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The map label for this gene is cisA [H]

Identifier: 190570784

GI number: 190570784

Start: 359359

End: 360657

Strand: Direct

Name: cisA [H]

Synonym: WPa_0342

Alternate gene names: 190570784

Gene position: 359359-360657 (Clockwise)

Preceding gene: 190570783

Following gene: 190570790

Centisome position: 24.24

GC content: 35.95

Gene sequence:

>1299_bases
ATGCTAAAAGAAGTAAGGTGTGCGATATATACAAGAAAATCAAATGAGGATGGGCTAGAACAAAAGTTTAACAGTCTTGA
TGCGCAGCGAGTAGCATGTGAAAAGTACATAAAGAGCAGAGAAGGCTGGGTAGCATTGGCAAAAAGGTACGATGATGGAG
GTTTCTCAGGAAAGAATTTAGAAAGACCAGCGATAAAGGGATTATTTGAAGATGTAAAAACAGGAGAAGTAGATTGTGTG
GTAGTATATACGCTAGACAGGTTATCAAGGGAAACAAAAGACAGCATTGAAGTAACATCATTTTTTAGAAGGCACCGAGT
AAATTTTGTAGCAGTAACGCAAATATTTGACAATAATACGCCAATGGGAAAGTTTGTACAAACAGTGTTATCAGGAGCAG
CACAACTAGAAAGAGAAATGATAGTAGAAAGGGTAAAAAATAAAATAGCAACATCAAAAGAGCAGGGATTATGGATGGGT
GGAACTTTACCGCTTGGGTATGATGTAAAAGATAAAGAATTAATAATAAATGAAAAAGAAGCGAAAATAGTAGGGCACAT
ATTTGAAAGATATTTGGAGCTAAAATCAATGGCAGAATTGGCAAGGGAGTTAAATAGTCAAGGATACCGGACAAAATCAG
ATATCTTTAAAAAAGCGACGGTAAGGAGAATAATAACAAATCCAATATATATGGGAAAAATCAAACATTATGAAAAAGAG
TATGAGGGAAAGCATGAAGCAATAATAGAAGAAGAAAAGTGGCAAAAAGCGCAGGAATTGATAAGGAATCAACCATATAG
AAAAGCAAAATATGAGGAAGCACTGCTTAGGGGAATAATTAAGTGCAAGAGCTGTGATGTGAATATGACACTGACATATG
CAAAAAAGGAGAATAAGAGATATCGATATTACGTATGCAACAATCATTTAAGGGGAAAAGGTTGTGAATCAGAAAACCGA
AATGTAATAGCAGGAGAAGTGGAAAAAGAAGTAATGAGGAAGACAGAGCAGCTATATGGAAAATTGGGAGAAAAAGCGGA
AGAGTGGAAAAATTTAAGCTTTGGAAAGCAAAAAGAAGTAGTGAAAAAGTTAATAAAGGGAGTAATGGTGAGAGAGGATG
GAATAGAGGTGAGTTTAGAGGATAAGGTGGAATTTATACCAATAAAAAAGAAAGGAAAGAAATGCACAGTAATTGAGCCA
GAAGGCAAAACAAACAATGCACTACTGAAAGCAGTGGTAAGGGCTCATCTGTGGAAACGTCGGGAATGTTCAAAAAAGTG
TGTCAAGCCGCATTTTTAG

Upstream 100 bases:

>100_bases
AATTTTTCACATCATTATCAGCAGTAGCCGGGAAAATAATGGGAATGAGCTACAACGGACCTTTATTATTCGGTATGCGT
GATAAAAATGAAAATTGAAA

Downstream 100 bases:

>100_bases
TTCAACTCAATTTTCAATCTGTTGGGAAAGAAGATATCAAGTTGAGACATAGTTAAAGCCCAATTAGGCAAAGGGGAGTG
TTCTGTAAACTGTGTCAAAC

Product: site-specific recombinase, resolvase family

Products: NA

Alternate protein names: Stage IV sporulation protein CA [H]

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MLKEVRCAIYTRKSNEDGLEQKFNSLDAQRVACEKYIKSREGWVALAKRYDDGGFSGKNLERPAIKGLFEDVKTGEVDCV
VVYTLDRLSRETKDSIEVTSFFRRHRVNFVAVTQIFDNNTPMGKFVQTVLSGAAQLEREMIVERVKNKIATSKEQGLWMG
GTLPLGYDVKDKELIINEKEAKIVGHIFERYLELKSMAELARELNSQGYRTKSDIFKKATVRRIITNPIYMGKIKHYEKE
YEGKHEAIIEEEKWQKAQELIRNQPYRKAKYEEALLRGIIKCKSCDVNMTLTYAKKENKRYRYYVCNNHLRGKGCESENR
NVIAGEVEKEVMRKTEQLYGKLGEKAEEWKNLSFGKQKEVVKKLIKGVMVREDGIEVSLEDKVEFIPIKKKGKKCTVIEP
EGKTNNALLKAVVRAHLWKRRECSKKCVKPHF

Sequences:

>Translated_432_residues
MLKEVRCAIYTRKSNEDGLEQKFNSLDAQRVACEKYIKSREGWVALAKRYDDGGFSGKNLERPAIKGLFEDVKTGEVDCV
VVYTLDRLSRETKDSIEVTSFFRRHRVNFVAVTQIFDNNTPMGKFVQTVLSGAAQLEREMIVERVKNKIATSKEQGLWMG
GTLPLGYDVKDKELIINEKEAKIVGHIFERYLELKSMAELARELNSQGYRTKSDIFKKATVRRIITNPIYMGKIKHYEKE
YEGKHEAIIEEEKWQKAQELIRNQPYRKAKYEEALLRGIIKCKSCDVNMTLTYAKKENKRYRYYVCNNHLRGKGCESENR
NVIAGEVEKEVMRKTEQLYGKLGEKAEEWKNLSFGKQKEVVKKLIKGVMVREDGIEVSLEDKVEFIPIKKKGKKCTVIEP
EGKTNNALLKAVVRAHLWKRRECSKKCVKPHF
>Mature_432_residues
MLKEVRCAIYTRKSNEDGLEQKFNSLDAQRVACEKYIKSREGWVALAKRYDDGGFSGKNLERPAIKGLFEDVKTGEVDCV
VVYTLDRLSRETKDSIEVTSFFRRHRVNFVAVTQIFDNNTPMGKFVQTVLSGAAQLEREMIVERVKNKIATSKEQGLWMG
GTLPLGYDVKDKELIINEKEAKIVGHIFERYLELKSMAELARELNSQGYRTKSDIFKKATVRRIITNPIYMGKIKHYEKE
YEGKHEAIIEEEKWQKAQELIRNQPYRKAKYEEALLRGIIKCKSCDVNMTLTYAKKENKRYRYYVCNNHLRGKGCESENR
NVIAGEVEKEVMRKTEQLYGKLGEKAEEWKNLSFGKQKEVVKKLIKGVMVREDGIEVSLEDKVEFIPIKKKGKKCTVIEP
EGKTNNALLKAVVRAHLWKRRECSKKCVKPHF

Specific function: Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of spoIIIC and spoIVCB to form sigma K factor [H]

COG id: COG1961

COG function: function code L; Site-specific recombinases, DNA invertase Pin homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 recombinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787404, Length=110, Percent_Identity=38.1818181818182, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011109
- InterPro:   IPR006118
- InterPro:   IPR006119 [H]

Pfam domain/function: PF07508 Recombinase; PF00239 Resolvase [H]

EC number: NA

Molecular weight: Translated: 50116; Mature: 50116

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKEVRCAIYTRKSNEDGLEQKFNSLDAQRVACEKYIKSREGWVALAKRYDDGGFSGKNL
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCC
ERPAIKGLFEDVKTGEVDCVVVYTLDRLSRETKDSIEVTSFFRRHRVNFVAVTQIFDNNT
CCHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCC
PMGKFVQTVLSGAAQLEREMIVERVKNKIATSKEQGLWMGGTLPLGYDVKDKELIINEKE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCEEECCCCCCCCCCCCCCEEECCHH
AKIVGHIFERYLELKSMAELARELNSQGYRTKSDIFKKATVRRIITNPIYMGKIKHYEKE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
YEGKHEAIIEEEKWQKAQELIRNQPYRKAKYEEALLRGIIKCKSCDVNMTLTYAKKENKR
HCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCE
YRYYVCNNHLRGKGCESENRNVIAGEVEKEVMRKTEQLYGKLGEKAEEWKNLSFGKQKEV
EEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
VKKLIKGVMVREDGIEVSLEDKVEFIPIKKKGKKCTVIEPEGKTNNALLKAVVRAHLWKR
HHHHHHHHEEECCCCEEEECCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
RECSKKCVKPHF
HHHHHHHCCCCC
>Mature Secondary Structure
MLKEVRCAIYTRKSNEDGLEQKFNSLDAQRVACEKYIKSREGWVALAKRYDDGGFSGKNL
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCC
ERPAIKGLFEDVKTGEVDCVVVYTLDRLSRETKDSIEVTSFFRRHRVNFVAVTQIFDNNT
CCHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCC
PMGKFVQTVLSGAAQLEREMIVERVKNKIATSKEQGLWMGGTLPLGYDVKDKELIINEKE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCEEECCCCCCCCCCCCCCEEECCHH
AKIVGHIFERYLELKSMAELARELNSQGYRTKSDIFKKATVRRIITNPIYMGKIKHYEKE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
YEGKHEAIIEEEKWQKAQELIRNQPYRKAKYEEALLRGIIKCKSCDVNMTLTYAKKENKR
HCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCE
YRYYVCNNHLRGKGCESENRNVIAGEVEKEVMRKTEQLYGKLGEKAEEWKNLSFGKQKEV
EEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
VKKLIKGVMVREDGIEVSLEDKVEFIPIKKKGKKCTVIEPEGKTNNALLKAVVRAHLWKR
HHHHHHHHEEECCCCEEEECCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
RECSKKCVKPHF
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2105293; 7704261; 8969508; 9384377 [H]