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The map label for this gene is pgsA [H]

Identifier: 190571589

GI number: 190571589

Start: 1285462

End: 1286004

Strand: Direct

Name: pgsA [H]

Synonym: WPa_1211

Alternate gene names: 190571589

Gene position: 1285462-1286004 (Clockwise)

Preceding gene: 190571584

Following gene: 190571590

Centisome position: 86.71

GC content: 35.36

Gene sequence:

>543_bases
ATGCTTAAGAAAAACGTGCCTAATTTGCTAACAATTTCTCGTGCGCTCGCAATACCGGCAATAATATCAAGCTTTTATAT
AGAGAGTAAGTATGCAAGTCTAATAACAATATTGATCTTTATGTTTGCGTGCATTACAGATTTTTTTGATGGTTATTTAG
CGCGTGCATGGAAAGTCCAATCGAATTTTGGCAAATTATTTGATCCAATTGCCGACAAGTTAGTAGTAGCTTCAACAATA
ATCATGCTAGTTTATAAGCATAAGATAGATGATATTACAATTATACCGTCAGTTATAATTGTTTGTAGGGAGATATTAGT
TTCAGGCTTGCGGGAGTTCTTGATAGCTACAAACGTTAGTTTACCTGTGAGTAAGGCTGGGAAAATTAAAACATTTTTGC
AGATGGTTGCTATAGTAGCGTTAATAATGAGTGATTATGAAGCAACTAAATATATAGGTGTGGTTTGCTTATGGGCTGCG
GCTGTTATGACTATGTGGTCAGGCTATAATTACGTTCTAGCTGGCATCAAACAGATTGACTAA

Upstream 100 bases:

>100_bases
ATTTCCTAAGTATATGGGGTTTTTATGAATGTTCAACTATTAGCTTGTGAACTCTATTGTACTTCTGTATAAATTTATCT
ACTACGTAGGGTGATGTGAC

Downstream 100 bases:

>100_bases
ATTGCTTAAGAGTATACAAAGAAAGTTAATAATTTCATAATATTGACTTAGTAATTAAAATCCTATATAATGTATTAGTT
CATAAGTTGGTCTGTTCATA

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MLKKNVPNLLTISRALAIPAIISSFYIESKYASLITILIFMFACITDFFDGYLARAWKVQSNFGKLFDPIADKLVVASTI
IMLVYKHKIDDITIIPSVIIVCREILVSGLREFLIATNVSLPVSKAGKIKTFLQMVAIVALIMSDYEATKYIGVVCLWAA
AVMTMWSGYNYVLAGIKQID

Sequences:

>Translated_180_residues
MLKKNVPNLLTISRALAIPAIISSFYIESKYASLITILIFMFACITDFFDGYLARAWKVQSNFGKLFDPIADKLVVASTI
IMLVYKHKIDDITIIPSVIIVCREILVSGLREFLIATNVSLPVSKAGKIKTFLQMVAIVALIMSDYEATKYIGVVCLWAA
AVMTMWSGYNYVLAGIKQID
>Mature_180_residues
MLKKNVPNLLTISRALAIPAIISSFYIESKYASLITILIFMFACITDFFDGYLARAWKVQSNFGKLFDPIADKLVVASTI
IMLVYKHKIDDITIIPSVIIVCREILVSGLREFLIATNVSLPVSKAGKIKTFLQMVAIVALIMSDYEATKYIGVVCLWAA
AVMTMWSGYNYVLAGIKQID

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=176, Percent_Identity=36.9318181818182, Blast_Score=123, Evalue=9e-30,
Organism=Saccharomyces cerevisiae, GI6320059, Length=104, Percent_Identity=34.6153846153846, Blast_Score=61, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24650130, Length=121, Percent_Identity=36.3636363636364, Blast_Score=63, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24650126, Length=121, Percent_Identity=36.3636363636364, Blast_Score=63, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24650128, Length=121, Percent_Identity=36.3636363636364, Blast_Score=63, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20026; Mature: 20026

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKNVPNLLTISRALAIPAIISSFYIESKYASLITILIFMFACITDFFDGYLARAWKVQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNFGKLFDPIADKLVVASTIIMLVYKHKIDDITIIPSVIIVCREILVSGLREFLIATNVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LPVSKAGKIKTFLQMVAIVALIMSDYEATKYIGVVCLWAAAVMTMWSGYNYVLAGIKQID
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure
MLKKNVPNLLTISRALAIPAIISSFYIESKYASLITILIFMFACITDFFDGYLARAWKVQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNFGKLFDPIADKLVVASTIIMLVYKHKIDDITIIPSVIIVCREILVSGLREFLIATNVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LPVSKAGKIKTFLQMVAIVALIMSDYEATKYIGVVCLWAAAVMTMWSGYNYVLAGIKQID
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA