLKTDGELFLIK
ILAKWPDVVEIAARLYEPHRITFYLLEVAEAFHVLWGYGKSDLNMRFILEDNLNLTAARMFLVQALAHVIASGLSIFNIE
PLKEMC

Sequences:

>Translated_566_residues
MNIFKQISSLISSKLNELKQRGVINTSAENFIVEPPSNRAHGDIYTNVAMVLAKHEKKNPIEIAGILAREFKPFDEVAEV
EIASPGFINMHLKIEVWHGILKQINELKTEFGTLNIGNNQAVNVEFVSANPTGPLHIGHARGAVFGDVLANLLKKVGYNV
TKEYYINDAGAQIDTLIRSVYLRYKEALGEKISIEKGLYPGEYLKPIGEGLAKKYGKELRAEEDNQIIREYTLSSILELI
KEDMSLLGVNHDVFTSEYELRGKIEESIKILSDKGLVYEGYLEKPKGKESENWTSRKEMLFRSTKFGDDVDRALKKEDGS
WTYFASDIAYHFDKISRGFNNMIVELGSDHGGYVKRLKAVVSALSDDQAKIEVKLHNIVNFFENEKPVKMSKRSGNFLTA
RDVVEEVGRDITRFIMLTRKNDMVLDFDFAKVKEQSKDNPIFYVQYAHARAHSLMRNAPKELPTADPSLLKTDGELFLIK
ILAKWPDVVEIAARLYEPHRITFYLLEVAEAFHVLWGYGKSDLNMRFILEDNLNLTAARMFLVQALAHVIASGLSIFNIE
PLKEMC
>Mature_566_residues
MNIFKQISSLISSKLNELKQRGVINTSAENFIVEPPSNRAHGDIYTNVAMVLAKHEKKNPIEIAGILAREFKPFDEVAEV
EIASPGFINMHLKIEVWHGILKQINELKTEFGTLNIGNNQAVNVEFVSANPTGPLHIGHARGAVFGDVLANLLKKVGYNV
TKEYYINDAGAQIDTLIRSVYLRYKEALGEKISIEKGLYPGEYLKPIGEGLAKKYGKELRAEEDNQIIREYTLSSILELI
KEDMSLLGVNHDVFTSEYELRGKIEESIKILSDKGLVYEGYLEKPKGKESENWTSRKEMLFRSTKFGDDVDRALKKEDGS
WTYFASDIAYHFDKISRGFNNMIVELGSDHGGYVKRLKAVVSALSDDQAKIEVKLHNIVNFFENEKPVKMSKRSGNFLTA
RDVVEEVGRDITRFIMLTRKNDMVLDFDFAKVKEQSKDNPIFYVQYAHARAHSLMRNAPKELPTADPSLLKTDGELFLIK
ILAKWPDVVEIAARLYEPHRITFYLLEVAEAFHVLWGYGKSDLNMRFILEDNLNLTAARMFLVQALAHVIASGLSIFNIE
PLKEMC

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=596, Percent_Identity=24.496644295302, Blast_Score=94, Evalue=4e-19,
Organism=Escherichia coli, GI1788184, Length=570, Percent_Identity=22.280701754386, Blast_Score=79, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71985061, Length=598, Percent_Identity=23.4113712374582, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71985068, Length=545, Percent_Identity=24.4036697247706, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320548, Length=566, Percent_Identity=24.3816254416961, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28571570, Length=505, Percent_Identity=22.970297029703, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 64191; Mature: 64191

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIFKQISSLISSKLNELKQRGVINTSAENFIVEPPSNRAHGDIYTNVAMVLAKHEKKNP
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCC
IEIAGILAREFKPFDEVAEVEIASPGFINMHLKIEVWHGILKQINELKTEFGTLNIGNNQ
HHHHHHHHHHCCCHHHHHHEEECCCCEEEEEEEEHHHHHHHHHHHHHHHHHCEEECCCCC
AVNVEFVSANPTGPLHIGHARGAVFGDVLANLLKKVGYNVTKEYYINDAGAQIDTLIRSV
EEEEEEEECCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHH
YLRYKEALGEKISIEKGLYPGEYLKPIGEGLAKKYGKELRAEEDNQIIREYTLSSILELI
HHHHHHHCCCEEEHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
KEDMSLLGVNHDVFTSEYELRGKIEESIKILSDKGLVYEGYLEKPKGKESENWTSRKEML
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCHHHHHHHH
FRSTKFGDDVDRALKKEDGSWTYFASDIAYHFDKISRGFNNMIVELGSDHGGYVKRLKAV
HHHCCCCCHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCHHHHHEEECCCCCHHHHHHHHH
VSALSDDQAKIEVKLHNIVNFFENEKPVKMSKRSGNFLTARDVVEEVGRDITRFIMLTRK
HHHHCCCCEEEEEEHHHHHHHHCCCCCCEECCCCCCEEHHHHHHHHHHHHHHHHHHEECC
NDMVLDFDFAKVKEQSKDNPIFYVQYAHARAHSLMRNAPKELPTADPSLLKTDGELFLIK
CCEEEECCHHHHHHCCCCCCEEEEEEHHHHHHHHHHCCHHHCCCCCCHHEECCCCEEEEH
ILAKWPDVVEIAARLYEPHRITFYLLEVAEAFHVLWGYGKSDLNMRFILEDNLNLTAARM
HHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHH
FLVQALAHVIASGLSIFNIEPLKEMC
HHHHHHHHHHHCCCCEEECCHHHHCC
>Mature Secondary Structure
MNIFKQISSLISSKLNELKQRGVINTSAENFIVEPPSNRAHGDIYTNVAMVLAKHEKKNP
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCC
IEIAGILAREFKPFDEVAEVEIASPGFINMHLKIEVWHGILKQINELKTEFGTLNIGNNQ
HHHHHHHHHHCCCHHHHHHEEECCCCEEEEEEEEHHHHHHHHHHHHHHHHHCEEECCCCC
AVNVEFVSANPTGPLHIGHARGAVFGDVLANLLKKVGYNVTKEYYINDAGAQIDTLIRSV
EEEEEEEECCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHH
YLRYKEALGEKISIEKGLYPGEYLKPIGEGLAKKYGKELRAEEDNQIIREYTLSSILELI
HHHHHHHCCCEEEHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
KEDMSLLGVNHDVFTSEYELRGKIEESIKILSDKGLVYEGYLEKPKGKESENWTSRKEML
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCHHHHHHHH
FRSTKFGDDVDRALKKEDGSWTYFASDIAYHFDKISRGFNNMIVELGSDHGGYVKRLKAV
HHHCCCCCHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCHHHHHEEECCCCCHHHHHHHHH
VSALSDDQAKIEVKLHNIVNFFENEKPVKMSKRSGNFLTARDVVEEVGRDITRFIMLTRK
HHHHCCCCEEEEEEHHHHHHHHCCCCCCEECCCCCCEEHHHHHHHHHHHHHHHHHHEECC
NDMVLDFDFAKVKEQSKDNPIFYVQYAHARAHSLMRNAPKELPTADPSLLKTDGELFLIK
CCEEEECCHHHHHHCCCCCCEEEEEEHHHHHHHHHHCCHHHCCCCCCHHEECCCCEEEEH
ILAKWPDVVEIAARLYEPHRITFYLLEVAEAFHVLWGYGKSDLNMRFILEDNLNLTAARM
HHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHH
FLVQALAHVIASGLSIFNIEPLKEMC
HHHHHHHHHHHCCCCEEECCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA