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The map label for this gene is trpS [H]

Identifier: 190570941

GI number: 190570941

Start: 561357

End: 562355

Strand: Reverse

Name: trpS [H]

Synonym: WPa_0522

Alternate gene names: 190570941

Gene position: 562355-561357 (Counterclockwise)

Preceding gene: 190570942

Following gene: 190570939

Centisome position: 37.93

GC content: 34.93

Gene sequence:

>999_bases
ATGGAAGAAGTTGTCTTCTCAGGTATTCAGCCAAGTGGAGTATTACACTTGGGCAATTATCTTGGTGCAATTAAGCAGTG
GATAGGCTTGCAGGATAAATATAAATCTCTTTTTTGTGTTGTTGATCTGCATGCAATCACAGCAAATAAGCTTCCCGCAA
ATGAATTAAAAAATAATATTTTTAAAGCAGCAGCAACTTATATTGCATGTGGAATAGATCCGGAAAAGTCGATTATTTTC
AATCAATCCGCAGTTAGTGGTCATGCAGAATTGGGCTGGCTGCTAGGGTGCTATACACCAATTGGTTGGCTTAATCGTAT
GACTCAATTTAAAGATAAGGCTGGAAGCGATAGACAAAAAGCTTCTCTTGGTTTATATAGCTACCCAGTACTTATGGCTG
CGGATATATTGCTGTATCAAACTAAATATGTTCCTGTTGGCGATGATCAAAAACAGCATTTAGAACTTGCACGTGATATT
GCATCAGCTTTTAACAATCATTATAAATGTAGTCATTTCATCATACCTGAAATCTTAACTTTGGATTGTACATCAAGGAT
AATGAGCTTAAGAGATGGAGCAAGCAAGATGAGCAAATCTGATTCTTCAGAATACTCATGCATTAACCTTGACGATACAG
ATGACTTGATTGTCAAGAAAATAGAAAAAGCAAAAACAGATTCAATTCTAGGCTTTGATTTTGCTACTTTAAAGTGCCGT
CCAGAAGTAAACAATTTGGTAAACGTTTATTCAGTGCTTAGTGATTTAAATGTGGAAAAAGTGTGTGAAGAAGTGAATAA
ACATGATATGAAACACTTTAAAAAAGAGTTAGCTGACTTAATCATCAGTGTTATATCACCCATACGTGAGAAGTTGAACG
GTCTTTTGAGGGATCAGCTCCATTTACATAAAATATTAAAAGAAGGTACAGAAAAAGCAGCAGAGATTGCAAATAACAAT
ATAAAAAAGATCAAGGATATTATAGGGTTTGTTCAATAG

Upstream 100 bases:

>100_bases
AACTGGTTATACCATTAAAAATAGGTTGCTTCGTCCTGCAATGGTTATTCTTTCTAAAAAATCTGCTGATTGCGAAAGTA
ACTAATAAAACACTCAAGGT

Downstream 100 bases:

>100_bases
GTTACAACTATTTCTTCCCATGGCTTTCAAATCGTGCAGCTATTTTCTTTACACTAACATGAGTGAGAAGAGGTTTTTTA
CTAACCGGAAGTTTAGAATC

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MEEVVFSGIQPSGVLHLGNYLGAIKQWIGLQDKYKSLFCVVDLHAITANKLPANELKNNIFKAAATYIACGIDPEKSIIF
NQSAVSGHAELGWLLGCYTPIGWLNRMTQFKDKAGSDRQKASLGLYSYPVLMAADILLYQTKYVPVGDDQKQHLELARDI
ASAFNNHYKCSHFIIPEILTLDCTSRIMSLRDGASKMSKSDSSEYSCINLDDTDDLIVKKIEKAKTDSILGFDFATLKCR
PEVNNLVNVYSVLSDLNVEKVCEEVNKHDMKHFKKELADLIISVISPIREKLNGLLRDQLHLHKILKEGTEKAAEIANNN
IKKIKDIIGFVQ

Sequences:

>Translated_332_residues
MEEVVFSGIQPSGVLHLGNYLGAIKQWIGLQDKYKSLFCVVDLHAITANKLPANELKNNIFKAAATYIACGIDPEKSIIF
NQSAVSGHAELGWLLGCYTPIGWLNRMTQFKDKAGSDRQKASLGLYSYPVLMAADILLYQTKYVPVGDDQKQHLELARDI
ASAFNNHYKCSHFIIPEILTLDCTSRIMSLRDGASKMSKSDSSEYSCINLDDTDDLIVKKIEKAKTDSILGFDFATLKCR
PEVNNLVNVYSVLSDLNVEKVCEEVNKHDMKHFKKELADLIISVISPIREKLNGLLRDQLHLHKILKEGTEKAAEIANNN
IKKIKDIIGFVQ
>Mature_332_residues
MEEVVFSGIQPSGVLHLGNYLGAIKQWIGLQDKYKSLFCVVDLHAITANKLPANELKNNIFKAAATYIACGIDPEKSIIF
NQSAVSGHAELGWLLGCYTPIGWLNRMTQFKDKAGSDRQKASLGLYSYPVLMAADILLYQTKYVPVGDDQKQHLELARDI
ASAFNNHYKCSHFIIPEILTLDCTSRIMSLRDGASKMSKSDSSEYSCINLDDTDDLIVKKIEKAKTDSILGFDFATLKCR
PEVNNLVNVYSVLSDLNVEKVCEEVNKHDMKHFKKELADLIISVISPIREKLNGLLRDQLHLHKILKEGTEKAAEIANNN
IKKIKDIIGFVQ

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=330, Percent_Identity=42.7272727272727, Blast_Score=270, Evalue=1e-72,
Organism=Homo sapiens, GI41352700, Length=181, Percent_Identity=50.2762430939227, Blast_Score=189, Evalue=3e-48,
Organism=Escherichia coli, GI1789786, Length=332, Percent_Identity=43.6746987951807, Blast_Score=282, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI71982800, Length=335, Percent_Identity=37.3134328358209, Blast_Score=227, Evalue=6e-60,
Organism=Caenorhabditis elegans, GI71982793, Length=333, Percent_Identity=36.9369369369369, Blast_Score=225, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6320474, Length=345, Percent_Identity=41.4492753623188, Blast_Score=246, Evalue=3e-66,
Organism=Drosophila melanogaster, GI24666151, Length=329, Percent_Identity=41.0334346504559, Blast_Score=251, Evalue=4e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37148; Mature: 37148

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEVVFSGIQPSGVLHLGNYLGAIKQWIGLQDKYKSLFCVVDLHAITANKLPANELKNNI
CCCCHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHEEHHHHHCCCCCHHHHHHHH
FKAAATYIACGIDPEKSIIFNQSAVSGHAELGWLLGCYTPIGWLNRMTQFKDKAGSDRQK
HHHHHHHHHCCCCCCCCEEECCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
ASLGLYSYPVLMAADILLYQTKYVPVGDDQKQHLELARDIASAFNNHYKCSHFIIPEILT
HHCCHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LDCTSRIMSLRDGASKMSKSDSSEYSCINLDDTDDLIVKKIEKAKTDSILGFDFATLKCR
HHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHCCCCEECCCEEEEEEC
PEVNNLVNVYSVLSDLNVEKVCEEVNKHDMKHFKKELADLIISVISPIREKLNGLLRDQL
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLHKILKEGTEKAAEIANNNIKKIKDIIGFVQ
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure
MEEVVFSGIQPSGVLHLGNYLGAIKQWIGLQDKYKSLFCVVDLHAITANKLPANELKNNI
CCCCHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHEEHHHHHCCCCCHHHHHHHH
FKAAATYIACGIDPEKSIIFNQSAVSGHAELGWLLGCYTPIGWLNRMTQFKDKAGSDRQK
HHHHHHHHHCCCCCCCCEEECCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
ASLGLYSYPVLMAADILLYQTKYVPVGDDQKQHLELARDIASAFNNHYKCSHFIIPEILT
HHCCHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LDCTSRIMSLRDGASKMSKSDSSEYSCINLDDTDDLIVKKIEKAKTDSILGFDFATLKCR
HHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHCCCCEECCCEEEEEEC
PEVNNLVNVYSVLSDLNVEKVCEEVNKHDMKHFKKELADLIISVISPIREKLNGLLRDQL
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLHKILKEGTEKAAEIANNNIKKIKDIIGFVQ
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]