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The map label for this gene is polA [H]

Identifier: 190571105

GI number: 190571105

Start: 770915

End: 771535

Strand: Reverse

Name: polA [H]

Synonym: WPa_0703

Alternate gene names: 190571105

Gene position: 771535-770915 (Counterclockwise)

Preceding gene: 190571109

Following gene: 190571104

Centisome position: 52.04

GC content: 34.46

Gene sequence:

>621_bases
ATGAGAATATTTATATATAAGGACGACCTGCCAGCCAGTGCAATACCGAATGATATAAAATCTATAGCTGTTGATACAGA
GGCAATGGGGCTACTGCATAGCAGAGATAGATTATGCCTTGTTCAGCTCTCTTTCAATGATGGCAACGCTCACTTAGTTC
AATTCAAAAACGATTATACAGCTCCAAATTTGAGAAAAATATTAGAGGATAAAAATATAACCAAAATATTTCACTTTGCG
CGATTTGATGTGAGTATAATACATTACTACCTGCAAACTTGGGCACTGCCTTGCTATTGCACGAAAATAGCCTCACGTTT
AGTTCGCACCTACACAGATAATCATAGCTTAAAAGAGTTGTGCTTAGAACTACTTGATATAAAATTAAATAAGCAACAAC
AATCTTCTGATTGGGGAAATGAAAATTTAACAGACAAGCAAAAAAGTTATGCTGCATCTGATGTTTTATATCTCCATAAA
ATAAAGGAAAAGCTAGATTTAATGCTAGAACGTGAAAATAGAAAAGAATTAGCCGAAAAGTGCTTTGAATTTCTTCCTAC
TCGTATTGAGCTAGATTCAATGGGTTGGGGGAGTGTAGATATCTTTAATCATCATATGTAA

Upstream 100 bases:

>100_bases
CTACATGCATGAAAATCATGAGAGCCAATTTTCTATGATCTTTTCGTATACTTAAAACTCATTTTTGATTATTGTATGTG
TCATAAAACATATTAAATTT

Downstream 100 bases:

>100_bases
TCACTTCACTTGAATCCAGAAAAATTTAGTTGATCAGCTGTTAATTGATACGCTATATTTATAAAAATTTAGGTATTTTA
TGAGTGATGATATTAAAGCG

Product: 3'-5' exonuclease

Products: NA

Alternate protein names: POL I [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MRIFIYKDDLPASAIPNDIKSIAVDTEAMGLLHSRDRLCLVQLSFNDGNAHLVQFKNDYTAPNLRKILEDKNITKIFHFA
RFDVSIIHYYLQTWALPCYCTKIASRLVRTYTDNHSLKELCLELLDIKLNKQQQSSDWGNENLTDKQKSYAASDVLYLHK
IKEKLDLMLERENRKELAEKCFEFLPTRIELDSMGWGSVDIFNHHM

Sequences:

>Translated_206_residues
MRIFIYKDDLPASAIPNDIKSIAVDTEAMGLLHSRDRLCLVQLSFNDGNAHLVQFKNDYTAPNLRKILEDKNITKIFHFA
RFDVSIIHYYLQTWALPCYCTKIASRLVRTYTDNHSLKELCLELLDIKLNKQQQSSDWGNENLTDKQKSYAASDVLYLHK
IKEKLDLMLERENRKELAEKCFEFLPTRIELDSMGWGSVDIFNHHM
>Mature_206_residues
MRIFIYKDDLPASAIPNDIKSIAVDTEAMGLLHSRDRLCLVQLSFNDGNAHLVQFKNDYTAPNLRKILEDKNITKIFHFA
RFDVSIIHYYLQTWALPCYCTKIASRLVRTYTDNHSLKELCLELLDIKLNKQQQSSDWGNENLTDKQKSYAASDVLYLHK
IKEKLDLMLERENRKELAEKCFEFLPTRIELDSMGWGSVDIFNHHM

Specific function: Cleaves Multimeric tRNA Precursor At The Spacer Region. [C]

COG id: COG0349

COG function: function code J; Ribonuclease D

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 3'-5' exonuclease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR019760
- InterPro:   IPR001098
- InterPro:   IPR002298
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF00476 DNA_pol_A [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 24101; Mature: 24101

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIFIYKDDLPASAIPNDIKSIAVDTEAMGLLHSRDRLCLVQLSFNDGNAHLVQFKNDYT
CEEEEEECCCCCCCCCHHHHHHHCCHHHHHHHHCCCCEEEEEEEECCCCEEEEEECCCCC
APNLRKILEDKNITKIFHFARFDVSIIHYYLQTWALPCYCTKIASRLVRTYTDNHSLKEL
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHH
CLELLDIKLNKQQQSSDWGNENLTDKQKSYAASDVLYLHKIKEKLDLMLERENRKELAEK
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CFEFLPTRIELDSMGWGSVDIFNHHM
HHHHCCCEEEECCCCCCCEECCCCCC
>Mature Secondary Structure
MRIFIYKDDLPASAIPNDIKSIAVDTEAMGLLHSRDRLCLVQLSFNDGNAHLVQFKNDYT
CEEEEEECCCCCCCCCHHHHHHHCCHHHHHHHHCCCCEEEEEEEECCCCEEEEEECCCCC
APNLRKILEDKNITKIFHFARFDVSIIHYYLQTWALPCYCTKIASRLVRTYTDNHSLKEL
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHH
CLELLDIKLNKQQQSSDWGNENLTDKQKSYAASDVLYLHKIKEKLDLMLERENRKELAEK
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CFEFLPTRIELDSMGWGSVDIFNHHM
HHHHCCCEEEECCCCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]