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The map label for this gene is atpA [H]

Identifier: 190571573

GI number: 190571573

Start: 1267449

End: 1268990

Strand: Direct

Name: atpA [H]

Synonym: WPa_1193

Alternate gene names: 190571573

Gene position: 1267449-1268990 (Clockwise)

Preceding gene: 190571572

Following gene: 190571574

Centisome position: 85.5

GC content: 36.84

Gene sequence:

>1542_bases
ATGAAGAATAGCATAAATGCCTCTGAAGTAGTAAACATAATAAAAGAGAAGGTTGAGACATTTGATAATCCTATAAAACG
AGAAAATATAGGTGAAGTAATTTCAGTAACCGATGGTATCACATTGGTCTATGGGCTGGAAAAAGCAAAGTTTGGTGAAA
AGGTATCTTTTGCAAGCGGTGTAGAAGGAATAGTTCTTGATTTAGATCATGATACAGCTGGAATAGTTGTGCTTGGCAAT
GACCGTGATGTAAAAGAAGGGGACGTTGTAAAATGTAGTGGTGATGTTGTACAGGTGCCTGTAGGTCATGAATTATTAGG
GAGAGTTGTAAATGCATTAGGCGATCCTATAGACGATGGCGGAGAAATTAGAGCCAAGAACAAAATGTATATAGAATCTA
AAGCGCCAGGTATTATTGACCGTAAATCTGTGCATGAACCTCTGCAGACAGGAATTAAAATTATAGATTTGTTGATTCCT
ATAGGTAGAGGGCAACGTGAATTAATTATTGGCGATAGACAAATTGGTAAAACCACTATTGCGATTGATACTATTATCAA
TCAGAAGAAGATTAATGATGAGGTAAACGAAAATCAAAAAATTTACTGTGTTTATGTTGCTATTGGACAAAAAATTTCGA
CAGTAGCAAAAGTGGTGAATAAGCTAAAAGAAAGTGGAGCATTAGAGTATACAACCGTAGTTGTGGCTAGCGCATCTGAC
TGCGCGCCTATGCAATTTTTAGCACCTTATACCGGTTGCACTATTGGAGAATTTTTCCGTGATAATGGAATGCATTGCTT
GGTGGTATATGATGATTTATCTAAGCATGCTGTGGCATATAGGCAGATGTCCTTATTGCTCAGACGTCCTCCTGGTCGTG
AAGCTTATCCTGGAGATATATTCTATGTACACTCTCGCTTGCTTGAAAGAGCTGCCAAAATGTCTGATGAAAAAGGACAG
GGATCTTTGACTGCTTTGCCGATTATTGAGACTCAGGCTGGTGATGTATCTGCATATGTTCCAACTAATGTGATTTCAAT
TACCGATGGACAAATTTTTCTTGAGTCTGAATTGTTTCACAAAGGATTTCGCCCTGCAGTGAATATAGGTTTATCGGTTT
CTCGGGTTGGCTCTGCTGCACAATTGAAATCTGTGAAAAAAGTTGCTGGTTCTATAAAGCTGAGTTTGGCCCAATATAGA
GAACTGGAAGACTTTGCTAAATTTGGTTCTGATCTTGATGCTACTGTTCAATTGTCCTTAAACAAAGGTAAATACCTTAT
TGAATTATTAAAGCAAAAACAGTATTCACCTATGCAAATAGAAGAGCAAGTATTGCTTATGTATATCTTTTCTAATCTGT
ATGGTCAATTAAATAAGGTACAGGTGAGCAACATCAATAGGTTCGAGTGTGATCTTATCAATTATTTTCAAACTGTTCAC
CCTGGAGTTTTAAAAAAGTTGTCGGGTGACATGAATGATGATATAAAAGATGATATTCTTGGTATTGTGAGTGATTTTGT
CACTCAATTTAATTGCGTTTAG

Upstream 100 bases:

>100_bases
TTAGGTATGGTTTTAACGTGATTGATGCTTCGCTTAAGAGTTATTTGGATAGATTGGTTGATTTGAGTAAAATGGAAATG
TTGAAAATAAGGAATTGTAT

Downstream 100 bases:

>100_bases
GCGGTGATTATGACTTCATCCATTGTTAACAAGTTTCCTATTACAAGGGAAGGTTTTGAGAGTATGCAAGTCGAACTTGA
GAAATTAAAGGAAGAAAAAC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MKNSINASEVVNIIKEKVETFDNPIKRENIGEVISVTDGITLVYGLEKAKFGEKVSFASGVEGIVLDLDHDTAGIVVLGN
DRDVKEGDVVKCSGDVVQVPVGHELLGRVVNALGDPIDDGGEIRAKNKMYIESKAPGIIDRKSVHEPLQTGIKIIDLLIP
IGRGQRELIIGDRQIGKTTIAIDTIINQKKINDEVNENQKIYCVYVAIGQKISTVAKVVNKLKESGALEYTTVVVASASD
CAPMQFLAPYTGCTIGEFFRDNGMHCLVVYDDLSKHAVAYRQMSLLLRRPPGREAYPGDIFYVHSRLLERAAKMSDEKGQ
GSLTALPIIETQAGDVSAYVPTNVISITDGQIFLESELFHKGFRPAVNIGLSVSRVGSAAQLKSVKKVAGSIKLSLAQYR
ELEDFAKFGSDLDATVQLSLNKGKYLIELLKQKQYSPMQIEEQVLLMYIFSNLYGQLNKVQVSNINRFECDLINYFQTVH
PGVLKKLSGDMNDDIKDDILGIVSDFVTQFNCV

Sequences:

>Translated_513_residues
MKNSINASEVVNIIKEKVETFDNPIKRENIGEVISVTDGITLVYGLEKAKFGEKVSFASGVEGIVLDLDHDTAGIVVLGN
DRDVKEGDVVKCSGDVVQVPVGHELLGRVVNALGDPIDDGGEIRAKNKMYIESKAPGIIDRKSVHEPLQTGIKIIDLLIP
IGRGQRELIIGDRQIGKTTIAIDTIINQKKINDEVNENQKIYCVYVAIGQKISTVAKVVNKLKESGALEYTTVVVASASD
CAPMQFLAPYTGCTIGEFFRDNGMHCLVVYDDLSKHAVAYRQMSLLLRRPPGREAYPGDIFYVHSRLLERAAKMSDEKGQ
GSLTALPIIETQAGDVSAYVPTNVISITDGQIFLESELFHKGFRPAVNIGLSVSRVGSAAQLKSVKKVAGSIKLSLAQYR
ELEDFAKFGSDLDATVQLSLNKGKYLIELLKQKQYSPMQIEEQVLLMYIFSNLYGQLNKVQVSNINRFECDLINYFQTVH
PGVLKKLSGDMNDDIKDDILGIVSDFVTQFNCV
>Mature_513_residues
MKNSINASEVVNIIKEKVETFDNPIKRENIGEVISVTDGITLVYGLEKAKFGEKVSFASGVEGIVLDLDHDTAGIVVLGN
DRDVKEGDVVKCSGDVVQVPVGHELLGRVVNALGDPIDDGGEIRAKNKMYIESKAPGIIDRKSVHEPLQTGIKIIDLLIP
IGRGQRELIIGDRQIGKTTIAIDTIINQKKINDEVNENQKIYCVYVAIGQKISTVAKVVNKLKESGALEYTTVVVASASD
CAPMQFLAPYTGCTIGEFFRDNGMHCLVVYDDLSKHAVAYRQMSLLLRRPPGREAYPGDIFYVHSRLLERAAKMSDEKGQ
GSLTALPIIETQAGDVSAYVPTNVISITDGQIFLESELFHKGFRPAVNIGLSVSRVGSAAQLKSVKKVAGSIKLSLAQYR
ELEDFAKFGSDLDATVQLSLNKGKYLIELLKQKQYSPMQIEEQVLLMYIFSNLYGQLNKVQVSNINRFECDLINYFQTVH
PGVLKKLSGDMNDDIKDDILGIVSDFVTQFNCV

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=507, Percent_Identity=59.3688362919132, Blast_Score=623, Evalue=1e-178,
Organism=Homo sapiens, GI4757810, Length=507, Percent_Identity=59.3688362919132, Blast_Score=623, Evalue=1e-178,
Organism=Homo sapiens, GI19913428, Length=294, Percent_Identity=29.2517006802721, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI19913426, Length=295, Percent_Identity=28.135593220339, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI32189394, Length=400, Percent_Identity=26.25, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI19913424, Length=326, Percent_Identity=25.7668711656442, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1790172, Length=515, Percent_Identity=52.8155339805825, Blast_Score=535, Evalue=1e-153,
Organism=Escherichia coli, GI1790170, Length=418, Percent_Identity=25.5980861244019, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1788251, Length=343, Percent_Identity=27.4052478134111, Blast_Score=102, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=507, Percent_Identity=59.1715976331361, Blast_Score=617, Evalue=1e-177,
Organism=Caenorhabditis elegans, GI71988080, Length=507, Percent_Identity=59.1715976331361, Blast_Score=615, Evalue=1e-176,
Organism=Caenorhabditis elegans, GI71988074, Length=507, Percent_Identity=55.2268244575937, Blast_Score=560, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI17570191, Length=357, Percent_Identity=26.890756302521, Blast_Score=132, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17510931, Length=458, Percent_Identity=25.764192139738, Blast_Score=131, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI25144756, Length=366, Percent_Identity=26.2295081967213, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=64, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565854, Length=258, Percent_Identity=23.2558139534884, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71988068, Length=77, Percent_Identity=41.5584415584416, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319370, Length=505, Percent_Identity=56.8316831683168, Blast_Score=607, Evalue=1e-174,
Organism=Saccharomyces cerevisiae, GI6319603, Length=388, Percent_Identity=28.8659793814433, Blast_Score=136, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6322581, Length=403, Percent_Identity=25.8064516129032, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24658560, Length=508, Percent_Identity=58.6614173228346, Blast_Score=617, Evalue=1e-177,
Organism=Drosophila melanogaster, GI281361666, Length=344, Percent_Identity=28.1976744186047, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24646341, Length=344, Percent_Identity=28.1976744186047, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI17136796, Length=344, Percent_Identity=28.1976744186047, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28574560, Length=396, Percent_Identity=26.7676767676768, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24638766, Length=400, Percent_Identity=25.25, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24583992, Length=326, Percent_Identity=24.8466257668712, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583988, Length=255, Percent_Identity=26.2745098039216, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24583986, Length=255, Percent_Identity=26.2745098039216, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24583984, Length=255, Percent_Identity=26.2745098039216, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20129479, Length=253, Percent_Identity=28.0632411067194, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 56422; Mature: 56422

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNSINASEVVNIIKEKVETFDNPIKRENIGEVISVTDGITLVYGLEKAKFGEKVSFASG
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEEECHHHHCCCCCCCCCC
VEGIVLDLDHDTAGIVVLGNDRDVKEGDVVKCSGDVVQVPVGHELLGRVVNALGDPIDDG
CCEEEEEECCCCCEEEEECCCCCCCCCCEEEECCCEEEECCCHHHHHHHHHHHCCCCCCC
GEIRAKNKMYIESKAPGIIDRKSVHEPLQTGIKIIDLLIPIGRGQRELIIGDRQIGKTTI
CCEEECCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEE
AIDTIINQKKINDEVNENQKIYCVYVAIGQKISTVAKVVNKLKESGALEYTTVVVASASD
EEHHHHHHHHCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEEEECCCC
CAPMQFLAPYTGCTIGEFFRDNGMHCLVVYDDLSKHAVAYRQMSLLLRRPPGREAYPGDI
CCCHHHHCCCCCCCHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCH
FYVHSRLLERAAKMSDEKGQGSLTALPIIETQAGDVSAYVPTNVISITDGQIFLESELFH
HHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEEHHHHH
KGFRPAVNIGLSVSRVGSAAQLKSVKKVAGSIKLSLAQYRELEDFAKFGSDLDATVQLSL
CCCCCHHHCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
NKGKYLIELLKQKQYSPMQIEEQVLLMYIFSNLYGQLNKVQVSNINRFECDLINYFQTVH
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHC
PGVLKKLSGDMNDDIKDDILGIVSDFVTQFNCV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNSINASEVVNIIKEKVETFDNPIKRENIGEVISVTDGITLVYGLEKAKFGEKVSFASG
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEEECHHHHCCCCCCCCCC
VEGIVLDLDHDTAGIVVLGNDRDVKEGDVVKCSGDVVQVPVGHELLGRVVNALGDPIDDG
CCEEEEEECCCCCEEEEECCCCCCCCCCEEEECCCEEEECCCHHHHHHHHHHHCCCCCCC
GEIRAKNKMYIESKAPGIIDRKSVHEPLQTGIKIIDLLIPIGRGQRELIIGDRQIGKTTI
CCEEECCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEE
AIDTIINQKKINDEVNENQKIYCVYVAIGQKISTVAKVVNKLKESGALEYTTVVVASASD
EEHHHHHHHHCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEEEECCCC
CAPMQFLAPYTGCTIGEFFRDNGMHCLVVYDDLSKHAVAYRQMSLLLRRPPGREAYPGDI
CCCHHHHCCCCCCCHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCH
FYVHSRLLERAAKMSDEKGQGSLTALPIIETQAGDVSAYVPTNVISITDGQIFLESELFH
HHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEEHHHHH
KGFRPAVNIGLSVSRVGSAAQLKSVKKVAGSIKLSLAQYRELEDFAKFGSDLDATVQLSL
CCCCCHHHCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
NKGKYLIELLKQKQYSPMQIEEQVLLMYIFSNLYGQLNKVQVSNINRFECDLINYFQTVH
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHC
PGVLKKLSGDMNDDIKDDILGIVSDFVTQFNCV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA