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The map label for this gene is glmU [H]

Identifier: 190571517

GI number: 190571517

Start: 1221449

End: 1222675

Strand: Direct

Name: glmU [H]

Synonym: WPa_1136

Alternate gene names: 190571517

Gene position: 1221449-1222675 (Clockwise)

Preceding gene: 190571516

Following gene: 190571518

Centisome position: 82.39

GC content: 36.51

Gene sequence:

>1227_bases
GTGACAAATAAATCTTATACATTTGTTGTACTTGCTGCTGGGCATAGTGAACGAATGAATTCAAGCTTGCCTAAGGTTCT
GCACAAAATAGGTAATTTCTCCATGCTTGAGCATGTCATTTACAATGCAAAGCAGCTGAATCCTGAAAAAATAGTTATTG
TAGTCGATTTGCCTTTAACTCAAAGGCTGAAATGCTTTGAGGGTATAAAACTAATTACACAAGAGTCAACGCTCGGCACG
GGAGATGCAGTCAAAATTGCAATGAGGAACCTGAAAGAATTGTCAGATATAGTTGTTGTGCAGTATGGGGATACTCCACT
AATAAAAAGCAGCACAATAACTAAAATGATAAGCTGCTTAGGAGAGAGCAATGCTTTAGTTTGTCTTGGGTTTAAAACTA
ATAATAAAGGATACGGTAGACTAATTATTGAGAACGGTTCCCTAAGAGAAATCGTAGAAGCACAAAATGGTAGAAATAAT
GATTTTGCTAATGCCGGAATAATGGTTGCACGTGAAAAGAATCTACGTGAATTGGTGGAGAAAATAGAGTGTAATAACCA
AGCTCATGAATATTACTTGACCGATATCGTTTCCATTGCAGTAAAGAGTAATTTAAATGTCGGCTATGTTATTGCTGATG
AGGAGGAGGCAACTGGCATAAATAATAGGAATGACCTTGCAACGGCCGAGTTTTACTTTCAAGAAGAAAAAAGAAAGTTT
TTCACTAACTCTGGAGTAACACTTGTTGCTCCAGAAACTGTTTTCTTCTCTCTTGATACGCAAATTGGTATGGATTCGAT
TGTTTACCCATACGTTTTTTTTGGTCCTGGAGTAAAAATAGGATCTGGTGTTAGGGTTGGTCCATTTGCCAAATGTGAAA
ATACAACAATAGGTGATGGTGCAATCATAGGTAATTTTGTTGAAACAAAAGCAAGTGATATAGGTATAAATACTAAGATA
AAGCACTTAAGTTATATAGGAAATACTCAGGTAGGGCAGGGGAGTAACATAGGTGCAGGTACCGTTATTTGTAATTATGA
TGGGAAAAAGAAACATAAAACAAATATTGGAAGCAATTGTTTTATTGGTGCCAATAGCTCACTCATTGCACCGCTTAATG
TTCATGATGACTCTCTAGTTGCAGCAGGTAGCGTTATAGTAGAGGATGTGCCAGAGAAAAGTCTTGCAATTGCAAGAGAA
AGGCAAATAACTAAGAAAATAAAATAA

Upstream 100 bases:

>100_bases
AGCAATGCTGAAATATCAAATTAGTGATCTAAGGAGCTTTTACGACAATAGAGTTAGTTGGCTCAACCATTATGGTTTTC
ATTTTTCGTCTTTAAGATAA

Downstream 100 bases:

>100_bases
TTCCAATTTTTTTCTTGATGGTTATGCTTATATATGCATATGCTGAGATCTTAGATAAAAATGAAAAAATTATTTACCTT
GTTGGTTTGTTGTTCTCTTT

Product: bifunctional udp-n-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate n-acetyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MTNKSYTFVVLAAGHSERMNSSLPKVLHKIGNFSMLEHVIYNAKQLNPEKIVIVVDLPLTQRLKCFEGIKLITQESTLGT
GDAVKIAMRNLKELSDIVVVQYGDTPLIKSSTITKMISCLGESNALVCLGFKTNNKGYGRLIIENGSLREIVEAQNGRNN
DFANAGIMVAREKNLRELVEKIECNNQAHEYYLTDIVSIAVKSNLNVGYVIADEEEATGINNRNDLATAEFYFQEEKRKF
FTNSGVTLVAPETVFFSLDTQIGMDSIVYPYVFFGPGVKIGSGVRVGPFAKCENTTIGDGAIIGNFVETKASDIGINTKI
KHLSYIGNTQVGQGSNIGAGTVICNYDGKKKHKTNIGSNCFIGANSSLIAPLNVHDDSLVAAGSVIVEDVPEKSLAIARE
RQITKKIK

Sequences:

>Translated_408_residues
MTNKSYTFVVLAAGHSERMNSSLPKVLHKIGNFSMLEHVIYNAKQLNPEKIVIVVDLPLTQRLKCFEGIKLITQESTLGT
GDAVKIAMRNLKELSDIVVVQYGDTPLIKSSTITKMISCLGESNALVCLGFKTNNKGYGRLIIENGSLREIVEAQNGRNN
DFANAGIMVAREKNLRELVEKIECNNQAHEYYLTDIVSIAVKSNLNVGYVIADEEEATGINNRNDLATAEFYFQEEKRKF
FTNSGVTLVAPETVFFSLDTQIGMDSIVYPYVFFGPGVKIGSGVRVGPFAKCENTTIGDGAIIGNFVETKASDIGINTKI
KHLSYIGNTQVGQGSNIGAGTVICNYDGKKKHKTNIGSNCFIGANSSLIAPLNVHDDSLVAAGSVIVEDVPEKSLAIARE
RQITKKIK
>Mature_407_residues
TNKSYTFVVLAAGHSERMNSSLPKVLHKIGNFSMLEHVIYNAKQLNPEKIVIVVDLPLTQRLKCFEGIKLITQESTLGTG
DAVKIAMRNLKELSDIVVVQYGDTPLIKSSTITKMISCLGESNALVCLGFKTNNKGYGRLIIENGSLREIVEAQNGRNND
FANAGIMVAREKNLRELVEKIECNNQAHEYYLTDIVSIAVKSNLNVGYVIADEEEATGINNRNDLATAEFYFQEEKRKFF
TNSGVTLVAPETVFFSLDTQIGMDSIVYPYVFFGPGVKIGSGVRVGPFAKCENTTIGDGAIIGNFVETKASDIGINTKIK
HLSYIGNTQVGQGSNIGAGTVICNYDGKKKHKTNIGSNCFIGANSSLIAPLNVHDDSLVAAGSVIVEDVPEKSLAIARER
QITKKIK

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=451, Percent_Identity=33.0376940133038, Blast_Score=218, Evalue=6e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR001228
- InterPro:   IPR011004 [H]

Pfam domain/function: PF01128 IspD [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 44482; Mature: 44350

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNKSYTFVVLAAGHSERMNSSLPKVLHKIGNFSMLEHVIYNAKQLNPEKIVIVVDLPLT
CCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEEECCHH
QRLKCFEGIKLITQESTLGTGDAVKIAMRNLKELSDIVVVQYGDTPLIKSSTITKMISCL
HHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHH
GESNALVCLGFKTNNKGYGRLIIENGSLREIVEAQNGRNNDFANAGIMVAREKNLRELVE
CCCCCEEEEEEEECCCCCEEEEEECCCHHHHHHHCCCCCCCCCCCCEEEEECHHHHHHHH
KIECNNQAHEYYLTDIVSIAVKSNLNVGYVIADEEEATGINNRNDLATAEFYFQEEKRKF
HHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCHHHCCCCCCCCCEEHHHHHHHHHHHH
FTNSGVTLVAPETVFFSLDTQIGMDSIVYPYVFFGPGVKIGSGVRVGPFAKCENTTIGDG
HCCCCEEEEECCEEEEEECCCCCCCHHCCCEEEECCCEEECCCCEECCCCCCCCCCCCCC
AIIGNFVETKASDIGINTKIKHLSYIGNTQVGQGSNIGAGTVICNYDGKKKHKTNIGSNC
CEECCHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEE
FIGANSSLIAPLNVHDDSLVAAGSVIVEDVPEKSLAIARERQITKKIK
EEECCCCEEEEEECCCCCEEECCCEEEECCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNKSYTFVVLAAGHSERMNSSLPKVLHKIGNFSMLEHVIYNAKQLNPEKIVIVVDLPLT
CCCCEEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEEECCHH
QRLKCFEGIKLITQESTLGTGDAVKIAMRNLKELSDIVVVQYGDTPLIKSSTITKMISCL
HHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHH
GESNALVCLGFKTNNKGYGRLIIENGSLREIVEAQNGRNNDFANAGIMVAREKNLRELVE
CCCCCEEEEEEEECCCCCEEEEEECCCHHHHHHHCCCCCCCCCCCCEEEEECHHHHHHHH
KIECNNQAHEYYLTDIVSIAVKSNLNVGYVIADEEEATGINNRNDLATAEFYFQEEKRKF
HHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCHHHCCCCCCCCCEEHHHHHHHHHHHH
FTNSGVTLVAPETVFFSLDTQIGMDSIVYPYVFFGPGVKIGSGVRVGPFAKCENTTIGDG
HCCCCEEEEECCEEEEEECCCCCCCHHCCCEEEECCCEEECCCCEECCCCCCCCCCCCCC
AIIGNFVETKASDIGINTKIKHLSYIGNTQVGQGSNIGAGTVICNYDGKKKHKTNIGSNC
CEECCHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEE
FIGANSSLIAPLNVHDDSLVAAGSVIVEDVPEKSLAIARERQITKKIK
EEECCCCEEEEEECCCCCEEECCCEEEECCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA