| Definition | Wolbachia endosymbiont of Culex quinquefasciatus Pel, complete genome. |
|---|---|
| Accession | NC_010981 |
| Length | 1,482,455 |
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The map label for this gene is polA [H]
Identifier: 190571485
GI number: 190571485
Start: 1175516
End: 1178044
Strand: Reverse
Name: polA [H]
Synonym: WPa_1101
Alternate gene names: 190571485
Gene position: 1178044-1175516 (Counterclockwise)
Preceding gene: 190571486
Following gene: 190571484
Centisome position: 79.47
GC content: 33.73
Gene sequence:
>2529_bases ATGAAAGAAAAAACTTTCACAATCATTGATGGTTATGGTTTTCTTTTCAGAGCTTATTACGTTTTGCATCATTTGACTAC CACAGCTGGTATTCCAGTAGGTGCTGTGTACGGTTTTCTTAATATGGTTCTGAAGTATATTTCCCATTCGGACTACTTAA CTATAGCACTTGATTCTGGCAAAAAAAATTTCAGGCACAGTTTATATTCTGAGTATAAAGCAAACAGAGTAACACCTCCT GAGGATCTAATTCCACAATTTACAATACTGAGAGAAGCGGTAGAAGCTTTTAACTTCAGCTATGAAGAGATTGAAGGCTA TGAAGCAGATGACATAATTGCAACACTAGCTGCAAAATATGCCAACCACGAAGACTTTAAAGTAGTAGTAGTCTCATCAG ATAAAGACTTATTTCAACTTTTGAATTACAACATTCTAATATTTGATCCTATCAAAAATATATACGTAGATGAAAAACAA GTGATAGAAAAATTTGGTGTAAATTCAAATAAGCTTCTTGATTTATTTTCTCTAACTGGAGATGCATCTGATAACATTCC AGGTGTTCCAGGAATAGGCCCAAAAACTGCAGCTAAATTGCTGGATAAATTTGATTCGTTGGATAACATTATAGAAAACA TCAATAACATTGAGCAAACAAGAGTTCGTAATATTCTTACTGAGCATAAGGAAAAAGCACTAATTTCAAGAGAACTTTTG TCACTATGCAAAAAAGTAGATCTTCAACATGATATTGTAAAATATGAAGTTCATCCTCCAAATATGGAAAAATTGTTATC CTTTTTGAAGAAATATGAATTTAATTCATTGATAGGAAAAGTAGAAAAGCTCTTTTCTTATAGTGGATCTAGCACAAAAG AGAAAACAGAATATAGTAGTGAAGAATTAGAAAAATTTTTGGAGCATTGCAGATATGAAGGTAAAATTGCAATTCATTGC CACTTTGAAAACAATAGATTGAACAAAATCTCCTTATCTTGTAGTGAGGATAATATTTTCTACATAGATCAAAGCTGCCT ACAAGATGCACTTACTATAATAAATTCAACTTTATTTTCAAATGGGGTGCTTAAAATAGTACATGATATTAGAAAGATCA GAGAAATATTTCCTACAATAGAGAGAGTGCTAGACTCAATTGATGACCTGATGATCATGTCATACAGCCTTGACACAGGT AAGCATGATCACAGCATTCCAAACATAATTGCACACAATTTAAGTAAAAATGTAGAAACTTTCTCGGCAAAAATTTTAAT AGCGATCCATGAGAAACTGACACAAAGATTATTTCAGGAAAAACTTTTTACGATTTACGAGCGCTTTGATAGACCTCTCA TGAAAGTAATATTTGATATGGAGCAAAATGGAATACTGCTCAATATTCAAAAACTACAGGAATTGTCTGATAAGTTTGAG CAGCTAATTGCTGTACTTGAAAACGATATACATAATTTAGCAGGAGAAAAATTCAACATTGCATCGCCAAAACAATTAAG TGATGTTTTGTTTAATAAAATGGAGCTAAGTAAAAAGAAAAAGTCAAAATCTGGGTCGTATAGCACCAATTATGAAGTTC TAGAGGCTCTTGAAGAAGAAGGGGTAGAAATTGCAAGTAAAATTTTAAATTGGCGACATTTAAGTAAATTAAAGGGTACC TACACTGATGCGCTAATAAAGCAAGTTGATCCTATTGATGGTAGAATACACACAAGTTTCTCAACAACTGTGACTGCAAC TGGAAGGCTGAGCTCGAGCAACCCTAACTTGCAGAATATTCCTATCAGGAGCGAAGAAGGAAATTTCATCAGACAAGCAT TTATTGCACCAAAAGGTTGCAAGATAATTTCTGCCGACTATTCACAAATAGAATTAAAACTCCTGGCACACGTTGCAAAT GTTACCGCATTTAAAGAAGCTTTTGCAAACAGGCAAGATATTCATGATATCACTGCAAGACAAGTTTTTGGAGTGCAAGA AATAGATGAGCAATTAAGACGCAAAGCAAAAACCATTAATTTTGGCATTATATATGGCATTAGTCCATTTGGCCTTGCAA AGCGACTTGGCATTACCTTTCAAGAGGCTGCTGAATACATTAATTACTATTTTTCTTGTTACCCAGAAATAAAGGTCTAT ATGGAAAAAGCAGTATCTATCGCGAGAAATCATGGTTATGTAGAGACTTTGTTTGGTAGAAGATGTTTTGTAAGAGACAT CAACAATAAAATTCCTTATCTAAGACAATTTGCAGAAAGGGCAGCAATAAATGCACCACTGCAGGGAACTGCCGCTGATA TAATAAAACGCGCGATGATTCGGCTTTTTGATCAGTTAAAGTCAGGTAAAATAATCCTCCAGGTTCATGATGAATTACTT GTAGAAGTGGAAGAGAGCAGAGTGCAAGAAACAGCAAAACTTATGAAAGATATAATGGAAAATGCAGTAGAAATTTCTAT ACCACTTGAAGTAGAAATAAAAATTAGCGACAACTGGGGCTTTTCTTAA
Upstream 100 bases:
>100_bases ATAGTAACTATAGCATTATGATTATTTTGGCTATAGGAAACAAGAGCTTGATTTTTACAGCTAAATAACAGACCATCAAA GGCACACATAAATATCTACA
Downstream 100 bases:
>100_bases TTATACCGTAGACCCTAAGAACCTGTCTTGAAAGGACTTAAGTAGTATCTGTTCAGATGCATGGCTAATGTGTAAATATT GAAGCAAAAGTAATGTCATC
Product: DNA polymerase I
Products: NA
Alternate protein names: POL I [H]
Number of amino acids: Translated: 842; Mature: 842
Protein sequence:
>842_residues MKEKTFTIIDGYGFLFRAYYVLHHLTTTAGIPVGAVYGFLNMVLKYISHSDYLTIALDSGKKNFRHSLYSEYKANRVTPP EDLIPQFTILREAVEAFNFSYEEIEGYEADDIIATLAAKYANHEDFKVVVVSSDKDLFQLLNYNILIFDPIKNIYVDEKQ VIEKFGVNSNKLLDLFSLTGDASDNIPGVPGIGPKTAAKLLDKFDSLDNIIENINNIEQTRVRNILTEHKEKALISRELL SLCKKVDLQHDIVKYEVHPPNMEKLLSFLKKYEFNSLIGKVEKLFSYSGSSTKEKTEYSSEELEKFLEHCRYEGKIAIHC HFENNRLNKISLSCSEDNIFYIDQSCLQDALTIINSTLFSNGVLKIVHDIRKIREIFPTIERVLDSIDDLMIMSYSLDTG KHDHSIPNIIAHNLSKNVETFSAKILIAIHEKLTQRLFQEKLFTIYERFDRPLMKVIFDMEQNGILLNIQKLQELSDKFE QLIAVLENDIHNLAGEKFNIASPKQLSDVLFNKMELSKKKKSKSGSYSTNYEVLEALEEEGVEIASKILNWRHLSKLKGT YTDALIKQVDPIDGRIHTSFSTTVTATGRLSSSNPNLQNIPIRSEEGNFIRQAFIAPKGCKIISADYSQIELKLLAHVAN VTAFKEAFANRQDIHDITARQVFGVQEIDEQLRRKAKTINFGIIYGISPFGLAKRLGITFQEAAEYINYYFSCYPEIKVY MEKAVSIARNHGYVETLFGRRCFVRDINNKIPYLRQFAERAAINAPLQGTAADIIKRAMIRLFDQLKSGKIILQVHDELL VEVEESRVQETAKLMKDIMENAVEISIPLEVEIKISDNWGFS
Sequences:
>Translated_842_residues MKEKTFTIIDGYGFLFRAYYVLHHLTTTAGIPVGAVYGFLNMVLKYISHSDYLTIALDSGKKNFRHSLYSEYKANRVTPP EDLIPQFTILREAVEAFNFSYEEIEGYEADDIIATLAAKYANHEDFKVVVVSSDKDLFQLLNYNILIFDPIKNIYVDEKQ VIEKFGVNSNKLLDLFSLTGDASDNIPGVPGIGPKTAAKLLDKFDSLDNIIENINNIEQTRVRNILTEHKEKALISRELL SLCKKVDLQHDIVKYEVHPPNMEKLLSFLKKYEFNSLIGKVEKLFSYSGSSTKEKTEYSSEELEKFLEHCRYEGKIAIHC HFENNRLNKISLSCSEDNIFYIDQSCLQDALTIINSTLFSNGVLKIVHDIRKIREIFPTIERVLDSIDDLMIMSYSLDTG KHDHSIPNIIAHNLSKNVETFSAKILIAIHEKLTQRLFQEKLFTIYERFDRPLMKVIFDMEQNGILLNIQKLQELSDKFE QLIAVLENDIHNLAGEKFNIASPKQLSDVLFNKMELSKKKKSKSGSYSTNYEVLEALEEEGVEIASKILNWRHLSKLKGT YTDALIKQVDPIDGRIHTSFSTTVTATGRLSSSNPNLQNIPIRSEEGNFIRQAFIAPKGCKIISADYSQIELKLLAHVAN VTAFKEAFANRQDIHDITARQVFGVQEIDEQLRRKAKTINFGIIYGISPFGLAKRLGITFQEAAEYINYYFSCYPEIKVY MEKAVSIARNHGYVETLFGRRCFVRDINNKIPYLRQFAERAAINAPLQGTAADIIKRAMIRLFDQLKSGKIILQVHDELL VEVEESRVQETAKLMKDIMENAVEISIPLEVEIKISDNWGFS >Mature_842_residues MKEKTFTIIDGYGFLFRAYYVLHHLTTTAGIPVGAVYGFLNMVLKYISHSDYLTIALDSGKKNFRHSLYSEYKANRVTPP EDLIPQFTILREAVEAFNFSYEEIEGYEADDIIATLAAKYANHEDFKVVVVSSDKDLFQLLNYNILIFDPIKNIYVDEKQ VIEKFGVNSNKLLDLFSLTGDASDNIPGVPGIGPKTAAKLLDKFDSLDNIIENINNIEQTRVRNILTEHKEKALISRELL SLCKKVDLQHDIVKYEVHPPNMEKLLSFLKKYEFNSLIGKVEKLFSYSGSSTKEKTEYSSEELEKFLEHCRYEGKIAIHC HFENNRLNKISLSCSEDNIFYIDQSCLQDALTIINSTLFSNGVLKIVHDIRKIREIFPTIERVLDSIDDLMIMSYSLDTG KHDHSIPNIIAHNLSKNVETFSAKILIAIHEKLTQRLFQEKLFTIYERFDRPLMKVIFDMEQNGILLNIQKLQELSDKFE QLIAVLENDIHNLAGEKFNIASPKQLSDVLFNKMELSKKKKSKSGSYSTNYEVLEALEEEGVEIASKILNWRHLSKLKGT YTDALIKQVDPIDGRIHTSFSTTVTATGRLSSSNPNLQNIPIRSEEGNFIRQAFIAPKGCKIISADYSQIELKLLAHVAN VTAFKEAFANRQDIHDITARQVFGVQEIDEQLRRKAKTINFGIIYGISPFGLAKRLGITFQEAAEYINYYFSCYPEIKVY MEKAVSIARNHGYVETLFGRRCFVRDINNKIPYLRQFAERAAINAPLQGTAADIIKRAMIRLFDQLKSGKIILQVHDELL VEVEESRVQETAKLMKDIMENAVEISIPLEVEIKISDNWGFS
Specific function: In addition to polymerase activity, this DNA polymerase 5' to 3' exonuclease activity [H]
COG id: COG0749
COG function: function code L; DNA polymerase I - 3'-5' exonuclease and polymerase domains
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 5'-3' exonuclease domain [H]
Homologues:
Organism=Homo sapiens, GI112420958, Length=471, Percent_Identity=29.5116772823779, Blast_Score=201, Evalue=2e-51, Organism=Homo sapiens, GI139394648, Length=527, Percent_Identity=26.3757115749526, Blast_Score=161, Evalue=3e-39, Organism=Escherichia coli, GI1790294, Length=925, Percent_Identity=35.7837837837838, Blast_Score=514, Evalue=1e-147, Organism=Escherichia coli, GI226510970, Length=188, Percent_Identity=36.7021276595745, Blast_Score=112, Evalue=1e-25, Organism=Caenorhabditis elegans, GI86563272, Length=397, Percent_Identity=29.9748110831234, Blast_Score=159, Evalue=4e-39, Organism=Drosophila melanogaster, GI17933644, Length=532, Percent_Identity=27.8195488721804, Blast_Score=199, Evalue=7e-51,
Paralogues:
None
Copy number: 400 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR020046 - InterPro: IPR020045 - InterPro: IPR002421 - InterPro: IPR020047 - InterPro: IPR019760 - InterPro: IPR001098 - InterPro: IPR018320 - InterPro: IPR002298 - InterPro: IPR008918 - InterPro: IPR012337 [H]
Pfam domain/function: PF01367 5_3_exonuc; PF02739 5_3_exonuc_N; PF00476 DNA_pol_A [H]
EC number: =2.7.7.7 [H]
Molecular weight: Translated: 96264; Mature: 96264
Theoretical pI: Translated: 6.49; Mature: 6.49
Prosite motif: PS00447 DNA_POLYMERASE_A
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.0 %Cys (Translated Protein) 1.4 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 1.0 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKEKTFTIIDGYGFLFRAYYVLHHLTTTAGIPVGAVYGFLNMVLKYISHSDYLTIALDSG CCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCC KKNFRHSLYSEYKANRVTPPEDLIPQFTILREAVEAFNFSYEEIEGYEADDIIATLAAKY CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHH ANHEDFKVVVVSSDKDLFQLLNYNILIFDPIKNIYVDEKQVIEKFGVNSNKLLDLFSLTG CCCCCEEEEEEECCHHHHHHHCCCEEEECCHHHHCCCHHHHHHHHCCCCCHHHHHHHHCC DASDNIPGVPGIGPKTAAKLLDKFDSLDNIIENINNIEQTRVRNILTEHKEKALISRELL CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH SLCKKVDLQHDIVKYEVHPPNMEKLLSFLKKYEFNSLIGKVEKLFSYSGSSTKEKTEYSS HHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCH EELEKFLEHCRYEGKIAIHCHFENNRLNKISLSCSEDNIFYIDQSCLQDALTIINSTLFS HHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEEECCCCEEEECHHHHHHHHHHHHHHHHC NGVLKIVHDIRKIREIFPTIERVLDSIDDLMIMSYSLDTGKHDHSIPNIIAHNLSKNVET CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHCCHHH FSAKILIAIHEKLTQRLFQEKLFTIYERFDRPLMKVIFDMEQNGILLNIQKLQELSDKFE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHH QLIAVLENDIHNLAGEKFNIASPKQLSDVLFNKMELSKKKKSKSGSYSTNYEVLEALEEE HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHC GVEIASKILNWRHLSKLKGTYTDALIKQVDPIDGRIHTSFSTTVTATGRLSSSNPNLQNI CHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEECCCEEEEEECEECCCCCCCCCC PIRSEEGNFIRQAFIAPKGCKIISADYSQIELKLLAHVANVTAFKEAFANRQDIHDITAR CCCCCCCCHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH QVFGVQEIDEQLRRKAKTINFGIIYGISPFGLAKRLGITFQEAAEYINYYFSCYPEIKVY HHHCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH MEKAVSIARNHGYVETLFGRRCFVRDINNKIPYLRQFAERAAINAPLQGTAADIIKRAMI HHHHHHHHHCCCHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHH RLFDQLKSGKIILQVHDELLVEVEESRVQETAKLMKDIMENAVEISIPLEVEIKISDNWG HHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEEECCCCC FS CC >Mature Secondary Structure MKEKTFTIIDGYGFLFRAYYVLHHLTTTAGIPVGAVYGFLNMVLKYISHSDYLTIALDSG CCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCC KKNFRHSLYSEYKANRVTPPEDLIPQFTILREAVEAFNFSYEEIEGYEADDIIATLAAKY CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHH ANHEDFKVVVVSSDKDLFQLLNYNILIFDPIKNIYVDEKQVIEKFGVNSNKLLDLFSLTG CCCCCEEEEEEECCHHHHHHHCCCEEEECCHHHHCCCHHHHHHHHCCCCCHHHHHHHHCC DASDNIPGVPGIGPKTAAKLLDKFDSLDNIIENINNIEQTRVRNILTEHKEKALISRELL CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH SLCKKVDLQHDIVKYEVHPPNMEKLLSFLKKYEFNSLIGKVEKLFSYSGSSTKEKTEYSS HHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCH EELEKFLEHCRYEGKIAIHCHFENNRLNKISLSCSEDNIFYIDQSCLQDALTIINSTLFS HHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEEECCCCEEEECHHHHHHHHHHHHHHHHC NGVLKIVHDIRKIREIFPTIERVLDSIDDLMIMSYSLDTGKHDHSIPNIIAHNLSKNVET CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHCCHHH FSAKILIAIHEKLTQRLFQEKLFTIYERFDRPLMKVIFDMEQNGILLNIQKLQELSDKFE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHH QLIAVLENDIHNLAGEKFNIASPKQLSDVLFNKMELSKKKKSKSGSYSTNYEVLEALEEE HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHC GVEIASKILNWRHLSKLKGTYTDALIKQVDPIDGRIHTSFSTTVTATGRLSSSNPNLQNI CHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEECCCEEEEEECEECCCCCCCCCC PIRSEEGNFIRQAFIAPKGCKIISADYSQIELKLLAHVANVTAFKEAFANRQDIHDITAR CCCCCCCCHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH QVFGVQEIDEQLRRKAKTINFGIIYGISPFGLAKRLGITFQEAAEYINYYFSCYPEIKVY HHHCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH MEKAVSIARNHGYVETLFGRRCFVRDINNKIPYLRQFAERAAINAPLQGTAADIIKRAMI HHHHHHHHHCCCHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHH RLFDQLKSGKIILQVHDELLVEVEESRVQETAKLMKDIMENAVEISIPLEVEIKISDNWG HHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEEECCCCC FS CC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA