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The map label for this gene is trx [H]

Identifier: 190571104

GI number: 190571104

Start: 770509

End: 770835

Strand: Reverse

Name: trx [H]

Synonym: WPa_0702

Alternate gene names: 190571104

Gene position: 770835-770509 (Counterclockwise)

Preceding gene: 190571105

Following gene: 190571102

Centisome position: 52.0

GC content: 38.53

Gene sequence:

>327_bases
ATGAGTGATGATATTAAAGCGGTAAATGATCAAAATTTCGAATCTGAAGTTGCTAACCACAAAGGATTTGTGCTGGTAGA
TTTTTGGGCAGAATGGTGTGGACCATGCAAAAGTCTGATGCCACGTATCGAGCAATTGGCTGAGGATAGAAAAGGCAAGA
TCAAGATCTGCAAGTTCGACATAGATGGAGAAACTGAAGTGCCAAGTAAGTATGGAGTTCAATCTATACCTACTTTAATC
ATATTTCAAGATGGTAAGGAAATTGCACGCAAAATTGGCGCAATAAATGATTTACACAGTTGGGTTGATAGTGAAATAAG
CGAGTAG

Upstream 100 bases:

>100_bases
ATCTTTAATCATCATATGTAATCACTTCACTTGAATCCAGAAAAATTTAGTTGATCAGCTGTTAATTGATACGCTATATT
TATAAAAATTTAGGTATTTT

Downstream 100 bases:

>100_bases
ACAAATTTCCTTTTGCGTGTATTATAGGTGTTGATAAAAGGGATTGTAGCTCAGTCGGTTAGAGCAGTTCGCTCATAACG
AATTGGTCGTAGGTTCGAGT

Product: thioredoxin

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 108; Mature: 107

Protein sequence:

>108_residues
MSDDIKAVNDQNFESEVANHKGFVLVDFWAEWCGPCKSLMPRIEQLAEDRKGKIKICKFDIDGETEVPSKYGVQSIPTLI
IFQDGKEIARKIGAINDLHSWVDSEISE

Sequences:

>Translated_108_residues
MSDDIKAVNDQNFESEVANHKGFVLVDFWAEWCGPCKSLMPRIEQLAEDRKGKIKICKFDIDGETEVPSKYGVQSIPTLI
IFQDGKEIARKIGAINDLHSWVDSEISE
>Mature_107_residues
SDDIKAVNDQNFESEVANHKGFVLVDFWAEWCGPCKSLMPRIEQLAEDRKGKIKICKFDIDGETEVPSKYGVQSIPTLII
FQDGKEIARKIGAINDLHSWVDSEISE

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI21361657, Length=86, Percent_Identity=43.0232558139535, Blast_Score=75, Evalue=1e-14,
Organism=Homo sapiens, GI21361403, Length=82, Percent_Identity=37.8048780487805, Blast_Score=74, Evalue=2e-14,
Organism=Homo sapiens, GI224493972, Length=106, Percent_Identity=33.0188679245283, Blast_Score=69, Evalue=8e-13,
Organism=Homo sapiens, GI42794771, Length=106, Percent_Identity=33.0188679245283, Blast_Score=68, Evalue=1e-12,
Organism=Homo sapiens, GI20070125, Length=86, Percent_Identity=34.8837209302326, Blast_Score=63, Evalue=4e-11,
Organism=Homo sapiens, GI5031973, Length=85, Percent_Identity=36.4705882352941, Blast_Score=63, Evalue=6e-11,
Organism=Homo sapiens, GI4758304, Length=82, Percent_Identity=37.8048780487805, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI87082331, Length=109, Percent_Identity=39.4495412844037, Blast_Score=101, Evalue=1e-23,
Organism=Escherichia coli, GI1788936, Length=85, Percent_Identity=37.6470588235294, Blast_Score=81, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI212646193, Length=94, Percent_Identity=37.2340425531915, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71980565, Length=87, Percent_Identity=37.9310344827586, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71980562, Length=87, Percent_Identity=37.9310344827586, Blast_Score=68, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17549970, Length=87, Percent_Identity=35.632183908046, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17569137, Length=87, Percent_Identity=40.2298850574713, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32566189, Length=87, Percent_Identity=40.2298850574713, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25144092, Length=89, Percent_Identity=34.8314606741573, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193209454, Length=87, Percent_Identity=40.2298850574713, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321648, Length=82, Percent_Identity=42.6829268292683, Blast_Score=75, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323072, Length=82, Percent_Identity=42.6829268292683, Blast_Score=74, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28573567, Length=83, Percent_Identity=38.5542168674699, Blast_Score=79, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21358065, Length=105, Percent_Identity=37.1428571428571, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24664269, Length=77, Percent_Identity=37.6623376623377, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17530795, Length=90, Percent_Identity=34.4444444444444, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24639826, Length=75, Percent_Identity=30.6666666666667, Blast_Score=65, Evalue=6e-12,
Organism=Drosophila melanogaster, GI19921434, Length=86, Percent_Identity=33.7209302325581, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI17647799, Length=96, Percent_Identity=38.5416666666667, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 12214; Mature: 12083

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDIKAVNDQNFESEVANHKGFVLVDFWAEWCGPCKSLMPRIEQLAEDRKGKIKICKFD
CCCCCCCCCCCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
IDGETEVPSKYGVQSIPTLIIFQDGKEIARKIGAINDLHSWVDSEISE
CCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDDIKAVNDQNFESEVANHKGFVLVDFWAEWCGPCKSLMPRIEQLAEDRKGKIKICKFD
CCCCCCCCCCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
IDGETEVPSKYGVQSIPTLIIFQDGKEIARKIGAINDLHSWVDSEISE
CCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10224002; 10984043 [H]