Click here to switch to the map view.

The map label for this gene is ccmE [H]

Identifier: 190571392

GI number: 190571392

Start: 1067354

End: 1067746

Strand: Direct

Name: ccmE [H]

Synonym: WPa_1000

Alternate gene names: 190571392

Gene position: 1067354-1067746 (Clockwise)

Preceding gene: 190571391

Following gene: 190571396

Centisome position: 72.0

GC content: 33.08

Gene sequence:

>393_bases
ATGAAGAAGAAACATAAGCGATTACTTATAACTTCAGGAATTTTCTGCTTTTTAAGTTGTGCAGTTTTTTTTATTTTAAC
AACGCTCAAAGAAAATATCTCATTTTTCTATACAGTAAGTGAGGCAATAGTTTTACCAAATAATCAAAAGCCAATCCGTG
TTGGTGGAATGATTGTTGAAAATAGCGTGATACGGAGCGAAAGCGAAGTAATTTTTCAGATGACAGATTTTAATAAGAGC
GTTATGGTGAAATATCAGGGAATACTTCCACCAATGTTTTCAGAAAAAAGTGGTGTTGTTGTACAAGGTAAAATGTTTGA
TAATGGTACCTTTCTTGCAGATACGGTGTTTGCAAAACATGATGAGAACTATAAGCCGAAAGTCCTAAAATAG

Upstream 100 bases:

>100_bases
GCTTACCTTATTAGTTTCATACTGATTGGTGGAAATTTGATTTTTACCGTTTCTTGCTATACTAAAAGTAAAAAAATTCT
AGAAAGCCTGAAAGATAATA

Downstream 100 bases:

>100_bases
ATTTCCTAATTCAGTTGTATTGAAATGGTATGTGAAAGAAAGCAACAGCCTGCTAGCAAGCTGTTACTTTCCTAACTACC
ACAATATATCAGAGTGAGTT

Product: cytochrome c-type biogenesis protein CcmE

Products: NA

Alternate protein names: Cytochrome c maturation protein E; Heme chaperone CcmE [H]

Number of amino acids: Translated: 130; Mature: 130

Protein sequence:

>130_residues
MKKKHKRLLITSGIFCFLSCAVFFILTTLKENISFFYTVSEAIVLPNNQKPIRVGGMIVENSVIRSESEVIFQMTDFNKS
VMVKYQGILPPMFSEKSGVVVQGKMFDNGTFLADTVFAKHDENYKPKVLK

Sequences:

>Translated_130_residues
MKKKHKRLLITSGIFCFLSCAVFFILTTLKENISFFYTVSEAIVLPNNQKPIRVGGMIVENSVIRSESEVIFQMTDFNKS
VMVKYQGILPPMFSEKSGVVVQGKMFDNGTFLADTVFAKHDENYKPKVLK
>Mature_130_residues
MKKKHKRLLITSGIFCFLSCAVFFILTTLKENISFFYTVSEAIVLPNNQKPIRVGGMIVENSVIRSESEVIFQMTDFNKS
VMVKYQGILPPMFSEKSGVVVQGKMFDNGTFLADTVFAKHDENYKPKVLK

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH [H]

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family [H]

Homologues:

Organism=Escherichia coli, GI1788525, Length=133, Percent_Identity=38.3458646616541, Blast_Score=95, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004329
- InterPro:   IPR012340 [H]

Pfam domain/function: PF03100 CcmE [H]

EC number: NA

Molecular weight: Translated: 14766; Mature: 14766

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKHKRLLITSGIFCFLSCAVFFILTTLKENISFFYTVSEAIVLPNNQKPIRVGGMIVE
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEECCCCCCEEECCEEEE
NSVIRSESEVIFQMTDFNKSVMVKYQGILPPMFSEKSGVVVQGKMFDNGTFLADTVFAKH
CCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCEEEEEEEECCCCEEEEEEEECC
DENYKPKVLK
CCCCCCCCCC
>Mature Secondary Structure
MKKKHKRLLITSGIFCFLSCAVFFILTTLKENISFFYTVSEAIVLPNNQKPIRVGGMIVE
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEECCCCCCEEECCEEEE
NSVIRSESEVIFQMTDFNKSVMVKYQGILPPMFSEKSGVVVQGKMFDNGTFLADTVFAKH
CCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCEEEEEEEECCCCEEEEEEEECC
DENYKPKVLK
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA