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The map label for this gene is argD [H]

Identifier: 190571185

GI number: 190571185

Start: 858730

End: 859899

Strand: Reverse

Name: argD [H]

Synonym: WPa_0783

Alternate gene names: 190571185

Gene position: 859899-858730 (Counterclockwise)

Preceding gene: 190571192

Following gene: 190571183

Centisome position: 58.01

GC content: 35.81

Gene sequence:

>1170_bases
ATGACAATTTCTCCTATCTTGCCAGTTTATTCTCCTGTTAACATAAATTTTTCTTATGGCAAAGGTATTTACTTGTATGA
TATCGATAATAAGCGCTATATAGATTTTCACTCTGGAATAGCTGTTAGCAGTTTAGGTCATGCCAACCCACGATTAACTG
ATGTCCTAAAATTACAAGGAGAAAAACTATGGCATATATCAAATACCTATAATATATCTACTGCCAACAAATTTGCAGAA
AATTTAATAAACAACAGCTTTGCTAATACTGTATTTTTTGCAAATTCTGGATCAGAAGCAGTGGAATGTGGACTTAAAAT
CGCTAGGGCCTATCAAAATGGAAAAGGTAATAAAAATCGCTATAGAATTCTAACATTTCATGGTGCATTTCATGGAAGGA
CATTTTTAACTTGTGCAACAAACGATAGACAGAAATTTTCTGAATTACTGAATCCTTATATTGACTGGTGTGATAACATA
GAGCCCAATATTGAGAGTGTAAAGAAAGCAATTTCTAATGGCATAGGTGTTATATTAATAGAACCAATACAGGGACAAGG
TGGTATTAAAGTAATGAGTGAAGTCTTCATGAAAGAGCTAAGAGAACTATGTAACGAAAACGACATACTGCTATTTTTTG
ATTGCGTTCAGTGCGGTGCTGGCAGGACAGGAAAGTTATTTGCATATGAACACATAGGAATTAAGCCTGACATATGTGCT
CTTGCAAAAGGAATAGGAGGAGGTTTCCCTCTGGGGGCTTGTCTTGCAACTGAAAAGGTTGCTAAGTACATGGCGGTCGG
TATGCATGGTTCTACTTTTGGTGGTAATCCACTTGCAACTTCAGTAGGTAATGCTGTATTGGATGAATTGCTCAGCCCTG
GCTTCTTAGAAAATGTTGAAGTTAGAGGTAAGTACTTAAAAAACAAACTAGAAAATTTAGCAAGCAAGTTTCCAATGATA
GAAGAAGTGAGAGGAAAAGGGTTGATGCTAGGAATAAAAGTAAAAATGAATAACCAAAAATTTGCAGAAGAGCTAAGTCA
CCGTGGTTTACTCACTGTTGGAGTAACATCAGATAACGTTCTAAGAATCTTGCCTCCACTCATTATCACTGAAAAAGAGA
TTGATGAAGGCATTGAAATCCTCACTCAGTATTTATCTGAAAAGTTCTAG

Upstream 100 bases:

>100_bases
TAGTGTAGTAAAAATTAATTTACTTAATTTATACATATTCTTCTCATTGTGAAATAACGTCTTTTATGGTATTAATAAAA
AATTAGCATATCATACTTTT

Downstream 100 bases:

>100_bases
TTAAAAACTAAACCTTCCTGCTCACTAGTTGTTGGCTGTATCAAAATTGCAGATAAAGCAGTAGCTACAACTTTATCAGC
TACTTCATTTGTACACTTTG

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MTISPILPVYSPVNINFSYGKGIYLYDIDNKRYIDFHSGIAVSSLGHANPRLTDVLKLQGEKLWHISNTYNISTANKFAE
NLINNSFANTVFFANSGSEAVECGLKIARAYQNGKGNKNRYRILTFHGAFHGRTFLTCATNDRQKFSELLNPYIDWCDNI
EPNIESVKKAISNGIGVILIEPIQGQGGIKVMSEVFMKELRELCNENDILLFFDCVQCGAGRTGKLFAYEHIGIKPDICA
LAKGIGGGFPLGACLATEKVAKYMAVGMHGSTFGGNPLATSVGNAVLDELLSPGFLENVEVRGKYLKNKLENLASKFPMI
EEVRGKGLMLGIKVKMNNQKFAEELSHRGLLTVGVTSDNVLRILPPLIITEKEIDEGIEILTQYLSEKF

Sequences:

>Translated_389_residues
MTISPILPVYSPVNINFSYGKGIYLYDIDNKRYIDFHSGIAVSSLGHANPRLTDVLKLQGEKLWHISNTYNISTANKFAE
NLINNSFANTVFFANSGSEAVECGLKIARAYQNGKGNKNRYRILTFHGAFHGRTFLTCATNDRQKFSELLNPYIDWCDNI
EPNIESVKKAISNGIGVILIEPIQGQGGIKVMSEVFMKELRELCNENDILLFFDCVQCGAGRTGKLFAYEHIGIKPDICA
LAKGIGGGFPLGACLATEKVAKYMAVGMHGSTFGGNPLATSVGNAVLDELLSPGFLENVEVRGKYLKNKLENLASKFPMI
EEVRGKGLMLGIKVKMNNQKFAEELSHRGLLTVGVTSDNVLRILPPLIITEKEIDEGIEILTQYLSEKF
>Mature_388_residues
TISPILPVYSPVNINFSYGKGIYLYDIDNKRYIDFHSGIAVSSLGHANPRLTDVLKLQGEKLWHISNTYNISTANKFAEN
LINNSFANTVFFANSGSEAVECGLKIARAYQNGKGNKNRYRILTFHGAFHGRTFLTCATNDRQKFSELLNPYIDWCDNIE
PNIESVKKAISNGIGVILIEPIQGQGGIKVMSEVFMKELRELCNENDILLFFDCVQCGAGRTGKLFAYEHIGIKPDICAL
AKGIGGGFPLGACLATEKVAKYMAVGMHGSTFGGNPLATSVGNAVLDELLSPGFLENVEVRGKYLKNKLENLASKFPMIE
EVRGKGLMLGIKVKMNNQKFAEELSHRGLLTVGVTSDNVLRILPPLIITEKEIDEGIEILTQYLSEKF

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=383, Percent_Identity=31.8537859007833, Blast_Score=194, Evalue=9e-50,
Organism=Homo sapiens, GI13994255, Length=445, Percent_Identity=30.1123595505618, Blast_Score=188, Evalue=9e-48,
Organism=Homo sapiens, GI284507298, Length=300, Percent_Identity=32.6666666666667, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI37574042, Length=405, Percent_Identity=26.1728395061728, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI226442709, Length=334, Percent_Identity=27.5449101796407, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI226442705, Length=337, Percent_Identity=27.299703264095, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI24119277, Length=392, Percent_Identity=26.530612244898, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI188536080, Length=430, Percent_Identity=23.2558139534884, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI38679950, Length=430, Percent_Identity=23.2558139534884, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI38679946, Length=430, Percent_Identity=23.2558139534884, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1789759, Length=387, Percent_Identity=37.2093023255814, Blast_Score=294, Evalue=8e-81,
Organism=Escherichia coli, GI1788044, Length=378, Percent_Identity=39.1534391534392, Blast_Score=292, Evalue=3e-80,
Organism=Escherichia coli, GI1789016, Length=404, Percent_Identity=33.9108910891089, Blast_Score=201, Evalue=7e-53,
Organism=Escherichia coli, GI145693181, Length=378, Percent_Identity=31.4814814814815, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1787560, Length=401, Percent_Identity=32.6683291770574, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1786991, Length=354, Percent_Identity=31.9209039548023, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786349, Length=326, Percent_Identity=27.3006134969325, Blast_Score=99, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI25144271, Length=386, Percent_Identity=30.8290155440415, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI32564660, Length=446, Percent_Identity=29.5964125560538, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI25144274, Length=264, Percent_Identity=32.9545454545455, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI71992977, Length=418, Percent_Identity=27.0334928229665, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17541228, Length=306, Percent_Identity=23.8562091503268, Blast_Score=88, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6324432, Length=389, Percent_Identity=35.4755784061697, Blast_Score=232, Evalue=8e-62,
Organism=Saccharomyces cerevisiae, GI6323470, Length=401, Percent_Identity=31.4214463840399, Blast_Score=186, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6324386, Length=456, Percent_Identity=27.1929824561404, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6321456, Length=424, Percent_Identity=24.2924528301887, Blast_Score=96, Evalue=7e-21,
Organism=Drosophila melanogaster, GI21357415, Length=384, Percent_Identity=31.5104166666667, Blast_Score=194, Evalue=7e-50,
Organism=Drosophila melanogaster, GI28574759, Length=421, Percent_Identity=30.8788598574822, Blast_Score=177, Evalue=9e-45,
Organism=Drosophila melanogaster, GI161085790, Length=415, Percent_Identity=30.6024096385542, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI21356575, Length=426, Percent_Identity=26.7605633802817, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI281366494, Length=410, Percent_Identity=28.5365853658537, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24667139, Length=410, Percent_Identity=28.5365853658537, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24667143, Length=410, Percent_Identity=28.5365853658537, Blast_Score=109, Evalue=4e-24,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42900; Mature: 42769

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISPILPVYSPVNINFSYGKGIYLYDIDNKRYIDFHSGIAVSSLGHANPRLTDVLKLQG
CCCCCCCCCCCCEEEEEECCCEEEEEECCCCEEEEECCCEEEECCCCCCCCHHHHHHHCC
EKLWHISNTYNISTANKFAENLINNSFANTVFFANSGSEAVECGLKIARAYQNGKGNKNR
CEEEEECCCEEECHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCE
YRILTFHGAFHGRTFLTCATNDRQKFSELLNPYIDWCDNIEPNIESVKKAISNGIGVILI
EEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEE
EPIQGQGGIKVMSEVFMKELRELCNENDILLFFDCVQCGAGRTGKLFAYEHIGIKPDICA
EECCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHCCCCCCCEEEEECCCCCCHHHH
LAKGIGGGFPLGACLATEKVAKYMAVGMHGSTFGGNPLATSVGNAVLDELLSPGFLENVE
HHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHH
VRGKYLKNKLENLASKFPMIEEVRGKGLMLGIKVKMNNQKFAEELSHRGLLTVGVTSDNV
HHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEEEEEECCHHHHHHHHCCCEEEEECCCCCH
LRILPPLIITEKEIDEGIEILTQYLSEKF
HHHCCCCEEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TISPILPVYSPVNINFSYGKGIYLYDIDNKRYIDFHSGIAVSSLGHANPRLTDVLKLQG
CCCCCCCCCCCEEEEEECCCEEEEEECCCCEEEEECCCEEEECCCCCCCCHHHHHHHCC
EKLWHISNTYNISTANKFAENLINNSFANTVFFANSGSEAVECGLKIARAYQNGKGNKNR
CEEEEECCCEEECHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCE
YRILTFHGAFHGRTFLTCATNDRQKFSELLNPYIDWCDNIEPNIESVKKAISNGIGVILI
EEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEE
EPIQGQGGIKVMSEVFMKELRELCNENDILLFFDCVQCGAGRTGKLFAYEHIGIKPDICA
EECCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHCCCCCCCEEEEECCCCCCHHHH
LAKGIGGGFPLGACLATEKVAKYMAVGMHGSTFGGNPLATSVGNAVLDELLSPGFLENVE
HHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHH
VRGKYLKNKLENLASKFPMIEEVRGKGLMLGIKVKMNNQKFAEELSHRGLLTVGVTSDNV
HHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEEEEEECCHHHHHHHHCCCEEEEECCCCCH
LRILPPLIITEKEIDEGIEILTQYLSEKF
HHHCCCCEEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]